Published in Mol Cell on May 28, 2009
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Proc Natl Acad Sci U S A (2012) 3.42
Heterohexameric ring arrangement of the eukaryotic proteasomal ATPases: implications for proteasome structure and assembly. Mol Cell (2010) 2.35
ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle. Cell (2011) 2.27
Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Proc Natl Acad Sci U S A (2010) 2.05
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Structural insights on the Mycobacterium tuberculosis proteasomal ATPase Mpa. Structure (2009) 1.96
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The mycobacterial Mpa-proteasome unfolds and degrades pupylated substrates by engaging Pup's N-terminus. EMBO J (2010) 1.67
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Assembly, structure, and function of the 26S proteasome. Trends Cell Biol (2010) 1.61
Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions. EMBO J (2009) 1.60
The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together. Proc Natl Acad Sci U S A (2011) 1.57
Regulated protein turnover: snapshots of the proteasome in action. Nat Rev Mol Cell Biol (2014) 1.57
Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11. Proc Natl Acad Sci U S A (2014) 1.57
Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocation. Proc Natl Acad Sci U S A (2013) 1.50
Defining the geometry of the two-component proteasome degron. Nat Chem Biol (2011) 1.45
Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy. Proc Natl Acad Sci U S A (2012) 1.42
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Binding-induced folding of prokaryotic ubiquitin-like protein on the Mycobacterium proteasomal ATPase targets substrates for degradation. Nat Struct Mol Biol (2010) 1.40
Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome. Proc Natl Acad Sci U S A (2014) 1.37
An asymmetric interface between the regulatory and core particles of the proteasome. Nat Struct Mol Biol (2011) 1.36
An atomic model AAA-ATPase/20S core particle sub-complex of the 26S proteasome. Biochem Biophys Res Commun (2009) 1.28
Toward an integrated structural model of the 26S proteasome. Mol Cell Proteomics (2010) 1.19
Structural models for interactions between the 20S proteasome and its PAN/19S activators. J Biol Chem (2009) 1.17
Proteasomes and protein conjugation across domains of life. Nat Rev Microbiol (2011) 1.12
Mapping the structural topology of the yeast 19S proteasomal regulatory particle using chemical cross-linking and probabilistic modeling. Mol Cell Proteomics (2012) 1.10
Gates, Channels, and Switches: Elements of the Proteasome Machine. Trends Biochem Sci (2015) 1.09
Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assembly. Proc Natl Acad Sci U S A (2012) 1.05
Order of the proteasomal ATPases and eukaryotic proteasome assembly. Cell Biochem Biophys (2011) 1.03
Functional asymmetries of proteasome translocase pore. J Biol Chem (2012) 1.01
Local and global mobility in the ClpA AAA+ chaperone detected by cryo-electron microscopy: functional connotations. Structure (2010) 0.97
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Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis. Nat Cell Biol (2015) 0.92
Assembly manual for the proteasome regulatory particle: the first draft. Biochem Soc Trans (2010) 0.91
The pup-proteasome system of Mycobacterium tuberculosis. Subcell Biochem (2013) 0.90
Conformational dynamics of the Rpt6 ATPase in proteasome assembly and Rpn14 binding. Structure (2013) 0.87
Structural insights into proteasome activation by the 19S regulatory particle. Biochemistry (2013) 0.87
Bacterial Proteasomes. Annu Rev Microbiol (2015) 0.85
Time-resolved neutron scattering provides new insight into protein substrate processing by a AAA+ unfoldase. Sci Rep (2017) 0.80
Archaeal proteasomes and sampylation. Subcell Biochem (2013) 0.79
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An archaeal homolog of proteasome assembly factor functions as a proteasome activator. PLoS One (2013) 0.78
Disulfide engineering to map subunit interactions in the proteasome and other macromolecular complexes. Methods Mol Biol (2012) 0.78
Evolution of proteasome regulators in eukaryotes. Genome Biol Evol (2015) 0.78
Structural and biochemical properties of an extreme 'salt-loving' proteasome activating nucleotidase from the archaeon Haloferax volcanii. Extremophiles (2013) 0.78
Prokaryotic proteasomes: nanocompartments of degradation. J Mol Microbiol Biotechnol (2013) 0.78
Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design. Protein Sci (2015) 0.76
Bacterial Proteasomes: Mechanistic and Functional Insights. Microbiol Mol Biol Rev (2016) 0.76
The proteasome's crown for destruction. Mol Cell (2009) 0.75
Design, purification and characterization of a soluble variant of the integral membrane protein MotB for structural studies. J R Soc Interface (2013) 0.75
Reversible phosphorylation of the 26S proteasome. Protein Cell (2017) 0.75
High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx. Cell Res (2017) 0.75
Emerging mechanistic insights into AAA complexes regulating proteasomal degradation. Biomolecules (2014) 0.75
Proteasome Structure and Assembly. J Mol Biol (2017) 0.75
The HHpred interactive server for protein homology detection and structure prediction. Nucleic Acids Res (2005) 21.68
The HAMP domain structure implies helix rotation in transmembrane signaling. Cell (2006) 4.34
ARIA2: automated NOE assignment and data integration in NMR structure calculation. Bioinformatics (2006) 3.70
The MPI Bioinformatics Toolkit for protein sequence analysis. Nucleic Acids Res (2006) 3.45
ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation. Mol Cell (2003) 3.14
ARIA: automated NOE assignment and NMR structure calculation. Bioinformatics (2003) 2.90
Structure of the human voltage-dependent anion channel. Proc Natl Acad Sci U S A (2008) 2.69
Inferential structure determination. Science (2005) 2.57
Structures of the human and Drosophila 80S ribosome. Nature (2013) 2.36
Effects of multiple deletions of murein hydrolases on viability, septum cleavage, and sensitivity to large toxic molecules in Escherichia coli. J Bacteriol (2002) 2.29
PhyloGenie: automated phylome generation and analysis. Nucleic Acids Res (2004) 2.26
AAA proteins. Curr Opin Struct Biol (2002) 2.25
Substrate recognition by the AAA+ chaperone ClpB. Nat Struct Mol Biol (2004) 2.19
AAA+ proteins and substrate recognition, it all depends on their partner in crime. FEBS Lett (2002) 2.10
Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution. Proc Natl Acad Sci U S A (2010) 1.99
Phylogenetic analysis of AAA proteins. J Struct Biol (2004) 1.92
TPRpred: a tool for prediction of TPR-, PPR- and SEL1-like repeats from protein sequences. BMC Bioinformatics (2007) 1.89
Bartonella adhesin a mediates a proangiogenic host cell response. J Exp Med (2004) 1.84
More than the sum of their parts: on the evolution of proteins from peptides. Bioessays (2003) 1.83
HHsenser: exhaustive transitive profile search using HMM-HMM comparison. Nucleic Acids Res (2006) 1.82
Mycobacterium tuberculosis prcBA genes encode a gated proteasome with broad oligopeptide specificity. Mol Microbiol (2006) 1.79
Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome. Proc Natl Acad Sci U S A (2010) 1.68
Molecular details of Bax activation, oligomerization, and membrane insertion. J Biol Chem (2009) 1.60
The CCPN project: an interim report on a data model for the NMR community. Nat Struct Biol (2002) 1.58
prlF and yhaV encode a new toxin-antitoxin system in Escherichia coli. J Mol Biol (2007) 1.57
Classification of AAA+ proteins. J Struct Biol (2006) 1.55
Validity and reliability of the DDS for severity of delirium in the ICU. Neurocrit Care (2005) 1.52
REPPER--repeats and their periodicities in fibrous proteins. Nucleic Acids Res (2005) 1.50
Evolution of the beta-propeller fold. Proteins (2008) 1.48
Modeling AAA+ ring complexes from monomeric structures. J Struct Biol (2006) 1.48
AbrB-like transcription factors assume a swapped hairpin fold that is evolutionarily related to double-psi beta barrels. Structure (2005) 1.45
Homology of SMP domains to the TULIP superfamily of lipid-binding proteins provides a structural basis for lipid exchange between ER and mitochondria. Bioinformatics (2010) 1.44
Comparative analysis of coiled-coil prediction methods. J Struct Biol (2006) 1.43
Structural basis of outer membrane protein biogenesis in bacteria. J Biol Chem (2011) 1.38
Comprehensive analysis of HAMP domains: implications for transmembrane signal transduction. J Mol Biol (2010) 1.35
The mechanisms of HAMP-mediated signaling in transmembrane receptors. Structure (2011) 1.30
Historical review: another 50th anniversary--new periodicities in coiled coils. Trends Biochem Sci (2003) 1.29
A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting. Mol Cell Biol (2007) 1.23
Gene duplication of the eight-stranded beta-barrel OmpX produces a functional pore: a scenario for the evolution of transmembrane beta-barrels. J Mol Biol (2006) 1.22
Correct folding of the beta-barrel of the human membrane protein VDAC requires a lipid bilayer. J Mol Biol (2007) 1.21
Model structure of the prototypical non-fimbrial adhesin YadA of Yersinia enterocolitica. J Struct Biol (2006) 1.20
A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J (2010) 1.18
Structure of the head of the Bartonella adhesin BadA. PLoS Pathog (2008) 1.17
HHomp--prediction and classification of outer membrane proteins. Nucleic Acids Res (2009) 1.16
The 3D structures of VDAC represent a native conformation. Trends Biochem Sci (2010) 1.13
Mechanism of regulation of receptor histidine kinases. Structure (2012) 1.13
VAT, the thermoplasma homolog of mammalian p97/VCP, is an N domain-regulated protein unfoldase. J Biol Chem (2005) 1.13
Kinetics or equilibrium? A commentary on a recent simulation study of semiochemical dose-response curves of insect olfactory sensing. J Chem Ecol (2014) 1.10
Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS. EMBO Rep (2009) 1.10
Mechanism of 2-oxoglutarate signaling by the Synechococcus elongatus PII signal transduction protein. Proc Natl Acad Sci U S A (2010) 1.09
Purification of the YadA membrane anchor for secondary structure analysis and crystallization. Int J Biol Macromol (2006) 1.09
Evolutionary relationships of microbial aromatic prenyltransferases. PLoS One (2011) 1.09
A conserved glycine residue of trimeric autotransporter domains plays a key role in Yersinia adhesin A autotransport. J Bacteriol (2007) 1.08
SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay. Genes Dev (2010) 1.08
Cradle-loop barrels and the concept of metafolds in protein classification by natural descent. Curr Opin Struct Biol (2008) 1.07
The Sulfolobus solfataricus AAA protein Sso0909, a homologue of the eukaryotic ESCRT Vps4 ATPase. Biochem Soc Trans (2008) 1.07
Omp85 from the thermophilic cyanobacterium Thermosynechococcus elongatus differs from proteobacterial Omp85 in structure and domain composition. J Biol Chem (2010) 1.07
Nucleotide-dependent protein folding in the type II chaperonin from the mesophilic archaeon Methanococcus maripaludis. Biochem J (2003) 1.07
A coiled-coil motif that sequesters ions to the hydrophobic core. Proc Natl Acad Sci U S A (2009) 1.07
Common evolutionary origin of swapped-hairpin and double-psi beta barrels. Structure (2006) 1.06
High-level expression, refolding and probing the natural fold of the human voltage-dependent anion channel isoforms I and II. J Membr Biol (2007) 1.06
A galaxy of folds. Protein Sci (2010) 1.05
GNA33 from Neisseria meningitidis serogroup B encodes a membrane-bound lytic transglycosylase (MltA). Eur J Biochem (2002) 1.05
Membrane-protein structure determination by solid-state NMR spectroscopy of microcrystals. Nat Methods (2012) 1.05
Structure of a halophilic nucleoside diphosphate kinase from Halobacterium salinarum. FEBS Lett (2005) 1.02
Mutations in p97/VCP induce unfolding activity. FEBS Lett (2007) 1.02
The head of Bartonella adhesin A is crucial for host cell interaction of Bartonella henselae. Cell Microbiol (2008) 1.01
The N-terminal coiled coil of the Rhodococcus erythropolis ARC AAA ATPase is neither necessary for oligomerization nor nucleotide hydrolysis. J Struct Biol (2004) 1.01
The Tim21 binding domain connects the preprotein translocases of both mitochondrial membranes. EMBO Rep (2006) 1.00
On the origin of the histone fold. BMC Struct Biol (2007) 1.00
Functional mapping of YadA- and Ail-mediated binding of human factor H to Yersinia enterocolitica serotype O:3. Infect Immun (2008) 0.99
Coiled coils meet the chaperone world. Trends Biochem Sci (2004) 0.98
A new expression system for protein crystallization using trimeric coiled-coil adaptors. Protein Eng Des Sel (2007) 0.98
Comparative analysis of structural and dynamic properties of the loaded and unloaded hemophore HasA: functional implications. J Mol Biol (2007) 0.98
Correction of spin diffusion during iterative automated NOE assignment. J Magn Reson (2004) 0.98
A lung area estimation method for analysis of ventilation inhomogeneity based on electrical impedance tomography. J Xray Sci Technol (2010) 0.96
Modeling errors in NOE data with a log-normal distribution improves the quality of NMR structures. J Am Chem Soc (2005) 0.96
ISD: a software package for Bayesian NMR structure calculation. Bioinformatics (2008) 0.95
The structure of E. coli IgG-binding protein D suggests a general model for bending and binding in trimeric autotransporter adhesins. Structure (2011) 0.95
Influence of different assignment conditions on the determination of symmetric homodimeric structures with ARIA. Proteins (2009) 0.95
Complete fiber structures of complex trimeric autotransporter adhesins conserved in enterobacteria. Proc Natl Acad Sci U S A (2012) 0.95
Conformational changes and protein stability of the pro-apoptotic protein Bax. J Bioenerg Biomembr (2009) 0.95
HHfrag: HMM-based fragment detection using HHpred. Bioinformatics (2011) 0.95