Published in J Neurosci Res on August 15, 2009
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet (2008) 5.08
RNA polymerase II is required for RNAi-dependent heterochromatin assembly. Science (2005) 3.94
Eculizumab prevents anti-ganglioside antibody-mediated neuropathy in a murine model. Brain (2008) 2.60
Complex formation of Plk1 and INCENP required for metaphase-anaphase transition. Nat Cell Biol (2005) 2.41
Gangliosides GM1 and GM3 in the living cell membrane form clusters susceptible to cholesterol depletion and chilling. Mol Biol Cell (2007) 2.38
Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain-Barre syndrome. Proc Natl Acad Sci U S A (2004) 2.16
Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis. J Biol Chem (2004) 1.97
Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice. Brain (2010) 1.90
O-linked N-acetylglucosamine is present on the extracellular domain of notch receptors. J Biol Chem (2008) 1.65
The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis. Nat Med (2010) 1.63
Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer. Oncogene (2003) 1.47
Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins. J Biol Chem (2006) 1.44
O-linked-N-acetylglucosamine on extracellular protein domains mediates epithelial cell-matrix interactions. Nat Commun (2011) 1.42
b-series Ganglioside deficiency exhibits no definite changes in the neurogenesis and the sensitivity to Fas-mediated apoptosis but impairs regeneration of the lesioned hypoglossal nerve. J Biol Chem (2001) 1.38
Aurora-B associated protein phosphatases as negative regulators of kinase activation. Oncogene (2002) 1.37
Gangliosides contribute to stability of paranodal junctions and ion channel clusters in myelinated nerve fibers. Glia (2007) 1.36
Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec-7-dependent and -independent mechanisms. Eur J Immunol (2003) 1.35
Sialic acid-binding immunoglobulin-like lectin 7 mediates selective recognition of sialylated glycans expressed on Campylobacter jejuni lipooligosaccharides. Infect Immun (2006) 1.34
Gene therapy for mitochondrial disease by delivering restriction endonuclease SmaI into mitochondria. J Biomed Sci (2002) 1.29
Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C. J Biol Chem (2004) 1.23
Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1. J Cell Biol (2006) 1.23
O-linked-N-acetylglucosamine modification of mammalian Notch receptors by an atypical O-GlcNAc transferase Eogt1. Biochem Biophys Res Commun (2012) 1.21
Degradation of human Aurora-A protein kinase is mediated by hCdh1. FEBS Lett (2002) 1.20
Olfactory ensheathing cells induce less host astrocyte response and chondroitin sulphate proteoglycan expression than Schwann cells following transplantation into adult CNS white matter. Exp Neurol (2003) 1.16
Ganglioside antibodies and neuropathies. Curr Opin Neurol (2008) 1.15
Sialoadhesin promotes rapid proinflammatory and type I IFN responses to a sialylated pathogen, Campylobacter jejuni. J Immunol (2012) 1.14
Analysis of the role of Aurora B on the chromosomal targeting of condensin I. Nucleic Acids Res (2007) 1.14
Tolerance to self gangliosides is the major factor restricting the antibody response to lipopolysaccharide core oligosaccharides in Campylobacter jejuni strains associated with Guillain-Barré syndrome. Infect Immun (2002) 1.13
Immunologic glycosphingolipidomics and NKT cell development in mouse thymus. J Proteome Res (2009) 1.11
Anti-disialoside antibodies kill perisynaptic Schwann cells and damage motor nerve terminals via membrane attack complex in a murine model of neuropathy. Brain (2004) 1.10
Immunolocalization of GQ1b and related gangliosides in human extraocular neuromuscular junctions and muscle spindles. Invest Ophthalmol Vis Sci (2009) 1.09
Advances in understanding and treatment of immune-mediated disorders of the peripheral nervous system. Muscle Nerve (2004) 1.09
Analysis of lectin binding to glycolipid complexes using combinatorial glycoarrays. Glycobiology (2009) 1.06
Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis. Brain (2012) 1.06
Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells. Proc Natl Acad Sci U S A (2005) 1.06
Complex gangliosides at the neuromuscular junction are membrane receptors for autoantibodies and botulinum neurotoxin but redundant for normal synaptic function. J Neurosci (2002) 1.05
Cost-utility analysis of intravenous immunoglobulin and prednisolone for chronic inflammatory demyelinating polyradiculoneuropathy. Eur J Neurol (2003) 1.04
Mechanisms for the apoptosis of small cell lung cancer cells induced by anti-GD2 monoclonal antibodies: roles of anoikis. J Biol Chem (2005) 1.04
TRP channels and ASICs mediate mechanical hyperalgesia in models of inflammatory muscle pain and delayed onset muscle soreness. Pain (2008) 1.04
Astrocytes, but not olfactory ensheathing cells or Schwann cells, promote myelination of CNS axons in vitro. Glia (2008) 1.04
Overexpressed GM1 suppresses nerve growth factor (NGF) signals by modulating the intracellular localization of NGF receptors and membrane fluidity in PC12 cells. J Biol Chem (2004) 1.03
Long-term neurite orientation on astrocyte monolayers aligned by microtopography. Biomaterials (2007) 1.02
Overexpression of GD1a ganglioside sensitizes motor nerve terminals to anti-GD1a antibody-mediated injury in a model of acute motor axonal neuropathy. J Neurosci (2005) 1.02
Mitotic regulation of the stability of microtubule plus-end tracking protein EB3 by ubiquitin ligase SIAH-1 and Aurora mitotic kinases. J Biol Chem (2009) 1.02
Cholera toxin activates dendritic cells through dependence on GM1-ganglioside which is mediated by NF-kappaB translocation. Eur J Immunol (2003) 1.01
Pathophysiological actions of neuropathy-related anti-ganglioside antibodies at the neuromuscular junction. J Physiol (2009) 1.01
Functional duality of astrocytes in myelination. J Neurosci (2011) 1.01
Combinatorial glycoarray. Methods Mol Biol (2012) 1.01
The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice. J Clin Invest (2009) 1.00
Identification of nonepithelial multipotent cells in the embryonic olfactory mucosa. Stem Cells (2009) 1.00
Olfactory mucosa for transplant-mediated repair: a complex tissue for a complex injury? Glia (2010) 0.99
Overexpression of ganglioside GM1 results in the dispersion of platelet-derived growth factor receptor from glycolipid-enriched microdomains and in the suppression of cell growth signals. J Biol Chem (2002) 0.99
Gangliosides are essential in the protection of inflammation and neurodegeneration via maintenance of lipid rafts: elucidation by a series of ganglioside-deficient mutant mice. J Neurochem (2011) 0.98
Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire. J Neuroimmunol (2005) 0.98
Recent developments in Miller Fisher syndrome and related disorders. Curr Opin Neurol (2005) 0.98
Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues. Proc Natl Acad Sci U S A (2009) 0.97
Refractory skin injury in complex knock-out mice expressing only the GM3 ganglioside. J Biol Chem (2002) 0.97
Synthesis of disialyl Lewis a (Le(a)) structure in colon cancer cell lines by a sialyltransferase, ST6GalNAc VI, responsible for the synthesis of alpha-series gangliosides. J Biol Chem (2003) 0.96
Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains. J Biol Chem (2010) 0.96
GTDC2 modifies O-mannosylated α-dystroglycan in the endoplasmic reticulum to generate N-acetyl glucosamine epitopes reactive with CTD110.6 antibody. Biochem Biophys Res Commun (2013) 0.95
FGF/heparin differentially regulates Schwann cell and olfactory ensheathing cell interactions with astrocytes: a role in astrocytosis. J Neurosci (2007) 0.95
Innate murine B cells produce anti-disialosyl antibodies reactive with Campylobacter jejuni LPS and gangliosides that are polyreactive and encoded by a restricted set of unmutated V genes. J Neuroimmunol (2004) 0.94
Immunoglobulins inhibit pathophysiological effects of anti-GQ1b-positive sera at motor nerve terminals through inhibition of antibody binding. Brain (2003) 0.94
Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells. Biochim Biophys Acta (2007) 0.94
Murine glycosyltransferases responsible for the expression of globo-series glycolipids: cDNA structures, mRNA expression, and distribution of their products. Glycobiology (2005) 0.93
Reduced motor and sensory functions and emotional response in GM3-only mice: emergence from early stage of life and exacerbation with aging. Behav Brain Res (2008) 0.93
Acute immunoinflammatory neuropathy: update on Guillain-Barré syndrome. Curr Opin Neurol (2002) 0.92
An open label clinical trial of complement inhibition in multifocal motor neuropathy. J Peripher Nerv Syst (2011) 0.92
Calpain inhibitors protect against axonal degeneration in a model of anti-ganglioside antibody-mediated motor nerve terminal injury. Brain (2003) 0.92
Complement inhibition abrogates nerve terminal injury in Miller Fisher syndrome. Ann Neurol (2005) 0.92
Clostridium perfringens alpha-toxin recognizes the GM1a-TrkA complex. J Biol Chem (2012) 0.92
C9-R95X polymorphism in patients with neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci (2012) 0.92
N-cadherin differentially determines Schwann cell and olfactory ensheathing cell adhesion and migration responses upon contact with astrocytes. Mol Cell Neurosci (2005) 0.91
Time-lapse imaging of the dynamics of CNS glial-axonal interactions in vitro and ex vivo. PLoS One (2012) 0.91
Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties. Cancer Sci (2007) 0.91
Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosis. J Neuroimmunol (2011) 0.91
Gangliosides determine the amyloid pathology of Alzheimer's disease. Neuroreport (2009) 0.91
Role of Mayven, a kelch-related protein in oligodendrocyte process formation. J Neurosci Res (2005) 0.90
Adenovirus type 21-associated acute flaccid paralysis during an outbreak of hand-foot-and-mouth disease in Sarawak, Malaysia. Clin Infect Dis (2003) 0.90
Astrocyte phenotypes and their relationship to myelination. J Anat (2010) 0.90
Different response of the knockout mice lacking b-series gangliosides against botulinum and tetanus toxins. Biochim Biophys Acta (2005) 0.90
Subclass IgG to motor gangliosides related to infection and clinical course in Guillain-Barré syndrome. J Neuroimmunol (2008) 0.89
Meningeal cells enhance limited CNS remyelination by transplanted olfactory ensheathing cells. Brain (2003) 0.89
Identification of a Drosophila gene encoding xylosylprotein beta4-galactosyltransferase that is essential for the synthesis of glycosaminoglycans and for morphogenesis. J Biol Chem (2002) 0.89
Essential roles of gangliosides in the formation and maintenance of membrane microdomains in brain tissues. Neurochem Res (2012) 0.89
The blood group P1 synthase gene is identical to the Gb3/CD77 synthase gene. A clue to the solution of the P1/P2/p puzzle. J Biol Chem (2003) 0.89
Identity, developmental restriction and reactivity of extralaminar cells capping mammalian neuromuscular junctions. J Cell Sci (2008) 0.89
Complex gangliosides as autoantibody targets at the neuromuscular junction in Miller Fisher syndrome: a current perspective. Neurochem Res (2002) 0.88
Proteomic analysis of ganglioside-associated membrane molecules: substantial basis for molecular clustering. Proteomics (2012) 0.88
A novel, promoter-based, target-specific assay identifies 2-deoxy-D-glucose as an inhibitor of globotriaosylceramide biosynthesis. FEBS J (2009) 0.88
β4GalT6 is involved in the synthesis of lactosylceramide with less intensity than β4GalT5. Glycobiology (2013) 0.87