Published in Cardiovasc Res on April 07, 2009
Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets. Nat Rev Drug Discov (2010) 2.90
Cigarette smoke-induced mitochondrial fragmentation and dysfunction in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2014) 1.72
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Redox signaling in cardiovascular health and disease. Free Radic Biol Med (2013) 1.16
Effects of interventions on oxidative stress and inflammation of cardiovascular diseases. World J Cardiol (2011) 1.11
Impaired transcriptional activity of Nrf2 in age-related myocardial oxidative stress is reversible by moderate exercise training. PLoS One (2012) 1.10
Acute decreases in proteasome pathway activity after inhalation of fresh diesel exhaust or secondary organic aerosol. Environ Health Perspect (2010) 0.97
Redox signaling pathways involved in neuronal ischemic preconditioning. Curr Neuropharmacol (2012) 0.95
The role of Nrf2-mediated pathway in cardiac remodeling and heart failure. Oxid Med Cell Longev (2014) 0.90
Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration. Mol Aspects Med (2012) 0.89
Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2. Nat Commun (2015) 0.86
Preventive and therapeutic effects of MG132 by activating Nrf2-ARE signaling pathway on oxidative stress-induced cardiovascular and renal injury. Oxid Med Cell Longev (2013) 0.86
Bortezomib, a proteasome inhibitor, attenuates angiotensin II-induced hypertension and aortic remodeling in rats. PLoS One (2013) 0.85
Redox Mechanism of Reactive Oxygen Species in Exercise. Front Physiol (2016) 0.84
Alteration of peripheral blood monocyte gene expression in humans following diesel exhaust inhalation. Inhal Toxicol (2012) 0.84
Neocortex and allocortex respond differentially to cellular stress in vitro and aging in vivo. PLoS One (2013) 0.84
The role of ubiquitination and sumoylation in diabetic nephropathy. Biomed Res Int (2014) 0.83
Antioxidant effects of the ethanol extract from flower of Camellia japonica via scavenging of reactive oxygen species and induction of antioxidant enzymes. Int J Mol Sci (2011) 0.83
Knockdown of Nrf2 inhibits the angiogenesis of rat cardiac micro-vascular endothelial cells under hypoxic conditions. Int J Biol Sci (2013) 0.83
Hydrogen Sulfide and Cellular Redox Homeostasis. Oxid Med Cell Longev (2016) 0.82
Attenuation of hyperoxia-induced lung injury in rats by adrenomedullin. Inflammation (2012) 0.82
Paeonol and danshensu combination attenuates apoptosis in myocardial infarcted rats by inhibiting oxidative stress: Roles of Nrf2/HO-1 and PI3K/Akt pathway. Sci Rep (2016) 0.81
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Prometheus's heart: what lies beneath. J Cell Mol Med (2012) 0.80
Role of Nrf2, HO-1 and GSH in Neuroblastoma Cell Resistance to Bortezomib. PLoS One (2016) 0.80
Sulforaphane-induced transcription of thioredoxin reductase in lens: possible significance against cataract formation. Clin Ophthalmol (2013) 0.79
Alteration of serum lipid profile, SRB1 loss, and impaired Nrf2 activation in CDKL5 disorder. Free Radic Biol Med (2015) 0.79
Signaling pathways leading to ischemic mitochondrial neuroprotection. J Bioenerg Biomembr (2014) 0.79
Histidine Prevents Cu-Induced Oxidative Stress and the Associated Decreases in mRNA from Encoding Tight Junction Proteins in the Intestine of Grass Carp (Ctenopharyngodon idella). PLoS One (2016) 0.78
Unfolded protein response is activated in aged retinas. Neurosci Lett (2015) 0.78
Dysfunction of the ubiquitin-proteasome system in atherosclerotic cardiovascular disease. Am J Cardiovasc Dis (2015) 0.77
Overdosage of methylparaben induces cellular senescence in vitro and in vivo. J Invest Dermatol (2014) 0.77
MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 cells in vitro by regulating LDLR and PCSK9 expression. Acta Pharmacol Sin (2014) 0.76
AAV-Nrf2 Promotes Protection and Recovery in Animal Models of Oxidative Stress. Mol Ther (2017) 0.75
Oregano Essential Oil Induces SOD1 and GSH Expression through Nrf2 Activation and Alleviates Hydrogen Peroxide-Induced Oxidative Damage in IPEC-J2 Cells. Oxid Med Cell Longev (2016) 0.75
CXCL12 protects pancreatic β-cells from oxidative stress by a Nrf2-induced increase in catalase expression and activity. Proc Jpn Acad Ser B Phys Biol Sci (2016) 0.75
Involvement of Heme Oxygenase-1 in Orexin-A-induced Angiogenesis in Vascular Endothelial Cells. Korean J Physiol Pharmacol (2015) 0.75
Functionalized Fullerene Increases NF-κB Activity and Blocks Genotoxic Effect of Oxidative Stress in Serum-Starving Human Embryo Lung Diploid Fibroblasts. Oxid Med Cell Longev (2016) 0.75
Proteasome inhibitors attenuated cholesterol-induced cardiac hypertrophy in H9c2 cells. BMB Rep (2016) 0.75
Molecular Evolution of the Nuclear Factor (Erythroid-Derived 2)-Like 2 Gene Nrf2 in Old World Fruit Bats (Chiroptera: Pteropodidae). PLoS One (2016) 0.75
PFOS induces adipogenesis and glucose uptake in association with activation of Nrf2 signaling pathway. Toxicol Appl Pharmacol (2015) 0.75
Prevention of Streptozotocin-Induced Diabetic Nephropathy by MG132: Possible Roles of Nrf2 and IκB. Oxid Med Cell Longev (2017) 0.75
HnRNP L stimulates splicing of the eNOS gene by binding to variable-length CA repeats. Nat Struct Biol (2003) 3.22
Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: the telemedical interventional monitoring in heart failure study. Circulation (2011) 2.87
Addition of milk prevents vascular protective effects of tea. Eur Heart J (2007) 2.80
Noninvasive detection of coronary artery stenoses with multislice computed tomography or magnetic resonance imaging. Ann Intern Med (2006) 2.04
Percutaneous transfemoral management of severe secondary tricuspid regurgitation with Edwards Sapien XT bioprosthesis: first-in-man experience. J Am Coll Cardiol (2013) 2.02
Molecular targets of tea polyphenols in the cardiovascular system. Cardiovasc Res (2006) 1.92
Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats. Hypertension (2005) 1.89
Inhibition of proteasome activity induces concerted expression of proteasome genes and de novo formation of Mammalian proteasomes. J Biol Chem (2003) 1.87
Ubiquitin-proteasome pathway as a new target for the prevention of restenosis. Circulation (2002) 1.75
Female-specific aspects in the pharmacotherapy of chronic cardiovascular diseases. Eur Heart J (2005) 1.71
Computed tomography angiography and myocardial computed tomography perfusion in patients with coronary stents: prospective intraindividual comparison with conventional coronary angiography. J Am Coll Cardiol (2013) 1.67
Myocardial function in older male amateur marathon runners: assessment by tissue Doppler echocardiography, speckle tracking, and cardiac biomarkers. J Am Soc Echocardiogr (2009) 1.63
Automatic pressure titration with APAP is as effective as manual titration with CPAP in patients with obstructive sleep apnea. Respiration (2007) 1.57
Vascular-protective effects of high-density lipoprotein include the downregulation of the angiotensin II type 1 receptor. Hypertension (2009) 1.54
Functional significance of a hereditary adenine insertion variant in the 5'-UTR of the endothelin-1 gene. Pharmacogenetics (2003) 1.51
Comparison of non-gated vs. electrocardiogram-gated 64-detector-row computed tomography for integrated electroanatomic mapping in patients undergoing pulmonary vein isolation. Europace (2010) 1.50
Potent anti-inflammatory effects of low-dose proteasome inhibition in the vascular system. J Mol Med (Berl) (2009) 1.49
Humoral anti-proteasomal autoimmunity in dilated cardiomyopathy. Basic Res Cardiol (2010) 1.47
Influence of sex on outcome following transcatheter aortic valve implantation (TAVI): systematic review and meta-analysis. J Interv Cardiol (2014) 1.42
Renal sympathetic denervation: early impact on ambulatory resistant hypertension. J Clin Hypertens (Greenwich) (2014) 1.40
Intravenous recombinant human relaxin in compensated heart failure: a safety, tolerability, and pharmacodynamic trial. J Card Fail (2009) 1.26
Suppression of cardiomyocyte hypertrophy by inhibition of the ubiquitin-proteasome system. Hypertension (2007) 1.26
Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage. Circulation (2005) 1.23
The role of tea and tea flavonoids in cardiovascular health. Mol Nutr Food Res (2006) 1.22
Right ventricular function assessed by two-dimensional strain and tissue Doppler echocardiography in patients with pulmonary arterial hypertension and effect of vasodilator therapy. Am J Cardiol (2006) 1.20
Contrast-enhanced MR imaging of atherosclerosis using citrate-coated superparamagnetic iron oxide nanoparticles: calcifying microvesicles as imaging target for plaque characterization. Int J Nanomedicine (2013) 1.17
Proteasome inhibitors: poisons and remedies. Med Res Rev (2008) 1.16
Long-term up-regulation of eNOS and improvement of endothelial function by inhibition of the ubiquitin-proteasome pathway. FASEB J (2004) 1.11
Nontoxic proteasome inhibition activates a protective antioxidant defense response in endothelial cells. Free Radic Biol Med (2006) 1.10
The tea flavonoid epigallocatechin-3-gallate reduces cytokine-induced VCAM-1 expression and monocyte adhesion to endothelial cells. Biochem Biophys Res Commun (2004) 1.08
Downregulation of matrix metalloproteinases and collagens and suppression of cardiac fibrosis by inhibition of the proteasome. Hypertension (2004) 1.08
Inhibition of the ubiquitin-proteasome pathway induces differential heat-shock protein response in cardiomyocytes and renders early cardiac protection. Biochem Biophys Res Commun (2002) 1.08
Potential role of autoantibodies belonging to the immunoglobulin G-3 subclass in cardiac dysfunction among patients with dilated cardiomyopathy. Circulation (2002) 1.08
Telemedical Interventional Monitoring in Heart Failure (TIM-HF), a randomized, controlled intervention trial investigating the impact of telemedicine on mortality in ambulatory patients with heart failure: study design. Eur J Heart Fail (2010) 1.07
Multiple cardiac proteasome subtypes differ in their susceptibility to proteasome inhibitors. Cardiovasc Res (2009) 1.07
Acute cigarette smoke exposure impairs proteasome function in the lung. Am J Physiol Lung Cell Mol Physiol (2012) 1.04
Relaxin-a pleiotropic hormone and its emerging role for experimental and clinical therapeutics. Pharmacol Ther (2006) 1.02
Removal of cardiodepressant antibodies in dilated cardiomyopathy by immunoadsorption. J Am Coll Cardiol (2002) 0.99
The ubiquitin-proteasome pathway and endothelial (dys)function. Cardiovasc Res (2009) 0.99
Potential role of humoral immunity in cardiac dysfunction of patients suffering from dilated cardiomyopathy. J Am Coll Cardiol (2004) 0.99
Electron beam tomography of interpulmonary saddle embolism: extent and vascular distribution. J Comput Assist Tomogr (2002) 0.99
Role of immunoglobulin G3 subclass in dilated cardiomyopathy: results from protein A immunoadsorption. Am Heart J (2005) 0.98
NT-ProBNP in acute heart failure: correlation with invasively measured hemodynamic parameters during recompensation. J Card Fail (2005) 0.98
Hemodynamic improvement and removal of autoantibodies against beta1-adrenergic receptor by immunoadsorption therapy in dilated cardiomyopathy. J Autoimmun (2003) 0.98
Green and black tea are equally potent stimuli of NO production and vasodilation: new insights into tea ingredients involved. Basic Res Cardiol (2008) 0.98
Apical tissue tracking echocardiography for characterization of regional left ventricular function: comparison with magnetic resonance imaging in patients after myocardial infarction. J Am Soc Echocardiogr (2003) 0.98
Noninvasive monitoring of myocardial function after surgical and cytostatic therapy in a peritoneal metastasis rat model: assessment with tissue Doppler and non-Doppler 2D strain echocardiography. Cardiovasc Ultrasound (2007) 0.97
p38 mitogen-activated protein kinase inhibition ameliorates angiotensin II-induced target organ damage. Hypertension (2007) 0.97
Protection of vascular cells from oxidative stress by proteasome inhibition depends on Nrf2. Cardiovasc Res (2009) 0.96
Evaluation of longitudinal and radial two-dimensional strain imaging versus Doppler tissue echocardiography in predicting long-term response to cardiac resynchronization therapy. J Am Soc Echocardiogr (2007) 0.96
Immunoadsorption in idiopathic dilated cardiomyopathy, a 3-year follow-up. Int J Cardiol (2004) 0.96
Current diagnostic concepts to detect coronary artery disease in women. Eur Heart J (2008) 0.95