Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2.

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Published in Nat Commun on May 13, 2015

Authors

Karen F S Bell1, Bashayer Al-Mubarak1, Marc-André Martel1, Sean McKay1, Nicola Wheelan1, Philip Hasel1, Nóra M Márkus1, Paul Baxter1, Ruth F Deighton1, Andrea Serio2, Bilada Bilican2, Sudhir Chowdhry3, Paul J Meakin3, Michael L J Ashford3, David J A Wyllie1, Robert H Scannevin4, Siddharthan Chandran2, John D Hayes3, Giles E Hardingham1

Author Affiliations

1: Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.
2: MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4SB, UK.
3: Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
4: Biogen Idec, 14 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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