Published in Biophys J on April 01, 1988
Aspartic acid-96 is the internal proton donor in the reprotonation of the Schiff base of bacteriorhodopsin. Proc Natl Acad Sci U S A (1989) 3.06
Substitution of amino acids Asp-85, Asp-212, and Arg-82 in bacteriorhodopsin affects the proton release phase of the pump and the pK of the Schiff base. Proc Natl Acad Sci U S A (1990) 2.80
Replacement of aspartic acid-96 by asparagine in bacteriorhodopsin slows both the decay of the M intermediate and the associated proton movement. Proc Natl Acad Sci U S A (1989) 2.64
Imaging the membrane protein bacteriorhodopsin with the atomic force microscope. Biophys J (1990) 2.22
Protein dynamics in the bacteriorhodopsin photocycle: submillisecond Fourier transform infrared spectra of the L, M, and N photointermediates. Proc Natl Acad Sci U S A (1991) 1.71
Reversible steps in the bacteriorhodopsin photocycle. Proc Natl Acad Sci U S A (1992) 1.40
Light-induced currents from oriented purple membrane: I. Correlation of the microsecond component (B2) with the L-M photocycle transition. Biophys J (1990) 1.37
Charge motions during the photocycle of pharaonis halorhodopsin. Biophys J (2000) 1.06
Bacteriorhodopsin photocycle at cryogenic temperatures reveals distributed barriers of conformational substates. Proc Natl Acad Sci U S A (2007) 1.02
Electric signals during the bacteriorhodopsin photocycle, determined over a wide pH range. Biophys J (1998) 0.99
Light-induced currents from oriented purple membrane: II. Proton and cation contributions to the photocurrent. Biophys J (1990) 0.98
Nonlinear voltage dependence of the light-driven proton pump current of bacteriorhodopsin. Biophys J (1988) 0.94
Characterization of the proton-transporting photocycle of pharaonis halorhodopsin. Biophys J (2000) 0.92
Photovoltage kinetics of the acid-blue and acid-purple forms of bacteriorhodopsin: evidence for no net charge transfer. Biophys J (1995) 0.91
Evidence for the first phase of the reprotonation switch of bacteriorhodopsin from time-resolved photovoltage and flash photolysis experiments on the photoreversal of the M-intermediate. Biophys J (1997) 0.89
Bacteriorhodopsin expressed in Schizosaccharomyces pombe pumps protons through the plasma membrane. Proc Natl Acad Sci U S A (1993) 0.89
Proton transport by a bacteriorhodopsin mutant, aspartic acid-85-->asparagine, initiated in the unprotonated Schiff base state. Proc Natl Acad Sci U S A (1995) 0.88
Temperature jump study of charge translocation during the bacteriorhodopsin photocycle. Biophys J (1989) 0.87
Intramolecular charge transfer in the bacteriorhodopsin mutants Asp85-->Asn and Asp212-->Asn: effects of pH and anions. Biophys J (1995) 0.86
Influence of an electrical potential on the charge transfer kinetics of bacteriorhodopsin. Biophys J (1990) 0.77
Electrostatic coupling of ion pumps. Biophys J (1992) 0.77
Dynamics of ligand binding to myoglobin. Biochemistry (1975) 17.10
Bacteriorhodopsin and the purple membrane of halobacteria. Biochim Biophys Acta (1979) 9.85
A Fourier method for the analysis of exponential decay curves. Biophys J (1976) 3.83
Fluorescence lifetime distributions in proteins. Biophys J (1987) 3.18
Protein dynamics. Mössbauer spectroscopy on deoxymyoglobin crystals. J Mol Biol (1982) 3.14
Time-resolved photoelectric and absorption signals from oriented purple membranes immobilized in gel. J Biochem Biophys Methods (1985) 2.47
Interpretation of fluorescence decays in proteins using continuous lifetime distributions. Biophys J (1987) 2.30
A model of protein conformational substates. Proc Natl Acad Sci U S A (1985) 2.23
Photoelectric signals from dried oriented purple membranes of Halobacterium halobium. Biophys J (1983) 2.10
Flash-induced volume changes of bacteriorhodopsin-containing membrane fragments and their relationship to proton movements and absorbance transients. J Biol Chem (1978) 1.89
Fast stages of photoelectric processes in biological membranes. I. Bacteriorhodopsin. Eur J Biochem (1981) 1.86
Time resolution of the intermediate steps in the bacteriorhodopsin-linked electrogenesis. FEBS Lett (1978) 1.73
How Many M Forms are there in the Bacteriorhodopsin Photocycle? Biophys J (1986) 1.48
Events in proton pumping by bacteriorhodopsin. Biophys J (1983) 1.37
Temperature dependence of photovoltages generated by bacteriorhodopsin. Biophys J (1985) 1.18
Viscosity scaling and protein dynamics. Biophys Chem (1983) 1.14
Conformational changes in bacteriorhodopsin studied by infrared attenuated total reflection. Biophys J (1987) 0.99
Evidence that charge motion within bacteriorhodopsin depends on solvent viscosity. Photochem Photobiol (1986) 0.97
Direct analysis of continuous relaxation spectra. J Biochem Biophys Methods (1979) 0.85
The exocytotic event in chromaffin cells revealed by patch amperometry. Nature (1997) 3.69
High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism. Nat Cell Biol (1999) 3.40
Aspartic acid-96 is the internal proton donor in the reprotonation of the Schiff base of bacteriorhodopsin. Proc Natl Acad Sci U S A (1989) 3.06
Substitution of amino acids Asp-85, Asp-212, and Arg-82 in bacteriorhodopsin affects the proton release phase of the pump and the pK of the Schiff base. Proc Natl Acad Sci U S A (1990) 2.80
Transient and linear dichroism studies on bacteriorhodopsin: determination of the orientation of the 568 nm all-trans retinal chromophore. J Mol Biol (1977) 2.75
Replacement of aspartic acid-96 by asparagine in bacteriorhodopsin slows both the decay of the M intermediate and the associated proton movement. Proc Natl Acad Sci U S A (1989) 2.64
Binding of all-trans-retinal to the purple membrane. Evidence for cooperativity and determination of the extinction coefficient. Biochemistry (1979) 2.27
Determination of lipid order parameters and rotational correlation times from fluorescence depolarization experiments. FEBS Lett (1979) 2.17
A natural CD label to probe the structure of the purple membrane from Halobacterium halobium by means of exciton coupling effects. Biochem Biophys Res Commun (1975) 1.90
IgE-mediated degranulation of mast cells does not require opening of ion channels. Nature (1986) 1.87
Formation and properties of bacteriorhodopsin monomers in the non-ionic detergents octyl-beta-D-glucoside and Triton X-100. FEBS Lett (1978) 1.78
Rapid long-range proton diffusion along the surface of the purple membrane and delayed proton transfer into the bulk. Proc Natl Acad Sci U S A (1995) 1.77
Bacteriorhodopsin monomers pump protons. FEBS Lett (1979) 1.69
The exocytotic fusion pore of small granules has a conductance similar to an ion channel. J Cell Biol (1995) 1.63
Evidence for chromophore-chromophore interactions in the purple membrane from reconstitution experiments of the chromophore-free membrane. Biophys Struct Mech (1976) 1.49
A patch-clamp study of histamine-secreting cells. J Gen Physiol (1986) 1.44
The retinylidene Schiff base counterion in bacteriorhodopsin. J Biol Chem (1991) 1.42
Exo-endocytosis and closing of the fission pore during endocytosis in single pituitary nerve terminals internally perfused with high calcium concentrations. Proc Natl Acad Sci U S A (1994) 1.42
Bacteriorhodopsin mutants containing single substitutions of serine or threonine residues are all active in proton translocation. J Biol Chem (1991) 1.41
Expression of the bacterioopsin gene in Halobacterium halobium using a multicopy plasmid. Proc Natl Acad Sci U S A (1991) 1.37
Lipid--protein interactions in bacteriorhodopsin--dimyristoylphosphatidylcholine vesicles. Biochemistry (1981) 1.32
The dynamics of exocytosis in human neutrophils. J Cell Biol (1988) 1.31
A neutron diffraction study on the location of the polyene chain of retinal in bacteriorhodopsin. Proc Natl Acad Sci U S A (1985) 1.31
ATP-induced pore formation in the plasma membrane of rat peritoneal mast cells. J Gen Physiol (1990) 1.29
Focal exocytosis by eosinophils--compound exocytosis and cumulative fusion. EMBO J (1993) 1.28
Fusion pore expansion in horse eosinophils is modulated by Ca2+ and protein kinase C via distinct mechanisms. EMBO J (1998) 1.24
Resolution of patch capacitance recordings and of fusion pore conductances in small vesicles. Biophys J (2000) 1.19
Surface charge of bacteriorhodopsin detected with covalently bound pH indicators at selected extracellular and cytoplasmic sites. Biochemistry (1994) 1.18
Photochemical cycle and light-dark adaptation of monomeric and aggregated bacteriorhodopsin in various lipid environments. Biochemistry (1983) 1.17
Calorimetric and fluorescence depolarization studies on the lipid phase transition of bacteriorhodopsin--dimyristoylphosphatidylcholine vesicles. Biochemistry (1981) 1.17
Individual differences in vowel production. J Acoust Soc Am (1993) 1.13
Location of the cyclohexene ring of the chromophore of bacteriorhodopsin by neutron diffraction with selectively deuterated retinal. Proc Natl Acad Sci U S A (1986) 1.13
Covalently bound pH-indicator dyes at selected extracellular or cytoplasmic sites in bacteriorhodopsin. 1. Proton migration along the surface of bacteriorhodopsin micelles and its delayed transfer from surface to bulk. Biochemistry (1994) 1.13
A novel Ca(2+)-dependent step in exocytosis subsequent to vesicle fusion. FEBS Lett (1995) 1.12
Light-induced proton release and proton uptake reactions in the cyanobacterial phytochrome Cph1. Biochemistry (2001) 1.12
Transmembranous incorporation of photoelectrically active bacteriorhodopsin in planar lipid bilayers. Proc Natl Acad Sci U S A (1981) 1.11
Light-induced isomerization causes an increase in the chromophore tilt in the M intermediate of bacteriorhodopsin: a neutron diffraction study. Proc Natl Acad Sci U S A (1994) 1.09
Transmembrane location of retinal in bacteriorhodopsin by neutron diffraction. Biochemistry (1990) 1.09
Pittsburgh compound-B and Alzheimer's disease biomarkers in CSF, plasma and urine: An exploratory study. Dement Geriatr Cogn Disord (2010) 1.04
Intracellular application of guanosine-5'-O-(3-thiotriphosphate) induces exocytotic granule fusion in guinea pig eosinophils. J Exp Med (1990) 1.03
Anion binding to the Schiff base of the bacteriorhodopsin mutants Asp-85----Asn/Asp-212----Asn and Arg-82----Gln/Asp-85----Asn/Asp-212----Asn. J Biol Chem (1992) 1.02
Influence of conductance changes on patch clamp capacitance measurements using a lock-in amplifier and limitations of the phase tracking technique. Biophys J (1995) 1.02
Capacitance flickers and pseudoflickers of small granules, measured in the cell-attached configuration. Biophys J (1998) 1.02
Fluorescence energy transfer from diphenylhexatriene to bacteriorhodopsin in lipid vesicles. Biophys J (1983) 1.01
Re-orientation of retinal in the M-photointermediate of bacteriorhodopsin. Nat Struct Biol (1995) 0.99
Rotational diffusion and exciton coupling of bacteriorhodopsin in the cell membrane of Halobacterium halobium. FEBS Lett (1977) 0.99
Emotion work and job stressors and their effects on burnout. Psychol Health (2001) 0.99
Between the ground- and M-state of bacteriorhodopsin the retinal transition dipole moment tilts out of the plane of the membrane by only 3 degrees. FEBS Lett (1991) 0.98
Intracellular stimulation of mast cells with guanine nucleotides mimic antigenic stimulation. FEBS Lett (1987) 0.98
Thermal equilibration between the M and N intermediates in the photocycle of bacteriorhodopsin. Biophys J (1993) 0.98
Mechanism of peptide-induced mast cell degranulation. Translocation and patch-clamp studies. J Gen Physiol (1998) 0.97
Evidence for long range allosteric interactions between the extracellular and cytoplasmic parts of bacteriorhodopsin from the mutant R82A and its second site revertant R82A/G231C. J Biol Chem (2000) 0.97
Quasi-elastic light scattering from migrating chemotactic bands of Escherichia coli. Biophys J (1978) 0.97
A bacteriorhodopsin analog reconstituted with a nonisomerizable 13-trans retinal derivative displays light insensitivity. J Biol Chem (1992) 0.96
Distorted structure of the retinal chromophore in bacteriorhodopsin resolved by 2H-NMR. Biochemistry (1994) 0.96
Lateral segregation of proteins induced by cholesterol in bacteriorhodopsin-phospholipid vesicles. Biochim Biophys Acta (1980) 0.96
Robust, high-resolution, whole cell patch-clamp capacitance measurements using square wave stimulation. Biophys J (2001) 0.94
Nonlinear voltage dependence of the light-driven proton pump current of bacteriorhodopsin. Biophys J (1988) 0.94
Exocytosis of catecholamine (CA)-containing and CA-free granules in chromaffin cells. J Biol Chem (2001) 0.94
Consequences of amino acid insertions and/or deletions in transmembrane helix C of bacteriorhodopsin. Proc Natl Acad Sci U S A (1992) 0.94
Regulation of granule size in human and horse eosinophils by number of fusion events among unit granules. J Physiol (1995) 0.93
Photovoltage kinetics of the acid-blue and acid-purple forms of bacteriorhodopsin: evidence for no net charge transfer. Biophys J (1995) 0.91
Spatio-temporal structure of migrating chemotactic band of Escherichia coli. I. Traveling band profile. Biophys J (1979) 0.91
Membrane capacitance techniques to monitor granule exocytosis in neutrophils. J Immunol Methods (1999) 0.91
Structure determination of the cyclohexene ring of retinal in bacteriorhodopsin by solid-state deuterium NMR. Biochemistry (1992) 0.91
Evidence for the first phase of the reprotonation switch of bacteriorhodopsin from time-resolved photovoltage and flash photolysis experiments on the photoreversal of the M-intermediate. Biophys J (1997) 0.89
Light-induced changes in the structure and accessibility of the cytoplasmic loops of rhodopsin in the activated MII state. Biochemistry (2002) 0.89
Rhythmic opening and closing of vesicles during constitutive exo- and endocytosis in chromaffin cells. EMBO J (2000) 0.88
Proton transport by a bacteriorhodopsin mutant, aspartic acid-85-->asparagine, initiated in the unprotonated Schiff base state. Proc Natl Acad Sci U S A (1995) 0.88
Location of chemically modified lysine 41 in the structure of bacteriorhodopsin by neutron diffraction. Biophys J (1986) 0.86
Chromophore orientation in bacteriorhodopsin determined from the angular dependence of deuterium nuclear magnetic resonance spectra of oriented purple membranes. Biochemistry (1998) 0.86
The calcium signal in human neutrophils and its relation to exocytosis investigated by patch-clamp capacitance and Fura-2 measurements. Cell Calcium (1993) 0.86
Intramolecular charge transfer in the bacteriorhodopsin mutants Asp85-->Asn and Asp212-->Asn: effects of pH and anions. Biophys J (1995) 0.86
GTP gamma S-induced calcium transients and exocytosis in human neutrophils. Biosci Rep (1990) 0.85
Time-resolved surface charge change on the cytoplasmic side of bacteriorhodopsin. FEBS Lett (1995) 0.85
Covalent labeling of functional states of the acetylcholine receptor. Effects of antagonists on the receptor conformation. Eur J Biochem (1985) 0.84
X-ray diffraction of a cysteine-containing bacteriorhodopsin mutant and its mercury derivative. Localization of an amino acid residue in the loop of an integral membrane protein. Biochemistry (1993) 0.84
Effect of introducing different carboxylate-containing side chains at position 85 on chromophore formation and proton transport in bacteriorhodopsin. J Biol Chem (1992) 0.84
On the origin and the signal-shaping mechanism of the fast photosignal in the vertebrate retina. Biophys J (1982) 0.83
Relationship between fusion pore opening and release during mast cell exocytosis studied with patch amperometry. Biochem Soc Trans (2003) 0.83
Kinetics of the light-induced proton translocation associated with the pH-dependent formation of the metarhodopsin I/II equilibrium of bovine rhodopsin. Biochemistry (1998) 0.83
Pathophysiology of itching and sneezing in allergic rhinitis. Swiss Med Wkly (2009) 0.82
Imaging and nanomedicine for diagnosis and therapy in the central nervous system: report of the eleventh annual Blood-Brain Barrier Disruption Consortium meeting. AJNR Am J Neuroradiol (2006) 0.82
Voltage-dependent membrane capacitance in rat pituitary nerve terminals due to gating currents. Biophys J (2001) 0.82
Order and viscosity of membranes: analysis by time-resolved fluorescence depolarization. Methods Enzymol (1989) 0.82
A slowly activating voltage-dependent K+ current in rat pituitary nerve terminals. J Physiol (1996) 0.81
Compound exocytosis and cumulative degranulation by eosinophils and their role in parasite killing. Parasitol Today (1994) 0.81
The angles between the C(1)-, C(5)-, and C(9)-methyl bonds of the retinylidene chromophore and the membrane normal increase in the M intermediate of bacteriorhodopsin: direct determination with solid-state (2)H NMR. Biochemistry (1999) 0.81
Circular dichroism and fluorescence studies on the binding of ligands to the alpha subunit of tryptophan synthase. Biochemistry (1975) 0.81
Sulfur distribution in bacteriorhodopsin from multiple wavelength anomalous diffraction near the sulfur K-edge with synchrotron x-ray radiation. Biophys J (1998) 0.81
Amyloid Abeta40 CSF concentrations correlate to frontal lobe atrophy in frontotemporal dementia. Neuroreport (2000) 0.80
Does consumption of beer, alcohol, and bitter substances affect bitterness perception? Physiol Behav (1996) 0.80
The self-association of ATP: thermodynamics and geometry. Biophys Chem (1975) 0.80
Medical application of photon correlation spectroscopy. Med Res Eng (1977) 0.79
Exocytotic competence and intergranular fusion in cord blood-derived eosinophils during differentiation. Blood (1997) 0.79