Published in BMC Genomics on April 07, 2009
MicroRNAs and their isomiRs function cooperatively to target common biological pathways. Genome Biol (2011) 2.15
A systematic analysis of the skeletal muscle miRNA transcriptome of chicken varieties with divergent skeletal muscle growth identifies novel miRNAs and differentially expressed miRNAs. BMC Genomics (2011) 1.20
Sterol regulatory element binding protein and dietary lipid regulation of fatty acid synthesis in the mammary epithelium. Am J Physiol Endocrinol Metab (2010) 1.02
The epigenetic landscape of mammary gland development and functional differentiation. J Mammary Gland Biol Neoplasia (2010) 1.02
Beta cell 5'-shifted isomiRs are candidate regulatory hubs in type 2 diabetes. PLoS One (2013) 0.99
A Review of Computational Tools in microRNA Discovery. Front Genet (2013) 0.98
Comparative transcriptome profiling of dairy goat microRNAs from dry period and peak lactation mammary gland tissues. PLoS One (2012) 0.93
Progestin regulated miRNAs that mediate progesterone receptor action in breast cancer. Mol Cell Endocrinol (2012) 0.92
Discovery and characterization of novel microRNAs during endothelial differentiation of human embryonic stem cells. Stem Cells Dev (2012) 0.89
miR-34a expression, epigenetic regulation, and function in human placental diseases. Epigenetics (2013) 0.86
Nitroso-redox balance and mitochondrial homeostasis are regulated by STOX1, a pre-eclampsia-associated gene. Antioxid Redox Signal (2014) 0.86
Characterisation and comparison of lactating mouse and bovine mammary gland miRNomes. PLoS One (2014) 0.84
A comprehensive microRNA expression profile of the backfat tissue from castrated and intact full-sib pair male pigs. BMC Genomics (2014) 0.82
Small RNA Sequencing Uncovers New miRNAs and moRNAs Differentially Expressed in Normal and Primary Myelofibrosis CD34+ Cells. PLoS One (2015) 0.79
DeAnnIso: a tool for online detection and annotation of isomiRs from small RNA sequencing data. Nucleic Acids Res (2016) 0.78
miRNA transcriptome of hypertrophic skeletal muscle with overexpressed myostatin propeptide. Biomed Res Int (2014) 0.76
Characterizing isomiR variants within the microRNA-34/449 family. FEBS Lett (2017) 0.75
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res (1994) 392.47
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
Genomic sequencing. Proc Natl Acad Sci U S A (1984) 92.36
Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res (2003) 77.89
MicroRNA expression profiles classify human cancers. Nature (2005) 69.12
The functions of animal microRNAs. Nature (2004) 64.85
Identification of novel genes coding for small expressed RNAs. Science (2001) 44.44
A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A (2006) 40.09
miRBase: tools for microRNA genomics. Nucleic Acids Res (2007) 38.61
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci U S A (1992) 35.45
A mammalian microRNA expression atlas based on small RNA library sequencing. Cell (2007) 34.03
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science (2001) 31.33
MicroRNA gene expression deregulation in human breast cancer. Cancer Res (2005) 27.56
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev (2001) 21.82
The widespread impact of mammalian MicroRNAs on mRNA repression and evolution. Science (2005) 20.51
A uniform system for microRNA annotation. RNA (2003) 20.28
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature (2000) 19.15
Vertebrate microRNA genes. Science (2003) 17.42
Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res (2003) 17.13
Switching from repression to activation: microRNAs can up-regulate translation. Science (2007) 17.00
Identification of hundreds of conserved and nonconserved human microRNAs. Nat Genet (2005) 15.96
Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell (2006) 15.12
An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues. Proc Natl Acad Sci U S A (2004) 13.66
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol Cell (2002) 10.30
miR-21-mediated tumor growth. Oncogene (2006) 9.90
Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs. Genome Res (2007) 9.61
Second-generation shRNA libraries covering the mouse and human genomes. Nat Genet (2005) 8.23
Genomics of microRNA. Trends Genet (2006) 7.75
Diversity of microRNAs in human and chimpanzee brain. Nat Genet (2006) 6.57
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol (2007) 6.41
Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies. Mol Cancer (2006) 5.47
Facile means for quantifying microRNA expression by real-time PCR. Biotechniques (2005) 5.04
Clustering and conservation patterns of human microRNAs. Nucleic Acids Res (2005) 4.79
RNA editing of human microRNAs. Genome Biol (2006) 4.16
Retracted MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer. J Biol Chem (2008) 3.63
Information networks in the mammary gland. Nat Rev Mol Cell Biol (2005) 3.57
Identification and characterization of small RNAs involved in RNA silencing. FEBS Lett (2005) 3.39
The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines. Mol Endocrinol (2007) 3.39
Prediction and validation of microRNAs and their targets. FEBS Lett (2005) 2.99
Mammary development in the embryo and adult: a journey of morphogenesis and commitment. Development (2008) 2.69
A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells. Genes Dev (2007) 2.48
Cloning and expression profiling of testis-expressed microRNAs. Dev Biol (2007) 2.00
A PCR-based method for detection and quantification of small RNAs. Biochem Biophys Res Commun (2006) 1.91
Cloning and expression profiling of small RNAs expressed in the mouse ovary. RNA (2007) 1.65
MicroRNA (miRNA) cloning analysis reveals sex differences in miRNA expression profiles between adult mouse testis and ovary. Reproduction (2008) 1.44
Identification and characterization of microRNAs from the bovine adipose tissue and mammary gland. FEBS Lett (2007) 1.32
MicroRNA involvement in mammary gland development and breast cancer. Reprod Nutr Dev (2006) 1.21
Identification and characterization of new microRNAs from pig. Mamm Genome (2008) 1.00
Identification of differentially expressed microRNAs during the development of Chinese murine mammary gland. J Genet Genomics (2007) 0.98
A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes. Proc Natl Acad Sci U S A (2005) 2.47
Facilitated cross-species transmission of prions in extraneural tissue. Science (2012) 2.26
Methemoglobinemia: from diagnosis to treatment. Rev Bras Anestesiol (2008) 2.24
Metapopulation dynamics and spatial heterogeneity in cancer. Proc Natl Acad Sci U S A (2002) 2.17
Prion agent diversity and species barrier. Vet Res (2008) 1.80
A bovine prion acquires an epidemic bovine spongiform encephalopathy strain-like phenotype on interspecies transmission. J Neurosci (2007) 1.75
A physical map of the bovine genome. Genome Biol (2007) 1.56
Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy. PLoS Pathog (2006) 1.55
Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias. Proc Natl Acad Sci U S A (2002) 1.44
Zinc finger nuclease technology heralds a new era in mammalian transgenesis. Trends Biotechnol (2009) 1.38
Transmission of atypical bovine prions to mice transgenic for human prion protein. Emerg Infect Dis (2008) 1.38
Prominent and persistent extraneural infection in human PrP transgenic mice infected with variant CJD. PLoS One (2008) 1.24
MicroRNA involvement in mammary gland development and breast cancer. Reprod Nutr Dev (2006) 1.21
Cultured peripheral neuroglial cells are highly permissive to sheep prion infection. J Virol (2004) 1.19
The challenge of corporatisation: the experience of Portuguese public hospitals. Eur J Health Econ (2009) 1.05
The prion or the related Shadoo protein is required for early mouse embryogenesis. FEBS Lett (2009) 1.03
High PTP4A3 phosphatase expression correlates with metastatic risk in uveal melanoma patients. Cancer Res (2010) 1.02
Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive disease aspects. Arthritis Res Ther (2011) 1.01
R-spondin1 is required for normal epithelial morphogenesis during mammary gland development. Biochem Biophys Res Commun (2009) 1.00
A second generation radiation hybrid map to aid the assembly of the bovine genome sequence. BMC Genomics (2006) 0.99
New in vivo and ex vivo models for the experimental study of sheep scrapie: development and perspectives. C R Biol (2002) 0.99
PrP polymorphisms tightly control sheep prion replication in cultured cells. J Virol (2003) 0.99
Overexpression of miR-30b in the developing mouse mammary gland causes a lactation defect and delays involution. PLoS One (2012) 0.99
Preeclampsia-like symptoms induced in mice by fetoplacental expression of STOX1 are reversed by aspirin treatment. Hypertension (2013) 0.98
Characterization of Schlafen-3 expression in effector and regulatory T cells. J Leukoc Biol (2009) 0.96
The C-type lectin-like receptor CLEC-1, expressed by myeloid cells and endothelial cells, is up-regulated by immunoregulatory mediators and moderates T cell activation. J Immunol (2009) 0.93
Toward a personalized treatment of Hodgkin's disease. N Engl J Med (2010) 0.91
Transcriptomic analysis brings new insight into the biological role of the prion protein during mouse embryogenesis. PLoS One (2011) 0.88
Prion protein and Shadoo are involved in overlapping embryonic pathways and trophoblastic development. PLoS One (2012) 0.87
Nitroso-redox balance and mitochondrial homeostasis are regulated by STOX1, a pre-eclampsia-associated gene. Antioxid Redox Signal (2014) 0.86
SOCS3 promotes apoptosis of mammary differentiated cells. Biochem Biophys Res Commun (2005) 0.86
Use of GRA6-derived synthetic polymorphic peptides in an immunoenzymatic assay to serotype Toxoplasma gondii in human serum samples collected from three continents. Clin Vaccine Immunol (2008) 0.86
Ubiquitous Gasp1 overexpression in mice leads mainly to a hypermuscular phenotype. BMC Genomics (2012) 0.85
Goat SRY induces testis development in XX transgenic mice. FEBS Lett (2006) 0.85
Brain transcriptional stability upon prion protein-encoding gene invalidation in zygotic or adult mouse. BMC Genomics (2010) 0.84
No effect of an elevated miR-30b level in mouse milk on its level in pup tissues. RNA Biol (2015) 0.84
Generation of Sprn-regulated reporter mice reveals gonadic spatial expression of the prion-like protein Shadoo in mice. Biochem Biophys Res Commun (2011) 0.82
Real-time RT-PCR and cDNA macroarray to study the impact of the genetic polymorphism at the alphas1-casein locus on the expression of genes in the goat mammary gland during lactation. Reprod Nutr Dev (2004) 0.81
Goat RSPO1 over-expression rescues sex-reversal in Rspo1-knockout XX mice but does not perturb testis differentiation in XY or sex-reversed XX mice. Transgenic Res (2009) 0.80
Characterisation of the potential SNARE proteins relevant to milk product release by mouse mammary epithelial cells. Eur J Cell Biol (2011) 0.80
Prnp knockdown in transgenic mice using RNA interference. Transgenic Res (2008) 0.80
Glycosylation-related gene expression profiling in the brain and spleen of scrapie-affected mouse. Glycobiology (2009) 0.80
Defining the role of cooperation in early tumor progression. J Theor Biol (2011) 0.79
Molecular basis of the synergistic production of IL-1 receptor antagonist by human neutrophils stimulated with IL-4 and IL-10. Int Immunol (2002) 0.79
High sexual risk taking and diverging trends of HIV-1 and HIV-2 in the military of Guinea Bissau. J Infect Dev Ctries (2010) 0.79
Variation for resistance to kernel infection and toxin accumulation in winter wheat infected with Fusarium graminearum. Phytopathology (2012) 0.79
Detection of Ki-ras and p53 mutations by laser capture microdissection/PCR/SSCP. Methods Mol Biol (2005) 0.78
Targeted knock-down of cellular prion protein expression in myelinating Schwann cells does not alter mouse prion pathogenesis. J Gen Virol (2013) 0.78
Expression of the prion-like protein Shadoo in the developing mouse embryo. Biochem Biophys Res Commun (2011) 0.78
A comparative study between one and two effective doses (ED95) of rocuronium for tracheal intubation. Rev Bras Anestesiol (2009) 0.78
New autoantibodies and their clinical associations in juvenile myositis - a systematic review. Acta Reumatol Port (2014) 0.78
The prion protein family: looking outside the central nervous system. Prion (2012) 0.77
Penicillin binding proteins as danger signals: meningococcal penicillin binding protein 2 activates dendritic cells through Toll-like receptor 4. PLoS One (2011) 0.77
Systems medicine in oncology. Nat Clin Pract Oncol (2008) 0.76
2011 Portuguese recommendations for the use of biological therapies in patients with psoriatic arthritis. Acta Reumatol Port (2012) 0.76
Spatial and temporal down-regulation of transgene expression using the TRSID-silencer in mice: application to Prnp. FEBS Lett (2008) 0.76
Targeted expression of the only zinc finger gene in transgenic mice is associated with impaired mammary development. Transgenic Res (2002) 0.75
Transgenesis applied to goat: current applications and ongoing research. Transgenic Res (2012) 0.75
Quantitative Trait Loci Mapping for Spike Characteristics in Hexaploid Wheat. Plant Genome (2017) 0.75
Lactoferrin at basal side of mouse mammary epithelium derives in part from stroma cells. Cell Tissue Res (2009) 0.75
Spectrum of ankylosing spondylitis in Portugal. Development of BASDAI, BASFI, BASMI and mSASSS reference centile charts. Clin Rheumatol (2011) 0.75
Analysis of melanoma-related microRNAs expression during the spontaneous regression of cutaneous melanomas in MeLiM pigs. Pigment Cell Melanoma Res (2014) 0.75
Fifty years of Laboratory Investigation: chronicle of a blossoming discipline. Lab Invest (2002) 0.75
[Acute febrile neutrophilic dermatosis - Sweet's syndrome]. Acta Reumatol Port (2009) 0.75
Consciously transfusion of blood products. Systematic review of indicative factors for blood components infusion's trigger. Rev Bras Anestesiol (2012) 0.75
[Rasburicase for tophaceus gout treatment]. Acta Reumatol Port (2009) 0.75
[Mutilans psoriatic arthritis]. Acta Reumatol Port (2009) 0.75
Portuguese recommendations for the use of biological therapies in patients with axial spondyloarthritis--December 2011 update. Acta Reumatol Port (2012) 0.75
[Tissue-specific cross-species transmission of prions]. Med Sci (Paris) (2012) 0.75
Ubiquitous expression of goat cyclin T1 in transgenic mice. Transgenic Res (2002) 0.75
PORTUGUESE RECOMMENDATIONS FOR THE USE OF BIOLOGICAL THERAPIES IN PATIENTS WITH PSORIATIC ARTHRITIS--2015 UPDATE. Acta Reumatol Port (2015) 0.75