Published in Trends Immunol on April 08, 2009
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Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor. Mol Cell Proteomics (2010) 0.92
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The Split Virus Influenza Vaccine rapidly activates immune cells through Fcγ receptors. Vaccine (2014) 0.88
Temporal regulation of rapamycin on memory CTL programming by IL-12. PLoS One (2011) 0.88
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Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune-deficient mice. Aging Cell (2015) 0.86
Mechanistic target of rapamycin inhibition extends cellular lifespan in dendritic cells by preserving mitochondrial function. J Immunol (2014) 0.85
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Hypoxic culture conditions enhance the generation of regulatory T cells. Immunology (2015) 0.84
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mTORC1-S6K activation by endotoxin contributes to cytokine up-regulation and early lethality in animals. PLoS One (2010) 0.82
Inhibition of mTOR reduces anal carcinogenesis in transgenic mouse model. PLoS One (2013) 0.82
Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis. Mol Autism (2014) 0.82
The second-generation mTOR kinase inhibitor INK128 exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW 264.7 cells. Inflammation (2014) 0.82
Lumen LPS inhibits HCO3(-) absorption in the medullary thick ascending limb through TLR4-PI3K-Akt-mTOR-dependent inhibition of basolateral Na+/H+ exchange. Am J Physiol Renal Physiol (2013) 0.81
Mammalian target of rapamycin inhibition in macrophages of asymptomatic HIV+ persons reverses the decrease in TLR-4-mediated TNF-α release through prolongation of MAPK pathway activation. J Immunol (2011) 0.81
Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations. PLoS Genet (2010) 0.81
The battle over mTOR: an emerging theatre in host-pathogen immunity. PLoS Pathog (2012) 0.81
Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo. Cell Death Dis (2016) 0.80
Rapamycin augments human DC IL-12p70 and IL-27 secretion to promote allogeneic Type 1 polarization modulated by NK cells. Am J Transplant (2013) 0.80
Effect of dietary glutamine on growth performance, non-specific immunity, expression of cytokine genes, phosphorylation of target of rapamycin (TOR), and anti-oxidative system in spleen and head kidney of Jian carp (Cyprinus carpio var. Jian). Fish Physiol Biochem (2015) 0.80
Phosphatase and tensin homolog (PTEN) in antigen-presenting cells controls Th17-mediated autoimmune arthritis. Arthritis Res Ther (2015) 0.80
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Plasma amino acids imbalance in cirrhotic patients disturbs the tricarboxylic acid cycle of dendritic cell. Sci Rep (2013) 0.78
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Rapamycin protects kidney against ischemia reperfusion injury through recruitment of NKT cells. J Transl Med (2014) 0.76
Pasteurella multocida toxin- induced osteoclastogenesis requires mTOR activation. Cell Commun Signal (2015) 0.76
Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages. Sci Rep (2016) 0.76
Modulation of Human Peripheral Blood Mononuclear Cell Signaling by Medicinal Cannabinoids. Front Mol Neurosci (2017) 0.75
Cord Blood Cells Responses to IL2, IL7 and IL15 Cytokines for mTOR Expression. Adv Pharm Bull (2017) 0.75
Peroxisome proliferator-activated receptor-γ agonist inhibits the mammalian target of rapamycin signaling pathway and has a protective effect in a rat model of status epilepticus. Mol Med Rep (2015) 0.75
mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis. Nat Commun (2017) 0.75
Dysregulation of the (immuno)proteasome pathway in malformations of cortical development. J Neuroinflammation (2016) 0.75
TSC1 controls IL-1β expression in macrophages via mTORC1-dependent C/EBPβ pathway. Cell Mol Immunol (2015) 0.75
Immunosuppressive potency of mechanistic target of rapamycin inhibitors in solid-organ transplantation. World J Transplant (2016) 0.75
Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling. EXCLI J (2015) 0.75
Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells. J Cell Physiol (2017) 0.75
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Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance. Diabetes (2010) 1.44
Early basal insulin therapy decreases new-onset diabetes after renal transplantation. J Am Soc Nephrol (2012) 1.44
A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation. J Immunol (2010) 1.42
Polyunsaturated fatty acids block dendritic cell activation and function independently of NF-kappaB activation. J Biol Chem (2005) 1.35
Serum amyloid A in uremic HDL promotes inflammation. J Am Soc Nephrol (2012) 1.27
Liver X receptors regulate dendritic cell phenotype and function through blocked induction of the actin-bundling protein fascin. Blood (2007) 1.15
Significance of interdialytic weight gain versus chronic volume overload: consensus opinion. Am J Nephrol (2013) 1.14
Disruption of the interaction of T cells with antigen-presenting cells by the active leflunomide metabolite teriflunomide: involvement of impaired integrin activation and immunologic synapse formation. Arthritis Rheum (2005) 1.12
Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells. Blood (2011) 1.06
Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitor-based immunosuppressive therapy in de novo renal transplant recipients. Transplantation (2012) 1.01
Effect of the proteasome inhibitor bortezomib on humoral immunity in two presensitized renal transplant candidates. Transplantation (2010) 0.99
Glucose metabolism after renal transplantation. Diabetes Care (2013) 0.99
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Apoptotic cell-free DNA promotes inflammation in haemodialysis patients. Nephrol Dial Transplant (2011) 0.97
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Selective inhibition of T cell activation via CD147 through novel modulation of lipid rafts. J Immunol (2003) 0.90
Suppression of T cell signaling by polyunsaturated fatty acids: selectivity in inhibition of mitogen-activated protein kinase and nuclear factor activation. J Immunol (2003) 0.90
Comment on: Chakkera et al. Can new-onset diabetes after kidney transplant be prevented? Diabetes Care 2013;36:1406-1412. Diabetes Care (2013) 0.89
The active metabolite of leflunomide, A77 1726, interferes with dendritic cell function. Arthritis Res Ther (2005) 0.88
HDL cholesterol efflux capacity and cardiovascular events. N Engl J Med (2015) 0.88
Vildagliptin and pioglitazone in patients with impaired glucose tolerance after kidney transplantation: a randomized, placebo-controlled clinical trial. Transplantation (2013) 0.87
Antithymocyte globulin impairs T-cell/antigen-presenting cell interaction: disruption of immunological synapse and conjugate formation. Transplantation (2007) 0.87
p38α senses environmental stress to control innate immune responses via mechanistic target of rapamycin. J Immunol (2013) 0.87
Effect of maintenance immunosuppressive drugs on virus pathobiology: evidence and potential mechanisms. Rev Med Virol (2012) 0.86
Maintenance immunosuppressive therapy and generic cyclosporine A use in adult renal transplantation: a single center analysis. Kidney Int Suppl (2010) 0.83
Blood volume-monitored regulation of ultrafiltration in fluid-overloaded hemodialysis patients: study protocol for a randomized controlled trial. Trials (2012) 0.83
Alemtuzumab (Campath-1H) induction therapy and dendritic cells: Impact on peripheral dendritic cell repertoire in renal allograft recipients. Transpl Immunol (2006) 0.82
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A randomized, placebo-controlled, double-blind, prospective trial to evaluate the effect of vildagliptin in new-onset diabetes mellitus after kidney transplantation. Trials (2010) 0.79
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Proteasome inhibition for recipient desensitization? A report of two sensitized kidney transplant candidates subjected to bortezomib treatment. Clin Transpl (2009) 0.76
The anti-inflammatory potency of dexamethasone is determined by the route of application in vivo. Immunol Lett (2010) 0.76
Detecting adaptive immunity: applications in transplantation monitoring. Mol Diagn Ther (2010) 0.76
Analysis of liver function in renal transplant recipients undergoing C2-monitoring for cyclosporine. Transpl Int (2007) 0.76
Inhibition of human dendritic cell maturation and function by the novel immunosuppressant FK778. Transplantation (2005) 0.76
Renin-Angiotensin System Fingerprints of Heart Failure With Reduced Ejection Fraction. J Am Coll Cardiol (2016) 0.75
Targeting the dysregulated mammalian target of rapamycin pathway in organ transplantation: killing 2 birds with 1 stone. Transplant Rev (Orlando) (2011) 0.75
Biological action of rapamycin in renal transplantation. Am J Kidney Dis (2008) 0.75
Addressing uncertainties in renal transplantation: hypomagnesemia and the case of diabetes prevention. Transpl Int (2014) 0.75
Molecular regulation of the renin-angiotensin system in haemodialysis patients. Nephrol Dial Transplant (2016) 0.75
Hereditary amyloidosis caused by R554L fibrinogen Aα-chain mutation in a Spanish family and review of the literature. Amyloid (2013) 0.75
Heart Failure with Preserved and Reduced Ejection Fraction in Hemodialysis Patients: Prevalence, Disease Prediction and Prognosis. Kidney Blood Press Res (2017) 0.75
Gross proteinuria and subacute renal failure after coronary angiography - a case report of cholesterol crystal embolization. Wien Klin Wochenschr (2010) 0.75