Intracranial V. cholerae sialidase protects against excitotoxic neurodegeneration.

PubWeight™: 0.83‹?›

🔗 View Article (PMC 3240658)

Published in PLoS One on December 15, 2011

Authors

Anandh Dhanushkodi1, Michael P McDonald

Author Affiliations

1: Department of Neurology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America.

Articles cited by this

Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr Clin Neurophysiol (1972) 16.34

Chemical diversity in the sialic acids and related alpha-keto acids: an evolutionary perspective. Chem Rev (2002) 4.61

Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze. Behav Neurosci (1993) 4.33

Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. Neuroscience (1985) 3.53

Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1. Cell (1997) 3.10

Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism. Nat Genet (1995) 2.64

Numerous candidate plasticity-related genes revealed by differential cDNA cloning. Nature (1993) 2.63

Enhanced insulin sensitivity in mice lacking ganglioside GM3. Proc Natl Acad Sci U S A (2003) 2.56

Hyperactivity and intact hippocampus-dependent learning in mice lacking the M1 muscarinic acetylcholine receptor. J Neurosci (2001) 2.54

Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities. Neurobiol Dis (2005) 2.22

Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system. Proc Natl Acad Sci U S A (1996) 2.10

Recurrent spontaneous motor seizures after repeated low-dose systemic treatment with kainate: assessment of a rat model of temporal lobe epilepsy. Epilepsy Res (1998) 1.96

Impaired spatial learning in the APPSwe + PSEN1DeltaE9 bigenic mouse model of Alzheimer's disease. Genes Brain Behav (2007) 1.72

Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease--a review. J Lipid Res (2008) 1.68

Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures. J Biol Chem (2000) 1.64

Mice lacking both subunits of lysosomal beta-hexosaminidase display gangliosidosis and mucopolysaccharidosis. Nat Genet (1996) 1.63

Requirement for GD3 ganglioside in CD95- and ceramide-induced apoptosis. Science (1997) 1.53

Endogenous anxiety and stress responses in water maze and Barnes maze spatial memory tasks. Behav Brain Res (2008) 1.51

Bone marrow transplantation prolongs life span and ameliorates neurologic manifestations in Sandhoff disease mice. J Clin Invest (1998) 1.49

Sialic acid recognition by Vibrio cholerae neuraminidase. J Biol Chem (2004) 1.39

Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid. J Neurochem (2008) 1.35

Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex. Proc Natl Acad Sci U S A (1988) 1.21

Elimination of GD3 synthase improves memory and reduces amyloid-beta plaque load in transgenic mice. Neurobiol Aging (2008) 1.19

Apoptogenic ganglioside GD3 directly induces the mitochondrial permeability transition. J Biol Chem (1999) 1.11

Deficits in acetylcholine homeostasis, receptors and behaviors in choline transporter heterozygous mice. Genes Brain Behav (2006) 1.09

Impaired spatial memory in APP-overexpressing mice on a homocysteinemia-inducing diet. Neurobiol Aging (2006) 1.08

Sialidase enhances spinal axon outgrowth in vivo. Proc Natl Acad Sci U S A (2006) 1.08

Differential distribution of major gangliosides in rat central nervous system detected by specific monoclonal antibodies. Glycobiology (1993) 1.05

Commitment to apoptosis by GD3 ganglioside depends on opening of the mitochondrial permeability transition pore. J Biol Chem (1999) 1.05

Enhanced susceptibility to kainate-induced seizures, neuronal apoptosis, and death in mice lacking gangliotetraose gangliosides: protection with LIGA 20, a membrane-permeant analog of GM1. J Neurosci (2005) 1.04

Hyperactivity and learning deficits in transgenic mice bearing a human mutant thyroid hormone beta1 receptor gene. Learn Mem (1999) 1.04

GM1 ganglioside in Parkinson's disease: Results of a five year open study. J Neurol Sci (2010) 1.02

Vitamin C reduces spatial learning deficits in middle-aged and very old APP/PSEN1 transgenic and wild-type mice. Pharmacol Biochem Behav (2009) 1.02

Cell death and synaptic reorganizations produced by seizures. Epilepsia (2001) 1.00

Glycosphingolipids and mitochondria: role in apoptosis and disease. Glycoconj J (2004) 0.98

Antioxidants and cognitive training interact to affect oxidative stress and memory in APP/PSEN1 mice. Nutr Neurosci (2009) 0.98

Effects of gangliosides on ethanol-induced neurodegeneration in the developing mouse brain. Alcohol Clin Exp Res (2007) 0.96

Mouse model of GM2 activator deficiency manifests cerebellar pathology and motor impairment. Proc Natl Acad Sci U S A (1997) 0.96

Transgenic mice expressing a human mutant beta1 thyroid receptor are hyperactive, impulsive, and inattentive. Genes Brain Behav (2006) 0.95

Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells. J Exp Med (1998) 0.94

Prevention of apoptotic neuronal death by GM1 ganglioside. Involvement of Trk neurotrophin receptors. J Biol Chem (1995) 0.93

Alteration of ganglioside synthesis by GM3 synthase knockout in murine embryonic fibroblasts. Biochim Biophys Acta (2007) 0.92

Cholera toxin B subunit binding does not correlate with GM1 expression: a study using mouse embryonic neural precursor cells. Glycobiology (2006) 0.92

Ganglioside metabolism in a transgenic mouse model of Alzheimer's disease: expression of Chol-1α antigens in the brain. ASN Neuro (2010) 0.91

Potentiation of a sodium-calcium exchanger in the nuclear envelope by nuclear GM1 ganglioside. J Neurochem (2002) 0.91

Hyperactivity, impaired learning on a vigilance task, and a differential response to methylphenidate in the TRbetaPV knock-in mouse. Psychopharmacology (Berl) (2005) 0.91

Is exposure to enriched environment beneficial for functional post-lesional recovery in temporal lobe epilepsy? Neurosci Biobehav Rev (2007) 0.89

Beta-amyloid-induced synthesis of the ganglioside GD3 is a requisite for cell cycle reactivation and apoptosis in neurons. J Neurosci (2002) 0.89

The ganglioside GD3 as the Greek goddess Hecate: several faces turned towards as many directions. IUBMB Life (2005) 0.89

Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice. Pharmacol Biochem Behav (2009) 0.88

Gangliosides activate Trk receptors by inducing the release of neurotrophins. J Biol Chem (2002) 0.88

Immunostaining of ganglioside GD1b, GD3 and GM1 in rat cerebellum: cellular layer and cell type specific associations. J Neurosci Res (2000) 0.86

Parkinson's disease: improved function with GM1 ganglioside treatment in a randomized placebo-controlled study. Neurology (1998) 0.86

Ganglioside GM1 attenuates scopolamine-induced amnesia in rats and mice. Psychopharmacology (Berl) (1999) 0.85

Motor deficits in fibroblast growth factor receptor-3 null mutant mice. Behav Pharmacol (2001) 0.85

Modulation of a Ca2+ signaling pathway by GM1 ganglioside in PC12 cells. J Biol Chem (1992) 0.85

GM1 ganglioside treatment of Parkinson's disease: an open pilot study of safety and efficacy. Neurology (1995) 0.83

Brain-derived neurotrophic factor selectively rescues mesencephalic dopaminergic neurons from 2,4,5-trihydroxyphenylalanine-induced injury. J Neurosci Res (1993) 0.83

An early increase in the disialoganglioside GD3 contributes to the development of neuronal apoptosis in culture. Cell Death Differ (2002) 0.83

Influence of endogenous GM1 ganglioside on TrkB activity, in cultured neurons. FEBS Lett (1998) 0.82

Ganglioside patterns in amyotrophic lateral sclerosis brain regions. Ann Neurol (1985) 0.81

An efficient approach to N-acetyl-D-glucosaminuronic acid-based sialylmimetics as potential sialidase inhibitors. Bioorg Med Chem Lett (2004) 0.80

Preservation of mitochondrial integrity and energy metabolism during experimental status epilepticus leads to neuronal apoptotic cell death in the hippocampus of the rat. Seizure (2009) 0.80

Gangliosides prevent excitotoxicity through activation of TrkB receptor. Neurotox Res (2002) 0.80

Evidence that ruthenium red disturbs the synaptic transmission in the rat hippocampal slices through interacting with sialic acid residues. Brain Res (1986) 0.80

GM1 ganglioside protects nucleus basalis from excitotoxin damage: reduced cortical cholinergic losses and animal mortality. J Neurosci Res (1988) 0.79

Prevention of neuronal apoptotic death by neurotrophic agents and ganglioside GM1: insights and speculations regarding a common mechanism. Perspect Dev Neurobiol (1996) 0.79

Monosialoganglioside GM1 in cerebral ischemia. Cerebrovasc Brain Metab Rev (1991) 0.79

Lipid signaling in CD95-mediated apoptosis. FEBS Lett (1999) 0.78

GM1 and NGF modulate Ca2+ homeostasis and GAP43 mRNA expression in cultured dorsal root ganglion neurons with excitotoxicity induced by glutamate. Nutr Neurosci (2007) 0.77

Systemic treatment with GM1 ganglioside improves survival and function of cryopreserved embryonic midbrain grafted to the 6-hydroxydopamine-lesioned rat striatum. Exp Neurol (2000) 0.77

In vitro analysis of glial cell function in ganglioside-deficient mice. J Neurosci Res (2009) 0.77

The effect of X-radiation on cerebellar granule cells grown in culture. Ganglioside GM1 neuroprotective activity. Neurochem Int (1996) 0.76

Temporal changes in edema, Na+, K+, and Ca++ in focal cortical stroke: GM1 ganglioside reduces ischemic injury. J Neurosci Res (1991) 0.76

Monosialoganglioside (GM1) restores membrane fatty acid levels in ischemic tissue after cortical focal ischemia in rat. Neurochem Int (1993) 0.76

Local addition of monosialoganglioside GM1 stimulates peripheral axon regeneration in vivo. Braz J Med Biol Res (1993) 0.75

Articles by these authors

Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease--a review. J Lipid Res (2008) 1.68

The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum. Nat Genet (2002) 1.51

Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid. J Neurochem (2008) 1.35

Spatial and nonspatial escape strategies in the Barnes maze. Learn Mem (2006) 1.33

Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model. J Neurosci (2008) 1.30

Elimination of GD3 synthase improves memory and reduces amyloid-beta plaque load in transgenic mice. Neurobiol Aging (2008) 1.19

Impaired spatial memory in APP-overexpressing mice on a homocysteinemia-inducing diet. Neurobiol Aging (2006) 1.08

Hyperactivity, impaired learning on a vigilance task, and a differential response to methylphenidate in the TRbetaPV knock-in mouse. Psychopharmacology (Berl) (2005) 0.91

Ganglioside metabolism in a transgenic mouse model of Alzheimer's disease: expression of Chol-1α antigens in the brain. ASN Neuro (2010) 0.91

Dicinnamoylquinides in roasted coffee inhibit the human adenosine transporter. Eur J Pharmacol (2002) 0.86

Fluorescence spectroscopy of an in vitro model of human cervical precancer identifies neoplastic phenotype. Int J Cancer (2007) 0.78

Brain gangliosides of a transgenic mouse model of Alzheimer's disease with deficiency in GD3-synthase: expression of elevated levels of a cholinergic-specific ganglioside, GT1aα. ASN Neuro (2013) 0.77

4-Caffeoyl-1,5-quinide in roasted coffee inhibits [3H]naloxone binding and reverses anti-nociceptive effects of morphine in mice. Psychopharmacology (Berl) (2004) 0.76