Published in Glycobiology on April 06, 2009
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Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers. Neuron (2009) 1.96
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Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice. Brain (2010) 1.90
Recognition of sialylated meningococcal lipopolysaccharide by siglecs expressed on myeloid cells leads to enhanced bacterial uptake. Mol Microbiol (2003) 1.87
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Deficits in axonal transport precede ALS symptoms in vivo. Proc Natl Acad Sci U S A (2010) 1.66
The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis. Nat Med (2010) 1.63
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Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population. Nat Immunol (2007) 1.48
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Presynaptic receptor arrays for clostridial neurotoxins. Trends Microbiol (2004) 1.42
A hitchhiker's guide to the nervous system: the complex journey of viruses and toxins. Nat Rev Microbiol (2010) 1.39
Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis. J Immunol (2009) 1.39
Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR. J Cell Biol (2002) 1.38
Long chain polyunsaturated fatty acids are required for efficient neurotransmission in C. elegans. J Cell Sci (2003) 1.38
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Botulinum neurotoxins: from paralysis to recovery of functional neuromuscular transmission. J Physiol Paris (2001) 1.36
The autoreactivity of anti-phosphorylcholine antibodies for atherosclerosis-associated neo-antigens and apoptotic cells. J Immunol (2003) 1.36
CAR-associated vesicular transport of an adenovirus in motor neuron axons. PLoS Pathog (2009) 1.35
Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec-7-dependent and -independent mechanisms. Eur J Immunol (2003) 1.35
Dendritic cell maturation results in pronounced changes in glycan expression affecting recognition by siglecs and galectins. J Immunol (2007) 1.34
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Structural, expression, and evolutionary analysis of mouse CIAS1. Gene (2004) 1.33
Interaction of tau protein with the dynactin complex. EMBO J (2007) 1.33
Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies. J Allergy Clin Immunol (2007) 1.32
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Coordinated regulation of AP2 uncoating from clathrin-coated vesicles by rab5 and hRME-6. J Cell Biol (2008) 1.31
Sialoadhesin-deficient mice exhibit subtle changes in B- and T-cell populations and reduced immunoglobulin M levels. Mol Cell Biol (2006) 1.29
Galectin-3 deficiency reduces the severity of experimental autoimmune encephalomyelitis. J Immunol (2009) 1.28
The dystonia-associated protein torsinA modulates synaptic vesicle recycling. J Biol Chem (2007) 1.23
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Molecular landmarks along the axonal route: axonal transport in health and disease. Curr Opin Cell Biol (2008) 1.23
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Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production. J Immunol (2009) 1.23
A small region of the natural killer cell receptor, Siglec-7, is responsible for its preferred binding to alpha 2,8-disialyl and branched alpha 2,6-sialyl residues. A comparison with Siglec-9. J Biol Chem (2001) 1.22
Individual plasmacytoid dendritic cells are major contributors to the production of multiple innate cytokines in an organ-specific manner during viral infection. Int Immunol (2007) 1.22
Spastin and microtubules: Functions in health and disease. J Neurosci Res (2007) 1.22
The M/GP(5) glycoprotein complex of porcine reproductive and respiratory syndrome virus binds the sialoadhesin receptor in a sialic acid-dependent manner. PLoS Pathog (2010) 1.22
Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells. Mol Cell Biol (2005) 1.21
CD169 mediates the capture of exosomes in spleen and lymph node. Blood (2013) 1.20
Cloning and characterization of human Siglec-11. A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia. J Biol Chem (2002) 1.20
Myosin Va and microtubule-based motors are required for fast axonal retrograde transport of tetanus toxin in motor neurons. J Cell Sci (2003) 1.20
Sialoadhesin promotes the inflammatory response in experimental autoimmune uveoretinitis. J Immunol (2006) 1.20
SOCS3 targets Siglec 7 for proteasomal degradation and blocks Siglec 7-mediated responses. J Biol Chem (2006) 1.16
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Human spastin has multiple microtubule-related functions. J Neurochem (2005) 1.16
Siglec-5 (CD170) can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation. J Biol Chem (2005) 1.16
Sialoadhesin-positive macrophages bind regulatory T cells, negatively controlling their expansion and autoimmune disease progression. J Immunol (2009) 1.16
Phosphatidylinositol 3-kinase C2alpha is essential for ATP-dependent priming of neurosecretory granule exocytosis. Mol Biol Cell (2005) 1.16
Ganglioside antibodies and neuropathies. Curr Opin Neurol (2008) 1.15
Sialoadhesin promotes rapid proinflammatory and type I IFN responses to a sialylated pathogen, Campylobacter jejuni. J Immunol (2012) 1.14
Tetanus toxin is transported in a novel neuronal compartment characterized by a specialized pH regulation. J Biol Chem (2005) 1.14
Neurotrophins Redirect p75NTR from a clathrin-independent to a clathrin-dependent endocytic pathway coupled to axonal transport. Traffic (2007) 1.14
Cardiovascular disease in autoimmune rheumatic diseases. Autoimmun Rev (2013) 1.14
Tolerance to self gangliosides is the major factor restricting the antibody response to lipopolysaccharide core oligosaccharides in Campylobacter jejuni strains associated with Guillain-Barré syndrome. Infect Immun (2002) 1.13
Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b β2-integrin-dependent signaling. Blood (2013) 1.13
Characterization of the specific interaction between sialoadhesin and sialylated Campylobacter jejuni lipooligosaccharides. Infect Immun (2010) 1.13
High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family. J Biol Chem (2002) 1.12
Eosinophil-selective binding and proapoptotic effect in vitro of a synthetic Siglec-8 ligand, polymeric 6'-sulfated sialyl Lewis x. J Pharmacol Exp Ther (2009) 1.12
Elimination of plasma membrane phosphatidylinositol (4,5)-bisphosphate is required for exocytosis from mast cells. J Cell Sci (2006) 1.10
Human Siglec-10 can bind to vascular adhesion protein-1 and serves as its substrate. Blood (2009) 1.10
Anti-disialoside antibodies kill perisynaptic Schwann cells and damage motor nerve terminals via membrane attack complex in a murine model of neuropathy. Brain (2004) 1.10
Immunolocalization of GQ1b and related gangliosides in human extraocular neuromuscular junctions and muscle spindles. Invest Ophthalmol Vis Sci (2009) 1.09
Siglec-7 undergoes a major conformational change when complexed with the alpha(2,8)-disialylganglioside GT1b. J Biol Chem (2006) 1.09
MUC1 is a counter-receptor for myelin-associated glycoprotein (Siglec-4a) and their interaction contributes to adhesion in pancreatic cancer perineural invasion. Cancer Res (2007) 1.09
Advances in understanding and treatment of immune-mediated disorders of the peripheral nervous system. Muscle Nerve (2004) 1.09
A versatile gold surface approach for fabrication and interrogation of glycoarrays. Chembiochem (2008) 1.08
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Surface plasmon resonance imaging for real-time, label-free analysis of protein interactions with carbohydrate microarrays. Glycoconj J (2007) 1.06
Campylobacter jejuni lipooligosaccharides modulate dendritic cell-mediated T cell polarization in a sialic acid linkage-dependent manner. Infect Immun (2011) 1.06
Complex gangliosides at the neuromuscular junction are membrane receptors for autoantibodies and botulinum neurotoxin but redundant for normal synaptic function. J Neurosci (2002) 1.05
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Sialoadhesin in recognition of self and non-self. Semin Immunopathol (2012) 1.05
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