Published in Oncogene on April 27, 2009
Cells of origin in cancer. Nature (2011) 6.85
Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. J Clin Oncol (2010) 4.94
Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell (2011) 4.78
Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice. Science (2012) 4.14
Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma. Nat Rev Cancer (2010) 4.10
Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin. J Clin Oncol (2011) 3.23
The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma. Genes Dev (2011) 2.48
Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas. PLoS One (2012) 1.93
Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma. Proc Natl Acad Sci U S A (2011) 1.86
Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype. PLoS One (2011) 1.77
Asymmetry-defective oligodendrocyte progenitors are glioma precursors. Cancer Cell (2011) 1.67
The neurobiology of gliomas: from cell biology to the development of therapeutic approaches. Nat Rev Neurosci (2011) 1.66
PDGF and PDGF receptors in glioma. Ups J Med Sci (2012) 1.43
Genetic modeling of gliomas in mice: new tools to tackle old problems. Glia (2011) 1.28
Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. Cancer Res (2013) 1.23
Candidate pathways for promoting differentiation or quiescence of oligodendrocyte progenitor-like cells in glioma. Cancer Res (2012) 1.15
Intratumoral mediated immunosuppression is prognostic in genetically engineered murine models of glioma and correlates to immunotherapeutic responses. Clin Cancer Res (2010) 1.15
Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain. Nat Cell Biol (2013) 1.03
Differential expression of 2',3'-cyclic-nucleotide 3'-phosphodiesterase and neural lineage markers correlate with glioblastoma xenograft infiltration and patient survival. Clin Cancer Res (2012) 1.03
The cellular origin for malignant glioma and prospects for clinical advancements. Expert Rev Mol Diagn (2012) 1.02
Glioblastoma-initiating cells: relationship with neural stem cells and the micro-environment. Cancers (Basel) (2013) 1.01
Production of avian retroviruses and tissue-specific somatic retroviral gene transfer in vivo using the RCAS/TVA system. Nat Protoc (2012) 0.96
Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process. Proc Natl Acad Sci U S A (2014) 0.95
Transcriptional differences between normal and glioma-derived glial progenitor cells identify a core set of dysregulated genes. Cell Rep (2013) 0.93
miRNA-21 is developmentally regulated in mouse brain and is co-expressed with SOX2 in glioma. BMC Cancer (2012) 0.92
Seeing is believing: are cancer stem cells the Loch Ness monster of tumor biology? Stem Cell Rev (2011) 0.92
On the origin of glioma. Ups J Med Sci (2012) 0.92
Developmental origins of brain tumors. Curr Opin Neurobiol (2012) 0.89
Brain stem cells as the cell of origin in glioma. World J Stem Cells (2014) 0.88
Contribution of tumor heterogeneity in a new animal model of CNS tumors. Mol Cancer Res (2014) 0.88
The bright and the dark sides of DNA repair in stem cells. J Biomed Biotechnol (2010) 0.87
Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12. PLoS One (2011) 0.86
Novel Perspectives on p53 Function in Neural Stem Cells and Brain Tumors. J Oncol (2010) 0.86
Gliomagenesis and the use of neural stem cells in brain tumor treatment. Anticancer Agents Med Chem (2010) 0.86
Cell of origin for malignant gliomas and its implication in therapeutic development. Cold Spring Harb Perspect Biol (2015) 0.85
Complex oncogenic signaling networks regulate brain tumor-initiating cells and their progenies: pivotal roles of wild-type EGFR, EGFRvIII mutant and hedgehog cascades and novel multitargeted therapies. Brain Pathol (2011) 0.82
The probable cell of origin of NF1- and PDGF-driven glioblastomas. PLoS One (2011) 0.81
Regulation of stem cell plasticity: mechanisms and relevance to tissue biology and cancer. Mol Ther (2012) 0.81
NG2-expressing glial precursor cells are a new potential oligodendroglioma cell initiating population in N-ethyl-N-nitrosourea-induced gliomagenesis. Carcinogenesis (2010) 0.81
What underlies the diversity of brain tumors? Cancer Metastasis Rev (2013) 0.81
Signal transducer and activator of transcription 5b drives malignant progression in a PDGFB-dependent proneural glioma model by suppressing apoptosis. Int J Cancer (2014) 0.80
Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance. Stem Cells Int (2016) 0.80
Imaging the microanatomy of astrocyte-T-cell interactions in immune-mediated inflammation. Front Cell Neurosci (2013) 0.80
Review: insights gained from modelling high-grade glioma in the mouse. Neuropathol Appl Neurobiol (2012) 0.80
The taxonomy of brain cancer stem cells: what's in a name? Oncoscience (2014) 0.79
Oncogene interactions are required for glioma development and progression as revealed by a tissue specific transgenic mouse model. Chin J Cancer (2011) 0.79
Platelet-derived growth factor in glioblastoma-driver or biomarker? Ups J Med Sci (2014) 0.79
Signals that regulate the oncogenic fate of neural stem cells and progenitors. Exp Neurol (2013) 0.79
BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells. Mol Cancer Res (2013) 0.79
Oligodendrocyte/type-2 astrocyte progenitor cells and glial-restricted precursor cells generate different tumor phenotypes in response to the identical oncogenes. J Neurosci (2013) 0.78
Histidine-rich glycoprotein can prevent development of mouse experimental glioblastoma. PLoS One (2009) 0.78
Glial progenitors as targets for transformation in glioma. Adv Cancer Res (2014) 0.78
ASYMMETRIC CELL DIVISION: IMPLICATIONS FOR GLIOMA DEVELOPMENT AND TREATMENT. Transl Neurosci (2013) 0.77
NG2 glia are required for vessel network formation during embryonic development. Elife (2015) 0.77
Isolation, cultivation and identification of brain glioma stem cells by magnetic bead sorting. Neural Regen Res (2012) 0.77
In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies. Cell Mol Life Sci (2014) 0.76
MADM gives new insights into gliomagenesis. J Mol Cell Biol (2011) 0.76
Intrinsic astrocyte heterogeneity influences tumor growth in glioma mouse models. Brain Pathol (2016) 0.76
PDGF activation in PGDS-positive arachnoid cells induces meningioma formation in mice promoting tumor progression in combination with Nf2 and Cdkn2ab loss. Oncotarget (2015) 0.75
Culture conditions tailored to the cell of origin are critical for maintaining native properties and tumorigenicity of glioma cells. Neuro Oncol (2016) 0.75
The Microenvironment in Gliomas: Phenotypic Expressions. Cancers (Basel) (2015) 0.75
Double minute amplification of mutant PDGF receptor α in a mouse glioma model. Sci Rep (2015) 0.75
The Crossroads of Neural Stem Cell Development and Tumorigenesis. Opera Med Physiol (2016) 0.75
Culture conditions defining glioblastoma cells behavior: what is the impact for novel discoveries? Oncotarget (2017) 0.75
Work satisfaction of general practitioners and the quality of patient care. Fam Pract (1985) 3.78
Quality judgements by patients on general practice care: a literature analysis. Soc Sci Med (1994) 2.08
A novel function of the transforming domain of E1a: repression of AP-1 activity. Cell (1990) 1.97
Guidelines on management of low-grade gliomas: report of an EFNS-EANO Task Force. Eur J Neurol (2010) 1.85
Myeloperoxidase-mediated iodination in granulocytes. Scand J Haematol (1972) 1.83
Indicators of the quality of general practice care of patients with chronic illness: a step towards the real involvement of patients in the assessment of the quality of care. Qual Health Care (1996) 1.79
A novel and cytogenetically cryptic t(7;21)(p22;q22) in acute myeloid leukemia results in fusion of RUNX1 with the ubiquitin-specific protease gene USP42. Leukemia (2006) 1.60
Rapid antibody test for diagnosing fragile X syndrome: a validation of the technique. Hum Genet (1997) 1.59
Altered density, metabolism and surface receptors of eosinophils in eosinophilia. Immunology (1982) 1.53
Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status. Leukemia (2007) 1.52
Risk factors for stroke-related pain 1 year after first-ever stroke. Eur J Neurol (2008) 1.50
Clinical utility of immunoglobulin heavy chain gene rearrangement identification for tumour cell detection in multiple myeloma. Br J Haematol (1998) 1.42
Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma. Oncogene (2007) 1.41
Surgical morbidity and clinical outcomes in ovarian cancer - the role of obesity. BJOG (2016) 1.41
Platelet-derived growth factor is angiogenic in vivo. Growth Factors (1992) 1.40
Serum myeloperoxidase and lactoferrin in neutropenia. Scand J Haematol (1977) 1.25
Characterization of an imatinib-sensitive subset of high-grade human glioma cultures. Oncogene (2006) 1.19
Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines. Oncogene (2009) 1.18
Community HIV/AIDS teams. Health Trends (1991) 1.16
Fusion of the BCR and the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: the first fusion gene involving BCR but not ABL. Genes Chromosomes Cancer (2001) 1.09
A secreted proform of neutrophil proteinase 3 regulates the proliferation of granulopoietic progenitor cells. Blood (1999) 1.06
Urinary incontinence in women and the effects on their lives. Scand J Prim Health Care (1992) 1.05
New polymorphic DNA marker close to the fragile site FRAXA. Genomics (1990) 1.05
Introduction of an N-glycosylation site increases secretion of heterologous proteins in yeasts. Appl Environ Microbiol (2000) 1.05
Evaluation of general practice care by chronically ill patients: effect of the method of administration. Fam Pract (1996) 1.03
Myeloperoxidase-mediated extracellular iodination during phagocytosis in granulocytes. Scand J Haematol (1974) 1.02
MR imaging characteristics and neuropathology of the spinal cord in adult-onset autosomal dominant leukodystrophy with autonomic symptoms. AJNR Am J Neuroradiol (2008) 1.01
Intestinal methanogenesis in primates--a genetic and evolutionary approach. Dtsch Tierarztl Wochenschr (1995) 1.01
Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients. Leukemia (2013) 1.00
Expression of transforming-growth-factor (TGF)-beta receptors and Smad proteins in glioblastoma cell lines with distinct responses to TGF-beta1. Int J Cancer (1999) 0.97
Mechanisms for eosinophil degranulation; release of the eosinophil cationic protein. Immunology (1984) 0.96
Granulopoiesis in chronic myeloid leukemia. II. serial cloning of blood and bone marrow cells in agar culture. Blood (1976) 0.96
Noninvasive test for fragile X syndrome, using hair root analysis. Am J Hum Genet (1999) 0.95
Serum and plasma myeloperoxidase, elastase and lactoferrin content in acute myeloid leukaemia. Scand J Haematol (1979) 0.94
Characterization of mononuclear blood cell-derived differentiation inducing factors for the human promyelocytic leukemia cell line HL-60. J Natl Cancer Inst (1981) 0.93
Platelet-derived growth factor promotes survival of rat and human mesencephalic dopaminergic neurons in culture. Exp Brain Res (1993) 0.93
Snail depletes the tumorigenic potential of glioblastoma. Oncogene (2013) 0.93
Separation of human bone marrow cells in density gradients of polyvinylpyrrolidone coated silica gel (Percoll). Scand J Haematol (1980) 0.92
PROX1 is a predictor of survival for gliomas WHO grade II. Br J Cancer (2011) 0.91
Induction of differentiation in a human promyelocytic leukemic cell line (HL-60). Production of granule proteins. Exp Cell Res (1981) 0.90
A familial case of renal cell carcinoma and a t(2;3) chromosome translocation. Kidney Int (1998) 0.90
Positron emission tomography (11)C-methionine and survival in patients with low-grade gliomas. Cancer (2001) 0.90
Deregulation of the Wilms' tumour gene 1 protein (WT1) by BCR/ABL1 mediates resistance to imatinib in human leukaemia cells. Leukemia (2007) 0.88
Cytokine regulation of GM-CSF and G-CSF secretion by human umbilical cord vein endothelial cells (HUVEC). Cytokine (1996) 0.88
Altered expression of the retinoblastoma tumor-suppressor gene in leukemic cell lines inhibits induction of differentiation but not G1-accumulation. Blood (1997) 0.88
Pharmacokinetics of intravenous ketorolac following caesarean delivery. Int J Obstet Anesth (2012) 0.87
Toxic effects of benzene and benzene metabolites on granulopoietic stem cells and bone marrow cellularity in mice. Toxicol Appl Pharmacol (1981) 0.86
Intraspecific isozyme polymorphism of Anopheles gambiae in relation to environment, behavior, and malaria transmission in southwestern Burkina Faso. Am J Trop Med Hyg (1998) 0.85
Myeloperoxidase and lactoferrin of blood neutrophils and plasma in chronic granulocytic leukaemia. Scand J Haematol (1977) 0.85
Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence. Oncogene (2009) 0.85
Molecular analysis of a familial case of renal cell cancer and a t(3;6)(q12;q15). Genes Chromosomes Cancer (2001) 0.85
Renal cell cancer: chromosome 3 translocations as risk factors. J Natl Cancer Inst (1999) 0.84
Detection of TP53 gene mutation in human meningiomas: a study using immunohistochemistry, polymerase chain reaction/single-strand conformation polymorphism and DNA sequencing techniques on paraffin-embedded samples. Int J Cancer (1995) 0.84
Granulocyte function in chronic granulocytic leukaemia. I. Bactericidal and metabolic capabilities during phagocytosis in isolated granulocytes. Br J Haematol (1975) 0.84
Mechanism of benzene toxicity. Effects of benzene and benzene metabolites on bone marrow cellularity, number of granulopoietic stem cells and frequency of micronuclei in mice. Chem Biol Interact (1982) 0.84
Wilms' tumor gene 1 protein represses the expression of the tumor suppressor interferon regulatory factor 8 in human hematopoietic progenitors and in leukemic cells. Leukemia (2010) 0.84
Multipoint linkage analysis of DXS369 and DXS304 in fragile X families. Am J Med Genet (1991) 0.84
Pyoderma gangrenosum associated with regional enteritis. Improvement in defective granulocyte function and healing of skin lesions during administration of clofazimine. Acta Med Scand (1977) 0.84
Assessing the symptoms, anxiety and practical needs of HIV/AIDS patients receiving palliative care. Qual Life Res (1992) 0.83
At least nine cases of trisomy 11q23-->qter in one generation as a result of familial t(11;13) translocation. J Med Genet (1997) 0.83
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) secretion by adherent monocytes measured by quantitative immunoassays. Eur J Haematol (1992) 0.82
Suppression of normal granulopoiesis in vitro by a leukemia-associated inhibitor (LAI) of acute and chronic leukemia. Blood (1980) 0.82
Molecular genetic and epigenetic analysis of NCX2/SLC8A2 at 19q13.3 in human gliomas. Neuropathol Appl Neurobiol (2010) 0.82
Serum ferritin in the elderly. Scand J Clin Lab Invest (1980) 0.81
Suppression of normal granulopoiesis in vitro by a leukemia associated inhibitor (LAI) derived from a human promyelocytic cell line [HL-60]. Leuk Res (1980) 0.81
A PDGFRA promoter polymorphism, which disrupts the binding of ZNF148, is associated with primitive neuroectodermal tumours and ependymomas. J Med Genet (2005) 0.81
Establishment and phenotypic characterization of human U937 cells with inducible P210 BCR/ABL expression reveals upregulation of CEACAM1 (CD66a). Leukemia (2004) 0.81
New distal marker closely linked to the fragile X locus. Hum Genet (1991) 0.81
Carbohydrate groups of alpha1-microglobulin are important for secretion and tissue localization but not for immunological properties. Glycobiology (2000) 0.80
The prognostic significance of in vitro bone marrow growth pattern in acute non-lymphocytic leukaemia. Scand J Haematol (1981) 0.80
Granulopoiesis in chronic myeloid leukaemia. I. In vitro cloning of blood and bone marrow cells in agar culture. Scand J Haematol (1974) 0.80
Evaluation of the Gurd test for fat embolism. J Bone Joint Surg Br (1974) 0.80
Paracetamol and ketorolac pharmacokinetics and metabolism at delivery and during postpartum. Acta Anaesthesiol Belg (2012) 0.80
Clonal CD5-positive B lymphocytes in myelodysplastic syndrome with systemic vasculitis and trisomy 8. Ann Hematol (1997) 0.79
Epileptic seizures and survival in early disease of grade 2 gliomas. Eur J Neurol (2009) 0.79
Granulocyte interactions with GM-CSF and G-CSF secretion by endothelial cells and monocytes. Eur Cytokine Netw (1999) 0.79
Estradiol and weight are covariates of paracetamol clearance in young women. Gynecol Obstet Invest (2014) 0.78
Purification of human granulocyte catalase in chronic myeloid leukemia. Biochim Biophys Acta (1977) 0.78
Growth factor analysis of low-grade glioma CSF: PDGF and VEGF are not detectable. Neurol Sci (2003) 0.78
Cell production and cell function in human cyclic neutropenia. Scand J Haematol (1975) 0.78
Prognostic value of platelet derived growth factor alpha receptor expression in grade 2 astrocytomas and oligoastrocytomas. J Neurol Neurosurg Psychiatry (2002) 0.78
Receptor for alpha1-microglobulin on T lymphocytes: inhibition of antigen-induced interleukin-2 production. Scand J Immunol (1998) 0.78
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) in serum in bone marrow transplanted patients. Bone Marrow Transplant (1991) 0.78
The Yersinia HPI is present in Serratia liquefaciens isolated from meat. Lett Appl Microbiol (2003) 0.78
IL-10 as an autocrine regulator of CSF secretion by monocytes: disparate effects on GM-CSF and G-CSF secretion. Exp Hematol (1998) 0.78
Quantification of amikacin in bronchial epithelial lining fluid in neonates. Antimicrob Agents Chemother (2011) 0.78
Population pharmacokinetic modelling of total and unbound cefazolin plasma concentrations as a guide for dosing in preterm and term neonates. J Antimicrob Chemother (2014) 0.78
Specific binding and uptake of extracellular nicotinamide in human leukemic K-562 cells. Biochem Pharmacol (1993) 0.77
Effect of bereavement on the health of the remaining family members. Fam Pract (1988) 0.77
Inhibitor of hematopoietic cell proliferation derived from a human leukemic cell line. Blood (1978) 0.77
Biochemical characterization of a leukemia-associated inhibitor (LAI) suppressing normal granulopoiesis in vitro. Blood (1980) 0.77
Myeloid differentiation in liquid cultures of cells from patients with chronic myeloid leukemia: effects of retinoic acid and indomethacin. Exp Hematol (1984) 0.77
The relationship between growth in agar, karyotype and prognosis in acute leukaemia. Scand J Haematol (1984) 0.77
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) in serum during induction treatment of acute leukaemia. Br J Haematol (1991) 0.77
[Somatic fixation. Prevention by the general practitioner]. ZFA (Stuttgart) (1982) 0.77