Published in Curr Opin Neurobiol on May 05, 2012
Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway. Genes Dev (2013) 1.54
Luminal cells are favored as the cell of origin for prostate cancer. Cell Rep (2014) 1.12
The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma. Stem Cells Transl Med (2013) 0.91
Cell of origin for malignant gliomas and its implication in therapeutic development. Cold Spring Harb Perspect Biol (2015) 0.85
Deregulated proliferation and differentiation in brain tumors. Cell Tissue Res (2014) 0.80
It takes two to tango, a dance between the cells of origin and cancer stem cells in the Drosophila larval brain. Semin Cell Dev Biol (2014) 0.79
ASYMMETRIC CELL DIVISION: IMPLICATIONS FOR GLIOMA DEVELOPMENT AND TREATMENT. Transl Neurosci (2013) 0.77
L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration. Mol Cell Biol (2017) 0.75
Rethinking immunotherapy for brain cancers in the light of cancer complexity. Indian J Med Res (2013) 0.75
Culture conditions defining glioblastoma cells behavior: what is the impact for novel discoveries? Oncotarget (2017) 0.75
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell (2010) 39.09
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature (2006) 27.91
Mammalian neural stem cells. Science (2000) 16.09
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell (1999) 15.87
The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol (2002) 8.62
The transcriptional network for mesenchymal transformation of brain tumours. Nature (2009) 8.44
Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron (2011) 8.06
Cells of origin in cancer. Nature (2011) 6.85
CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res (2007) 6.21
Subtypes of medulloblastoma have distinct developmental origins. Nature (2010) 5.94
Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell (2005) 5.51
Mosaic analysis with double markers in mice. Cell (2005) 5.32
Radial glia cells are candidate stem cells of ependymoma. Cancer Cell (2005) 5.21
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell (2002) 5.11
Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells. Cancer Cell (2008) 5.06
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature (2008) 5.00
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell (2009) 4.82
Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell (2011) 4.78
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell (2008) 4.68
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron (2007) 4.47
NG2 cells generate both oligodendrocytes and gray matter astrocytes. Development (2007) 4.21
Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity. Nat Rev Neurosci (2009) 3.72
Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature (2010) 3.70
The origins of medulloblastoma subtypes. Annu Rev Pathol (2008) 3.36
Distinct genetic signatures among pilocytic astrocytomas relate to their brain region origin. Cancer Res (2007) 3.05
The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas. J Neuropathol Exp Neurol (2004) 2.66
Self-renewal does not predict tumor growth potential in mouse models of high-grade glioma. Cancer Cell (2012) 2.50
The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma. Genes Dev (2011) 2.48
Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model. Cancer Cell (2009) 2.14
Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma. Oncogene (2009) 1.96
Non-stem cell origin for oligodendroglioma. Cancer Cell (2010) 1.95
Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics. J Clin Oncol (2006) 1.92
Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype. PLoS One (2011) 1.77
Genetic determinants of malignancy in a mouse model for oligodendroglioma. Cancer Res (2003) 1.46
Modeling sporadic loss of heterozygosity in mice by using mosaic analysis with double markers (MADM). Proc Natl Acad Sci U S A (2007) 1.29
Extensions of MADM (mosaic analysis with double markers) in mice. PLoS One (2012) 1.06
The WHO Classification of Tumours of the Central Nervous System, 4th edition. Arch Pathol Lab Med (2008) 0.98
Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell (2011) 4.78
Development of a method for the purification and culture of rodent astrocytes. Neuron (2011) 1.92
Luminal mitosis drives epithelial cell dispersal within the branching ureteric bud. Dev Cell (2013) 1.79
Genetic mosaic dissection of Lis1 and Ndel1 in neuronal migration. Neuron (2010) 1.58
Site-specific integrase-mediated transgenesis in mice via pronuclear injection. Proc Natl Acad Sci U S A (2011) 1.58
Modeling sporadic loss of heterozygosity in mice by using mosaic analysis with double markers (MADM). Proc Natl Acad Sci U S A (2007) 1.29
Mouse TU tagging: a chemical/genetic intersectional method for purifying cell type-specific nascent RNA. Genes Dev (2013) 1.24
Extensions of MADM (mosaic analysis with double markers) in mice. PLoS One (2012) 1.06
Inflammation and Gliomagenesis: Bi-Directional Communication at Early and Late Stages of Tumor Progression. Curr Pathobiol Rep (2013) 0.79
MADM-ML, a mouse genetic mosaic system with increased clonal efficiency. PLoS One (2013) 0.78
[PCR-mtDNA for detecting components of duck origin in foodstuff and feedstuff]. Sheng Wu Gong Cheng Xue Bao (2008) 0.75
[Detection of bovine, goat, pig and chicken derived ingredients in animal products with universal PCR-microarray method]. Sheng Wu Gong Cheng Xue Bao (2010) 0.75