Published in Nat Genet on October 29, 2006
A mammalian microRNA expression atlas based on small RNA library sequencing. Cell (2007) 34.03
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A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. Dev Cell (2009) 5.28
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A microRNA catalog of the developing chicken embryo identified by a deep sequencing approach. Genome Res (2008) 3.74
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Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypes. Am J Hum Genet (2007) 2.62
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MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation. Exp Cell Res (2008) 2.46
MicroRNAs (miRNAs) in neurodegenerative diseases. Brain Pathol (2008) 2.39
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High-throughput sequencing of Medicago truncatula short RNAs identifies eight new miRNA families. BMC Genomics (2008) 2.31
Deep sequencing-based discovery of the Chlamydia trachomatis transcriptome. Nucleic Acids Res (2009) 2.20
Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. Blood (2010) 2.15
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Identification and remediation of biases in the activity of RNA ligases in small-RNA deep sequencing. Nucleic Acids Res (2011) 2.01
Identification of regulatory RNAs in Bacillus subtilis. Nucleic Acids Res (2010) 1.99
An integrated approach for experimental target identification of hypoxia-induced miR-210. J Biol Chem (2009) 1.90
A three-stage genome-wide association study of general cognitive ability: hunting the small effects. Behav Genet (2010) 1.85
Structural bias in T4 RNA ligase-mediated 3'-adapter ligation. Nucleic Acids Res (2012) 1.81
Serum response factor micromanaging cardiogenesis. Curr Opin Cell Biol (2007) 1.77
Context-dependent functions of specific microRNAs in neuronal development. Neural Dev (2010) 1.74
microRNAs and muscle disorders. J Cell Sci (2009) 1.73
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Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. PLoS One (2009) 1.70
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High-resolution transcriptome maps reveal strain-specific regulatory features of multiple Campylobacter jejuni isolates. PLoS Genet (2013) 1.67
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Comprehensive survey of human brain microRNA by deep sequencing. BMC Genomics (2010) 1.59
Lowly expressed human microRNA genes evolve rapidly. Mol Biol Evol (2009) 1.58
MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates. PLoS Biol (2011) 1.57
Cortical evolution: judge the brain by its cover. Neuron (2013) 1.54
Highly sensitive and specific microRNA expression profiling using BeadArray technology. Nucleic Acids Res (2008) 1.54
The next-generation sequencing technology and application. Protein Cell (2010) 1.52
The evolution and functional diversification of animal microRNA genes. Cell Res (2008) 1.49
miR-186 is decreased in aged brain and suppresses BACE1 expression. J Neurochem (2016) 1.49
Cloning, characterization and expression analysis of porcine microRNAs. BMC Genomics (2009) 1.49
Deep sequencing of chicken microRNAs. BMC Genomics (2008) 1.48
The primary transcriptome of barley chloroplasts: numerous noncoding RNAs and the dominating role of the plastid-encoded RNA polymerase. Plant Cell (2012) 1.47
MicroRNAs of Bombyx mori identified by Solexa sequencing. BMC Genomics (2010) 1.46
Cloning, characterization, and expression of microRNAs from the Asian malaria mosquito, Anopheles stephensi. BMC Genomics (2008) 1.41
MicroRNAome of porcine pre- and postnatal development. PLoS One (2010) 1.40
Design and delivery of antisense oligonucleotides to block microRNA function in cultured Drosophila and human cells. Nat Protoc (2008) 1.38
New methods for next generation sequencing based microRNA expression profiling. BMC Genomics (2010) 1.38
Technical variables in high-throughput miRNA expression profiling: much work remains to be done. Biochim Biophys Acta (2008) 1.36
Parallel DNA pyrosequencing unveils new zebrafish microRNAs. BMC Genomics (2009) 1.36
Genome-wide transcriptional profiling reveals microRNA-correlated genes and biological processes in human lymphoblastoid cell lines. PLoS One (2009) 1.35
New perspectives on central and peripheral immune responses to acute traumatic brain injury. J Neuroinflammation (2012) 1.34
Identification of new genes in Sinorhizobium meliloti using the Genome Sequencer FLX system. BMC Microbiol (2008) 1.34
Concise review: MicroRNA expression in multipotent mesenchymal stromal cells. Stem Cells (2007) 1.32
Insect-Specific microRNA Involved in the Development of the Silkworm Bombyx mori. PLoS One (2009) 1.31
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Genome-wide identification and analysis of small RNAs originated from natural antisense transcripts in Oryza sativa. Genome Res (2008) 1.28
Small RNA class transition from siRNA/piRNA to miRNA during pre-implantation mouse development. Nucleic Acids Res (2010) 1.27
The future of genetics in psychology and psychiatry: microarrays, genome-wide association, and non-coding RNA. J Child Psychol Psychiatry (2009) 1.26
Discovery of novel microRNAs in female reproductive tract using next generation sequencing. PLoS One (2010) 1.26
Genome-wide transcriptome analysis of the plant pathogen Xanthomonas identifies sRNAs with putative virulence functions. Nucleic Acids Res (2011) 1.25
Evidence for the biogenesis of more than 1,000 novel human microRNAs. Genome Biol (2014) 1.23
Circulating cardio-enriched microRNAs are associated with long-term prognosis following myocardial infarction. BMC Cardiovasc Disord (2013) 1.22
miRNAminer: a tool for homologous microRNA gene search. BMC Bioinformatics (2008) 1.21
Repertoire of bovine miRNA and miRNA-like small regulatory RNAs expressed upon viral infection. PLoS One (2009) 1.19
High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta. BMC Genet (2010) 1.18
The transcriptional landscape of Chlamydia pneumoniae. Genome Biol (2011) 1.16
Human brain evolution: transcripts, metabolites and their regulators. Nat Rev Neurosci (2013) 1.16
Small RNA expression and strain specificity in the rat. BMC Genomics (2010) 1.16
Analysis of microRNA expression by in situ hybridization with RNA oligonucleotide probes. Methods (2007) 1.15
Computational RNomics of drosophilids. BMC Genomics (2007) 1.15
cis- and trans-Regulation of miR163 and target genes confers natural variation of secondary metabolites in two Arabidopsis species and their allopolyploids. Plant Cell (2011) 1.15
The evolution of core proteins involved in microRNA biogenesis. BMC Evol Biol (2008) 1.14
The Impact of MicroRNAs on Brain Aging and Neurodegeneration. Curr Gerontol Geriatr Res (2012) 1.14
Next-generation sequencing in aging research: emerging applications, problems, pitfalls and possible solutions. Ageing Res Rev (2009) 1.12
Genetic association and altered gene expression of mir-155 in multiple sclerosis patients. Int J Mol Sci (2011) 1.11
Promising Candidate Urinary MicroRNA Biomarkers for the Early Detection of Hepatocellular Carcinoma among High-Risk Hepatitis C Virus Egyptian Patients. J Cancer (2011) 1.09
Robust global microRNA expression profiling using next-generation sequencing technologies. Lab Invest (2014) 1.09
Cause or Effect: Misregulation of microRNA Pathways in Neurodegeneration. Front Neurosci (2012) 1.09
Small RNAs, DNA methylation and transposable elements in wheat. BMC Genomics (2010) 1.08
Interspecies regulation of microRNAs and their targets. Biochim Biophys Acta (2008) 1.08
MicroRNA regulation of the synaptic plasticity-related gene Arc. PLoS One (2012) 1.07
Discovery and characterization of medaka miRNA genes by next generation sequencing platform. BMC Genomics (2010) 1.07
The diverse functions of microRNAs in animal development and disease. Dev Cell (2006) 15.62
MicroRNA expression in zebrafish embryonic development. Science (2005) 15.52
Processing of primary microRNAs by the Microprocessor complex. Nature (2004) 14.59
Phylogenetic shadowing and computational identification of human microRNA genes. Cell (2005) 13.24
The zebrafish reference genome sequence and its relationship to the human genome. Nature (2013) 8.52
MicroRNA function in animal development. FEBS Lett (2005) 6.93
In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes. Nat Methods (2006) 6.67
MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation (2007) 6.41
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell (2007) 6.31
Progress and prospects in rat genetics: a community view. Nat Genet (2008) 6.01
Mammalian mirtron genes. Mol Cell (2007) 5.75
Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi. Curr Biol (2002) 5.66
IMGT/HLA and IMGT/MHC: sequence databases for the study of the major histocompatibility complex. Nucleic Acids Res (2003) 5.64
Secondary siRNAs result from unprimed RNA synthesis and form a distinct class. Science (2006) 5.49
Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. Genome Res (2006) 5.23
Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol (2003) 5.07
The microRNA-producing enzyme Dicer1 is essential for zebrafish development. Nat Genet (2003) 4.97
RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain. RNA (2005) 4.91
Stem-cell-based therapy and lessons from the heart. Nature (2008) 4.54
Concern Substrate requirements for let-7 function in the developing zebrafish embryo. Nucleic Acids Res (2004) 4.50
Limitations and possibilities of small RNA digital gene expression profiling. Nat Methods (2009) 4.34
Approaches to microRNA discovery. Nat Genet (2006) 4.32
Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi. Nature (2003) 4.09
Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell (2013) 3.97
Disclosure of individual genetic data to research participants: the debate reconsidered. Trends Genet (2010) 3.83
A micrococcal nuclease homologue in RNAi effector complexes. Nature (2003) 3.67
Efficient target-selected mutagenesis in zebrafish. Genome Res (2003) 3.61
A systematic genome-wide analysis of zebrafish protein-coding gene function. Nature (2013) 3.52
Mapping determinants of gene expression plasticity by genetical genomics in C. elegans. PLoS Genet (2006) 3.39
Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries. Nucleic Acids Res (2010) 3.23
Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport. Genes Dev (2004) 3.21
MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system. Genome Biol (2007) 3.05
Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development. PLoS Biol (2007) 3.04
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells. Mol Cell Biol (2008) 3.02
SNP and haplotype mapping for genetic analysis in the rat. Nat Genet (2008) 2.96
Great ape genetic diversity and population history. Nature (2013) 2.95
The Wnt/beta-catenin pathway regulates cardiac valve formation. Nature (2003) 2.89
Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation. Proc Natl Acad Sci U S A (2004) 2.89
A fine-scale chimpanzee genetic map from population sequencing. Science (2012) 2.83
Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Genes Dev (2003) 2.76
Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanisms. Cell Rep (2012) 2.67
Target-selected inactivation of the zebrafish rag1 gene. Science (2002) 2.60
Cloning and expression of new microRNAs from zebrafish. Nucleic Acids Res (2006) 2.58
MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques. PLoS One (2009) 2.49
Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell (2012) 2.45
Differences in vertebrate microRNA expression. Proc Natl Acad Sci U S A (2006) 2.45
Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline. Hum Mol Genet (2011) 2.43
Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics. Nat Biotechnol (2003) 2.37
Ethical, legal, and counseling challenges surrounding the return of genetic results in oncology. J Clin Oncol (2013) 2.36
Multiple instances of ancient balancing selection shared between humans and chimpanzees. Science (2013) 2.32
Gene expression: long-term gene silencing by RNAi. Nature (2006) 2.27
Genetic variation in the zebrafish. Genome Res (2006) 2.22
Distribution and functional impact of DNA copy number variation in the rat. Nat Genet (2008) 2.20
Camels and zebrafish, viruses and cancer: a microRNA update. Hum Mol Genet (2005) 2.18
Dicers at RISC; the mechanism of RNAi. Cell (2004) 2.14
Characterization of Sleeping Beauty transposition and its application to genetic screening in mice. Mol Cell Biol (2003) 2.13
Modified vaccinia virus Ankara protects macaques against respiratory challenge with monkeypox virus. J Virol (2005) 2.11
Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer. Genome Biol (2011) 2.11
The genetics of RNA silencing. Annu Rev Genet (2002) 2.10
Homologous gene targeting in Caenorhabditis elegans by biolistic transformation. Nucleic Acids Res (2004) 2.06
C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging. PLoS Genet (2008) 2.03
TGF-beta1 induces efficient differentiation of human cardiomyocyte progenitor cells into functional cardiomyocytes in vitro. Stem Cell Res (2008) 1.98
Mouse microRNA profiles determined with a new and sensitive cloning method. Nucleic Acids Res (2006) 1.94
Chromatin and RNAi factors protect the C. elegans germline against repetitive sequences. Genes Dev (2005) 1.94
A genome-wide screen identifies 27 genes involved in transposon silencing in C. elegans. Curr Biol (2003) 1.92
RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs. Science (2002) 1.91
PPW-1, a PAZ/PIWI protein required for efficient germline RNAi, is defective in a natural isolate of C. elegans. Curr Biol (2002) 1.91
Structural features of small RNA precursors determine Argonaute loading in Caenorhabditis elegans. Nat Struct Mol Biol (2007) 1.84
LPIN2 is associated with type 2 diabetes, glucose metabolism, and body composition. Diabetes (2007) 1.83
Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans. Curr Biol (2008) 1.80
Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples. Nat Methods (2010) 1.77
Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway. Genes Dev (2007) 1.74
Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology. Cardiovasc Res (2013) 1.72
Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes. Genome Biol (2014) 1.66
Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment. Clin Cancer Res (2011) 1.64
Repertoire and evolution of miRNA genes in four divergent nematode species. Genome Res (2009) 1.64
Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis. Pharmacogenet Genomics (2006) 1.60
Genes required for systemic RNA interference in Caenorhabditis elegans. Curr Biol (2004) 1.59
CONREAL: conserved regulatory elements anchored alignment algorithm for identification of transcription factor binding sites by phylogenetic footprinting. Genome Res (2003) 1.57
Worms taste bitter: ASH neurons, QUI-1, GPA-3 and ODR-3 mediate quinine avoidance in Caenorhabditis elegans. EMBO J (2004) 1.56
Zebrafish as a cancer model. Mol Cancer Res (2008) 1.55
Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat. Cell (2013) 1.53
Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium. Cardiovasc Res (2009) 1.52
Dominant missense mutations in ABCC9 cause Cantú syndrome. Nat Genet (2012) 1.50
Melanocortin receptor 4 deficiency affects body weight regulation, grooming behavior, and substrate preference in the rat. Obesity (Silver Spring) (2011) 1.50
RNAi protects the Caenorhabditis elegans germline against transposition. Trends Genet (2004) 1.48
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Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis. Ann Neurol (2011) 1.45