Structure of a mitochondrial ribosome with minimal RNA.

PubWeight™: 1.38‹?› | Rank: Top 10%

🔗 View Article (PMC 2700991)

Published in Proc Natl Acad Sci U S A on June 03, 2009

Authors

Manjuli R Sharma1, Timothy M Booth, Larry Simpson, Dmitri A Maslov, Rajendra K Agrawal

Author Affiliations

1: Division of Translational Medicine, Wadsworth Center, New York State Department of Health, Empire State Plaza, Albany, NY 12201-0509, USA.

Articles citing this

Structure of the yeast mitochondrial large ribosomal subunit. Science (2014) 4.81

The ribosome challenge to the RNA world. J Mol Evol (2015) 2.10

Pentatricopeptide repeat proteins stimulate mRNA adenylation/uridylation to activate mitochondrial translation in trypanosomes. Mol Cell (2011) 2.10

Mitochondrial evolution. Cold Spring Harb Perspect Biol (2012) 1.64

Biological significance of 5S rRNA import into human mitochondria: role of ribosomal protein MRP-L18. Genes Dev (2011) 1.19

Cbp3-Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochrome b synthesis and assembly. J Cell Biol (2011) 1.12

Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. J Biol Chem (2010) 1.11

Extreme mitochondrial evolution in the ctenophore Mnemiopsis leidyi: Insight from mtDNA and the nuclear genome. Mitochondrial DNA (2011) 1.08

A universal RNA structural motif docking the elbow of tRNA in the ribosome, RNAse P and T-box leaders. Nucleic Acids Res (2013) 1.00

Structural aspects of mitochondrial translational apparatus. Curr Opin Struct Biol (2012) 1.00

Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit. Nucleic Acids Res (2011) 0.99

Mosaic nature of the mitochondrial proteome: Implications for the origin and evolution of mitochondria. Proc Natl Acad Sci U S A (2015) 0.99

Cryo-EM structure of the small subunit of the mammalian mitochondrial ribosome. Proc Natl Acad Sci U S A (2014) 0.98

Improved tRNA prediction in the American house dust mite reveals widespread occurrence of extremely short minimal tRNAs in acariform mites. BMC Genomics (2009) 0.95

The importance of the 45 S ribosomal small subunit-related complex for mitochondrial translation in Trypanosoma brucei. J Biol Chem (2013) 0.88

Genetic reconstruction of protozoan rRNA decoding sites provides a rationale for paromomycin activity against Leishmania and Trypanosoma. PLoS Negl Trop Dis (2011) 0.88

Mitochondrial ribosome assembly in health and disease. Cell Cycle (2015) 0.88

Kinetoplast DNA-encoded ribosomal protein S12: a possible functional link between mitochondrial RNA editing and translation in Trypanosoma brucei. RNA Biol (2013) 0.85

Widespread occurrence of organelle genome-encoded 5S rRNAs including permuted molecules. Nucleic Acids Res (2014) 0.83

Abundant 5S rRNA-like transcripts encoded by the mitochondrial genome in amoebozoa. Eukaryot Cell (2010) 0.82

Trans-splicing and RNA editing of LSU rRNA in Diplonema mitochondria. Nucleic Acids Res (2013) 0.82

Interaction of Streptococcus mutans YidC1 and YidC2 with translating and nontranslating ribosomes. J Bacteriol (2013) 0.81

The tRNA Elbow in Structure, Recognition and Evolution. Life (Basel) (2016) 0.81

Gene Loss and Error-Prone RNA Editing in the Mitochondrion of Perkinsela, an Endosymbiotic Kinetoplastid. MBio (2015) 0.81

Ribosome-associated pentatricopeptide repeat proteins function as translational activators in mitochondria of trypanosomes. Mol Microbiol (2016) 0.79

Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction. PLoS Genet (2015) 0.78

Biocrystallography: past, present, future. HFSP J (2010) 0.78

Molecular crowding inhibits U-insertion/deletion RNA editing in vitro: consequences for the in vivo reaction. PLoS One (2013) 0.78

Mitochondrial ribosomes in cancer. Semin Cancer Biol (2017) 0.76

A passion for parasites. J Biol Chem (2014) 0.76

Protein biosynthesis in mitochondria. Biochemistry (Mosc) (2013) 0.76

Trypanosome Mitochondrial Translation and Tetracycline: No Sweat about Tet. PLoS Pathog (2016) 0.75

High throughput gene complementation screening permits identification of a mammalian mitochondrial protein synthesis (ρ(-)) mutant. Biochim Biophys Acta (2016) 0.75

Articles cited by this

Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr A (1991) 119.63

Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res (2003) 77.89

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Science (2000) 28.25

Structure of the 30S ribosomal subunit. Nature (2000) 23.11

The structural basis of ribosome activity in peptide bond synthesis. Science (2000) 18.82

Crystal structure of the ribosome at 5.5 A resolution. Science (2001) 18.21

Structures of the bacterial ribosome at 3.5 A resolution. Science (2005) 12.63

Structure of the 70S ribosome complexed with mRNA and tRNA. Science (2006) 12.25

Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions. Cell (2001) 5.01

Solution structure of the E. coli 70S ribosome at 11.5 A resolution. Cell (2000) 3.99

Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy. Nat Struct Biol (2003) 3.77

Complex management: RNA editing in trypanosomes. Trends Biochem Sci (2005) 3.69

Structure of the mammalian mitochondrial ribosome reveals an expanded functional role for its component proteins. Cell (2003) 3.28

Simulating movement of tRNA into the ribosome during decoding. Proc Natl Acad Sci U S A (2005) 2.91

Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor. Cell (2004) 2.84

Structural basis for messenger RNA movement on the ribosome. Nature (2006) 2.55

Editing of kinetoplastid mitochondrial mRNAs by uridine addition and deletion generates conserved amino acid sequences and AUG initiation codons. Cell (1988) 2.32

Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastid flagellates. Curr Genet (2005) 2.01

Isolation of kinetoplast-mitochondrial complexes from Leishmania tarentolae. J Protozool (1974) 2.00

Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: functional implications. Proc Natl Acad Sci U S A (2004) 1.81

A minimal ribosomal RNA: sequence and secondary structure of the 9S kinetoplast ribosomal RNA from Leishmania tarentolae. Proc Natl Acad Sci U S A (1985) 1.76

Structure of keyhole limpet hemocyanin type 1 (KLH1) at 15 A resolution by electron cryomicroscopy and angular reconstitution. J Mol Biol (1997) 1.75

3' adenylation determines mRNA abundance and monitors completion of RNA editing in T. brucei mitochondria. EMBO J (2008) 1.63

Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle. J Cell Biol (2000) 1.60

Modeling a minimal ribosome based on comparative sequence analysis. J Mol Biol (2002) 1.58

Creation of AUG initiation codons by addition of uridines within cytochrome b transcripts of kinetoplastids. Proc Natl Acad Sci U S A (1988) 1.54

A structural model for the large subunit of the mammalian mitochondrial ribosome. J Mol Biol (2006) 1.46

Trypanosoma brucei mitochondrial ribosomes: affinity purification and component identification by mass spectrometry. Mol Cell Proteomics (2008) 1.44

Primary sequence and partial secondary structure of the 12S kinetoplast (mitochondrial) ribosomal RNA from Leishmania tarentolae: conservation of peptidyl-transferase structural elements. Nucleic Acids Res (1985) 1.39

Transcript-specific developmental regulation of polyadenylation in Trypanosoma brucei mitochondria. Mol Biochem Parasitol (1992) 1.39

Coordination of kRNA editing and polyadenylation in Trypanosoma brucei mitochondria: complete editing is not required for long poly(A) tract addition. Nucleic Acids Res (1999) 1.10

The origin and evolution of the ribosome. Biol Direct (2008) 1.10

Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins. Proc Natl Acad Sci U S A (2007) 1.07

Three-dimensional cryoelectron microscopy of ribosomes. Methods Enzymol (2000) 1.03

Isolation and characterization of mitochondrial ribosomes and ribosomal subunits from Leishmania tarentolae. Mol Biochem Parasitol (2006) 1.01

Terminal RNA uridylyltransferases of trypanosomes. Biochim Biophys Acta (2007) 0.98

Unusual polypeptide synthesis in the kinetoplast-mitochondria from Leishmania tarentolae. Identification of individual de novo translation products. J Biol Chem (2001) 0.97

Proteomics and electron microscopic characterization of the unusual mitochondrial ribosome-related 45S complex in Leishmania tarentolae. Mol Biochem Parasitol (2007) 0.92

Articles by these authors

Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process. EMBO J (2002) 3.57

Structure of the mammalian mitochondrial ribosome reveals an expanded functional role for its component proteins. Cell (2003) 3.28

Study of the structural dynamics of the E coli 70S ribosome using real-space refinement. Cell (2003) 3.03

Trypanosome mitochondrial 3' terminal uridylyl transferase (TUTase): the key enzyme in U-insertion/deletion RNA editing. Cell (2002) 2.28

Isolation of a U-insertion/deletion editing complex from Leishmania tarentolae mitochondria. EMBO J (2003) 2.12

Interaction of Era with the 30S ribosomal subunit implications for 30S subunit assembly. Mol Cell (2005) 1.93

A tale of two TUTases. Proc Natl Acad Sci U S A (2003) 1.87

Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: functional implications. Proc Natl Acad Sci U S A (2004) 1.81

A 100-kD complex of two RNA-binding proteins from mitochondria of Leishmania tarentolae catalyzes RNA annealing and interacts with several RNA editing components. RNA (2003) 1.79

Modeling a minimal ribosome based on comparative sequence analysis. J Mol Biol (2002) 1.58

Reconstitution of uridine-deletion precleaved RNA editing with two recombinant enzymes. Proc Natl Acad Sci U S A (2005) 1.47

A structural model for the large subunit of the mammalian mitochondrial ribosome. J Mol Biol (2006) 1.46

Interaction of the G' domain of elongation factor G and the C-terminal domain of ribosomal protein L7/L12 during translocation as revealed by cryo-EM. Mol Cell (2005) 1.38

Wobble modification differences and subcellular localization of tRNAs in Leishmania tarentolae: implication for tRNA sorting mechanism. EMBO J (2003) 1.37

Structural aspects of RbfA action during small ribosomal subunit assembly. Mol Cell (2007) 1.20

RNA-editing terminal uridylyl transferase 1: identification of functional domains by mutational analysis. J Biol Chem (2004) 1.16

Is the Trypanosoma brucei REL1 RNA ligase specific for U-deletion RNA editing, and is the REL2 RNA ligase specific for U-insertion editing? J Biol Chem (2003) 1.16

Monolithic microfluidic mixing-spraying devices for time-resolved cryo-electron microscopy. J Struct Biol (2009) 1.11

Reconstitution of full-round uridine-deletion RNA editing with three recombinant proteins. Proc Natl Acad Sci U S A (2006) 1.11

Does linezolid cause lactic acidosis by inhibiting mitochondrial protein synthesis? Clin Infect Dis (2005) 1.08

Progression of the ribosome recycling factor through the ribosome dissociates the two ribosomal subunits. Mol Cell (2007) 1.08

Trypanosome REH1 is an RNA helicase involved with the 3'-5' polarity of multiple gRNA-guided uridine insertion/deletion RNA editing. Proc Natl Acad Sci U S A (2011) 1.07

Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins. Proc Natl Acad Sci U S A (2007) 1.07

Multiple terminal uridylyltransferases of trypanosomes. FEBS Lett (2004) 1.07

A single mammalian mitochondrial translation initiation factor functionally replaces two bacterial factors. Mol Cell (2008) 1.06

Modification of the universally unmodified uridine-33 in a mitochondria-imported edited tRNA and the role of the anticodon arm structure on editing efficiency. RNA (2002) 1.05

Uridylate-specific 3' 5'-exoribonucleases involved in uridylate-deletion RNA editing in trypanosomatid mitochondria. J Biol Chem (2007) 1.04

Guide to the nomenclature of kinetoplastid RNA editing: a proposal. Protist (2009) 1.03

Structure of the core editing complex (L-complex) involved in uridine insertion/deletion RNA editing in trypanosomatid mitochondria. Proc Natl Acad Sci U S A (2009) 1.02

Uridine insertion/deletion RNA editing in trypanosomatid mitochondria: In search of the editosome. RNA (2009) 1.02

Isolation and characterization of mitochondrial ribosomes and ribosomal subunits from Leishmania tarentolae. Mol Biochem Parasitol (2006) 1.01

Genomic organization of Trypanosoma brucei kinetoplast DNA minicircles. Protist (2003) 1.01

The effect of RNA interference Down-regulation of RNA editing 3'-terminal uridylyl transferase (TUTase) 1 on mitochondrial de novo protein synthesis and stability of respiratory complexes in Trypanosoma brucei. J Biol Chem (2003) 1.00

PSRP1 is not a ribosomal protein, but a ribosome-binding factor that is recycled by the ribosome-recycling factor (RRF) and elongation factor G (EF-G). J Biol Chem (2009) 0.99

What happens when Trypanosoma brucei leaves Africa. Trends Parasitol (2008) 0.99

Structural insights into initial and intermediate steps of the ribosome-recycling process. EMBO J (2012) 0.99

Disruption of the zinc finger motifs in the Leishmania tarentolae LC-4 (=TbMP63) L-complex editing protein affects the stability of the L-complex. J Biol Chem (2003) 0.99

Unusual polypeptide synthesis in the kinetoplast-mitochondria from Leishmania tarentolae. Identification of individual de novo translation products. J Biol Chem (2001) 0.97

Mitochondrial protein import pathways are functionally conserved among eukaryotes despite compositional diversity of the import machineries. Biol Chem (2012) 0.96

Differential localization of nuclear-encoded tRNAs between the cytosol and mitochondrion in Leishmania tarentolae. RNA (2002) 0.94

Proteomics and electron microscopic characterization of the unusual mitochondrial ribosome-related 45S complex in Leishmania tarentolae. Mol Biochem Parasitol (2007) 0.92

RBP38, a novel RNA-binding protein from trypanosomatid mitochondria, modulates RNA stability. Eukaryot Cell (2003) 0.90

Cosmopolitan distribution of a trypanosomatid Leptomonas pyrrhocoris. Protist (2012) 0.89

The importance of the 45 S ribosomal small subunit-related complex for mitochondrial translation in Trypanosoma brucei. J Biol Chem (2013) 0.88

Functional complementation of Trypanosoma brucei RNA in vitro editing with recombinant RNA ligase. Proc Natl Acad Sci U S A (2005) 0.88

Probing for primary functions of prohibitin in Trypanosoma brucei. Int J Parasitol (2009) 0.87

Insertion domain within mammalian mitochondrial translation initiation factor 2 serves the role of eubacterial initiation factor 1. Proc Natl Acad Sci U S A (2011) 0.86

An integrated morphological and molecular approach to a new species description in the Trypanosomatidae: the case of Leptomonas podlipaevi n. sp., a parasite of Boisea rubrolineata (Hemiptera: Rhopalidae). J Eukaryot Microbiol (2006) 0.86

Probing into the diversity of trypanosomatid flagellates parasitizing insect hosts in South-West China reveals both endemism and global dispersal. Mol Phylogenet Evol (2009) 0.86

NADH-ubiquinone oxidoreductase activity in the kinetoplasts of the plant trypanosomatid Phytomonas serpens. Parasitol Res (2004) 0.83

New species of insect trypanosomatids from Costa Rica and the proposal for a new subfamily within the Trypanosomatidae. J Eukaryot Microbiol (2012) 0.83

Anatomy-based inverse planning simulated annealing optimization in high-dose-rate prostate brachytherapy: significant dosimetric advantage over other optimization techniques. Int J Radiat Oncol Biol Phys (2008) 0.82

Strategies of kinetoplastid cryptogene discovery and analysis. Methods Enzymol (2007) 0.82

Uridine insertion/deletion RNA editing in Trypanosomatids: specific stimulation in vitro of Leishmania tarentolae REL1 RNA ligase activity by the MP63 zinc finger protein. Protist (2010) 0.81

Selective recovery of the cultivation-prone components from mixed trypanosomatid infections: a case of several novel species isolated from Neotropical Heteroptera. Int J Syst Evol Microbiol (2009) 0.81

Morphological discordance of the new trypanosomatid species phylogenetically associated with the genus crithidia. Protist (2007) 0.81

The I-complex in Leishmania tarentolae is an uniquely-structured F(1)-ATPase. Mol Biochem Parasitol (2004) 0.80

Malaria, not down and certainly not out. Am J Trop Med Hyg (2005) 0.80

A quality assurance method with submillimeter accuracy for stereotactic linear accelerators. J Appl Clin Med Phys (2010) 0.80

Microbotryozyma collariae gen. nov., sp. nov., a basidiomycetous yeast isolated from a plant bug Collaria oleosa (Miridae). Antonie Van Leeuwenhoek (2012) 0.78

Cloning, characterization and preliminary crystallographic analysis of Leishmania hypoxanthine-guanine phosphoribosyltransferase. Biochim Biophys Acta (2002) 0.77

RNA editing and mitochondrial activity in promastigotes and amastigotes of Leishmania donovani. Int J Parasitol (2008) 0.77

Computational exploration of structural hypotheses for an additional sequence in a mammalian mitochondrial protein. PLoS One (2011) 0.77

Problems with the transorientation hypothesis. RNA (2002) 0.75

Science is a hard mistress. Protist (2009) 0.75

Musings on the real problems. Protist (2008) 0.75