The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase.

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Published in Biochemistry on June 16, 2009

Authors

Peng Xie1, Craig Streu, Jie Qin, Howard Bregman, Nicholas Pagano, Eric Meggers, Ronen Marmorstein

Author Affiliations

1: The Wistar Institute, Philadelphia, Pennsylvania 19104-6323, USA.

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