Published in Neuron on October 19, 2006
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Rab7 mutants associated with Charcot-Marie-Tooth disease cause delayed growth factor receptor transport and altered endosomal and nuclear signaling. J Biol Chem (2012) 0.96
p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity. Proc Natl Acad Sci U S A (2012) 0.96
Regulation of trafficking of activated TrkA is critical for NGF-mediated functions. Traffic (2011) 0.96
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Snapin deficiency is associated with developmental defects of the central nervous system. Biosci Rep (2011) 0.82
Semaphorin 3A activates the guanosine triphosphatase Rab5 to promote growth cone collapse and organize callosal axon projections. Sci Signal (2014) 0.81
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Palmitoylation controls DLK localization, interactions and activity to ensure effective axonal injury signaling. Proc Natl Acad Sci U S A (2015) 0.81
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The p75 neurotrophin receptor evades the endolysosomal route in neuronal cells, favouring multivesicular bodies specialised for exosomal release. J Cell Sci (2014) 0.80
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Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis. Genes Dev (2002) 5.15
Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science (2003) 4.40
Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry. Proteomics (2004) 2.43
Activation of MDA5 requires higher-order RNA structures generated during virus infection. J Virol (2009) 2.37
Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP. Mol Cell Biol (2003) 2.33
Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect. Proteomics (2003) 2.17
Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. Mol Cell Biol (2003) 2.03
A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice. J Cell Biol (2005) 2.01
Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2). Biochem J (2009) 2.00
Purification and characterization of the human elongator complex. J Biol Chem (2001) 1.97
Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers. Neuron (2009) 1.96
Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures. Science (2005) 1.92
The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily. Biochem J (2008) 1.74
Structure and chemical inhibition of the RET tyrosine kinase domain. J Biol Chem (2006) 1.72
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Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles. Mol Biol Cell (2004) 1.56
Regulation of endocytic recycling of KCNQ1/KCNE1 potassium channels. Circ Res (2007) 1.52
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Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease. J Neurosci (2008) 1.44
Presynaptic receptor arrays for clostridial neurotoxins. Trends Microbiol (2004) 1.42
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Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR. J Cell Biol (2002) 1.38
Long chain polyunsaturated fatty acids are required for efficient neurotransmission in C. elegans. J Cell Sci (2003) 1.38
Botulinum neurotoxins: from paralysis to recovery of functional neuromuscular transmission. J Physiol Paris (2001) 1.36
CAR-associated vesicular transport of an adenovirus in motor neuron axons. PLoS Pathog (2009) 1.35
CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76. Mol Cell Biol (2006) 1.35
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Coordinated regulation of AP2 uncoating from clathrin-coated vesicles by rab5 and hRME-6. J Cell Biol (2008) 1.31
RILP is required for the proper morphology and function of late endosomes. J Cell Sci (2007) 1.26
The Neisseria meningitidis capsule is important for intracellular survival in human cells. Infect Immun (2007) 1.25
The dystonia-associated protein torsinA modulates synaptic vesicle recycling. J Biol Chem (2007) 1.23
The journey of tetanus and botulinum neurotoxins in neurons. Trends Microbiol (2003) 1.23
Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1. J Cell Biol (2006) 1.23
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Spastin and microtubules: Functions in health and disease. J Neurosci Res (2007) 1.22
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Myosin Va and microtubule-based motors are required for fast axonal retrograde transport of tetanus toxin in motor neurons. J Cell Sci (2003) 1.20
Rab7b controls trafficking from endosomes to the TGN. J Cell Sci (2010) 1.20
Human spastin has multiple microtubule-related functions. J Neurochem (2005) 1.16
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Pak1 phosphorylation on t212 affects microtubules in cells undergoing mitosis. Curr Biol (2002) 1.15
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Tetanus toxin is transported in a novel neuronal compartment characterized by a specialized pH regulation. J Biol Chem (2005) 1.14
Neurotrophins Redirect p75NTR from a clathrin-independent to a clathrin-dependent endocytic pathway coupled to axonal transport. Traffic (2007) 1.14
Mycobacterium bovis BCG disrupts the interaction of Rab7 with RILP contributing to inhibition of phagosome maturation. J Leukoc Biol (2007) 1.11
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Elimination of plasma membrane phosphatidylinositol (4,5)-bisphosphate is required for exocytosis from mast cells. J Cell Sci (2006) 1.10
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Kidins220/ARMS regulates Rac1-dependent neurite outgrowth by direct interaction with the RhoGEF Trio. J Cell Sci (2010) 1.05
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Identification of a meningococcal L-glutamate ABC transporter operon essential for growth in low-sodium environments. Infect Immun (2006) 1.03
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Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons. PLoS Pathog (2012) 1.00
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Proteomic identification of a role for the von Hippel Lindau tumour suppressor in changes in the expression of mitochondrial proteins and septin 2 in renal cell carcinoma. Proteomics (2006) 0.92
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CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent process. EMBO J (2010) 0.90
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Characterization of the Rab7K157N mutant protein associated with Charcot-Marie-Tooth type 2B. Biochem Biophys Res Commun (2008) 0.89
The Rab-interacting lysosomal protein, a Rab7 and Rab34 effector, is capable of self-interaction. Biochem Biophys Res Commun (2005) 0.89