Published in Proc Natl Acad Sci U S A on January 18, 2005
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An essential RNase III insertion editing endonuclease in Trypanosoma brucei. Proc Natl Acad Sci U S A (2005) 1.96
RNA editing in Trypanosoma brucei requires three different editosomes. Mol Cell Biol (2007) 1.87
Compositionally and functionally distinct editosomes in Trypanosoma brucei. RNA (2006) 1.86
Comparative proteogenomics: combining mass spectrometry and comparative genomics to analyze multiple genomes. Genome Res (2008) 1.68
Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei. EMBO J (2005) 1.61
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KREPA4, an RNA binding protein essential for editosome integrity and survival of Trypanosoma brucei. RNA (2006) 1.19
KREPA6 is an RNA-binding protein essential for editosome integrity and survival of Trypanosoma brucei. RNA (2007) 1.14
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An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei. RNA (2007) 1.08
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Endonuclease associations with three distinct editosomes in Trypanosoma brucei. J Biol Chem (2011) 1.07
Differential functions of two editosome exoUases in Trypanosoma brucei. RNA (2009) 1.06
RBP16 stimulates trypanosome RNA editing in vitro at an early step in the editing reaction. RNA (2006) 1.06
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Novel TUTase associates with an editosome-like complex in mitochondria of Trypanosoma brucei. RNA (2009) 0.99
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Crystal structure of a heterodimer of editosome interaction proteins in complex with two copies of a cross-reacting nanobody. Nucleic Acids Res (2011) 0.97
RNA-level unscrambling of fragmented genes in Diplonema mitochondria. RNA Biol (2013) 0.95
In Trypanosoma brucei RNA editing, TbMP18 (band VII) is critical for editosome integrity and for both insertional and deletional cleavages. Mol Cell Biol (2006) 0.92
RNA editing complex interactions with a site for full-round U deletion in Trypanosoma brucei. RNA (2006) 0.92
The zinc-fingers of KREPA3 are essential for the complete editing of mitochondrial mRNAs in Trypanosoma brucei. PLoS One (2010) 0.89
Functional complementation of Trypanosoma brucei RNA in vitro editing with recombinant RNA ligase. Proc Natl Acad Sci U S A (2005) 0.88
TbMP42 is a structure-sensitive ribonuclease that likely follows a metal ion catalysis mechanism. Nucleic Acids Res (2008) 0.88
Trypanosoma brucei RNA editing: coupled cycles of U deletion reveal processive activity of the editing complex. Mol Cell Biol (2008) 0.87
Naphthalene-based RNA editing inhibitor blocks RNA editing activities and editosome assembly in Trypanosoma brucei. J Biol Chem (2011) 0.87
Determinants for association and guide RNA-directed endonuclease cleavage by purified RNA editing complexes from Trypanosoma brucei. J Mol Biol (2008) 0.87
A novel member of the RNase D exoribonuclease family functions in mitochondrial guide RNA metabolism in Trypanosoma brucei. J Biol Chem (2011) 0.86
Kinetoplastid RNA editing involves a 3' nucleotidyl phosphatase activity. Nucleic Acids Res (2009) 0.85
Mechanism of U insertion RNA editing in trypanosome mitochondria: the bimodal TUTase activity of the core complex. J Mol Biol (2010) 0.85
OB-fold domain of KREPA4 mediates high-affinity interaction with guide RNA and possesses annealing activity. RNA (2010) 0.85
KREX2 is not essential for either procyclic or bloodstream form Trypanosoma brucei. PLoS One (2012) 0.84
Trypanosoma brucei ATPase subunit 6 mRNA bound to gA6-14 forms a conserved three-helical structure. RNA (2008) 0.84
Uridine insertion/deletion RNA editing in Trypanosomatids: specific stimulation in vitro of Leishmania tarentolae REL1 RNA ligase activity by the MP63 zinc finger protein. Protist (2010) 0.81
Inhibitors of RNA editing as potential chemotherapeutics against trypanosomatid pathogens. Int J Parasitol Drugs Drug Resist (2011) 0.81
Taking U out, with two nucleases? BMC Bioinformatics (2006) 0.80
In vivo cleavage specificity of Trypanosoma brucei editosome endonucleases. Nucleic Acids Res (2017) 0.75
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A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei. Mol Biochem Parasitol (1999) 11.77
An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma brucei. Science (2001) 3.52
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RNA ligase and its involvement in guide RNA/mRNA chimera formation. Evidence for a cleavage-ligation mechanism of Trypanosoma brucei mRNA editing. J Biol Chem (1995) 2.46
Identification of novel components of Trypanosoma brucei editosomes. RNA (2003) 2.30
Trypanosome mitochondrial 3' terminal uridylyl transferase (TUTase): the key enzyme in U-insertion/deletion RNA editing. Cell (2002) 2.28
Uridylate addition and RNA ligation contribute to the specificity of kinetoplastid insertion RNA editing. Mol Cell Biol (2000) 2.20
Double-stranded RNA interference in Trypanosoma brucei using head-to-head promoters. Mol Biochem Parasitol (2000) 2.15
Identification of candidate mitochondrial RNA editing ligases from Trypanosoma brucei. RNA (2001) 2.15
Isolation of a U-insertion/deletion editing complex from Leishmania tarentolae mitochondria. EMBO J (2003) 2.12
Mitochondrial proteins and complexes in Leishmania and Trypanosoma involved in U-insertion/deletion RNA editing. RNA (2004) 2.06
The two RNA ligases of the Trypanosoma brucei RNA editing complex: cloning the essential band IV gene and identifying the band V gene. Mol Cell Biol (2001) 2.05
Isolation of kinetoplast-mitochondrial complexes from Leishmania tarentolae. J Protozool (1974) 2.00
Uridine insertion/deletion RNA editing in trypanosome mitochondria--a review. Gene (1999) 1.99
The polarity of editing within a multiple gRNA-mediated domain is due to formation of anchors for upstream gRNAs by downstream editing. Cell (1992) 1.99
Separate insertion and deletion subcomplexes of the Trypanosoma brucei RNA editing complex. Mol Cell (2003) 1.94
TbMP57 is a 3' terminal uridylyl transferase (TUTase) of the Trypanosoma brucei editosome. Mol Cell (2003) 1.88
A tale of two TUTases. Proc Natl Acad Sci U S A (2003) 1.87
T. brucei RNA editing: adenosine nucleotides inversely affect U-deletion and U-insertion reactions at mRNA cleavage. Mol Cell (1998) 1.78
Roles for ligases in the RNA editing complex of Trypanosoma brucei: band IV is needed for U-deletion and RNA repair. EMBO J (2001) 1.70
Comparative analysis of editosome proteins in trypanosomatids. Nucleic Acids Res (2003) 1.52
Distinct functions of two RNA ligases in active Trypanosoma brucei RNA editing complexes. Mol Cell Biol (2002) 1.48
Native gel analysis of ribonucleoprotein complexes from a Leishmania tarentolae mitochondrial extract. Mol Biochem Parasitol (1997) 1.38
Mass spectrometric analysis of the editosome and other multiprotein complexes in Trypanosoma brucei. J Am Soc Mass Spectrom (2003) 1.35
Is the Trypanosoma brucei REL1 RNA ligase specific for U-deletion RNA editing, and is the REL2 RNA ligase specific for U-insertion editing? J Biol Chem (2003) 1.16
Matrix-assisted laser desorption/ionization-tandem mass spectrometry with high resolution and sensitivity for identification and characterization of proteins. Proteomics (2002) 1.08
The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway. Science (2006) 3.64
The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies. Proc Natl Acad Sci U S A (2003) 3.52
A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress. Cell (2012) 3.27
Role for a Drosophila Myb-containing protein complex in site-specific DNA replication. Nature (2002) 2.61
TRF2 associates with DREF and directs promoter-selective gene expression in Drosophila. Nature (2002) 2.48
Spider toxins activate the capsaicin receptor to produce inflammatory pain. Nature (2006) 2.47
High yield bacterial expression of active c-Abl and c-Src tyrosine kinases. Protein Sci (2005) 2.32
Trypanosome mitochondrial 3' terminal uridylyl transferase (TUTase): the key enzyme in U-insertion/deletion RNA editing. Cell (2002) 2.28
Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases. Nat Struct Biol (2003) 2.27
Isolation of a U-insertion/deletion editing complex from Leishmania tarentolae mitochondria. EMBO J (2003) 2.12
Mitochondrial proteins and complexes in Leishmania and Trypanosoma involved in U-insertion/deletion RNA editing. RNA (2004) 2.06
Polypyrimidine tract binding protein blocks the 5' splice site-dependent assembly of U2AF and the prespliceosomal E complex. Mol Cell (2005) 2.05
A tale of two TUTases. Proc Natl Acad Sci U S A (2003) 1.87
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain. Nature (2011) 1.84
A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain. Cell (2010) 1.82
N-terminal processing of proteins exported by malaria parasites. Mol Biochem Parasitol (2008) 1.81
Guide RNA-binding complex from mitochondria of trypanosomatids. Mol Cell (2008) 1.75
The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator. Proc Natl Acad Sci U S A (2004) 1.70
Characterization of embryonic globin genes of the zebrafish. Dev Biol (2003) 1.65
Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors. J Biol Chem (2002) 1.61
Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-strand break repair. Mol Cell (2006) 1.54
The Association of Biomolecular Resource Facilities Proteomics Research Group 2006 study: relative protein quantitation. Mol Cell Proteomics (2007) 1.53
HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim. EMBO J (2002) 1.50
The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines. J Biol Chem (2005) 1.50
A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria. Sci Signal (2012) 1.41
Structure of a mitochondrial ribosome with minimal RNA. Proc Natl Acad Sci U S A (2009) 1.38
Wobble modification differences and subcellular localization of tRNAs in Leishmania tarentolae: implication for tRNA sorting mechanism. EMBO J (2003) 1.37
M. tuberculosis Ser/Thr protein kinase D phosphorylates an anti-anti-sigma factor homolog. PLoS Pathog (2007) 1.28
Pyriform spidroin 1, a novel member of the silk gene family that anchors dragline silk fibers in attachment discs of the black widow spider, Latrodectus hesperus. J Biol Chem (2009) 1.24
Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner. Mol Cell Biol (2003) 1.21
RNA-editing terminal uridylyl transferase 1: identification of functional domains by mutational analysis. J Biol Chem (2004) 1.16
Is the Trypanosoma brucei REL1 RNA ligase specific for U-deletion RNA editing, and is the REL2 RNA ligase specific for U-insertion editing? J Biol Chem (2003) 1.16
Energetics-based protein profiling on a proteomic scale: identification of proteins resistant to proteolysis. J Mol Biol (2007) 1.15
Reconstitution of full-round uridine-deletion RNA editing with three recombinant proteins. Proc Natl Acad Sci U S A (2006) 1.11
Trypanosome REH1 is an RNA helicase involved with the 3'-5' polarity of multiple gRNA-guided uridine insertion/deletion RNA editing. Proc Natl Acad Sci U S A (2011) 1.07
Multiple terminal uridylyltransferases of trypanosomes. FEBS Lett (2004) 1.07
Uridylate-specific 3' 5'-exoribonucleases involved in uridylate-deletion RNA editing in trypanosomatid mitochondria. J Biol Chem (2007) 1.04
Guide to the nomenclature of kinetoplastid RNA editing: a proposal. Protist (2009) 1.03
Structure of the core editing complex (L-complex) involved in uridine insertion/deletion RNA editing in trypanosomatid mitochondria. Proc Natl Acad Sci U S A (2009) 1.02
Uridine insertion/deletion RNA editing in trypanosomatid mitochondria: In search of the editosome. RNA (2009) 1.02
Genomic organization of Trypanosoma brucei kinetoplast DNA minicircles. Protist (2003) 1.01
Isolation and characterization of mitochondrial ribosomes and ribosomal subunits from Leishmania tarentolae. Mol Biochem Parasitol (2006) 1.01
The effect of RNA interference Down-regulation of RNA editing 3'-terminal uridylyl transferase (TUTase) 1 on mitochondrial de novo protein synthesis and stability of respiratory complexes in Trypanosoma brucei. J Biol Chem (2003) 1.00
Aciniform spidroin, a constituent of egg case sacs and wrapping silk fibers from the black widow spider Latrodectus hesperus. J Biol Chem (2007) 1.00
Analysis of aqueous glue coating proteins on the silk fibers of the cob weaver, Latrodectus hesperus. Biochemistry (2007) 1.00
What happens when Trypanosoma brucei leaves Africa. Trends Parasitol (2008) 0.99
Disruption of the zinc finger motifs in the Leishmania tarentolae LC-4 (=TbMP63) L-complex editing protein affects the stability of the L-complex. J Biol Chem (2003) 0.99
Araneoid egg case silk: a fibroin with novel ensemble repeat units from the black widow spider, Latrodectus hesperus. Biochemistry (2005) 0.99
Egg case protein-1. A new class of silk proteins with fibroin-like properties from the spider Latrodectus hesperus. J Biol Chem (2005) 0.98
Mitochondrial protein import pathways are functionally conserved among eukaryotes despite compositional diversity of the import machineries. Biol Chem (2012) 0.96
Differential localization of nuclear-encoded tRNAs between the cytosol and mitochondrion in Leishmania tarentolae. RNA (2002) 0.94
Proteomics and electron microscopic characterization of the unusual mitochondrial ribosome-related 45S complex in Leishmania tarentolae. Mol Biochem Parasitol (2007) 0.92
Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB. Structure (2010) 0.90
RBP38, a novel RNA-binding protein from trypanosomatid mitochondria, modulates RNA stability. Eukaryot Cell (2003) 0.90
Spider minor ampullate silk proteins are constituents of prey wrapping silk in the cob weaver Latrodectus hesperus. Biochemistry (2008) 0.90
Spider egg case core fibers: trimeric complexes assembled from TuSp1, ECP-1, and ECP-2. Biochemistry (2006) 0.89
Nuclear respiratory factor 1 plays an essential role in transcriptional initiation from the hepatitis B virus x gene promoter. J Virol (2004) 0.89
Functional complementation of Trypanosoma brucei RNA in vitro editing with recombinant RNA ligase. Proc Natl Acad Sci U S A (2005) 0.88
Proteome of Haemophilus ducreyi by 2-D SDS-PAGE and mass spectrometry: strain variation, virulence, and carbohydrate expression. J Proteome Res (2003) 0.87
Nuclear localization of the DOCK180/ELMO complex. Arch Biochem Biophys (2004) 0.86
Measurement of solvent accessibility at protein-protein interfaces. Methods Mol Biol (2005) 0.85
Spider glue proteins have distinct architectures compared with traditional spidroin family members. J Biol Chem (2012) 0.82
Strategies of kinetoplastid cryptogene discovery and analysis. Methods Enzymol (2007) 0.82
Anatomy-based inverse planning simulated annealing optimization in high-dose-rate prostate brachytherapy: significant dosimetric advantage over other optimization techniques. Int J Radiat Oncol Biol Phys (2008) 0.82
The cyclobutane dimers of 5-methylcytosine and their deamination products. Photochem Photobiol Sci (2004) 0.81
Uridine insertion/deletion RNA editing in Trypanosomatids: specific stimulation in vitro of Leishmania tarentolae REL1 RNA ligase activity by the MP63 zinc finger protein. Protist (2010) 0.81
The I-complex in Leishmania tarentolae is an uniquely-structured F(1)-ATPase. Mol Biochem Parasitol (2004) 0.80
A quality assurance method with submillimeter accuracy for stereotactic linear accelerators. J Appl Clin Med Phys (2010) 0.80
Malaria, not down and certainly not out. Am J Trop Med Hyg (2005) 0.80
Diversity of aspartate carbamoyltransferase genes of Trypanosoma cruzi. Int J Parasitol (2003) 0.78
Application of amide proton exchange mass spectrometry for the study of protein-protein interactions. Curr Protoc Protein Sci (2005) 0.78
Cloning, characterization and preliminary crystallographic analysis of Leishmania hypoxanthine-guanine phosphoribosyltransferase. Biochim Biophys Acta (2002) 0.77
RNA editing and mitochondrial activity in promastigotes and amastigotes of Leishmania donovani. Int J Parasitol (2008) 0.77
Musings on the real problems. Protist (2008) 0.75
Mass spectrometry of murine leukemia virus core proteins. J Virol Methods (2010) 0.75
Science is a hard mistress. Protist (2009) 0.75