Published in Neuroscience on April 21, 2009
Antioxidant therapies for traumatic brain injury. Neurotherapeutics (2010) 1.73
Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury. J Neuroinflammation (2014) 1.04
Stem cell therapy and curcumin synergistically enhance recovery from spinal cord injury. PLoS One (2014) 1.02
A pyrazole curcumin derivative restores membrane homeostasis disrupted after brain trauma. Exp Neurol (2010) 1.01
Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease. Mol Neurodegener (2012) 0.93
Perspectives on molecular biomarkers of oxidative stress and antioxidant strategies in traumatic brain injury. Biomed Res Int (2014) 0.91
Diet and cognition: interplay between cell metabolism and neuronal plasticity. Curr Opin Clin Nutr Metab Care (2013) 0.88
Molecular and physiological responses to juvenile traumatic brain injury: focus on growth and metabolism. Dev Neurosci (2010) 0.88
Molecular chaperone dysfunction in neurodegenerative diseases and effects of curcumin. Biomed Res Int (2014) 0.87
Collaborative effects of diet and exercise on cognitive enhancement. Nutr Health (2011) 0.86
Natural plant products and extracts that reduce immunoexcitotoxicity-associated neurodegeneration and promote repair within the central nervous system. Surg Neurol Int (2012) 0.86
Effects of diet and/or exercise in enhancing spinal cord sensorimotor learning. PLoS One (2012) 0.85
Neuroprotective effect of Pycnogenol® following traumatic brain injury. Exp Neurol (2012) 0.84
The combined effects of exercise and foods in preventing neurological and cognitive disorders. Prev Med (2011) 0.83
Dietary therapy to promote neuroprotection in chronic spinal cord injury. J Neurosurg Spine (2012) 0.80
Dose- and time-dependent neuroprotective effects of Pycnogenol following traumatic brain injury. J Neurotrauma (2013) 0.80
Curcumin boosts DHA in the brain: Implications for the prevention of anxiety disorders. Biochim Biophys Acta (2014) 0.79
Stuck at the bench: Potential natural neuroprotective compounds for concussion. Surg Neurol Int (2011) 0.78
Supplemental substances derived from foods as adjunctive therapeutic agents for treatment of neurodegenerative diseases and disorders. Adv Nutr (2014) 0.76
Using the olfactory system as an in vivo model to study traumatic brain injury and repair. J Neurotrauma (2014) 0.76
Traumatic brain injury decreases AMP-activated protein kinase activity and pharmacological enhancement of its activity improves cognitive outcome. J Neurochem (2016) 0.75
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science (2000) 12.98
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell (2005) 11.19
Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc Natl Acad Sci U S A (2004) 9.25
The AMP-activated protein kinase pathway--new players upstream and downstream. J Cell Sci (2004) 5.65
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat Genet (2000) 5.42
Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J Biol Chem (2004) 5.14
Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. Eur J Neurosci (2004) 4.64
Calorie restriction extends yeast life span by lowering the level of NADH. Genes Dev (2004) 4.51
The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci (2001) 3.92
A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation. FASEB J (1997) 2.56
AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation. J Mol Neurosci (2001) 2.51
Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma. Nat Med (2003) 2.35
Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology. Neurobiol Aging (2001) 2.20
Apolipoprotein E polymorphism and Alzheimer disease: The Indo-US Cross-National Dementia Study. Arch Neurol (2000) 2.04
The causes and functions of mitochondrial proton leak. Biochim Biophys Acta (1994) 2.02
Nitric oxide and mitochondrial biogenesis. J Cell Sci (2006) 1.89
Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells. Biochem J (2002) 1.87
Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease. J Pharmacol Exp Ther (2008) 1.86
Creatine kinase of rat heart mitochondria. Coupling of creatine phosphorylation to electron transport. J Biol Chem (1973) 1.79
Brain-derived neurotrophic factor functions as a metabotrophin to mediate the effects of exercise on cognition. Eur J Neurosci (2008) 1.74
Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease. J Neurosci (2005) 1.67
Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition. Exp Neurol (2005) 1.60
Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats. Life Sci (2004) 1.57
A saturated-fat diet aggravates the outcome of traumatic brain injury on hippocampal plasticity and cognitive function by reducing brain-derived neurotrophic factor. Neuroscience (2003) 1.56
Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus. J Biol Chem (2008) 1.55
Mitochondrial uncoupling protein-2 protects the immature brain from excitotoxic neuronal death. Ann Neurol (2003) 1.54
Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury. Free Radic Biol Med (2008) 1.48
Brain uncoupling protein 2: uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers. J Neurosci (1999) 1.48
Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury. J Neurotrauma (1997) 1.37
On the mechanism of fatty acid-induced proton transport by mitochondrial uncoupling protein. J Biol Chem (1996) 1.35
Mitochondrial damage and dysfunction in traumatic brain injury. Mitochondrion (2004) 1.30
Omega-3 fatty acids supplementation restores mechanisms that maintain brain homeostasis in traumatic brain injury. J Neurotrauma (2007) 1.28
Coupling energy metabolism with a mechanism to support brain-derived neurotrophic factor-mediated synaptic plasticity. Neuroscience (2006) 1.23
Brain mitochondrial uncoupling protein 2 (UCP2): a protective stress signal in neuronal injury. Biochem Pharmacol (2002) 1.21
Diffuse prolonged depression of cerebral oxidative metabolism following concussive brain injury in the rat: a cytochrome oxidase histochemistry study. Brain Res (1991) 1.21
Neuroprotective effect of curcumin on transient focal cerebral ischemia in rats. Brain Res (2008) 1.20
Kinase-independent transcriptional co-activation of peroxisome proliferator-activated receptor alpha by AMP-activated protein kinase. Biochem J (2004) 1.18
Nutritional status, cognition, and survival: a new role for leptin and AMP kinase. J Biol Chem (2005) 1.14
Regional changes in interstitial K+ and Ca2+ levels following cortical compression contusion trauma in rats. J Cereb Blood Flow Metab (1993) 1.14
Age-dependency of 45calcium accumulation following lateral fluid percussion: acute and delayed patterns. J Neurotrauma (2001) 1.12
Mitochondrial creatine kinase mediates contact formation between mitochondrial membranes. J Biol Chem (1991) 1.12
Mitochondrial uncoupling proteins in the central nervous system. Antioxid Redox Signal (2005) 1.11
Purinergic transmission in the central nervous system. Pflugers Arch (2006) 1.09
Sequential changes in the signal transduction responses of skeletal muscle following food deprivation. FASEB J (2006) 1.03
Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats. J Neurotrauma (2001) 0.99
Physiological glucose is critical for optimized neuronal viability and AMPK responsiveness in vitro. J Neurosci Methods (2007) 0.98
Restricted neuronal expression of ubiquitous mitochondrial creatine kinase: changing patterns in development and with increased activity. Mol Cell Biochem (2003) 0.97
Uncoupling of local cerebral glucose metabolism and blood flow after acute fluid-percussion injury in rats. Am J Physiol (1997) 0.96
Prevention of kainic acid-induced changes in nitric oxide level and neuronal cell damage in the rat hippocampus by manganese complexes of curcumin and diacetylcurcumin. Life Sci (2005) 0.95
Suppression of the inducible form of nitric oxide synthase prior to traumatic brain injury improves cytochrome c oxidase activity and normalizes cellular energy levels. Neuroscience (2007) 0.93
Evolution of creatine kinase. Nature (1967) 0.89
Acute disruption of cytochrome oxidase activity in brain in a perinatal rat stroke model. Pediatr Res (1994) 0.88
Cerebral synaptic transmission during anoxia is protected by creatine. J Neurochem (1981) 0.88
Decrease of intracellular ATP content downregulated UCP2 expression in mouse hepatocytes. Biochem Biophys Res Commun (2003) 0.88
Free radical scavenger posttreatment improves functional and morphological outcome after fluid percussion injury in the rat. J Neurotrauma (2001) 0.87
Compartmentation of brain-type creatine kinase and ubiquitous mitochondrial creatine kinase in neurons: evidence for a creatine phosphate energy shuttle in adult rat brain. J Comp Neurol (1994) 0.86
Transcriptional regulation of neuronal genes and its effect on neural functions: NAD-dependent histone deacetylase SIRT1 (Sir2alpha). J Pharmacol Sci (2005) 0.85
Traumatic brain injury-induced changes in gene expression and functional activity of mitochondrial cytochrome C oxidase. J Neurotrauma (2001) 0.84
Cannabinoids as neuroprotective agents in traumatic brain injury. Curr Pharm Des (2004) 0.84
Brain distribution of UCP2 mRNA: in situ hybridization histochemistry studies. Int J Obes Relat Metab Disord (1999) 0.83
Quantitative detection of the expression of mitochondrial cytochrome c oxidase subunits mRNA in the cerebral cortex after experimental traumatic brain injury. Brain Res (2008) 0.82
Induction of Ucp2 expression in brain phagocytes and neurons following murine toxoplasmosis: an essential role of IFN-gamma and an association with negative energy balance. J Neuroimmunol (2007) 0.80
Expression of brain-type creatine kinase and ubiquitous mitochondrial creatine kinase in the fetal rat brain: evidence for a nuclear energy shuttle. J Comp Neurol (1995) 0.78
Complementary DNA sequencing: expressed sequence tags and human genome project. Science (1991) 19.42
A compensatory base change in U1 snRNA suppresses a 5' splice site mutation. Cell (1986) 9.65
Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts. Nature (1999) 6.50
American College of Rheumatology classification criteria for Sjögren's syndrome: a data-driven, expert consensus approach in the Sjögren's International Collaborative Clinical Alliance cohort. Arthritis Care Res (Hoboken) (2012) 4.82
Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus. Genes Dev (1995) 4.11
Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction. Mol Cell Biol (1999) 3.55
Effect of fixation on the amplification of nucleic acids from paraffin-embedded material by the polymerase chain reaction. J Histochem Cytochem (1991) 3.51
Model-checking techniques based on cumulative residuals. Biometrics (2002) 2.58
A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning. Neuroscience (2002) 2.58
Permanent prostate seed implant brachytherapy: report of the American Association of Physicists in Medicine Task Group No. 64. Med Phys (1999) 2.47
Quitting cigarettes completely or switching to smokeless tobacco: do US data replicate the Swedish results? Tob Control (2009) 2.36
High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice. Mol Cell Biol (1997) 2.19
Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase. Science (1999) 2.17
Voluntary exercise following traumatic brain injury: brain-derived neurotrophic factor upregulation and recovery of function. Neuroscience (2004) 2.15
Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite. J Neurochem (1997) 2.13
Macrocytosis of chronic alcoholism. Lancet (1974) 2.05
Smoking, air pollution, and the high rates of lung cancer in Shenyang, China. J Natl Cancer Inst (1989) 1.99
Differential regulation by exercise of BDNF and NT-3 in rat spinal cord and skeletal muscle. Eur J Neurosci (2001) 1.95
Mekk3 is essential for early embryonic cardiovascular development. Nat Genet (2000) 1.95
Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic-plasticity. Neuroscience (2003) 1.83
Insulin-like growth factor I interfaces with brain-derived neurotrophic factor-mediated synaptic plasticity to modulate aspects of exercise-induced cognitive function. Neuroscience (2006) 1.72
Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB. Mol Cell Biol (2000) 1.70
Exercise reverses the harmful effects of consumption of a high-fat diet on synaptic and behavioral plasticity associated to the action of brain-derived neurotrophic factor. Neuroscience (2004) 1.69
Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene. Mol Cell Biol (1999) 1.66
Rickettsial relative associated with papaya bunchy top disease. Curr Microbiol (1998) 1.61
Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance? Behav Neurosci (1998) 1.57
A saturated-fat diet aggravates the outcome of traumatic brain injury on hippocampal plasticity and cognitive function by reducing brain-derived neurotrophic factor. Neuroscience (2003) 1.56
Folate deficiency in the alcoholic--its relationship to clinical and haematological abnormalities, liver disease and folate stores. Br J Haematol (1975) 1.52
Risk factors for local and regional recurrence in patients with resected N0-N1 non-small-cell lung cancer, with implications for patient selection for adjuvant radiation therapy. Ann Oncol (2012) 1.50
Exercise impacts brain-derived neurotrophic factor plasticity by engaging mechanisms of epigenetic regulation. Eur J Neurosci (2010) 1.48
Schwann cells and astrocytes induce synapse formation by spinal motor neurons in culture. Mol Cell Neurosci (2004) 1.47
Non-invasive brain stimulation for Parkinson's disease: a systematic review and meta-analysis of the literature. J Neurol Neurosurg Psychiatry (2005) 1.46
BDNF-exercise interactions in the recovery of symmetrical stepping after a cervical hemisection in rats. Neuroscience (2008) 1.43
A clinical and laboratory study to compare the addition of 0.2 mg of morphine, 0.2 mg of epinephrine, or their combination to hyperbaric bupivacaine for spinal anesthesia in cesarean section. Anesth Analg (1993) 1.43
Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus. Hum Gene Ther (1999) 1.43
Agonist induced homologous desensitization of mu-opioid receptors mediated by G protein-coupled receptor kinases is dependent on agonist efficacy. Mol Pharmacol (1998) 1.43
A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis. J Immunol (1999) 1.41
Docosahexaenoic acid dietary supplementation enhances the effects of exercise on synaptic plasticity and cognition. Neuroscience (2008) 1.41
Pulmonary pathological features in coronavirus associated severe acute respiratory syndrome (SARS). J Clin Pathol (2004) 1.39
A multicenter study of primary graft failure after infant heart transplantation: impact of extracorporeal membrane oxygenation on outcomes. Pediatr Transplant (2013) 1.38
Multiple paths of sugar-sensing and a sugar/oxygen overlap for genes of sucrose and ethanol metabolism. J Exp Bot (2000) 1.37
Conventional 3D conformal versus intensity-modulated radiotherapy for the adjuvant treatment of gynecologic malignancies: a comparative dosimetric study of dose-volume histograms. Gynecol Oncol (2003) 1.26
BDNF and learning: Evidence that instrumental training promotes learning within the spinal cord by up-regulating BDNF expression. Neuroscience (2007) 1.25
The valuation of states of ill-health: the impact of age and disability. Age Ageing (1991) 1.24
Elevated serum gamma-glutamyl-transferase (transpeptidase) and histological liver damage in alcoholism. Am J Gastroenterol (1976) 1.23
Coupling energy metabolism with a mechanism to support brain-derived neurotrophic factor-mediated synaptic plasticity. Neuroscience (2006) 1.23
Bacterial meningitis in Hong Kong: 10-years' experience. Clin Neurol Neurosurg (2004) 1.21
Powerful dominant negative mutants of the human estrogen receptor. J Biol Chem (1993) 1.21
Temporal lobe epilepsy due to hippocampal sclerosis in pediatric candidates for epilepsy surgery. Neurology (2001) 1.21
Improved survival outcomes with the incidental use of beta-blockers among patients with non-small-cell lung cancer treated with definitive radiation therapy. Ann Oncol (2013) 1.20
Three phases in homologous pairing: polymerization of recA protein on single-stranded DNA, synapsis, and polar strand exchange. Cold Spring Harb Symp Quant Biol (1983) 1.20
Characterization of potent Na+/H+ exchange inhibitors from the amiloride series in A431 cells. Biochemistry (1984) 1.19
Opposing effects of reactive oxygen species and cholesterol on endothelial nitric oxide synthase and endothelial cell caveolae. Circ Res (1999) 1.18
Improved early results of elective hepatic resection for liver tumors. One hundred consecutive hepatectomies in cirrhotic and noncirrhotic patients. Arch Surg (1989) 1.18
Formyl peptide chemoattractants: a model of the receptor on rabbit neutrophils. Biochemistry (1982) 1.17
Genetic tuning of the novel avian influenza A(H7N9) virus during interspecies transmission, China, 2013. Euro Surveill (2014) 1.16
The select action of hippocampal calcium calmodulin protein kinase II in mediating exercise-enhanced cognitive function. Neuroscience (2006) 1.16
Status epilepticus-induced neuronal loss in humans without systemic complications or epilepsy. Epilepsia (2000) 1.15
DRB1*04 and DQ alleles: expression of 21-hydroxylase autoantibodies and risk of progression to Addison's disease. J Clin Endocrinol Metab (1999) 1.14
Occupational exposure to environmental tobacco smoke. JAMA (1996) 1.13
Prognosis-based futility guidelines: does anyone win? SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatment. J Am Geriatr Soc (1994) 1.13
Voluntary exercise or amphetamine treatment, but not the combination, increases hippocampal brain-derived neurotrophic factor and synapsin I following cortical contusion injury in rats. Neuroscience (2008) 1.13
Increased expression of keratinocyte growth factor messenger RNA associated with inflammatory bowel disease. Gastroenterology (1996) 1.11
Immunoglobulin and T-cell receptor beta-chain gene rearrangement analysis of Hodgkin's disease: implications for lineage determination and differential diagnosis. Proc Natl Acad Sci U S A (1986) 1.10
Efficient generation of multi-copy strains for optimizing secretory expression of porcine insulin precursor in yeast Pichia pastoris. J Appl Microbiol (2009) 1.07
The 2S albumin allergens of Arachis hypogaea, Ara h 2 and Ara h 6, are the major elicitors of anaphylaxis and can effectively desensitize peanut-allergic mice. Clin Exp Allergy (2012) 1.06
[Severe acute respiratory syndrome (SARS)]. Pneumologie (2003) 1.06
Stepwise deletions of polyA sequences in mismatch repair-deficient colorectal cancers. Am J Pathol (2001) 1.04
Analysis of mechanisms that determine dominant negative estrogen receptor effectiveness. J Biol Chem (1995) 1.03
Exercise influences hippocampal plasticity by modulating brain-derived neurotrophic factor processing. Neuroscience (2011) 1.01
Ethnic distribution of amyloidosis: an autopsy study. Mod Pathol (1989) 1.01
Radiosurgery and brain tolerance: an analysis of neurodiagnostic imaging changes after gamma knife radiosurgery for arteriovenous malformations. Int J Radiat Oncol Biol Phys (1992) 1.01
Transformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling. Oncogene (2006) 1.01
Concept of dose nonuniformity in interstitial brachytherapy. Int J Radiat Oncol Biol Phys (1993) 1.00
Phospholipid spin probes measure the effects of ethanol on the molecular order of liver microsomes. Biochemistry (1985) 0.98
Potential therapeutic effects of exercise to the brain. Curr Med Chem (2007) 0.98
Group sequential designs for monitoring survival probabilities. Biometrics (1996) 0.98
Global impact and application of the anaerobic ammonium-oxidizing (anammox) bacteria. Biochem Soc Trans (2006) 0.97
Environmental determinants of lung cancer in Shenyang, China. IARC Sci Publ (1991) 0.96
Helicobacter pylori sero-prevalence in asthma. Respir Med (2000) 0.95
Severe acute respiratory syndrome: report of treatment and outcome after a major outbreak. Thorax (2004) 0.95
CPEB1, a histone-modified hypomethylated gene, is regulated by miR-101 and involved in cell senescence in glioma. Cell Death Dis (2013) 0.94
Mechanisms of epileptogenicity in cortical dysplasias. Neurology (2004) 0.94
Capsid assembly and involved function analysis of twelve core protein mutants of duck hepatitis B virus. J Virol (1994) 0.94
Bacterial polysaccharides as vaccines--immunity and chemical characterization. Adv Exp Med Biol (2001) 0.93
Probing the molecular architecture of (1,3)-beta-glucan (callose) synthase: polypeptide depletion studies. Biochem Soc Trans (1992) 0.93
Anti-oxidant vitamins reduce normal tissue toxicity induced by radio-immunotherapy. Int J Cancer (2000) 0.92