Published in Am J Physiol Lung Cell Mol Physiol on September 07, 2012
Cigarette smoke-induced mitochondrial fragmentation and dysfunction in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2014) 1.72
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. J Clin Invest (2013) 1.29
Mitochondria in lung diseases. Expert Rev Respir Med (2013) 0.93
Cigarette smoke exposure exacerbates lung inflammation and compromises immunity to bacterial infection. J Immunol (2014) 0.91
Airway Exposure to E-Cigarette Vapors Impairs Autophagy and Induces Aggresome Formation. Antioxid Redox Signal (2015) 0.89
The emerging role of the ubiquitin proteasome in pulmonary biology and disease. Am J Respir Crit Care Med (2013) 0.87
Regulation of immunoproteasome function in the lung. Sci Rep (2015) 0.85
Lost after translation: insights from pulmonary surfactant for understanding the role of alveolar epithelial dysfunction and cellular quality control in fibrotic lung disease. Am J Physiol Lung Cell Mol Physiol (2015) 0.83
Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking. Sci Rep (2016) 0.80
The Unfolded Protein Response in Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc (2016) 0.79
Proteostasis in pediatric pulmonary pathology. Mol Cell Pediatr (2014) 0.78
Decreased proteasomal function accelerates cigarette smoke-induced pulmonary emphysema in mice. Lab Invest (2015) 0.77
Genes related to emphysema are enriched for ubiquitination pathways. BMC Pulm Med (2014) 0.77
Protein oxidation and degradation caused by particulate matter. Sci Rep (2016) 0.77
The Role of Mitochondria and Oxidative/Antioxidative Imbalance in Pathobiology of Chronic Obstructive Pulmonary Disease. Oxid Med Cell Longev (2016) 0.76
Proteasome function is not impaired in healthy aging of the lung. Aging (Albany NY) (2015) 0.75
Augmenting autophagy for prognosis based intervention of COPD-pathophysiology. Respir Res (2017) 0.75
Inhibition of Proteasome Activity Induces Formation of Alternative Proteasome Complexes. J Biol Chem (2016) 0.75
Associations of autophagy with lung diffusion capacity and oxygen saturation in severe COPD: effects of particulate air pollution. Int J Chron Obstruct Pulmon Dis (2016) 0.75
Cigarette smoke induces proteasomal-mediated degradation of DNA methyltransferases and methyl CpG-/CpG domain-binding proteins in embryonic orofacial cells. Reprod Toxicol (2015) 0.75
Cigarette smoke destabilizes NLRP3 protein by promoting its ubiquitination. Respir Res (2017) 0.75
Is there a therapeutic role for selenium in alpha-1 antitrypsin deficiency? Nutrients (2013) 0.75
Cigarette smoke induced autophagy-impairment regulates AMD pathogenesis mechanisms in ARPE-19 cells. PLoS One (2017) 0.75
Cellular and molecular pathobiology of pulmonary arterial hypertension. J Am Coll Cardiol (2004) 5.79
WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. J Clin Invest (2009) 3.33
Inhibition and role of let-7d in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2010) 3.02
Functional Wnt signaling is increased in idiopathic pulmonary fibrosis. PLoS One (2008) 2.94
Genetics and genomics of pulmonary arterial hypertension. J Am Coll Cardiol (2009) 2.31
Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension. Hum Mutat (2006) 2.30
Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA. Am J Physiol Lung Cell Mol Physiol (2006) 2.29
Retracted CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation. Nat Med (2010) 2.17
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem (2009) 2.12
Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury. J Clin Invest (2009) 1.96
Activation of the WNT/β-catenin pathway attenuates experimental emphysema. Am J Respir Crit Care Med (2010) 1.94
WNT signaling in lung disease: a failure or a regeneration signal? Am J Respir Cell Mol Biol (2009) 1.90
Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats. Hypertension (2005) 1.89
Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease. Thorax (2012) 1.88
The impact of TGF-β on lung fibrosis: from targeting to biomarkers. Proc Am Thorac Soc (2012) 1.74
Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol (2006) 1.71
Conditional overexpression of bioactive transforming growth factor-beta1 in neonatal mouse lung: a new model for bronchopulmonary dysplasia? Am J Respir Cell Mol Biol (2004) 1.67
Emphysema diagnosis using X-ray dark-field imaging at a laser-driven compact synchrotron light source. Proc Natl Acad Sci U S A (2012) 1.62
Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J Immunol (2008) 1.56
Caveolin-1 facilitates mechanosensitive protein kinase B (Akt) signaling in vitro and in vivo. Circ Res (2005) 1.55
Genetic basis of pulmonary arterial hypertension: current understanding and future directions. J Am Coll Cardiol (2004) 1.53
Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention. Thorax (2010) 1.52
Potent anti-inflammatory effects of low-dose proteasome inhibition in the vascular system. J Mol Med (Berl) (2009) 1.49
New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis. Lancet (2012) 1.47
Investigation of the antifibrotic effect of IFN-gamma on fibroblasts in a cell culture model of Peyronie's disease. Eur Urol (2007) 1.47
Comparison of two devices and two breathing patterns for exhaled breath condensate sampling. PLoS One (2011) 1.45
Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension. Arterioscler Thromb Vasc Biol (2007) 1.43
Leukocytes induce epithelial to mesenchymal transition after unilateral ureteral obstruction in neonatal mice. Am J Pathol (2007) 1.39
Loss of RAGE in pulmonary fibrosis: molecular relations to functional changes in pulmonary cell types. Am J Respir Cell Mol Biol (2008) 1.31
MUC5AC and MUC5B mucins increase in cystic fibrosis airway secretions during pulmonary exacerbation. Am J Respir Crit Care Med (2007) 1.30
Chronic lung disease in the preterm infant. Lessons learned from animal models. Am J Respir Cell Mol Biol (2014) 1.28
Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for proteasome inhibitor-mediated cardioprotection. Cardiovasc Res (2009) 1.26
From arginine methylation to ADMA: a novel mechanism with therapeutic potential in chronic lung diseases. BMC Pulm Med (2009) 1.24
Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage. Circulation (2005) 1.23
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. Dev Dyn (2008) 1.15
The angiotensin II receptor 2 is expressed and mediates angiotensin II signaling in lung fibrosis. Am J Respir Cell Mol Biol (2007) 1.15
Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2008) 1.15
Transforming growth factor-beta signaling across ages: from distorted lung development to chronic obstructive pulmonary disease. Proc Am Thorac Soc (2009) 1.14
Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3. Int J Biochem Cell Biol (2007) 1.11
Long-term up-regulation of eNOS and improvement of endothelial function by inhibition of the ubiquitin-proteasome pathway. FASEB J (2004) 1.11
Epigenetic regulation in murine offspring as a novel mechanism for transmaternal asthma protection induced by microbes. J Allergy Clin Immunol (2011) 1.10
Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice. J Clin Invest (2011) 1.10
Serine proteases degrade airway mucins in cystic fibrosis. Infect Immun (2011) 1.09
Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter. J Biol Chem (2010) 1.09
Innovations in phenotyping of mouse models in the German Mouse Clinic. Mamm Genome (2012) 1.09
Transgelin is a direct target of TGF-beta/Smad3-dependent epithelial cell migration in lung fibrosis. FASEB J (2008) 1.09
The tea flavonoid epigallocatechin-3-gallate reduces cytokine-induced VCAM-1 expression and monocyte adhesion to endothelial cells. Biochem Biophys Res Commun (2004) 1.08
Inhibition of the ubiquitin-proteasome pathway induces differential heat-shock protein response in cardiomyocytes and renders early cardiac protection. Biochem Biophys Res Commun (2002) 1.08
Gli1 mediates lung cancer cell proliferation and Sonic Hedgehog-dependent mesenchymal cell activation. PLoS One (2013) 1.08
Functional role and species-specific contribution of arginases in pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2007) 1.07
Multiple cardiac proteasome subtypes differ in their susceptibility to proteasome inhibitors. Cardiovasc Res (2009) 1.07
Alveolar fluid clearance in acute lung injury: what have we learned from animal models and clinical studies? Intensive Care Med (2007) 1.06
Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis. Am J Respir Crit Care Med (2008) 1.06
Pulmonary emphysema diagnosis with a preclinical small-animal X-ray dark-field scatter-contrast scanner. Radiology (2013) 1.05
Receptor for activated C-kinase 1, a novel interaction partner of type II bone morphogenetic protein receptor, regulates smooth muscle cell proliferation in pulmonary arterial hypertension. Circulation (2007) 1.04
Tissue remodelling in chronic bronchial diseases: from the epithelial to mesenchymal phenotype. Eur Respir Rev (2014) 1.04
Fhl-1, a new key protein in pulmonary hypertension. Circulation (2008) 1.03
Transforming growth factor-beta-dependent growth inhibition in primary vascular smooth muscle cells is p38-dependent. J Pharmacol Exp Ther (2005) 1.03
TGF-beta signaling in COPD: deciphering genetic and cellular susceptibilities for future therapeutic regimen. Swiss Med Wkly (2009) 1.02
High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells. PLoS One (2011) 1.02
TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury. Proc Natl Acad Sci U S A (2013) 1.01
Regulation of TGF-beta ligand and receptor expression in neonatal rat lungs exposed to chronic hypoxia. J Appl Physiol (1985) (2002) 1.00
Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension. Am J Respir Crit Care Med (2010) 1.00
Lysyl oxidase activity is dysregulated during impaired alveolarization of mouse and human lungs. Am J Respir Crit Care Med (2009) 1.00
p38 mitogen-activated protein kinase inhibition ameliorates angiotensin II-induced target organ damage. Hypertension (2007) 0.97
Protection of vascular cells from oxidative stress by proteasome inhibition depends on Nrf2. Cardiovasc Res (2009) 0.96
Palifermin induces alveolar maintenance programs in emphysematous mice. Am J Respir Crit Care Med (2009) 0.95
High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner. J Biol Chem (2013) 0.95
Blue journal conference. Aging and susceptibility to lung disease. Am J Respir Crit Care Med (2015) 0.94
Inflammatory and oxidative stress responses of an alveolar epithelial cell line to airborne zinc oxide nanoparticles at the air-liquid interface: a comparison with conventional, submerged cell-culture conditions. Biomed Res Int (2013) 0.94
The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis. Sci Transl Med (2011) 0.94
The composition of cigarette smoke determines inflammatory cell recruitment to the lung in COPD mouse models. Clin Sci (Lond) (2014) 0.93
Paired immunoglobulin-like receptor-B inhibits pulmonary fibrosis by suppressing profibrogenic properties of alveolar macrophages. Am J Respir Cell Mol Biol (2013) 0.93
Differential expression of matrix metalloproteinases and their inhibitors in human and mouse lung development. Thromb Haemost (2005) 0.93
Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases. Am J Respir Cell Mol Biol (2006) 0.92
The chitinase-like protein YKL-40 modulates cystic fibrosis lung disease. PLoS One (2011) 0.92
Overexpression of HSP-72 confers cytoprotection in experimental peritoneal dialysis. Kidney Int (2004) 0.92
Markers of instability in high-risk carotid plaques are reduced by statins. J Vasc Surg (2008) 0.91
Comprehensive proteomic and transcriptomic analysis reveals early induction of a protective anti-oxidative stress response by low-dose proteasome inhibition. Proteomics (2009) 0.89
Cigarette smoke-induced disruption of bronchial epithelial tight junctions is prevented by transforming growth factor-β. Am J Respir Cell Mol Biol (2014) 0.89
Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis. FASEB J (2011) 0.89
Zyxin is a transforming growth factor-β (TGF-β)/Smad3 target gene that regulates lung cancer cell motility via integrin α5β1. J Biol Chem (2012) 0.89
Cardiac gene expression profile in rats with terminal heart failure and cachexia. Physiol Genomics (2004) 0.88
Diagnosing and mapping pulmonary emphysema on X-ray projection images: incremental value of grating-based X-ray dark-field imaging. PLoS One (2013) 0.88
Ongoing coxsackievirus myocarditis is associated with increased formation and activity of myocardial immunoproteasomes. Am J Pathol (2006) 0.88
Plasminogen activator inhibitor type 1 inhibits smooth muscle cell proliferation in pulmonary arterial hypertension. Int J Biochem Cell Biol (2008) 0.87
BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension. Am J Pathol (2012) 0.87
Upregulation of mRNA expression of MCP-1 by TGF-beta1 in fibroblast cells from Peyronie's disease. World J Urol (2008) 0.87
Low-dose renin inhibitor and low-dose AT(1)-receptor blocker therapy ameliorate target-organ damage in rats harbouring human renin and angiotensinogen genes. J Renin Angiotensin Aldosterone Syst (2007) 0.86
Transcriptional and post-transcriptional regulation of transforming growth factor beta type II receptor expression in osteoblasts. Gene (2002) 0.86
Alterations in the transforming growth factor (TGF)-beta pathway as a potential factor in the pathogenesis of Peyronie's disease. Eur Urol (2006) 0.86
Improved diagnosis of pulmonary emphysema using in vivo dark-field radiography. Invest Radiol (2014) 0.86