Published in J Biol Chem on March 25, 2009
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ASC, which is composed of a PYD and a CARD, is up-regulated by inflammation and apoptosis in human neutrophils. Biochem Biophys Res Commun (2002) 1.16
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Methylation of the ASC gene promoter is associated with aggressive prostate cancer. Prostate (2006) 0.94
GA-binding protein and p300 are essential components of a retinoic acid-induced enhanceosome in myeloid cells. Mol Cell Biol (2006) 0.92
Regulation of the rat thyrotropin receptor gene by the methylation-sensitive transcription factor GA-binding protein. Mol Endocrinol (1998) 0.90
Dual role of TMS1/ASC in death receptor signaling. Oncogene (2006) 0.90
Silencing of TMS1/ASC promotes resistance to anoikis in breast epithelial cells. Cancer Res (2009) 0.89
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Purification and mass spectrometric identification of GA-binding protein (GABP) as the functional pituitary Ets factor binding to the basal transcription element of the prolactin promoter. J Biol Chem (2003) 0.83
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Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma. Am J Pathol (2004) 1.58
Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes. Cancer Res (2006) 1.58
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DNA motifs associated with aberrant CpG island methylation. Genomics (2006) 1.40
Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation. Int J Cancer (2011) 1.39
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Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells. Mol Cancer Res (2008) 1.30
LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins. Cancer Res (2008) 1.28
The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity. Cancer Res (2008) 1.26
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Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity. Cancer Res (2008) 1.05
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Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses. Pituitary (2008) 1.00
Effects of methylation on expression of TMS1/ASC in human breast cancer cells. Oncogene (2003) 1.00
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Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture. J Biol Chem (2001) 0.99
Homozygous deletion of the STK11/LKB1 locus and the generation of novel fusion transcripts in cervical cancer cells. Cancer Genet Cytogenet (2010) 0.97
Overexpression of MBD2 in glioblastoma maintains epigenetic silencing and inhibits the antiangiogenic function of the tumor suppressor gene BAI1. Cancer Res (2011) 0.97
Class I HDACs are mediators of smoke carcinogen-induced stabilization of DNMT1 and serve as promising targets for chemoprevention of lung cancer. Cancer Prev Res (Phila) (2014) 0.97
Silencing of TMS1/ASC promotes resistance to anoikis in breast epithelial cells. Cancer Res (2009) 0.89
Withania somnifera root extract inhibits mammary cancer metastasis and epithelial to mesenchymal transition. PLoS One (2013) 0.85
IL-4 induces the proteolytic processing of mast cell STAT6. J Immunol (2002) 0.83
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A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing. J Biol Chem (2014) 0.82
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Dysregulation of mTOR activity through LKB1 inactivation. Chin J Cancer (2013) 0.81
An intron GATA-binding site regulates chromatin accessibility and is essential for IL-4 gene expression in mast cells. Eur J Immunol (2005) 0.81
Folate-related gene variants in Irish families affected by neural tube defects. Front Genet (2013) 0.80
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Periconceptional folic acid and risk of autism spectrum disorders. JAMA (2013) 0.79
Epigenetic regulation of MDR1 gene in breast cancer: CpG methylation status dominates the stable maintenance of a silent gene. Cancer Biol Ther (2004) 0.79
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Hypomethylation of serum blood clot DNA, but not plasma EDTA-blood cell pellet DNA, from vitamin B12-deficient subjects. PLoS One (2013) 0.75