Published in Biochemistry on October 30, 1979
Lateral and rotational diffusion of bacteriorhodopsin in lipid bilayers: experimental test of the Saffman-Delbrück equations. Proc Natl Acad Sci U S A (1982) 4.45
Identification of a third rhodopsin-like pigment in phototactic Halobacterium halobium. Proc Natl Acad Sci U S A (1982) 4.38
Optical recording of action potentials in mammalian neurons using a microbial rhodopsin. Nat Methods (2011) 3.31
Self-assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers. Protein Sci (2003) 2.62
Anisotropic rotation of bacteriorhodopsin in lipid membranes. Comparison of theory with experiment. Biophys J (1981) 1.98
Attachment site(s) of retinal in bacteriorhodopsin. Proc Natl Acad Sci U S A (1981) 1.73
The opsin family of proteins. Biochem J (1986) 1.67
Expression of the bop gene cluster of Halobacterium halobium is induced by low oxygen tension and by light. J Bacteriol (1991) 1.51
Light activates rotations of bacteriorhodopsin in the purple membrane. Biophys J (1984) 1.34
A neutron diffraction study on the location of the polyene chain of retinal in bacteriorhodopsin. Proc Natl Acad Sci U S A (1985) 1.31
Peptide-chain secondary structure of bacteriorhodopsin. Biophys J (1983) 1.30
Molecular sorting of lipids by bacteriorhodopsin in dilauroylphosphatidylcholine/distearoylphosphatidylcholine lipid bilayers. Biophys J (1997) 1.22
Overexpression of bacterio-opsin in Escherichia coli as a water-soluble fusion to maltose binding protein: efficient regeneration of the fusion protein and selective cleavage with trypsin. Protein Sci (1996) 1.06
Nonproton ion release by purple membranes exhibits cooperativity as shown by determination of the optical cross-section. Biophys J (1988) 1.06
Immuno-atomic force microscopy of purple membrane. Biophys J (1996) 1.04
Location of an extrinsic label in the primary and tertiary structure of bacteriorhodopsin. Biophys J (1984) 1.00
Electron cryomicroscopy of bacteriorhodopsin vesicles: mechanism of vesicle formation. Biophys J (1998) 0.95
The pink membrane: the stable photoproduct of deionized purple membrane. Biophys J (1987) 0.94
Quantum efficiencies of bacteriorhodopsin photochemical reactions. Biophys J (1990) 0.92
Chromophore interaction in xanthorhodopsin--retinal dependence of salinixanthin binding. Photochem Photobiol (2008) 0.92
Location of platinum binding sites on bacteriorhodopsin by electron diffraction. Proc Natl Acad Sci U S A (1981) 0.90
Amphipol-assisted folding of bacteriorhodopsin in the presence or absence of lipids: functional consequences. Eur Biophys J (2012) 0.84
Switch from conventional to distributed kinetics in the bacteriorhodopsin photocycle. Biochemistry (2008) 0.81
Met-145 is a key residue in the dark adaptation of bacteriorhodopsin homologs. Biophys J (1994) 0.81
bop gene cluster expression in bacteriorhodopsin-overproducing mutants of Halobacterium halobium. J Bacteriol (1994) 0.79
Properties of bacteriorhodopsin derivatives constructed by insertion of an exogenous epitope into extra-membrane loops. EMBO J (1993) 0.78
Binding of alkyl polyglucoside surfactants to bacteriorhodopsin and its relation to protein stability. Biophys J (2008) 0.78
Effect of membrane potential on the conformation of bacteriorhodopsin reconstituted in lipid vesicles. Biophys J (1988) 0.77
Infrared monitoring of interlayer water in stacks of purple membranes. Photochem Photobiol (2009) 0.76
Differential expression of the demosponge (Suberites domuncula) carotenoid oxygenases in response to light: protection mechanism against the self-produced toxic protein (Suberitine). Mar Drugs (2012) 0.75
Bacteriorhodopsin-ZnO hybrid as a potential sensing element for low-temperature detection of ethanol vapour. Beilstein J Nanotechnol (2016) 0.75
Improved protease digestion conditions for membrane protein detection. Electrophoresis (2015) 0.75
Aspartic acid-96 is the internal proton donor in the reprotonation of the Schiff base of bacteriorhodopsin. Proc Natl Acad Sci U S A (1989) 3.06
Substitution of amino acids Asp-85, Asp-212, and Arg-82 in bacteriorhodopsin affects the proton release phase of the pump and the pK of the Schiff base. Proc Natl Acad Sci U S A (1990) 2.80
Transient and linear dichroism studies on bacteriorhodopsin: determination of the orientation of the 568 nm all-trans retinal chromophore. J Mol Biol (1977) 2.75
Replacement of aspartic acid-96 by asparagine in bacteriorhodopsin slows both the decay of the M intermediate and the associated proton movement. Proc Natl Acad Sci U S A (1989) 2.64
Determination of lipid order parameters and rotational correlation times from fluorescence depolarization experiments. FEBS Lett (1979) 2.17
A natural CD label to probe the structure of the purple membrane from Halobacterium halobium by means of exciton coupling effects. Biochem Biophys Res Commun (1975) 1.90
Distributed kinetics of the charge movements in bacteriorhodopsin: evidence for conformational substates. Biophys J (1988) 1.89
Formation and properties of bacteriorhodopsin monomers in the non-ionic detergents octyl-beta-D-glucoside and Triton X-100. FEBS Lett (1978) 1.78
Rapid long-range proton diffusion along the surface of the purple membrane and delayed proton transfer into the bulk. Proc Natl Acad Sci U S A (1995) 1.77
Bacteriorhodopsin monomers pump protons. FEBS Lett (1979) 1.69
Evidence for chromophore-chromophore interactions in the purple membrane from reconstitution experiments of the chromophore-free membrane. Biophys Struct Mech (1976) 1.49
The retinylidene Schiff base counterion in bacteriorhodopsin. J Biol Chem (1991) 1.42
Bacteriorhodopsin mutants containing single substitutions of serine or threonine residues are all active in proton translocation. J Biol Chem (1991) 1.41
Expression of the bacterioopsin gene in Halobacterium halobium using a multicopy plasmid. Proc Natl Acad Sci U S A (1991) 1.37
Lipid--protein interactions in bacteriorhodopsin--dimyristoylphosphatidylcholine vesicles. Biochemistry (1981) 1.32
A neutron diffraction study on the location of the polyene chain of retinal in bacteriorhodopsin. Proc Natl Acad Sci U S A (1985) 1.31
Surface charge of bacteriorhodopsin detected with covalently bound pH indicators at selected extracellular and cytoplasmic sites. Biochemistry (1994) 1.18
Photochemical cycle and light-dark adaptation of monomeric and aggregated bacteriorhodopsin in various lipid environments. Biochemistry (1983) 1.17
Calorimetric and fluorescence depolarization studies on the lipid phase transition of bacteriorhodopsin--dimyristoylphosphatidylcholine vesicles. Biochemistry (1981) 1.17
Location of the cyclohexene ring of the chromophore of bacteriorhodopsin by neutron diffraction with selectively deuterated retinal. Proc Natl Acad Sci U S A (1986) 1.13
Covalently bound pH-indicator dyes at selected extracellular or cytoplasmic sites in bacteriorhodopsin. 1. Proton migration along the surface of bacteriorhodopsin micelles and its delayed transfer from surface to bulk. Biochemistry (1994) 1.13
Light-induced proton release and proton uptake reactions in the cyanobacterial phytochrome Cph1. Biochemistry (2001) 1.12
Transmembranous incorporation of photoelectrically active bacteriorhodopsin in planar lipid bilayers. Proc Natl Acad Sci U S A (1981) 1.11
Light-induced isomerization causes an increase in the chromophore tilt in the M intermediate of bacteriorhodopsin: a neutron diffraction study. Proc Natl Acad Sci U S A (1994) 1.09
Transmembrane location of retinal in bacteriorhodopsin by neutron diffraction. Biochemistry (1990) 1.09
Anion binding to the Schiff base of the bacteriorhodopsin mutants Asp-85----Asn/Asp-212----Asn and Arg-82----Gln/Asp-85----Asn/Asp-212----Asn. J Biol Chem (1992) 1.02
Fluorescence energy transfer from diphenylhexatriene to bacteriorhodopsin in lipid vesicles. Biophys J (1983) 1.01
Re-orientation of retinal in the M-photointermediate of bacteriorhodopsin. Nat Struct Biol (1995) 0.99
Rotational diffusion and exciton coupling of bacteriorhodopsin in the cell membrane of Halobacterium halobium. FEBS Lett (1977) 0.99
Between the ground- and M-state of bacteriorhodopsin the retinal transition dipole moment tilts out of the plane of the membrane by only 3 degrees. FEBS Lett (1991) 0.98
Thermal equilibration between the M and N intermediates in the photocycle of bacteriorhodopsin. Biophys J (1993) 0.98
Evidence for long range allosteric interactions between the extracellular and cytoplasmic parts of bacteriorhodopsin from the mutant R82A and its second site revertant R82A/G231C. J Biol Chem (2000) 0.97
A bacteriorhodopsin analog reconstituted with a nonisomerizable 13-trans retinal derivative displays light insensitivity. J Biol Chem (1992) 0.96
Distorted structure of the retinal chromophore in bacteriorhodopsin resolved by 2H-NMR. Biochemistry (1994) 0.96
Lateral segregation of proteins induced by cholesterol in bacteriorhodopsin-phospholipid vesicles. Biochim Biophys Acta (1980) 0.96
Consequences of amino acid insertions and/or deletions in transmembrane helix C of bacteriorhodopsin. Proc Natl Acad Sci U S A (1992) 0.94
Nonlinear voltage dependence of the light-driven proton pump current of bacteriorhodopsin. Biophys J (1988) 0.94
Photovoltage kinetics of the acid-blue and acid-purple forms of bacteriorhodopsin: evidence for no net charge transfer. Biophys J (1995) 0.91
Structure determination of the cyclohexene ring of retinal in bacteriorhodopsin by solid-state deuterium NMR. Biochemistry (1992) 0.91
Evidence for the first phase of the reprotonation switch of bacteriorhodopsin from time-resolved photovoltage and flash photolysis experiments on the photoreversal of the M-intermediate. Biophys J (1997) 0.89
Light-induced changes in the structure and accessibility of the cytoplasmic loops of rhodopsin in the activated MII state. Biochemistry (2002) 0.89
Proton transport by a bacteriorhodopsin mutant, aspartic acid-85-->asparagine, initiated in the unprotonated Schiff base state. Proc Natl Acad Sci U S A (1995) 0.88
Intramolecular charge transfer in the bacteriorhodopsin mutants Asp85-->Asn and Asp212-->Asn: effects of pH and anions. Biophys J (1995) 0.86
Location of chemically modified lysine 41 in the structure of bacteriorhodopsin by neutron diffraction. Biophys J (1986) 0.86
Chromophore orientation in bacteriorhodopsin determined from the angular dependence of deuterium nuclear magnetic resonance spectra of oriented purple membranes. Biochemistry (1998) 0.86
Time-resolved surface charge change on the cytoplasmic side of bacteriorhodopsin. FEBS Lett (1995) 0.85
Covalent labeling of functional states of the acetylcholine receptor. Effects of antagonists on the receptor conformation. Eur J Biochem (1985) 0.84
Effect of introducing different carboxylate-containing side chains at position 85 on chromophore formation and proton transport in bacteriorhodopsin. J Biol Chem (1992) 0.84
X-ray diffraction of a cysteine-containing bacteriorhodopsin mutant and its mercury derivative. Localization of an amino acid residue in the loop of an integral membrane protein. Biochemistry (1993) 0.84
Kinetics of the light-induced proton translocation associated with the pH-dependent formation of the metarhodopsin I/II equilibrium of bovine rhodopsin. Biochemistry (1998) 0.83
Order and viscosity of membranes: analysis by time-resolved fluorescence depolarization. Methods Enzymol (1989) 0.82
The angles between the C(1)-, C(5)-, and C(9)-methyl bonds of the retinylidene chromophore and the membrane normal increase in the M intermediate of bacteriorhodopsin: direct determination with solid-state (2)H NMR. Biochemistry (1999) 0.81
Circular dichroism and fluorescence studies on the binding of ligands to the alpha subunit of tryptophan synthase. Biochemistry (1975) 0.81
Sulfur distribution in bacteriorhodopsin from multiple wavelength anomalous diffraction near the sulfur K-edge with synchrotron x-ray radiation. Biophys J (1998) 0.81
The self-association of ATP: thermodynamics and geometry. Biophys Chem (1975) 0.80
Bacteriorhodopsin: the effect of bilayer thickness on 2D-array formation, and the structural re-alignment of retinal through the photocycle. Biophys Chem (2006) 0.77
Probing exocytosis by fluorescence and capacitance measurements: a comparison. J Protein Chem (1989) 0.77
Structure of the interhelical loops and carboxyl terminus of bacteriorhodopsin by X-ray diffraction using site-directed heavy-atom labeling. Biochemistry (1998) 0.75
Decreased lipid order induced by microsomal cytochrome P-450 and NADPH-cytochrome P-450 reductase in model membranes: fluorescence and electron spin resonance studies. Biochemistry (1985) 0.75
Circular dichroism for determining secondary structure and state of aggregation of membrane proteins. Methods Enzymol (1989) 0.75