Living-cell microarrays.

Manipulating biological agents and cells in micro-scale volumes for applications in medicine. Chem Soc Rev (2013) 1.27

MicroSCALE screening reveals genetic modifiers of therapeutic response in melanoma. Sci Signal (2012) 1.13

Block-Cell-Printing for live single-cell printing. Proc Natl Acad Sci U S A (2014) 1.09

Microengineering methods for cell-based microarrays and high-throughput drug-screening applications. Biofabrication (2011) 0.97

Mesenchymal stem cell mechanobiology and emerging experimental platforms. J R Soc Interface (2013) 0.96

Beyond annexin V: fluorescence response of cellular membranes to apoptosis. Cytotechnology (2012) 0.96

Review of microfluidic microbioreactor technology for high-throughput submerged microbiological cultivation. Biomicrofluidics (2013) 0.93

Live mammalian cell arrays. Nat Methods (2013) 0.88

Apoptosis goes on a chip: advances in the microfluidic analysis of programmed cell death. Anal Chem (2011) 0.88

On-chip regeneration of aptasensors for monitoring cell secretion. Lab Chip (2013) 0.86

Analysis of individual molecular events of DNA damage response by flow- and image-assisted cytometry. Methods Cell Biol (2011) 0.86

Micropatterning of Aptamer Beacons to Create Cytokine-Sensing Surfaces. Cell Mol Bioeng (2010) 0.86

Laser printing of three-dimensional multicellular arrays for studies of cell-cell and cell-environment interactions. Tissue Eng Part C Methods (2011) 0.85

Rise of the micromachines: microfluidics and the future of cytometry. Methods Cell Biol (2011) 0.84

Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies. Technology (Singap World Sci) (2015) 0.81

Microfluidics: Emerging prospects for anti-cancer drug screening. World J Clin Oncol (2010) 0.81

Organomatics and organometrics: Novel platforms for long-term whole-organ culture. Technology (Singap World Sci) (2014) 0.79

Living Cell Microarrays: An Overview of Concepts. Microarrays (Basel) (2016) 0.77

Direct assembling methodologies for high-throughput bioscreening. Biotechnol J (2011) 0.77

Contact printing of arrayed microstructures. Anal Bioanal Chem (2010) 0.77

High resolution scanning electron microscopy of cells using dielectrophoresis. PLoS One (2014) 0.77

Spot identification and quality control in cell-based microarrays. ACS Comb Sci (2012) 0.77

Protein Microarrays with Novel Microfluidic Methods: Current Advances. Microarrays (Basel) (2014) 0.75

An open-chamber flow-focusing device for focal stimulation of micropatterned cells. Biomicrofluidics (2016) 0.75

Co-fabrication of chitosan and epoxy photoresist to form microwell arrays with permeable hydrogel bottoms. Biomaterials (2015) 0.75

High-Throughput Toxicity and Phenotypic Screening of 3D Human Neural Progenitor Cell Cultures on a Microarray Chip Platform. Stem Cell Reports (2016) 0.75

A lectin-based cell microarray approach to analyze the mammalian granulosa cell surface glycosylation profile. Glycoconj J (2016) 0.75

Green fluorescent protein as a marker for gene expression. Science (1994) 34.55

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. J Biomol Screen (1999) 32.67

CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol (2006) 32.51

RNA interference. Nature (2002) 22.28

Geometric control of cell life and death. Science (1997) 18.13

Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell (2004) 16.89

CellProfiler: free, versatile software for automated biological image analysis. Biotechniques (2007) 14.71

Monolithic microfabricated valves and pumps by multilayer soft lithography. Science (2000) 14.37

Cellular and molecular mechanisms of fibrosis. J Pathol (2008) 14.01

Improved green fluorescence. Nature (1995) 12.65

Soft lithography in biology and biochemistry. Annu Rev Biomed Eng (2001) 11.36

Visualizing spatiotemporal dynamics of multicellular cell-cycle progression. Cell (2008) 10.49

Socializing with the neighbors: stem cells and their niche. Cell (2004) 9.40

Oscillations in NF-kappaB signaling control the dynamics of gene expression. Science (2004) 8.44

Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature (2003) 7.80

The stem-cell niche as an entity of action. Nature (2006) 7.73

Microfluidic large-scale integration. Science (2002) 7.64

A microfluidic culture platform for CNS axonal injury, regeneration and transport. Nat Methods (2005) 7.62

Physics and applications of microfluidics in biology. Annu Rev Biomed Eng (2002) 5.90

Development and use of fluorescent protein markers in living cells. Science (2003) 5.47

Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device. Nat Biotechnol (2002) 5.37

Generation of destabilized green fluorescent protein as a transcription reporter. J Biol Chem (1998) 5.22

Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue. Nature (2004) 5.09

Microarrays of cells expressing defined cDNAs. Nature (2001) 5.05

Plasma membrane channels formed by connexins: their regulation and functions. Physiol Rev (2003) 4.87

High-throughput RNAi screening by time-lapse imaging of live human cells. Nat Methods (2006) 4.86

Microscale culture of human liver cells for drug development. Nat Biotechnol (2007) 4.85

High-throughput screening assays for the identification of chemical probes. Nat Chem Biol (2007) 4.50

An extracellular matrix microarray for probing cellular differentiation. Nat Methods (2005) 4.35

Physicochemical modelling of cell signalling pathways. Nat Cell Biol (2006) 4.34

Pathogenic bacteria induce aversive olfactory learning in Caenorhabditis elegans. Nature (2005) 4.30

Effect of cell-cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells. FASEB J (1999) 4.22

Receptor-mediated activation of heterotrimeric G-proteins in living cells. Science (2001) 4.04

Image-based multivariate profiling of drug responses from single cells. Nat Methods (2007) 3.90

Electrical forces for microscale cell manipulation. Annu Rev Biomed Eng (2006) 3.71

Cadherins as modulators of cellular phenotype. Annu Rev Cell Dev Biol (2003) 3.67

The response of human epithelial cells to TNF involves an inducible autocrine cascade. Cell (2006) 3.57

Keratinocyte-fibroblast interactions in wound healing. J Invest Dermatol (2007) 3.51

Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection. Science (2005) 3.49

Dynamic single cell culture array. Lab Chip (2006) 3.46

"Fluorescent timer": protein that changes color with time. Science (2000) 3.42

Microengineering of cellular interactions. Annu Rev Biomed Eng (2000) 3.31

Genome-wide RNAi screen for host factors required for intracellular bacterial infection. Science (2005) 3.28

Automatic identification of subcellular phenotypes on human cell arrays. Genome Res (2004) 3.25

Probing the role of multicellular organization in three-dimensional microenvironments. Nat Methods (2006) 3.20

Versatile, fully automated, microfluidic cell culture system. Anal Chem (2007) 3.19

Data-driven modelling of signal-transduction networks. Nat Rev Mol Cell Biol (2006) 3.18

Mechanotransduction at cell-matrix and cell-cell contacts. Annu Rev Biomed Eng (2004) 3.15

High-throughput fluorescence microscopy for systems biology. Nat Rev Mol Cell Biol (2006) 3.08

Dynamics of Drosophila embryonic patterning network perturbed in space and time using microfluidics. Nature (2005) 3.01

Systematic genome-wide screens of gene function. Nat Rev Genet (2004) 2.92

Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Genes Dev (2003) 2.76

AN ADDITION TO THE TECHNIQUE OF THE CULTIVATION OF TISSUES IN VITRO. J Exp Med (1911) 2.74

RNAi living-cell microarrays for loss-of-function screens in Drosophila melanogaster cells. Nat Methods (2004) 2.72

Microfluidic control of cell pairing and fusion. Nat Methods (2009) 2.58

Large-scale single-cell trapping and imaging using microwell arrays. Anal Chem (2005) 2.58

Fluorescent protein spectra. J Cell Sci (2001) 2.49

Morphogenetic cell movements: diversity from modular mechanical properties. Science (2008) 2.45

Imaging protein kinase Calpha activation in cells. Science (1999) 2.37

Dynamic single-cell analysis for quantitative biology. Anal Chem (2006) 2.36

Emergence of patterned stem cell differentiation within multicellular structures. Stem Cells (2008) 2.34

Single-cell enzyme concentrations, kinetics, and inhibition analysis using high-density hydrodynamic cell isolation arrays. Anal Chem (2006) 2.28

Mechanical control of tissue morphogenesis during embryological development. Int J Dev Biol (2006) 2.24

Microarrays of lentiviruses for gene function screens in immortalized and primary cells. Nat Methods (2006) 2.18

Fluorescence proteins, live-cell imaging, and mechanobiology: seeing is believing. Annu Rev Biomed Eng (2008) 2.16

Reverse transfection on cell arrays for high content screening microscopy. Nat Protoc (2007) 2.09

Determination of cell fate selection during phage lambda infection. Proc Natl Acad Sci U S A (2008) 2.05

Cell patterning chip for controlling the stem cell microenvironment. Biomaterials (2007) 2.04

Controlling cell interactions by micropatterning in co-cultures: hepatocytes and 3T3 fibroblasts. J Biomed Mater Res (1997) 2.00

A high-throughput microfluidic real-time gene expression living cell array. Lab Chip (2006) 1.93

Exploring the regulation of human neural precursor cell differentiation using arrays of signaling microenvironments. Mol Syst Biol (2006) 1.90

Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients. Lab Chip (2005) 1.86

Reporting data from high-throughput screening of small-molecule libraries. Nat Chem Biol (2007) 1.79

Lateral propagation of EGF signaling after local stimulation is dependent on receptor density. Dev Cell (2002) 1.74

A microfabrication-based dynamic array cytometer. Anal Chem (2002) 1.74

Imaging into the future: visualizing gene expression and protein interactions with fluorescent proteins. Nat Cell Biol (2002) 1.74

Image-based chemical screening. Nat Chem Biol (2007) 1.72

Cell-cell signaling by direct contact increases cell proliferation via a PI3K-dependent signal. FEBS Lett (2002) 1.70

Microfluidic arrays for logarithmically perfused embryonic stem cell culture. Lab Chip (2006) 1.69

Building and breeding molecules to spy on cells and tumors. FEBS Lett (2005) 1.64

Cell microarrays and RNA interference chip away at gene function. Nat Genet (2005) 1.56

High-resolution video monitoring of hematopoietic stem cells cultured in single-cell arrays identifies new features of self-renewal. Proc Natl Acad Sci U S A (2006) 1.56

Dynamic gene expression profiling using a microfabricated living cell array. Anal Chem (2004) 1.50

Microarrays of small molecules embedded in biodegradable polymers for use in mammalian cell-based screens. Proc Natl Acad Sci U S A (2004) 1.48

Adhesion remodeling underlying tissue morphogenesis. Trends Cell Biol (2005) 1.48

Photo- and electropatterning of hydrogel-encapsulated living cell arrays. Lab Chip (2004) 1.46

Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices. Anal Chem (2007) 1.45

Managing evaporation for more robust microscale assays. Part 1. Volume loss in high throughput assays. Lab Chip (2008) 1.44

The potential of high-content high-throughput microscopy in drug discovery. Br J Pharmacol (2007) 1.42

High-throughput microfluidics: improved sample treatment and washing over standard wells. Lab Chip (2007) 1.40

High-density microfluidic arrays for cell cytotoxicity analysis. Lab Chip (2007) 1.34

RNA interference microarrays: high-throughput loss-of-function genetics in mammalian cells. Proc Natl Acad Sci U S A (2004) 1.29

Cell-biological applications of transfected-cell microarrays. Trends Cell Biol (2002) 1.28

Probing heterotypic cell interactions: hepatocyte function in microfabricated co-cultures. J Biomater Sci Polym Ed (1998) 1.26

Nanoliter scale microbioreactor array for quantitative cell biology. Biotechnol Bioeng (2006) 1.24

Managing evaporation for more robust microscale assays. Part 2. Characterization of convection and diffusion for cell biology. Lab Chip (2008) 1.24

In vitro zonation and toxicity in a hepatocyte bioreactor. Toxicol Sci (2004) 1.24

Microfluidic flow-encoded switching for parallel control of dynamic cellular microenvironments. Lab Chip (2007) 1.23

Exploring interactions between rat hepatocytes and nonparenchymal cells using gene expression profiling. Hepatology (2004) 1.20

A plate reader-compatible microchannel array for cell biology assays. Lab Chip (2007) 1.17

Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure. Nat Biotechnol (2012) 1.74

Dynamic gene expression profiling using a microfabricated living cell array. Anal Chem (2004) 1.50

DNA-triggered innate immune responses are propagated by gap junction communication. Proc Natl Acad Sci U S A (2009) 1.17

Immunogenicity of protein aggregates--concerns and realities. Int J Pharm (2012) 1.14

Optimization of reporter cells for expression profiling in a microfluidic device. Biomed Microdevices (2005) 1.10

Aggregation and pH-temperature phase behavior for aggregates of an IgG2 antibody. J Pharm Sci (2012) 0.90

High throughput single cell bioinformatics. Biotechnol Prog (2009) 0.87

Development of an in vitro cell culture model of hepatic steatosis using hepatocyte-derived reporter cells. Biotechnol Bioeng (2009) 0.86

High-throughput single cell arrays as a novel tool in biopreservation. Cryobiology (2009) 0.82

The inflammatory response to double stranded DNA in endothelial cells is mediated by NFκB and TNFα. PLoS One (2011) 0.79