Published in FASEB J on August 01, 1997
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Glutathionylation acts as a control switch for uncoupling proteins UCP2 and UCP3. J Biol Chem (2011) 1.53
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Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages. Proc Natl Acad Sci U S A (2002) 1.26
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Enhancing repair of the mammalian heart. Circ Res (2007) 1.21
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Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation. Cancer Chemother Pharmacol (2010) 1.10
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Genipin-induced inhibition of uncoupling protein-2 sensitizes drug-resistant cancer cells to cytotoxic agents. PLoS One (2010) 1.09
Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury. Hepatology (2008) 1.07
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Cardiolipins and mitochondrial proton-selective leakage. J Bioenerg Biomembr (1998) 1.05
Negative regulation of UCP2 by TGFβ signaling characterizes low and intermediate-grade primary breast cancer. Cell Death Dis (2010) 1.05
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Mitochondrial uncoupling inhibits p53 mitochondrial translocation in TPA-challenged skin epidermal JB6 cells. PLoS One (2010) 0.98
Expression of UCP3 in CHO cells does not cause uncoupling, but controls mitochondrial activity in the presence of glucose. Biochem J (2006) 0.98
Interaction between the UCP2-866G/A, mtDNA 10398G/A and PGC1alpha p.Thr394Thr and p.Gly482Ser polymorphisms in type 2 diabetes susceptibility in North Indian population. Hum Genet (2007) 0.98
Mitochondrial Ca2+, the secret behind the function of uncoupling proteins 2 and 3? Cell Calcium (2008) 0.97
Mitochondria and redox signaling in steatohepatitis. Antioxid Redox Signal (2011) 0.96
Two tales of antioxidant enzymes on β cells and diabetes. Antioxid Redox Signal (2010) 0.95
The role of mitochondrial uncoupling proteins in lifespan. Pflugers Arch (2009) 0.93
Further support to the uncoupling-to-survive theory: the genetic variation of human UCP genes is associated with longevity. PLoS One (2011) 0.93
Impaired expression of uncoupling protein 2 causes defective postischemic angiogenesis in mice deficient in AMP-activated protein kinase α subunits. Arterioscler Thromb Vasc Biol (2011) 0.91
The interactive effect of SIRT1 promoter region polymorphism on type 2 diabetes susceptibility in the North Indian population. PLoS One (2012) 0.91
Role of mitochondria in nonalcoholic fatty liver disease. Int J Mol Sci (2014) 0.91
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Ontogeny and nutritional programming of uncoupling protein-2 and glucocorticoid receptor mRNA in the ovine lung. J Physiol (2005) 0.89
Hormonal regulation of physiological cell turnover and apoptosis. Cell Tissue Res (2000) 0.89
Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism. Arch Toxicol (2015) 0.88
A microRNA-30e/mitochondrial uncoupling protein 2 axis mediates TGF-β1-induced tubular epithelial cell extracellular matrix production and kidney fibrosis. Kidney Int (2013) 0.87
Up-regulation of avian uncoupling protein in cold-acclimated and hyperthyroid ducklings prevents reactive oxygen species production by skeletal muscle mitochondria. BMC Physiol (2010) 0.87
Production of reactive oxygen species by multipotent stromal cells/mesenchymal stem cells upon exposure to fas ligand. Cell Transplant (2012) 0.87
UCP2 modulates cell proliferation through the MAPK/ERK pathway during erythropoiesis and has no effect on heme biosynthesis. J Biol Chem (2008) 0.87
Susceptibility to apoptosis in insulin-like growth factor-I receptor-deficient brown adipocytes. Mol Biol Cell (2004) 0.87
New aspects of mitochondrial Uncoupling Proteins (UCPs) and their roles in tumorigenesis. Int J Mol Sci (2011) 0.87
New aspects of melanocortin signaling: a role for PRCP in α-MSH degradation. Front Neuroendocrinol (2010) 0.87
Role of uncoupling proteins in cancer. Cancers (Basel) (2010) 0.86
Mitochondrial uncoupling protein 2 inhibits mast cell activation and reduces histamine content. J Immunol (2009) 0.86
Endurance training increases stimulation of uncoupling of skeletal muscle mitochondria in humans by non-esterified fatty acids: an uncoupling-protein-mediated effect? Biochem J (2000) 0.86
Characterization of the differential expression of uncoupling protein 2 and ROS production in differentiated mouse macrophage-cells (Mm1) and the progenitor cells (M1). J Mol Histol (2005) 0.86
Mitochondrial reactive oxygen species modulate mosquito susceptibility to Plasmodium infection. PLoS One (2012) 0.86
Genomic structure and expression of uncoupling protein 2 genes in rainbow trout (Oncorhynchus mykiss). BMC Genomics (2006) 0.85
Fatty acid flippase activity of UCP2 is essential for its proton transport in mitochondria. Cell Metab (2014) 0.85
Perspectives on mitochondrial uncoupling proteins-mediated neuroprotection. J Bioenerg Biomembr (2014) 0.85
Quantification of uncoupling protein 2 reveals its main expression in immune cells and selective up-regulation during T-cell proliferation. PLoS One (2012) 0.85
High anoxia tolerance in the subterranean salamander Proteus anguinus without oxidative stress nor activation of antioxidant defenses during reoxygenation. J Comp Physiol B (2009) 0.85
Uncoupling protein-2 up-regulation and enhanced cyanide toxicity are mediated by PPARalpha activation and oxidative stress. Toxicol Appl Pharmacol (2007) 0.84
Oxidative phosphorylation flexibility in the liver of mice resistant to high-fat diet-induced hepatic steatosis. Diabetes (2011) 0.84
Upregulation of UCP2 by adiponectin: the involvement of mitochondrial superoxide and hnRNP K. PLoS One (2012) 0.84
Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus. J Neuroinflammation (2012) 0.84
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Vitamin E succinate enhances steatotic liver energy status and prevents oxidative damage following ischemia/reperfusion. Transplant Proc (2009) 0.83
UCP2 induced by natural birth regulates neuronal differentiation of the hippocampus and related adult behavior. PLoS One (2012) 0.83
UCP2 overexpression worsens mitochondrial dysfunction and accelerates disease progression in a mouse model of amyotrophic lateral sclerosis. Mol Cell Neurosci (2013) 0.82
Mitochondrial uncoupling protein-2 deficiency protects steatotic mouse hepatocytes from hypoxia/reoxygenation. Am J Physiol Gastrointest Liver Physiol (2011) 0.82
Uncoupling Protein 2 Increases Susceptibility to Lipopolysaccharide-Induced Acute Lung Injury in Mice. Mediators Inflamm (2016) 0.81
Mitochondrial oxidative stress is modulated by oleic acid via an epidermal growth factor receptor-dependent activation of glutathione peroxidase. Biochem J (2002) 0.81
Fatty acids do not activate UCP2 in pancreatic beta cells: comparison with UCP1. Pflugers Arch (2008) 0.80
Age-dependent effects of UCP2 deficiency on experimental acute pancreatitis in mice. PLoS One (2014) 0.80
Uncoupling protein-4 (UCP4) increases ATP supply by interacting with mitochondrial Complex II in neuroblastoma cells. PLoS One (2012) 0.80
Proton leak induced by reactive oxygen species produced during in vitro anoxia/reoxygenation in rat skeletal muscle mitochondria. J Bioenerg Biomembr (2006) 0.80
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The role of mitochondrial bioenergetics and reactive oxygen species in coronary collateral growth. Am J Physiol Heart Circ Physiol (2013) 0.80
Mitochondrial uncoupling protein 2 induces cell cycle arrest and necrotic cell death. Metab Syndr Relat Disord (2013) 0.79
Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle. J Lipid Res (2013) 0.79
Differential gene expression in human abdominal aortic aneurysm and aortic occlusive disease. Oncotarget (2015) 0.79
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Identification and characterization of uncoupling protein 4 in fat body and muscle mitochondria from the cockroach Gromphadorhina cocquereliana. J Bioenerg Biomembr (2011) 0.78
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