Published in Structure on March 09, 2011
HAMP domain conformers that propagate opposite signals in bacterial chemoreceptors. PLoS Biol (2013) 1.60
HAMP domain structural determinants for signalling and sensory adaptation in Tsr, the Escherichia coli serine chemoreceptor. Mol Microbiol (2013) 1.57
Mechanistic insights revealed by the crystal structure of a histidine kinase with signal transducer and sensor domains. PLoS Biol (2013) 1.35
RND-type efflux pumps in multidrug-resistant clinical isolates of Acinetobacter baumannii: major role for AdeABC overexpression and AdeRS mutations. Antimicrob Agents Chemother (2013) 1.20
The MPI bioinformatics Toolkit as an integrative platform for advanced protein sequence and structure analysis. Nucleic Acids Res (2016) 1.10
Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update. Trends Microbiol (2015) 1.10
Segmental helical motions and dynamical asymmetry modulate histidine kinase autophosphorylation. PLoS Biol (2014) 1.07
Determinants of homodimerization specificity in histidine kinases. J Mol Biol (2011) 1.01
Stress-induced remodeling of the bacterial proteome. Curr Biol (2014) 0.98
Functional and structural comparison of pyrrolnitrin- and iprodione-induced modifications in the class III histidine-kinase Bos1 of Botrytis cinerea. PLoS One (2012) 0.97
Signal transduction in histidine kinases: insights from new structures. Structure (2015) 0.95
HAMP domain-mediated signal transduction probed with a mycobacterial adenylyl cyclase as a reporter. J Biol Chem (2011) 0.92
Mechanistic insight into the conserved allosteric regulation of periplasmic proteolysis by the signaling molecule cyclic-di-GMP. Elife (2014) 0.91
Functional suppression of HAMP domain signaling defects in the E. coli serine chemoreceptor. J Mol Biol (2014) 0.91
Molecular Mechanisms of Two-Component Signal Transduction. J Mol Biol (2016) 0.87
Different conformations of the kinase-on and kinase-off signaling states in the Aer HAMP domain. J Bacteriol (2011) 0.86
The S-helix determines the signal in a Tsr receptor/adenylyl cyclase reporter. J Biol Chem (2012) 0.85
Extracellular heme uptake and the challenges of bacterial cell membranes. Curr Top Membr (2012) 0.83
Bacterial chemoreceptor dynamics correlate with activity state and are coupled over long distances. Proc Natl Acad Sci U S A (2015) 0.83
Two distinct states of the HAMP domain from sensory rhodopsin transducer observed in unbiased molecular dynamics simulations. PLoS One (2013) 0.82
HAMP Domain Rotation and Tilting Movements Associated with Signal Transduction in the PhoQ Sensor Kinase. MBio (2015) 0.79
The HAMP signal relay domain adopts multiple conformational states through collective piston and tilt motions. PLoS Comput Biol (2013) 0.79
Delineating PAS-HAMP interaction surfaces and signalling-associated changes in the aerotaxis receptor Aer. Mol Microbiol (2016) 0.78
Structural characterization of AS1-membrane interactions from a subset of HAMP domains. Biochim Biophys Acta (2011) 0.78
Differential repositioning of the second transmembrane helices from E. coli Tar and EnvZ upon moving the flanking aromatic residues. Biochim Biophys Acta (2014) 0.77
Differential role of HAMP-like linkers in regulating the functionality of the group III histidine kinase DhNik1p. J Biol Chem (2014) 0.77
Coiled-coil destabilizing residues in the group A Streptococcus M1 protein are required for functional interaction. Proc Natl Acad Sci U S A (2016) 0.76
Evidence for a Helix-Clutch Mechanism of Transmembrane Signaling in a Bacterial Chemoreceptor. J Mol Biol (2016) 0.76
The accommodation index measures the perturbation associated with insertions and deletions in coiled-coils. Application to understand signaling in histidine kinases. Protein Sci (2016) 0.75
Employing aromatic tuning to modulate output from two-component signaling circuits. J Biol Eng (2015) 0.75
Methylatable Signaling Helix Coordinated Inhibitory Receiver Domain in Sensor Kinase Modulates Environmental Stress Response in Bacillus Cereus. PLoS One (2015) 0.75
Mutational analysis of dimeric linkers in peri- and cytoplasmic domains of histidine kinase DctB reveals their functional roles in signal transduction. Open Biol (2014) 0.75
Stability and Conformation of a Chemoreceptor HAMP Domain Chimera Correlates with Signaling Properties. Biophys J (2017) 0.75
Coincidence detection and bi-directional transmembrane signaling control a bacterial second messenger receptor. Elife (2016) 0.75
New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex. Sci Rep (2017) 0.75
The HHpred interactive server for protein homology detection and structure prediction. Nucleic Acids Res (2005) 21.68
MODOMICS: a database of RNA modification pathways--2013 update. Nucleic Acids Res (2012) 4.43
The HAMP domain structure implies helix rotation in transmembrane signaling. Cell (2006) 4.34
The MPI Bioinformatics Toolkit for protein sequence analysis. Nucleic Acids Res (2006) 3.45
MODOMICS: a database of RNA modification pathways. 2008 update. Nucleic Acids Res (2008) 2.84
Structure of the human voltage-dependent anion channel. Proc Natl Acad Sci U S A (2008) 2.69
PhyloGenie: automated phylome generation and analysis. Nucleic Acids Res (2004) 2.26
Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium. Eur J Immunol (2008) 2.25
AAA proteins. Curr Opin Struct Biol (2002) 2.25
Substrate recognition by the AAA+ chaperone ClpB. Nat Struct Mol Biol (2004) 2.19
AAA+ proteins and substrate recognition, it all depends on their partner in crime. FEBS Lett (2002) 2.10
Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPases. Mol Cell (2009) 2.05
Point mutations in the aromatic/arginine region in aquaporin 1 allow passage of urea, glycerol, ammonia, and protons. Proc Natl Acad Sci U S A (2006) 2.02
Ton-dependent colicins and microcins: modular design and evolution. Biochimie (2002) 1.95
Phylogenetic analysis of AAA proteins. J Struct Biol (2004) 1.92
TPRpred: a tool for prediction of TPR-, PPR- and SEL1-like repeats from protein sequences. BMC Bioinformatics (2007) 1.89
Bartonella adhesin a mediates a proangiogenic host cell response. J Exp Med (2004) 1.84
More than the sum of their parts: on the evolution of proteins from peptides. Bioessays (2003) 1.83
A single, bi-functional aquaglyceroporin in blood-stage Plasmodium falciparum malaria parasites. J Biol Chem (2001) 1.83
HHsenser: exhaustive transitive profile search using HMM-HMM comparison. Nucleic Acids Res (2006) 1.82
The class III adenylyl cyclases: multi-purpose signalling modules. Cell Signal (2003) 1.75
Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases. BMC Bioinformatics (2007) 1.74
A conserved spider silk domain acts as a molecular switch that controls fibre assembly. Nature (2010) 1.65
Molecular details of Bax activation, oligomerization, and membrane insertion. J Biol Chem (2009) 1.60
The structure of salmochelins: C-glucosylated enterobactins of Salmonella enterica. Biometals (2004) 1.60
prlF and yhaV encode a new toxin-antitoxin system in Escherichia coli. J Mol Biol (2007) 1.57
Classification of AAA+ proteins. J Struct Biol (2006) 1.55
Validity and reliability of the DDS for severity of delirium in the ICU. Neurocrit Care (2005) 1.52
The structure of a pH-sensing mycobacterial adenylyl cyclase holoenzyme. Science (2005) 1.52
Recent insights into iron import by bacteria. Curr Opin Chem Biol (2011) 1.51
REPPER--repeats and their periodicities in fibrous proteins. Nucleic Acids Res (2005) 1.50
Evolution of the beta-propeller fold. Proteins (2008) 1.48
Modeling AAA+ ring complexes from monomeric structures. J Struct Biol (2006) 1.48
AbrB-like transcription factors assume a swapped hairpin fold that is evolutionarily related to double-psi beta barrels. Structure (2005) 1.45
Homology of SMP domains to the TULIP superfamily of lipid-binding proteins provides a structural basis for lipid exchange between ER and mitochondria. Bioinformatics (2010) 1.44
Comparative analysis of coiled-coil prediction methods. J Struct Biol (2006) 1.43
Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2. Blood (2009) 1.40
Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: modes of ligand binding and dimerization. Proc Natl Acad Sci U S A (2005) 1.40
Structural basis of outer membrane protein biogenesis in bacteria. J Biol Chem (2011) 1.38
Comprehensive analysis of HAMP domains: implications for transmembrane signal transduction. J Mol Biol (2010) 1.35
Molecular dissection of water and glycerol permeability of the aquaglyceroporin from Plasmodium falciparum by mutational analysis. Proc Natl Acad Sci U S A (2004) 1.34
Hypoxia-independent activation of HIF-1 by enterobacteriaceae and their siderophores. Gastroenterology (2007) 1.29
Historical review: another 50th anniversary--new periodicities in coiled coils. Trends Biochem Sci (2003) 1.29
A GAF-domain-regulated adenylyl cyclase from Anabaena is a self-activating cAMP switch. EMBO J (2002) 1.28
The cytosolic domains of Ca2+-sensitive adenylyl cyclases dictate their targeting to plasma membrane lipid rafts. J Biol Chem (2004) 1.25
Origin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900c. EMBO J (2005) 1.23
A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting. Mol Cell Biol (2007) 1.23
Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes. Mol Cell Biol (2008) 1.22
Gene duplication of the eight-stranded beta-barrel OmpX produces a functional pore: a scenario for the evolution of transmembrane beta-barrels. J Mol Biol (2006) 1.22
Correct folding of the beta-barrel of the human membrane protein VDAC requires a lipid bilayer. J Mol Biol (2007) 1.21
Model structure of the prototypical non-fimbrial adhesin YadA of Yersinia enterocolitica. J Struct Biol (2006) 1.20
Functions of the siderophore esterases IroD and IroE in iron-salmochelin utilization. Microbiology (2005) 1.20
A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J (2010) 1.18
Environmental factors influence the production of enterobactin, salmochelin, aerobactin, and yersiniabactin in Escherichia coli strain Nissle 1917. Int J Med Microbiol (2006) 1.17
Structure of the head of the Bartonella adhesin BadA. PLoS Pathog (2008) 1.17
HHomp--prediction and classification of outer membrane proteins. Nucleic Acids Res (2009) 1.16
A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation. Nat Struct Mol Biol (2012) 1.13
The 3D structures of VDAC represent a native conformation. Trends Biochem Sci (2010) 1.13
Mechanism of regulation of receptor histidine kinases. Structure (2012) 1.13
Ammonia permeability of the aquaglyceroporins from Plasmodium falciparum, Toxoplasma gondii and Trypansoma brucei. Mol Microbiol (2006) 1.13
Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS. EMBO Rep (2009) 1.10
Mechanism of 2-oxoglutarate signaling by the Synechococcus elongatus PII signal transduction protein. Proc Natl Acad Sci U S A (2010) 1.09
Purification of the YadA membrane anchor for secondary structure analysis and crystallization. Int J Biol Macromol (2006) 1.09
Evolutionary relationships of microbial aromatic prenyltransferases. PLoS One (2011) 1.09
Trimeric structure and flexibility of the L1ORF1 protein in human L1 retrotransposition. Nat Struct Mol Biol (2011) 1.08
SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay. Genes Dev (2010) 1.08
A conserved glycine residue of trimeric autotransporter domains plays a key role in Yersinia adhesin A autotransport. J Bacteriol (2007) 1.08
Cradle-loop barrels and the concept of metafolds in protein classification by natural descent. Curr Opin Struct Biol (2008) 1.07
The Sulfolobus solfataricus AAA protein Sso0909, a homologue of the eukaryotic ESCRT Vps4 ATPase. Biochem Soc Trans (2008) 1.07
A coiled-coil motif that sequesters ions to the hydrophobic core. Proc Natl Acad Sci U S A (2009) 1.07
Nucleotide-dependent protein folding in the type II chaperonin from the mesophilic archaeon Methanococcus maripaludis. Biochem J (2003) 1.07
Omp85 from the thermophilic cyanobacterium Thermosynechococcus elongatus differs from proteobacterial Omp85 in structure and domain composition. J Biol Chem (2010) 1.07
Salmochelin, the long-overlooked catecholate siderophore of Salmonella. Biometals (2009) 1.06
Common evolutionary origin of swapped-hairpin and double-psi beta barrels. Structure (2006) 1.06
High-level expression, refolding and probing the natural fold of the human voltage-dependent anion channel isoforms I and II. J Membr Biol (2007) 1.06
A galaxy of folds. Protein Sci (2010) 1.05
Adenylyl cyclase Rv1264 from Mycobacterium tuberculosis has an autoinhibitory N-terminal domain. J Biol Chem (2002) 1.05