Published in Invest Ophthalmol Vis Sci on January 01, 2003
MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix. J Cell Biol (2004) 2.45
Control of matrix metalloproteinase catalytic activity. Matrix Biol (2007) 2.18
Animal models of choroidal and retinal neovascularization. Prog Retin Eye Res (2010) 1.79
Angiomotin regulates endothelial cell migration during embryonic angiogenesis. Genes Dev (2007) 1.49
MMP-2 alters VEGF expression via alphaVbeta3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells. Int J Cancer (2010) 1.48
Animal models of age related macular degeneration. Mol Aspects Med (2012) 1.39
Mediators of ocular angiogenesis. J Genet (2009) 1.17
Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration. Eye (Lond) (2011) 1.04
VEGF receptor blockade markedly reduces retinal microglia/macrophage infiltration into laser-induced CNV. PLoS One (2013) 1.01
Doxycycline-mediated inhibition of choroidal neovascularization. Invest Ophthalmol Vis Sci (2009) 0.95
Pharmacologic and genetic manipulation of MMP-2 and -9 affects retinal neovascularization in rodent models of OIR. Invest Ophthalmol Vis Sci (2007) 0.95
Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy. Mol Vis (2009) 0.92
MMP-2 suppression abrogates irradiation-induced microtubule formation in endothelial cells by inhibiting αvβ3-mediated SDF-1/CXCR4 signaling. Int J Oncol (2013) 0.89
Matrix metalloproteinases in human choroidal neovascular membranes excised following verteporfin photodynamic therapy. Br J Ophthalmol (2007) 0.89
Preventive versus treatment effect of AG3340, a potent matrix metalloproteinase inhibitor in a rat model of choroidal neovascularization. J Ocul Pharmacol Ther (2004) 0.87
Roles of NFκB-miR-29s-MMP-2 circuitry in experimental choroidal neovascularization. J Neuroinflammation (2014) 0.83
Selection of peptide inhibitor to matrix metalloproteinase-2 using phage display and its effects on pancreatic cancer cell lines PANC-1 and CFPAC-1. Int J Biol Sci (2012) 0.83
Modulation of choroidal neovascularization by subretinal injection of retinal pigment epithelium and polystyrene microbeads. Mol Vis (2009) 0.79
Rybp, a polycomb complex-associated protein, is required for mouse eye development. BMC Dev Biol (2007) 0.79
Nuclear factor kappa-B signaling is integral to ocular neovascularization in ischemia-independent microenvironment. PLoS One (2014) 0.78
Phosphatidylserine (PS) Is Exposed in Choroidal Neovascular Endothelium: PS-Targeting Antibodies Inhibit Choroidal Angiogenesis In Vivo and Ex Vivo. Invest Ophthalmol Vis Sci (2015) 0.77
The small tellurium-based compound SAS suppresses inflammation in human retinal pigment epithelium. Mol Vis (2016) 0.75
MMP-2 Rs24386 (C-->T) gene polymorphism and the phenotype of age-related macular degeneration. Int J Ophthalmol (2017) 0.75
Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain. Nat Neurosci (2008) 6.13
Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell (2002) 5.69
Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation. J Neurosci (2007) 4.34
Innate versus learned odour processing in the mouse olfactory bulb. Nature (2007) 4.19
The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Nat Neurosci (2006) 2.87
Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis. J Cell Biol (2003) 2.68
Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. Science (2006) 2.49
Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients. J Clin Invest (2007) 2.45
Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons. Nat Neurosci (2002) 2.25
Uveal melanoma: epidemiologic aspects. Ophthalmol Clin North Am (2005) 2.24
Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa. Dev Cell (2005) 2.21
Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice. Cancer Cell (2003) 2.11
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. Neuron (2005) 2.11
Choroidal biopsies for intraocular tumors of indeterminate origin. Am J Ophthalmol (2005) 1.87
Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice. J Clin Invest (2008) 1.86
Photochemical damage of the retina. Surv Ophthalmol (2006) 1.83
Rac-GAP alpha-chimerin regulates motor-circuit formation as a key mediator of EphrinB3/EphA4 forward signaling. Cell (2007) 1.82
Optogenetic dissection reveals multiple rhythmogenic modules underlying locomotion. Proc Natl Acad Sci U S A (2013) 1.82
Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation. Circulation (2004) 1.80
Benefit from bevacizumab for macular edema in central retinal vein occlusion: twelve-month results of a prospective, randomized study. Ophthalmology (2012) 1.78
Clinical and pathologic characteristics of biopsy-proven iris melanoma: a multicenter international study. Arch Ophthalmol (2011) 1.78
Targeted disruption of the Epm2a gene causes formation of Lafora inclusion bodies, neurodegeneration, ataxia, myoclonus epilepsy and impaired behavioral response in mice. Hum Mol Genet (2002) 1.73
The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis. J Immunol (2002) 1.71
Granuphilin molecularly docks insulin granules to the fusion machinery. J Cell Biol (2005) 1.66
Germinal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation. Mol Cell Biol (2007) 1.63
Ligneous conjunctivitis. Surv Ophthalmol (2003) 1.59
Axonal netrin-Gs transneuronally determine lamina-specific subdendritic segments. Proc Natl Acad Sci U S A (2007) 1.58
Biomechanical regulation of blood vessel growth during tissue vascularization. Nat Med (2009) 1.58
High-efficiency CAG-FLPe deleter mice in C57BL/6J background. Exp Anim (2006) 1.53
A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism. J Biol Chem (2006) 1.52
Angiomotin regulates endothelial cell migration during embryonic angiogenesis. Genes Dev (2007) 1.49
Age-related maculopathy and the impact of blue light hazard. Acta Ophthalmol Scand (2006) 1.47
GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states. J Neurosci (2007) 1.41
Extracellular signal-regulated kinase 2 (ERK2) knockdown mice show deficits in long-term memory; ERK2 has a specific function in learning and memory. J Neurosci (2007) 1.41
Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Development (2007) 1.40
Activation of NMDA receptors promotes dendritic spine development through MMP-mediated ICAM-5 cleavage. J Cell Biol (2007) 1.38
Dorsal telencephalon-specific expression of Cre recombinase in PAC transgenic mice. Genesis (2004) 1.37
Deficiency of gelatinase a suppresses smooth muscle cell invasion and development of experimental intimal hyperplasia. Circulation (2003) 1.35
Complementary expression and neurite outgrowth activity of netrin-G subfamily members. Mech Dev (2002) 1.35
Effect of MMP-2 deficiency on atherosclerotic lesion formation in apoE-deficient mice. Arterioscler Thromb Vasc Biol (2006) 1.35
Calpain mediates excitotoxic DNA fragmentation via mitochondrial pathways in adult brains: evidence from calpastatin mutant mice. J Biol Chem (2005) 1.34
Impaired cerebellar development and function in mice lacking CAPS2, a protein involved in neurotrophin release. J Neurosci (2007) 1.33
Insulin-like growth factor-1 receptor in uveal melanoma: a predictor for metastatic disease and a potential therapeutic target. Invest Ophthalmol Vis Sci (2002) 1.33
Ruthenium brachytherapy for uveal melanoma, 1979-2003: survival and functional outcomes in the Swedish population. Ophthalmology (2005) 1.32
Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome. Hum Mol Genet (2013) 1.32
Glial protein S100B modulates long-term neuronal synaptic plasticity. Proc Natl Acad Sci U S A (2002) 1.27
Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality. J Biol Chem (2003) 1.26
NMDA receptor-dependent pattern transfer from afferents to postsynaptic cells and dendritic differentiation in the barrel cortex. Mol Cell Neurosci (2002) 1.26
Matrix metalloproteinase-2 plays a critical role in the pathogenesis of white matter lesions after chronic cerebral hypoperfusion in rodents. Stroke (2006) 1.26
Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors. J Biol Chem (2005) 1.25
Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane. Mol Biol Cell (2007) 1.24
Loss of M5 muscarinic acetylcholine receptors leads to cerebrovascular and neuronal abnormalities and cognitive deficits in mice. Neurobiol Dis (2006) 1.23
Exuberant thalamocortical axon arborization in cortex-specific NMDAR1 knockout mice. J Comp Neurol (2005) 1.21
Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice. Cancer Res (2007) 1.21
Sunlight exposure and pathogenesis of uveal melanoma. Surv Ophthalmol (2004) 1.20
A family-based association study and gene expression analyses of netrin-G1 and -G2 genes in schizophrenia. Biol Psychiatry (2005) 1.20
Molecular and clinical spectrum of type I plasminogen deficiency: A series of 50 patients. Blood (2006) 1.20
Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain. J Biol Chem (2006) 1.19
Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice. Oncogene (2004) 1.19
BMPR1A signaling is necessary for hair follicle cycling and hair shaft differentiation in mice. Development (2004) 1.18
Matrix metalloproteinase-9 contributes to kindled seizure development in pentylenetetrazole-treated mice by converting pro-BDNF to mature BDNF in the hippocampus. J Neurosci (2011) 1.17
Bevacizumab for macular edema in central retinal vein occlusion: a prospective, randomized, double-masked clinical study. Ophthalmology (2012) 1.15
Physiological mouse brain Abeta levels are not related to the phosphorylation state of threonine-668 of Alzheimer's APP. PLoS One (2006) 1.14
Calcium-permeable AMPA receptors promote misfolding of mutant SOD1 protein and development of amyotrophic lateral sclerosis in a transgenic mouse model. Hum Mol Genet (2004) 1.12
The cut-and-paste method for primary pterygium surgery: long-term follow-up. Acta Ophthalmol Scand (2005) 1.12
Cortical adenylyl cyclase 1 is required for thalamocortical synapse maturation and aspects of layer IV barrel development. J Neurosci (2008) 1.11
Genetic dissection of medial habenula-interpeduncular nucleus pathway function in mice. Front Behav Neurosci (2013) 1.10
The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells. Clin Cancer Res (2006) 1.09
Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulation. Cell Mol Life Sci (2013) 1.08
Incidence of uveal melanoma in Sweden from 1960 to 1998. Invest Ophthalmol Vis Sci (2002) 1.08
Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway. Mol Cell Biol (2007) 1.08
S100B is increased in Parkinson's disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway. Brain (2012) 1.07
Efhc1 deficiency causes spontaneous myoclonus and increased seizure susceptibility. Hum Mol Genet (2009) 1.07
Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. Hum Mol Genet (2006) 1.06
Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. J Comp Neurol (2004) 1.04
The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model. EMBO J (2003) 1.04
DSCAM deficiency causes loss of pre-inspiratory neuron synchroneity and perinatal death. J Neurosci (2009) 1.04
Reduction of methamphetamine-induced sensitization and reward in matrix metalloproteinase-2 and -9-deficient mice. J Neurochem (2007) 1.01
Neural-activity-dependent release of S100B from astrocytes enhances kainate-induced gamma oscillations in vivo. J Neurosci (2008) 1.01
Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of D-serine, an N-methyl-D-aspartate receptor co-agonist, in adult brain. J Biol Chem (2010) 1.01
Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production. Mol Cell Biol (2013) 1.00
Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor. Invest Ophthalmol Vis Sci (2008) 0.99
Transgenic mice expressing a pH and Cl- sensing yellow-fluorescent protein under the control of a potassium channel promoter. Eur J Neurosci (2002) 0.99
Intratumoral forkhead box P3-positive regulatory T cells predict poor survival in cyclooxygenase-2-positive uveal melanoma. Cancer (2010) 0.98
Expression of Btcl2, a novel member of Btcl gene family, during development of the central nervous system. Brain Res Dev Brain Res (2004) 0.98
Inducible cAMP early repressor acts as a negative regulator for kindling epileptogenesis and long-term fear memory. J Neurosci (2008) 0.98
A novel gene, Btcl1, encoding CUB and LDLa domains is expressed in restricted areas of mouse brain. Biochem Biophys Res Commun (2003) 0.97
GABA and synaptic inhibition of mouse cerebellum lacking glutamate decarboxylase 67. Biochem Biophys Res Commun (2008) 0.97
Inhibition of obliterative airway disease development in murine tracheal allografts by matrix metalloproteinase-9 deficiency. Am J Transplant (2005) 0.97
Role of matrix metalloproteinase and tissue inhibitor of MMP in methamphetamine-induced behavioral sensitization and reward: implications for dopamine receptor down-regulation and dopamine release. J Neurochem (2007) 0.96
A prospective study on intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration of different durations. Acta Ophthalmol (2007) 0.96
Expression and prognostic significance of iNOS in uveal melanoma. Int J Cancer (2010) 0.96
NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling. J Neurosci (2011) 0.96
Astrocytic Ca2+ signals are required for the functional integrity of tripartite synapses. Mol Brain (2013) 0.95