1
|
The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS.
|
Science
|
2013
|
6.34
|
2
|
Identification of human microRNA targets from isolated argonaute protein complexes.
|
RNA Biol
|
2007
|
4.96
|
3
|
Retracted
Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1.
|
Nature
|
2002
|
4.18
|
4
|
Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7.
|
Science
|
2007
|
4.18
|
5
|
Retracted
Noncoding RNAs of trithorax response elements recruit Drosophila Ash1 to Ultrabithorax.
|
Science
|
2006
|
4.10
|
6
|
Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells.
|
EMBO Rep
|
2007
|
3.89
|
7
|
Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death.
|
Cell Metab
|
2008
|
3.52
|
8
|
5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma.
|
Nat Med
|
2008
|
3.13
|
9
|
Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.
|
Cell
|
2009
|
2.98
|
10
|
Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies.
|
Acta Neuropathol
|
2009
|
2.76
|
11
|
Epstein-Barr virus-encoded microRNA miR-BART2 down-regulates the viral DNA polymerase BALF5.
|
Nucleic Acids Res
|
2007
|
2.74
|
12
|
CD103- and CD103+ bronchial lymph node dendritic cells are specialized in presenting and cross-presenting innocuous antigen to CD4+ and CD8+ T cells.
|
J Immunol
|
2007
|
2.61
|
13
|
Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance.
|
Nature
|
2006
|
2.40
|
14
|
ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons.
|
EMBO J
|
2010
|
2.35
|
15
|
DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells.
|
J Cell Biol
|
2007
|
2.20
|
16
|
A multifunctional human Argonaute2-specific monoclonal antibody.
|
RNA
|
2008
|
2.17
|
17
|
Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo.
|
J Exp Med
|
2008
|
2.15
|
18
|
CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II.
|
Science
|
2012
|
2.05
|
19
|
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome.
|
Nat Methods
|
2007
|
2.04
|
20
|
Chemotherapeutic drugs inhibit ribosome biogenesis at various levels.
|
J Biol Chem
|
2010
|
2.00
|
21
|
Chemokine receptor CCR9 contributes to the localization of plasma cells to the small intestine.
|
J Exp Med
|
2004
|
1.97
|
22
|
Systematic analysis of viral and cellular microRNA targets in cells latently infected with human gamma-herpesviruses by RISC immunoprecipitation assay.
|
Cell Host Microbe
|
2010
|
1.91
|
23
|
CCR6 and NK1.1 distinguish between IL-17A and IFN-gamma-producing gammadelta effector T cells.
|
Eur J Immunol
|
2009
|
1.83
|
24
|
Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins.
|
Acta Neuropathol
|
2013
|
1.82
|
25
|
The NHL-domain protein Wech is crucial for the integrin-cytoskeleton link.
|
Nat Cell Biol
|
2008
|
1.82
|
26
|
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells.
|
EMBO J
|
2003
|
1.78
|
27
|
Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin.
|
J Neurochem
|
2009
|
1.76
|
28
|
RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus.
|
J Neurosci
|
2010
|
1.76
|
29
|
CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus.
|
Blood
|
2009
|
1.73
|
30
|
Dendritic cells govern induction and reprogramming of polarized tissue-selective homing receptor patterns of T cells: important roles for soluble factors and tissue microenvironments.
|
Eur J Immunol
|
2005
|
1.73
|
31
|
Subunit stoichiometry of the CNG channel of rod photoreceptors.
|
Neuron
|
2002
|
1.71
|
32
|
Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation.
|
J Cell Biol
|
2005
|
1.69
|
33
|
The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility.
|
J Cell Biol
|
2008
|
1.63
|
34
|
Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus.
|
J Cell Sci
|
2003
|
1.62
|
35
|
Identification of novel downstream targets of platelet glycoprotein VI activation by differential proteome analysis: implications for thrombus formation.
|
Blood
|
2010
|
1.61
|
36
|
Progressive loss of PAX9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human oesophagus.
|
J Pathol
|
2002
|
1.60
|
37
|
Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection.
|
J Exp Med
|
2011
|
1.60
|
38
|
Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations.
|
Acta Neuropathol
|
2013
|
1.59
|
39
|
A pair of centromeric proteins mediates reproductive isolation in Drosophila species.
|
Dev Cell
|
2013
|
1.59
|
40
|
Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway.
|
Blood
|
2005
|
1.56
|
41
|
CCR9 is a homing receptor for plasmacytoid dendritic cells to the small intestine.
|
Proc Natl Acad Sci U S A
|
2007
|
1.56
|
42
|
A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses.
|
J Biol Chem
|
2010
|
1.55
|
43
|
Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation.
|
EMBO J
|
2012
|
1.55
|
44
|
Methanobactin reverses acute liver failure in a rat model of Wilson disease.
|
J Clin Invest
|
2016
|
1.52
|
45
|
Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.
|
RNA
|
2010
|
1.51
|
46
|
C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration.
|
Acta Neuropathol
|
2014
|
1.48
|
47
|
Thymic T cell development and progenitor localization depend on CCR7.
|
J Exp Med
|
2004
|
1.48
|
48
|
Cardiac pacemaker function of HCN4 channels in mice is confined to embryonic development and requires cyclic AMP.
|
EMBO J
|
2008
|
1.47
|
49
|
Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b.
|
J Biol Chem
|
2007
|
1.46
|
50
|
Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells.
|
Blood
|
2006
|
1.46
|
51
|
Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.
|
EMBO J
|
2012
|
1.45
|
52
|
Mouse phenotyping.
|
Methods
|
2010
|
1.43
|
53
|
T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire.
|
J Exp Med
|
2013
|
1.42
|
54
|
Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases.
|
Am J Pathol
|
2002
|
1.42
|
55
|
SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.
|
Nat Cell Biol
|
2009
|
1.42
|
56
|
Platelets contribute to postnatal occlusion of the ductus arteriosus.
|
Nat Med
|
2009
|
1.41
|
57
|
The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction.
|
Cell Microbiol
|
2007
|
1.41
|
58
|
Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex.
|
Nucleic Acids Res
|
2006
|
1.41
|
59
|
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.
|
J Cell Biol
|
2007
|
1.39
|
60
|
Pillars Article: CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs. Cell. 1999. 99: 23-33.
|
J Immunol
|
2016
|
1.39
|
61
|
Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration.
|
J Biol Chem
|
2012
|
1.37
|
62
|
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.
|
J Biol Chem
|
2014
|
1.37
|
63
|
Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells.
|
J Immunol
|
2002
|
1.34
|
64
|
Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression.
|
Nat Immunol
|
2010
|
1.33
|
65
|
Expression and nuclear localization of Snail, an E-cadherin repressor, in adenocarcinomas of the upper gastrointestinal tract.
|
Virchows Arch
|
2005
|
1.33
|
66
|
The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1.
|
Nucleic Acids Res
|
2011
|
1.32
|
67
|
Type 3a and type 3b OFF cone bipolar cells provide for the alternative rod pathway in the mouse retina.
|
J Comp Neurol
|
2007
|
1.31
|
68
|
Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit.
|
Mol Cell Biol
|
2007
|
1.31
|
69
|
Retinoic acid induces homing of protective T and B cells to the gut after subcutaneous immunization in mice.
|
J Clin Invest
|
2011
|
1.30
|
70
|
Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70.
|
J Transl Med
|
2007
|
1.30
|
71
|
Defects in 18 S or 28 S rRNA processing activate the p53 pathway.
|
J Biol Chem
|
2010
|
1.30
|
72
|
Helicobacter pylori induces MAPK phosphorylation and AP-1 activation via a NOD1-dependent mechanism.
|
J Immunol
|
2009
|
1.30
|
73
|
ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations.
|
Invest Ophthalmol Vis Sci
|
2009
|
1.30
|
74
|
PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation.
|
Oncogene
|
2005
|
1.30
|
75
|
Modulation of Nod2-dependent NF-kappaB signaling by the actin cytoskeleton.
|
J Cell Sci
|
2007
|
1.29
|
76
|
HCN channels are expressed differentially in retinal bipolar cells and concentrated at synaptic terminals.
|
Eur J Neurosci
|
2003
|
1.28
|
77
|
Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing.
|
Nat Struct Mol Biol
|
2008
|
1.26
|
78
|
Increased siRNA duplex stability correlates with reduced off-target and elevated on-target effects.
|
RNA
|
2011
|
1.26
|
79
|
Systemic first-line phenotyping.
|
Methods Mol Biol
|
2009
|
1.26
|
80
|
Platelet adhesion via glycoprotein IIb integrin is critical for atheroprogression and focal cerebral ischemia: an in vivo study in mice lacking glycoprotein IIb.
|
Circulation
|
2005
|
1.25
|
81
|
Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells.
|
Cell
|
2013
|
1.25
|
82
|
Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
|
Neurobiol Dis
|
2007
|
1.25
|
83
|
Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.
|
Hum Mol Genet
|
2010
|
1.25
|
84
|
Generalized multi-organ autoimmunity in CCR7-deficient mice.
|
Eur J Immunol
|
2007
|
1.23
|
85
|
Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody.
|
Proc Natl Acad Sci U S A
|
2010
|
1.21
|
86
|
Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.
|
Immunity
|
2013
|
1.21
|
87
|
Interactions of human Cdc45 with the Mcm2-7 complex, the GINS complex, and DNA polymerases delta and epsilon during S phase.
|
Genes Cells
|
2007
|
1.20
|
88
|
An atypical CNG channel activated by a single cGMP molecule controls sperm chemotaxis.
|
Sci Signal
|
2009
|
1.20
|
89
|
Dual cleavage of neuregulin 1 type III by BACE1 and ADAM17 liberates its EGF-like domain and allows paracrine signaling.
|
J Neurosci
|
2013
|
1.18
|
90
|
Angiostatic immune reaction in colorectal carcinoma: Impact on survival and perspectives for antiangiogenic therapy.
|
Int J Cancer
|
2008
|
1.17
|
91
|
Formation of She2p tetramers is required for mRNA binding, mRNP assembly, and localization.
|
RNA
|
2009
|
1.17
|
92
|
Downregulation of Sec23A protein by miRNA-375 in prostate carcinoma.
|
Mol Cancer Res
|
2011
|
1.17
|
93
|
Df31 protein and snoRNAs maintain accessible higher-order structures of chromatin.
|
Mol Cell
|
2012
|
1.17
|
94
|
A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein.
|
J Biol Chem
|
2008
|
1.17
|
95
|
Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation.
|
J Immunol
|
2009
|
1.17
|
96
|
Intracellular localization map of human herpesvirus 8 proteins.
|
J Virol
|
2007
|
1.16
|
97
|
Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo.
|
FASEB J
|
2003
|
1.16
|
98
|
The yeast Sup35NM domain propagates as a prion in mammalian cells.
|
Proc Natl Acad Sci U S A
|
2008
|
1.16
|
99
|
The viral interferon-regulatory factor-3 is required for the survival of KSHV-infected primary effusion lymphoma cells.
|
Blood
|
2007
|
1.16
|
100
|
Lymph node T cell homeostasis relies on steady state homing of dendritic cells.
|
Immunity
|
2011
|
1.15
|
101
|
Formin-like 1 (FMNL1) is regulated by N-terminal myristoylation and induces polarized membrane blebbing.
|
J Biol Chem
|
2009
|
1.15
|
102
|
Expression of the Epstein-Barr virus (EBV)-encoded latent membrane protein 2A (LMP2A) in EBV-associated nasopharyngeal carcinoma.
|
J Pathol
|
2004
|
1.14
|
103
|
dCHD3, a novel ATP-dependent chromatin remodeler associated with sites of active transcription.
|
Mol Cell Biol
|
2008
|
1.14
|
104
|
Stage-specific inhibition of MHC class I presentation by the Epstein-Barr virus BNLF2a protein during virus lytic cycle.
|
PLoS Pathog
|
2009
|
1.11
|
105
|
Epstein-Barr virus nuclear antigen 2 inhibits AID expression during EBV-driven B-cell growth.
|
Blood
|
2006
|
1.11
|
106
|
Protein kinase C delta induces Src kinase activity via activation of the protein tyrosine phosphatase PTP alpha.
|
J Biol Chem
|
2003
|
1.11
|
107
|
Polyclonal anti-PrP auto-antibodies induced with dimeric PrP interfere efficiently with PrPSc propagation in prion-infected cells.
|
J Biol Chem
|
2003
|
1.10
|
108
|
Identification of ZNF217, hnRNP-K, VEGF-A and IPO7 as targets for microRNAs that are downregulated in prostate carcinoma.
|
Int J Cancer
|
2012
|
1.10
|
109
|
Extensive co-operation between the Epstein-Barr virus EBNA3 proteins in the manipulation of host gene expression and epigenetic chromatin modification.
|
PLoS One
|
2010
|
1.10
|
110
|
Common pathobiochemical hallmarks of progranulin-associated frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis.
|
Acta Neuropathol
|
2014
|
1.10
|
111
|
PIASy-deficient mice display modest defects in IFN and Wnt signaling.
|
J Immunol
|
2004
|
1.10
|
112
|
The nucleoplasmin homolog NLP mediates centromere clustering and anchoring to the nucleolus.
|
Mol Cell
|
2013
|
1.09
|
113
|
Viral host-range factor C7 or K1 is essential for modified vaccinia virus Ankara late gene expression in human and murine cells, irrespective of their capacity to inhibit protein kinase R-mediated phosphorylation of eukaryotic translation initiation factor 2alpha.
|
J Gen Virol
|
2009
|
1.09
|
114
|
Differential gene expression patterns of EBV infected EBNA-3A positive and negative human B lymphocytes.
|
PLoS Pathog
|
2009
|
1.09
|
115
|
The human trithorax protein hASH2 functions as an oncoprotein.
|
Cancer Res
|
2008
|
1.08
|
116
|
Estrogen-dependent gene transcription in human breast cancer cells relies upon proteasome-dependent monoubiquitination of histone H2B.
|
Cancer Res
|
2011
|
1.08
|
117
|
Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y.
|
J Cell Biol
|
2010
|
1.08
|
118
|
Genome-associated RNA polymerase II includes the dissociable Rpb4/7 subcomplex.
|
J Biol Chem
|
2008
|
1.08
|
119
|
ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation.
|
Cell Commun Signal
|
2013
|
1.08
|
120
|
Aberrant ZNF423 impedes B cell differentiation and is linked to adverse outcome of ETV6-RUNX1 negative B precursor acute lymphoblastic leukemia.
|
J Exp Med
|
2013
|
1.07
|
121
|
The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein.
|
J Biol Chem
|
2010
|
1.06
|
122
|
Sex-dependent susceptibility to Listeria monocytogenes infection is mediated by differential interleukin-10 production.
|
Infect Immun
|
2005
|
1.06
|
123
|
Stable chromosomal association of MSL2 defines a dosage-compensated nuclear compartment.
|
Chromosoma
|
2005
|
1.06
|
124
|
System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency.
|
J Biol Chem
|
2010
|
1.06
|
125
|
Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay.
|
Nat Struct Mol Biol
|
2012
|
1.05
|
126
|
Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth.
|
Proc Natl Acad Sci U S A
|
2013
|
1.04
|
127
|
Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4.
|
FASEB J
|
2010
|
1.04
|
128
|
Attenuation of cell adhesion in lymphocytes is regulated by CYTIP, a protein which mediates signal complex sequestration.
|
EMBO J
|
2003
|
1.04
|
129
|
Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice.
|
J Clin Invest
|
2009
|
1.03
|
130
|
NSP4, an elastase-related protease in human neutrophils with arginine specificity.
|
Proc Natl Acad Sci U S A
|
2012
|
1.03
|
131
|
H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization.
|
Nucleic Acids Res
|
2012
|
1.03
|
132
|
O-linked N-acetylglucosaminylation of Sp1 inhibits the human immunodeficiency virus type 1 promoter.
|
J Virol
|
2009
|
1.03
|
133
|
A somatic knockout of CBF1 in a human B-cell line reveals that induction of CD21 and CCR7 by EBNA-2 is strictly CBF1 dependent and that downregulation of immunoglobulin M is partially CBF1 independent.
|
J Virol
|
2005
|
1.03
|
134
|
The sphingosine 1-phosphate receptor S1P4 regulates cell shape and motility via coupling to Gi and G12/13.
|
J Cell Biochem
|
2003
|
1.02
|
135
|
Allorestricted T cells with specificity for the FMNL1-derived peptide PP2 have potent antitumor activity against hematologic and other malignancies.
|
Blood
|
2007
|
1.02
|
136
|
Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68.
|
J Virol
|
2010
|
1.02
|
137
|
The E-cadherin repressor snail plays a role in tumor progression of endometrioid adenocarcinomas.
|
Diagn Mol Pathol
|
2007
|
1.02
|
138
|
Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10.
|
Nat Commun
|
2013
|
1.01
|
139
|
MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals.
|
PLoS Genet
|
2013
|
1.01
|
140
|
LST1 promotes the assembly of a molecular machinery responsible for tunneling nanotube formation.
|
J Cell Sci
|
2012
|
1.01
|
141
|
Phosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function.
|
Cell Cycle
|
2012
|
1.01
|
142
|
Heterogeneous expression of the adhesion receptor CD226 on murine NK and T cells and its function in NK-mediated killing of immature dendritic cells.
|
J Leukoc Biol
|
2009
|
1.01
|
143
|
dMec: a novel Mi-2 chromatin remodelling complex involved in transcriptional repression.
|
EMBO J
|
2009
|
1.01
|
144
|
Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis.
|
Nucleic Acids Res
|
2009
|
1.00
|
145
|
Structure-function analysis of the RNA helicase maleless.
|
Nucleic Acids Res
|
2007
|
0.99
|
146
|
Platelet GPVI binds to collagenous structures in the core region of human atheromatous plaque and is critical for atheroprogression in vivo.
|
Basic Res Cardiol
|
2008
|
0.99
|
147
|
Insulin-induced serine phosphorylation of IRS-2 via ERK1/2 and mTOR: studies on the function of Ser675 and Ser907.
|
Am J Physiol Endocrinol Metab
|
2010
|
0.99
|
148
|
mRNA silencing in human erythroid cell maturation: heterogeneous nuclear ribonucleoprotein K controls the expression of its regulator c-Src.
|
J Biol Chem
|
2008
|
0.98
|
149
|
Differential expression of activation-induced cytidine deaminase (AID) in nodular lymphocyte-predominant and classical Hodgkin lymphoma.
|
J Pathol
|
2005
|
0.98
|
150
|
Novel mouse mutants with primary cellular immunodeficiencies generated by genome-wide mutagenesis.
|
J Allergy Clin Immunol
|
2007
|
0.98
|
151
|
The Epstein-Barr virus EBNA-LP protein preferentially coactivates EBNA2-mediated stimulation of latent membrane proteins expressed from the viral divergent promoter.
|
J Virol
|
2005
|
0.97
|
152
|
Human replication protein A. The C-terminal RPA70 and the central RPA32 domains are involved in the interactions with the 3'-end of a primer-template DNA.
|
J Biol Chem
|
2003
|
0.97
|
153
|
The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing.
|
Nucleic Acids Res
|
2006
|
0.97
|
154
|
The nuclear organization of Polycomb/Trithorax group response elements in larval tissues of Drosophila melanogaster.
|
Chromosome Res
|
2008
|
0.97
|
155
|
Claudin k is specifically expressed in cells that form myelin during development of the nervous system and regeneration of the optic nerve in adult zebrafish.
|
Glia
|
2011
|
0.97
|
156
|
Monomethylation of lysine 20 on histone H4 facilitates chromatin maturation.
|
Mol Cell Biol
|
2008
|
0.97
|
157
|
Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains.
|
Structure
|
2013
|
0.97
|
158
|
The serotonergic phenotype is acquired by converging genetic mechanisms within the zebrafish central nervous system.
|
Dev Dyn
|
2007
|
0.97
|
159
|
Generation and characterization of a rat monoclonal antibody specific for multiple red fluorescent proteins.
|
Hybridoma (Larchmt)
|
2008
|
0.96
|
160
|
HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases.
|
Mol Cell
|
2013
|
0.96
|
161
|
The non-lysosomal β-glucosidase GBA2 is a non-integral membrane-associated protein at the endoplasmic reticulum (ER) and Golgi.
|
J Biol Chem
|
2012
|
0.96
|
162
|
Differential molecular and anatomical basis for B cell migration into the peritoneal cavity and omental milky spots.
|
J Immunol
|
2008
|
0.95
|
163
|
The adhesion receptor CD155 determines the magnitude of humoral immune responses against orally ingested antigens.
|
Eur J Immunol
|
2007
|
0.94
|
164
|
Kaposi's sarcoma-associated herpesvirus Lana-1 is a major activator of the serum response element and mitogen-activated protein kinase pathways via interactions with the Mediator complex.
|
J Gen Virol
|
2010
|
0.94
|
165
|
Protein arginine methylation during lytic adenovirus infection.
|
Biochem J
|
2004
|
0.93
|
166
|
A novel GGA-binding site is required for intracellular sorting mediated by stabilin-1.
|
Mol Cell Biol
|
2009
|
0.93
|
167
|
Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy.
|
Eur Heart J
|
2011
|
0.92
|
168
|
miR-142-3p is involved in CD25+ CD4 T cell proliferation by targeting the expression of glycoprotein A repetitions predominant.
|
J Immunol
|
2013
|
0.92
|
169
|
Developmental regulation of N-terminal H2B methylation in Drosophila melanogaster.
|
Nucleic Acids Res
|
2011
|
0.92
|
170
|
The Drosophila MBD2/3 protein mediates interactions between the MI-2 chromatin complex and CpT/A-methylated DNA.
|
Development
|
2004
|
0.91
|
171
|
A 49-kilodalton isoform of the adenovirus type 5 early region 1B 55-kilodalton protein is sufficient to support virus replication.
|
J Virol
|
2009
|
0.91
|
172
|
Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62.
|
Cell Commun Signal
|
2012
|
0.91
|
173
|
Differential up-regulation of cytosolic and membrane-bound heat shock protein 70 in tumor cells by anti-inflammatory drugs.
|
Clin Cancer Res
|
2004
|
0.91
|
174
|
Nuclei of chicken neurons in tissues and three-dimensional cell cultures are organized into distinct radial zones.
|
Chromosome Res
|
2011
|
0.91
|
175
|
Dendritic cells regulate T-cell deattachment through the integrin-interacting protein CYTIP.
|
Blood
|
2005
|
0.91
|
176
|
Co-aggregate formation of CADASIL-mutant NOTCH3: a single-particle analysis.
|
Hum Mol Genet
|
2011
|
0.91
|
177
|
EBV protein BNLF2a exploits host tail-anchored protein integration machinery to inhibit TAP.
|
J Immunol
|
2011
|
0.91
|
178
|
CD96 interaction with CD155 via its first Ig-like domain is modulated by alternative splicing or mutations in distal Ig-like domains.
|
J Biol Chem
|
2008
|
0.90
|
179
|
Dissection of cell cycle-dependent dynamics of Dnmt1 by FRAP and diffusion-coupled modeling.
|
Nucleic Acids Res
|
2013
|
0.90
|
180
|
E-cadherin regulates MAL-SRF-mediated transcription in epithelial cells.
|
J Cell Sci
|
2010
|
0.90
|
181
|
Drosophila Pur-α binds to trinucleotide-repeat containing cellular RNAs and translocates to the early oocyte.
|
RNA Biol
|
2012
|
0.90
|
182
|
Overexpression, purification, and biochemical characterization of the extracellular human CD83 domain and generation of monoclonal antibodies.
|
Protein Expr Purif
|
2002
|
0.90
|
183
|
Foamy virus envelope protein is a substrate for signal peptide peptidase-like 3 (SPPL3).
|
J Biol Chem
|
2012
|
0.90
|
184
|
CpG and LPS can interfere negatively with prion clearance in macrophage and microglial cells.
|
FEBS J
|
2007
|
0.90
|
185
|
Erythroid differentiation regulator (EDR), a novel, highly conserved factor I. Induction of haemoglobin synthesis in erythroleukaemic cells.
|
Cytokine
|
2004
|
0.90
|
186
|
H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1.
|
Hum Pathol
|
2009
|
0.90
|
187
|
Label-free LC-MSMS analysis of vitreous from autoimmune uveitis reveals a significant decrease in secreted Wnt signalling inhibitors DKK3 and SFRP2.
|
J Proteomics
|
2012
|
0.90
|
188
|
Expression of platelet collagen receptor glycoprotein VI is associated with acute coronary syndrome.
|
Eur Heart J
|
2006
|
0.88
|
189
|
Cell death triggered by alpha-emitting 213Bi-immunoconjugates in HSC45-M2 gastric cancer cells is different from apoptotic cell death.
|
Eur J Nucl Med Mol Imaging
|
2004
|
0.88
|
190
|
Human guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitis.
|
Am J Pathol
|
2006
|
0.88
|
191
|
Intramembrane proteolysis of GXGD-type aspartyl proteases is slowed by a familial Alzheimer disease-like mutation.
|
J Biol Chem
|
2008
|
0.88
|
192
|
Generation and characterization of rat and mouse monoclonal antibodies specific for MeCP2 and their use in X-inactivation studies.
|
PLoS One
|
2011
|
0.88
|
193
|
Functional allelic loss detected at the protein level in archival human tumours using allele-specific E-cadherin monoclonal antibodies.
|
J Pathol
|
2002
|
0.88
|
194
|
Human DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress.
|
J Biol Chem
|
2011
|
0.87
|
195
|
SETDB1 is involved in postembryonic DNA methylation and gene silencing in Drosophila.
|
PLoS One
|
2010
|
0.87
|
196
|
Generation and characterization of the first inhibitory antibody targeting tumour-associated carbonic anhydrase XII.
|
Cancer Immunol Immunother
|
2011
|
0.87
|
197
|
Mad1 function in cell proliferation and transcriptional repression is antagonized by cyclin E/CDK2.
|
J Biol Chem
|
2005
|
0.87
|
198
|
Developmental role for ACF1-containing nucleosome remodellers in chromatin organisation.
|
Development
|
2010
|
0.87
|
199
|
A unique secreted adenovirus E3 protein binds to the leukocyte common antigen CD45 and modulates leukocyte functions.
|
Proc Natl Acad Sci U S A
|
2013
|
0.86
|
200
|
Tolerance induction towards cardiac allografts under costimulation blockade is impaired in CCR7-deficient animals but can be restored by adoptive transfer of syngeneic plasmacytoid dendritic cells.
|
Eur J Immunol
|
2011
|
0.86
|
201
|
Direct evidence that the N-terminal extensions of the TAP complex act as autonomous interaction scaffolds for the assembly of the MHC I peptide-loading complex.
|
Cell Mol Life Sci
|
2012
|
0.86
|
202
|
SPOC1: a novel PHD-containing protein modulating chromatin structure and mitotic chromosome condensation.
|
J Cell Sci
|
2009
|
0.86
|
203
|
Prominent transcription of zebrafish N-myc (nmyc1) in tectal and retinal growth zones during embryonic and early larval development.
|
Gene Expr Patterns
|
2005
|
0.86
|
204
|
NLRP10 enhances Shigella-induced pro-inflammatory responses.
|
Cell Microbiol
|
2012
|
0.85
|
205
|
A new ELISA for the quantification of equine procalcitonin in plasma as potential inflammation biomarker in horses.
|
Anal Bioanal Chem
|
2014
|
0.85
|
206
|
Generation and characterization of a rat monoclonal antibody specific for PCNA.
|
Hybridoma (Larchmt)
|
2008
|
0.85
|
207
|
Expression of hairy/enhancer of split genes in neural progenitors and neurogenesis domains of the adult zebrafish brain.
|
J Comp Neurol
|
2011
|
0.85
|
208
|
Drosophila HP1c is regulated by an auto-regulatory feedback loop through its binding partner Woc.
|
PLoS One
|
2009
|
0.85
|
209
|
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 (vIRF4/K10) is a novel interaction partner of CSL/CBF1, the major downstream effector of Notch signaling.
|
J Virol
|
2010
|
0.85
|
210
|
Locoregional alpha-radioimmunotherapy of intraperitoneal tumor cell dissemination using a tumor-specific monoclonal antibody.
|
Clin Cancer Res
|
2003
|
0.84
|
211
|
Caspase-dependent cleavage of the mono-ADP-ribosyltransferase ARTD10 interferes with its pro-apoptotic function.
|
FEBS J
|
2013
|
0.84
|
212
|
CHD4/Mi-2beta activity is required for the positioning of the mesoderm/neuroectoderm boundary in Xenopus.
|
Genes Dev
|
2007
|
0.84
|
213
|
CRIS-a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bending.
|
PLoS Genet
|
2013
|
0.84
|
214
|
Asymmetric Arginine dimethylation of Epstein-Barr virus nuclear antigen 2 promotes DNA targeting.
|
Virology
|
2009
|
0.84
|
215
|
Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).
|
AIDS
|
2010
|
0.84
|
216
|
Prion protein/protein interactions: fusion with yeast Sup35p-NM modulates cytosolic PrP aggregation in mammalian cells.
|
FASEB J
|
2007
|
0.84
|
217
|
Minor histocompatibility antigens on canine hemopoietic progenitor cells.
|
J Immunol
|
2003
|
0.84
|
218
|
Deficient CCR7 signaling promotes TH2 polarization and B-cell activation in vivo.
|
Eur J Immunol
|
2011
|
0.83
|
219
|
Detection of wild type and deleted latent membrane protein 1 (LMP1) of Epstein-Barr virus in clinical biopsy material.
|
J Virol Methods
|
2004
|
0.83
|
220
|
Nucleosome remodeler SNF2L suppresses cell proliferation and migration and attenuates Wnt signaling.
|
Mol Cell Biol
|
2012
|
0.83
|
221
|
Abundance of follicular helper T cells in Peyer's patches is modulated by CD155.
|
Eur J Immunol
|
2009
|
0.83
|
222
|
Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex.
|
J Biol Chem
|
2010
|
0.83
|
223
|
EBNA2 amino acids 3 to 30 are required for induction of LMP-1 and immortalization maintenance.
|
J Virol
|
2004
|
0.83
|
224
|
Expression and localization of axin 2 in colorectal carcinoma and its clinical implication.
|
Int J Colorectal Dis
|
2013
|
0.82
|
225
|
The CALM and CALM/AF10 interactor CATS is a marker for proliferation.
|
Mol Oncol
|
2008
|
0.82
|
226
|
Atad3 function is essential for early post-implantation development in the mouse.
|
PLoS One
|
2013
|
0.82
|
227
|
A ubiquitin-specific protease possesses a decisive role for adenovirus replication and oncogene-mediated transformation.
|
PLoS Pathog
|
2013
|
0.82
|
228
|
Major retinal autoantigens remain stably expressed during all stages of spontaneous uveitis.
|
Mol Immunol
|
2007
|
0.81
|
229
|
The NP9 protein encoded by the human endogenous retrovirus HERV-K(HML-2) negatively regulates gene activation of the Epstein-Barr virus nuclear antigen 2 (EBNA2).
|
Int J Cancer
|
2011
|
0.81
|
230
|
Local delivery of soluble platelet collagen receptor glycoprotein VI inhibits thrombus formation in vivo.
|
Thromb Haemost
|
2006
|
0.81
|
231
|
ATP-competitive LRRK2 inhibitors interfere with monoclonal antibody binding to the kinase domain of LRRK2 under native conditions. A method to directly monitor the active conformation of LRRK2?
|
J Neurosci Methods
|
2013
|
0.81
|
232
|
Expression changes and novel interaction partners of talin 1 in effector cells of autoimmune uveitis.
|
J Proteome Res
|
2013
|
0.81
|
233
|
The protein kinase KIS impacts gene expression during development and fear conditioning in adult mice.
|
PLoS One
|
2012
|
0.81
|
234
|
Surface expression of collagen receptor Fc receptor-gamma/glycoprotein VI is enhanced on platelets in type 2 diabetes and mediates release of CD40 ligand and activation of endothelial cells.
|
Diabetes
|
2004
|
0.81
|
235
|
Homeodomain-interacting protein kinase 2-dependent repression of myogenic differentiation is relieved by its caspase-mediated cleavage.
|
Nucleic Acids Res
|
2013
|
0.81
|
236
|
Regulation of platelet glycoprotein VI (GPVI) surface expression and of soluble GPVI in patients with atrial fibrillation (AF) and acute coronary syndrome (ACS).
|
Basic Res Cardiol
|
2009
|
0.81
|
237
|
Influence of platelet count on the expression of platelet collagen receptor glycoprotein VI (GPVI) in patients with acute coronary syndrome.
|
Thromb Haemost
|
2009
|
0.81
|
238
|
Alterations of glucosylceramide-beta-glucosidase levels in the skin of patients with psoriasis vulgaris.
|
J Invest Dermatol
|
2004
|
0.81
|
239
|
Fltp(T2AiCre): a new knock-in mouse line for conditional gene targeting in distinct mono- and multiciliated tissues.
|
Differentiation
|
2011
|
0.80
|
240
|
NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection.
|
Eur J Immunol
|
2014
|
0.80
|
241
|
Binding of the heterogeneous ribonucleoprotein K (hnRNP K) to the Epstein-Barr virus nuclear antigen 2 (EBNA2) enhances viral LMP2A expression.
|
PLoS One
|
2012
|
0.80
|
242
|
The RNA helicase Rm62 cooperates with SU(VAR)3-9 to re-silence active transcription in Drosophila melanogaster.
|
PLoS One
|
2011
|
0.80
|
243
|
Biochemical characterisation of the proteins encoded by the DiGeorge critical region 6 (DGCR6) genes.
|
Hum Genet
|
2005
|
0.80
|
244
|
EXP3179 inhibits collagen-dependent platelet activation via glycoprotein receptor-VI independent of AT1-receptor antagonism: potential impact on atherothrombosis.
|
Arterioscler Thromb Vasc Biol
|
2007
|
0.80
|
245
|
Altered expression of talin 1 in peripheral immune cells points to a significant role of the innate immune system in spontaneous autoimmune uveitis.
|
J Proteomics
|
2012
|
0.80
|
246
|
Coordinated regulation of replication protein A activities by its subunits p14 and p32.
|
J Biol Chem
|
2004
|
0.80
|
247
|
Expression of viral and human dUTPase in Epstein-Barr virus-associated diseases.
|
J Med Virol
|
2002
|
0.80
|
248
|
Antitumor efficacy of a monoclonal antibody that inhibits the activity of cancer-associated carbonic anhydrase XII.
|
Cancer Res
|
2013
|
0.80
|
249
|
Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function.
|
Mamm Genome
|
2013
|
0.80
|
250
|
Rat monoclonal antibodies specific for LST1 proteins.
|
Hybridoma (Larchmt)
|
2009
|
0.79
|
251
|
Immunohistochemical detection of dUTPase in intracranial tumors.
|
Pathol Res Pract
|
2005
|
0.78
|
252
|
Development and characterization of new rat monoclonal antibodies for procalcitonin.
|
Anal Bioanal Chem
|
2008
|
0.78
|
253
|
Glycoprotein VI for diagnosis of acute coronary syndrome when ECG is ambiguous.
|
Int J Cardiol
|
2010
|
0.78
|
254
|
Enzyme-linked immunosorbent assays based on rabbit polyclonal and rat monoclonal antibodies against isoproturon.
|
J Agric Food Chem
|
2004
|
0.78
|
255
|
Toxic effects of intracerebral PrP antibody administration during the course of BSE infection in mice.
|
Prion
|
2007
|
0.78
|
256
|
Normal development in mice over-expressing the intracellular domain of DLL1 argues against reverse signaling by DLL1 in vivo.
|
PLoS One
|
2013
|
0.78
|
257
|
Platelet collagen receptor glycoprotein VI as a possible novel indicator for the acute coronary syndrome.
|
Am Heart J
|
2008
|
0.78
|
258
|
Loss of lambda2(315) transgene copy numbers influences the development of B1 cells.
|
Mol Immunol
|
2009
|
0.77
|
259
|
Expression of tumor necrosis factor receptor-associated factor 1 in nasopharyngeal carcinoma: possible upregulation by Epstein-Barr virus latent membrane protein 1.
|
Int J Cancer
|
2004
|
0.77
|
260
|
Influence of protein histidine phosphatase overexpression and down-regulation on human umbilical-vein endothelial cell viability.
|
Cell Biol Int
|
2012
|
0.77
|
261
|
Significance of individual amino acid residues for coenzyme and substrate specificity of 17beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus.
|
Chem Biol Interact
|
2003
|
0.77
|
262
|
Interferon Gamma Counteracts the Angiogenic Switch and Induces Vascular Permeability in Dextran Sulfate Sodium Colitis in Mice.
|
Inflamm Bowel Dis
|
2015
|
0.77
|
263
|
The putative Notch ligand HyJagged is a transmembrane protein present in all cell types of adult Hydra and upregulated at the boundary between bud and parent.
|
BMC Cell Biol
|
2011
|
0.77
|
264
|
The LARK/RBM4a protein is highly expressed in cerebellum as compared to cerebrum.
|
Neurosci Lett
|
2008
|
0.76
|
265
|
Dynamic interactions of Sup35p and PrP prion protein domains modulate aggregate nucleation and seeding.
|
Prion
|
2009
|
0.76
|
266
|
Targeting high-grade B cell lymphoma with CD19-specific T cells.
|
Int J Cancer
|
2014
|
0.76
|
267
|
Cloning and expression pattern of vat-1 homolog gene in zebrafish.
|
Gene Expr Patterns
|
2004
|
0.76
|
268
|
Development and characterization of rat monoclonal antibodies for N-acylated homoserine lactones.
|
Anal Bioanal Chem
|
2010
|
0.75
|
269
|
Np9, a cellular protein of retroviral ancestry restricted to human, chimpanzee and gorilla, binds and regulates ubiquitin ligase MDM2.
|
Cell Cycle
|
2015
|
0.75
|
270
|
Platelet glycoprotein VI (GPVI) for early identification of acute coronary syndrome in patients with chest pain.
|
Thromb Res
|
2010
|
0.75
|
271
|
The RNA-binding protein MARTA2 regulates dendritic targeting of MAP2 mRNAs in rat neurons.
|
J Neurochem
|
2013
|
0.75
|
272
|
Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.
|
Thromb Haemost
|
2017
|
0.75
|
273
|
Plasma levels of soluble glycoprotein VI (sGPVI) are associated with ischemic stroke.
|
Platelets
|
2012
|
0.75
|
274
|
In vitro generation of mature neutrophils from canine Lin- bone marrow cells.
|
Vet Immunol Immunopathol
|
2005
|
0.75
|
275
|
Sandwich immunoassay for soluble glycoprotein VI in patients with symptomatic coronary artery disease.
|
Clin Chem
|
2011
|
0.75
|
276
|
Extending the working range of immunoanalysis by exploitation of two monoclonal antibodies.
|
J Agric Food Chem
|
2004
|
0.75
|
277
|
Analysis of DDT isomers with enzyme-linked immunosorbent assay and optical immunosensor based on rat monoclonal antibodies as biological recognition elements.
|
J AOAC Int
|
2010
|
0.75
|
278
|
Multi-parameter determination of TNFα, PCT and CRP for point-of-care testing.
|
Analyst
|
2010
|
0.75
|
279
|
The adaptor protein Bam32 in human dendritic cells participates in the regulation of MHC class I-induced CD8+ T cell activation.
|
J Immunol
|
2011
|
0.75
|
280
|
Enzyme-linked immunosorbent assays for the sensitive analysis of 2,4-dinitroaniline and 2,6-dinitroaniline in water and soil.
|
Anal Bioanal Chem
|
2008
|
0.75
|
281
|
Development of new rat monoclonal antibodies with different selectivities and sensitivities for 2,4,6-trinitrotoluene (TNT) and other nitroaromatic compounds.
|
Anal Bioanal Chem
|
2005
|
0.75
|