Published in Nat Med on June 01, 2009
Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels. Dev Cell (2010) 4.99
Renal fibrosis: novel insights into mechanisms and therapeutic targets. Nat Rev Nephrol (2010) 2.55
Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions. Angiogenesis (2014) 2.07
Animal models of choroidal and retinal neovascularization. Prog Retin Eye Res (2010) 1.79
Extracellular matrix, inflammation, and the angiogenic response. Cardiovasc Res (2010) 1.45
Vascular endothelial growth factor and substrate mechanics regulate in vitro tubulogenesis of endothelial progenitor cells. J Cell Mol Med (2010) 1.24
Mechanical regulation of vascular growth and tissue regeneration in vivo. Proc Natl Acad Sci U S A (2011) 1.16
Cellular and molecular aspects of vascular dysfunction in systemic sclerosis. Nat Rev Rheumatol (2010) 1.08
Transforming Growth Factor-β and Endoglin Signaling Orchestrate Wound Healing. Front Physiol (2011) 1.07
The aortic ring model of angiogenesis: a quarter century of search and discovery. J Cell Mol Med (2009) 1.07
Angiogenesis in wounds treated by microdeformational wound therapy. Ann Surg (2011) 1.05
Microvascular remodeling and wound healing: a role for pericytes. Int J Biochem Cell Biol (2012) 1.01
Tissue deformation spatially modulates VEGF signaling and angiogenesis. Proc Natl Acad Sci U S A (2012) 1.01
Integrin signaling and lung cancer. Cell Adh Migr (2010) 0.99
Intravital immunofluorescence for visualizing the microcirculatory and immune microenvironments in the mouse ear dermis. PLoS One (2013) 0.98
Effects of Low-dose Morphine on Nitric Oxide Concentration and Angiogenesis in Two-kidney One Clip Hypertensive Rats. Iran J Basic Med Sci (2011) 0.98
Microvascular rarefaction: the decline and fall of blood vessels. Organogenesis (2010) 0.96
Markedly decreased blood perfusion of pancreatic islets transplanted intraportally into the liver: disruption of islet integrity necessary for islet revascularization. Diabetes (2012) 0.95
The chicken chorioallantoic membrane model in biology, medicine and bioengineering. Angiogenesis (2014) 0.94
Pericytes: multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle. Front Aging Neurosci (2014) 0.93
Engineering the Lymphatic System. Cardiovasc Eng Technol (2011) 0.89
An in vivo neovascularization assay for screening regulators of angiogenesis and assessing their effects on pre-existing vessels. Angiogenesis (2012) 0.87
Skeletal muscle tissue engineering: strategies for volumetric constructs. Front Physiol (2014) 0.86
Growth and regression of vasculature in healthy and diabetic mice after hindlimb ischemia. Am J Physiol Regul Integr Comp Physiol (2012) 0.86
MFG-E8 regulates angiogenesis in cutaneous wound healing. Am J Pathol (2014) 0.84
Optimization and regeneration kinetics of lymphatic-specific photodynamic therapy in the mouse dermis. Angiogenesis (2013) 0.84
Selective blockade of cytoskeletal actin remodeling reduces experimental choroidal neovascularization. Invest Ophthalmol Vis Sci (2011) 0.83
Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases. J Cell Mol Med (2011) 0.82
A morphometric study of mechanotransductively induced dermal neovascularization. Plast Reconstr Surg (2011) 0.81
EMP2 regulates angiogenesis in endometrial cancer cells through induction of VEGF. Oncogene (2013) 0.81
[Non-antagonistic influence of Krumeich's intrastromal corneal ring in an experimental tissue culture system]. Ophthalmologe (2016) 0.78
Aqueous outflow - A continuum from trabecular meshwork to episcleral veins. Prog Retin Eye Res (2016) 0.78
Tension in the vasculature. Nat Med (2009) 0.77
Structurally governed cell mechanotransduction through multiscale modeling. Sci Rep (2015) 0.77
Gene signatures in wound tissue as evidenced by molecular profiling in the chick embryo model. BMC Genomics (2010) 0.77
Negative pressure therapy stimulates healing of critical-size calvarial defects in rabbits. Bonekey Rep (2013) 0.77
Three types of dermal grafts in rats: the importance of mechanical property and structural design. Biomed Eng Online (2013) 0.77
Cutaneous Imaging Technologies in Acute Burn and Chronic Wound Care. Plast Reconstr Surg (2016) 0.76
Strain tunes proteolytic degradation and diffusive transport in fibrin networks. Biomacromolecules (2012) 0.76
Static mechanical strain induces capillary endothelial cell cycle re-entry and sprouting. Phys Biol (2016) 0.76
Magnetically actuated tissue engineered scaffold: insights into mechanism of physical stimulation. Nanoscale (2016) 0.76
Mechanical strain controls endothelial patterning during angiogenic sprouting. Cell Mol Bioeng (2012) 0.76
Long-term intravital immunofluorescence imaging of tissue matrix components with epifluorescence and two-photon microscopy. J Vis Exp (2014) 0.76
Anti-angiogenic Therapy in Cancer: Downsides and New Pivots for Precision Medicine. Front Pharmacol (2017) 0.75
Negative pressure wound therapy promotes vessel destabilization and maturation at various stages of wound healing and thus influences wound prognosis. Exp Ther Med (2016) 0.75
Genome-wide expression differences in anti-Vegf and dexamethasone treatment of inflammatory angiogenesis in the rat cornea. Sci Rep (2017) 0.75
Cancer-associated fibroblasts support vascular growth through mechanical force. Sci Rep (2017) 0.75
Cutaneous wound healing. N Engl J Med (1999) 19.12
Fibroblasts in cancer. Nat Rev Cancer (2006) 18.95
Mechanisms of angiogenesis. Nature (1997) 18.04
Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med (1986) 17.64
Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol (2002) 14.80
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol (2003) 12.96
The myofibroblast in wound healing and fibrocontractive diseases. J Pathol (2003) 6.16
Stem-cell therapy for cardiac disease. Nature (2008) 5.75
Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors. Cancer Res (2004) 5.65
Granulation tissue as a contractile organ. A study of structure and function. J Exp Med (1972) 5.42
Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis. Microvasc Res (1977) 5.19
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature (2008) 5.15
Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Experientia (1971) 5.14
The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1. J Cell Biol (1998) 3.65
A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature (2009) 3.44
Angiogenesis in wound healing. J Investig Dermatol Symp Proc (2000) 3.12
Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology. Circ Res (2002) 2.96
Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor. Lab Invest (2000) 2.92
Tensional forces in fibrillar extracellular matrices control directional capillary sprouting. J Cell Sci (1999) 2.71
Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair. Am J Pathol (2003) 2.22
Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis. Circ Res (2003) 2.12
Mechanisms of neovascularization. Vascular sprouting can occur without proliferation of endothelial cells. Lab Invest (1984) 1.99
Rous-Whipple Award Lecture. How tumors make bad blood vessels and stroma. Am J Pathol (2003) 1.95
Effect of precise mechanical loading on fibroblast populated collagen lattices: morphological changes. Cell Motil Cytoskeleton (1998) 1.88
The mechanism of action of the vacuum-assisted closure device. Plast Reconstr Surg (2008) 1.68
Vascular remodeling by intussusceptive angiogenesis. Cell Tissue Res (2003) 1.49
Vascular morphogenesis and remodeling in a model of tissue repair: blood vessel formation and growth in the ovarian pedicle after ovariectomy. Circ Res (2001) 1.37
Angiogenesis in the mouse cornea. Science (1979) 1.36
Determinants of endothelial cell phenotype in venules. Microcirculation (2000) 1.21
The effects of cross-linking of collagen-glycosaminoglycan scaffolds on compressive stiffness, chondrocyte-mediated contraction, proliferation and biosynthesis. Biomaterials (2001) 1.19
Inactivation of Src family kinases inhibits angiogenesis in vivo: implications for a mechanism involving organization of the actin cytoskeleton. Exp Cell Res (2003) 1.08
Mesenchymal cell activation is the rate-limiting step of granulation tissue induction. Am J Pathol (1996) 1.06
Intussusceptive angiogenesis--the alternative to capillary sprouting. Mol Aspects Med (2002) 1.06
Making vascular networks in the adult: branching morphogenesis without a roadmap. Trends Cell Biol (2003) 1.05
Antiangiogenic tumour therapy: will it work? Trends Pharmacol Sci (1998) 1.04
Tumor recovery by angiogenic switch from sprouting to intussusceptive angiogenesis after treatment with PTK787/ZK222584 or ionizing radiation. Am J Pathol (2008) 1.03
Microcirculatory flow changes during tissue growth. Microvasc Res (1983) 0.96
Limbal microvasculature of the rat eye. Invest Ophthalmol Vis Sci (1995) 0.96
Delayed inflammation-associated corneal neovascularization in MMP-2-deficient mice. Exp Eye Res (2005) 0.95
Normal scarring: importance of myofibroblasts. Wound Repair Regen (2002) 0.95
Collagen telopeptides (cross-linking sites) play a role in collagen gel lattice contraction. J Invest Dermatol (1991) 0.93
A clinical model of dermal wound angiogenesis. Wound Repair Regen (2003) 0.88
An ex vivo model for functional studies of myofibroblasts. Lab Invest (2005) 0.86
Endometrial angiogenesis. Angiogenesis (1998) 0.85
The microvascular composition of the healing wound compared at skin sites with nutritive versus arteriovenous perfusion. J Surg Res (1998) 0.82
Histology and ultrastructure of the chorioallantoic membrane of the mallard duck (Anas platyrhynchos). Anat Rec (2000) 0.82
Microcirculation is similar in ischemic and venous ulcers. Microvasc Res (2001) 0.81
The limbal vascular response to corneal injury. An autoradiographic study. Cornea (1989) 0.80
Benefit from bevacizumab for macular edema in central retinal vein occlusion: twelve-month results of a prospective, randomized study. Ophthalmology (2012) 1.78
Angiomotin regulates endothelial cell migration during embryonic angiogenesis. Genes Dev (2007) 1.49
p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2-stimulated angiogenesis. J Cell Biol (2002) 1.38
Bevacizumab for macular edema in central retinal vein occlusion: a prospective, randomized, double-masked clinical study. Ophthalmology (2012) 1.15
Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1. Genome Med (2009) 1.15
Reduced choroidal neovascular membrane formation in matrix metalloproteinase-2-deficient mice. Invest Ophthalmol Vis Sci (2003) 1.14
Inactivation of Src family kinases inhibits angiogenesis in vivo: implications for a mechanism involving organization of the actin cytoskeleton. Exp Cell Res (2003) 1.08
Role of the amino-terminal domains of MEKKs in the activation of NF kappa B and MAPK pathways and in the regulation of cell proliferation and apoptosis. Cell Signal (2002) 1.05
Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor. Invest Ophthalmol Vis Sci (2008) 0.99
Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer. Exp Cell Res (2007) 0.98
A prospective study on intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration of different durations. Acta Ophthalmol (2007) 0.96
Delayed inflammation-associated corneal neovascularization in MMP-2-deficient mice. Exp Eye Res (2005) 0.95
Therapeutic antibodies targeting angiomotin inhibit angiogenesis in vivo. FASEB J (2007) 0.90
Structure and function of the N-cadherin/catenin complex in retinoblastoma. Invest Ophthalmol Vis Sci (2002) 0.89
Subthreshold transpupillary thermotherapy reduces experimental choroidal neovascularization in the mouse without collateral damage to the neural retina. Invest Ophthalmol Vis Sci (2004) 0.88
An in vivo neovascularization assay for screening regulators of angiogenesis and assessing their effects on pre-existing vessels. Angiogenesis (2012) 0.87
Role of aggregated medin in the pathogenesis of thoracic aortic aneurysm and dissection. Lab Invest (2007) 0.86
An ex vivo model for functional studies of myofibroblasts. Lab Invest (2005) 0.86
Lactadherin binds to elastin--a starting point for medin amyloid formation? Amyloid (2006) 0.85
How to make tetracycline-regulated transgene expression go on and off. Anal Biochem (2002) 0.84
Photodynamic therapy of experimental choroidal neovascularization in the mouse. Curr Eye Res (2006) 0.84
A new mechanism of blood vessel growth - hope for new treatment strategies. Discov Med (2009) 0.83
MicroRNA-24 suppression of N-deacetylase/N-sulfotransferase-1 (NDST1) reduces endothelial cell responsiveness to vascular endothelial growth factor A (VEGFA). J Biol Chem (2013) 0.81
Regulation of endothelial cell differentiation and transformation by H-Ras. Exp Cell Res (2003) 0.80
In Vivo Imaging of Subretinal Bleb-Induced Outer Retinal Degeneration in the Rabbit. Invest Ophthalmol Vis Sci (2015) 0.80
Combination therapy with low-dose transpupillary thermotherapy and intravitreal ranibizumab for neovascular age-related macular degeneration: a 24-month prospective randomised clinical study. Br J Ophthalmol (2012) 0.79
The novel alkylating prodrug melflufen (J1) inhibits angiogenesis in vitro and in vivo. Biochem Pharmacol (2013) 0.79
Vision-related function after low-dose transpupillary thermotherapy versus photodynamic therapy for neovascular age-related macular degeneration. Acta Ophthalmol (2010) 0.79
Retinal vascular development and pathologic retinal angiogenesis are not impaired in matrix metalloproteinase-2 deficient mice. Curr Eye Res (2005) 0.79
Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor. Acta Ophthalmol (2008) 0.78
TIMP-3 mRNA is not overexpressed in Sorsby fundus dystrophy. Am J Ophthalmol (2003) 0.78
Visual improvement in central retinal vein occlusion (CRVO) following intravitreal injections of bevacizumab (Avastin(®) ). Acta Ophthalmol (2010) 0.78
Delayed neovascularization in inflammation-induced corneal neovascularization in interleukin-10-deficient mice. Acta Ophthalmol (2008) 0.78
Neovascular age-related macular degeneration: too many theories, too little knowledge? Acta Ophthalmol (2008) 0.77
Involvement of purinergic P2 receptors in experimental retinal neovascularization. Curr Eye Res (2008) 0.77
Intravitreal bevacizumab in central retinal vein occlusion: 18-month results of a prospective clinical trial. Eur J Ophthalmol (2011) 0.77
Optical Coherence Tomography Angiography in Central Retinal Vein Occlusion: Correlation Between the Foveal Avascular Zone and Visual Acuity. Invest Ophthalmol Vis Sci (2016) 0.75
New treatments for neovascular age-related macular degeneration: when should we use them? Acta Ophthalmol Scand (2007) 0.75
Shall we use Avastin or Lucentis for ocular neovascularization? Acta Ophthalmol (2008) 0.75
Donor Endothelial Cell Count Does Not Correlate With Descemet Stripping Automated Endothelial Keratoplasty Transplant Survival After 2 Years of Follow-up. Cornea (2017) 0.75
Seasonality and incidence of central retinal vein occlusion in Sweden: a 6-year study. Ophthalmic Epidemiol (2015) 0.75
Preoperative sub-Tenon's capsule injection of ropivacaine in conjunction with general anesthesia in retinal detachment surgery. Ophthalmology (2007) 0.75
Validation of Catquest-9SF-A Visual Disability Instrument to Evaluate Patient Function After Corneal Transplantation. Cornea (2017) 0.75