PubRank

Walter J Chazin

Author PubWeight™ 127.92‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Metal chelation and inhibition of bacterial growth in tissue abscesses. Science 2008 4.55
2 Calmodulin mutations associated with recurrent cardiac arrest in infants. Circulation 2013 2.66
3 Nutrient metal sequestration by calprotectin inhibits bacterial superoxide defense, enhancing neutrophil killing of Staphylococcus aureus. Cell Host Microbe 2011 2.66
4 Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut. Cell Host Microbe 2012 2.66
5 Structural insights into the U-box, a domain associated with multi-ubiquitination. Nat Struct Biol 2003 2.26
6 The basic cleft of RPA70N binds multiple checkpoint proteins, including RAD9, to regulate ATR signaling. Mol Cell Biol 2008 2.17
7 Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases. Mol Cell 2012 2.07
8 Function of a conserved checkpoint recruitment domain in ATRIP proteins. Mol Cell Biol 2007 2.02
9 S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway. J Leukoc Biol 2008 1.82
10 Target selectivity in EF-hand calcium binding proteins. Biochim Biophys Acta 2004 1.72
11 An iron-sulfur cluster in the C-terminal domain of the p58 subunit of human DNA primase. J Biol Chem 2007 1.71
12 The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in rheumatoid arthritis. Arthritis Res Ther 2006 1.67
13 Physical interaction between replication protein A and Rad51 promotes exchange on single-stranded DNA. J Biol Chem 2004 1.65
14 Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens. Proc Natl Acad Sci U S A 2013 1.64
15 Independent and coordinated functions of replication protein A tandem high affinity single-stranded DNA binding domains. J Biol Chem 2003 1.59
16 An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability. Nat Struct Mol Biol 2004 1.59
17 Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain. J Biol Chem 2004 1.52
18 The extracellular region of the receptor for advanced glycation end products is composed of two independent structural units. Biochemistry 2007 1.51
19 Structural basis for ligand recognition and activation of RAGE. Structure 2010 1.50
20 Insights into hRPA32 C-terminal domain--mediated assembly of the simian virus 40 replisome. Nat Struct Mol Biol 2005 1.50
21 Identification of an Acinetobacter baumannii zinc acquisition system that facilitates resistance to calprotectin-mediated zinc sequestration. PLoS Pathog 2012 1.47
22 Calcium-modulated S100 protein-phospholipid interactions. An NMR study of calbindin D9k and DPC. Biochemistry 2005 1.46
23 Structural mechanisms of DNA replication, repair, and recombination. J Biol Chem 2004 1.46
24 Structural and functional analysis of essential pre-mRNA splicing factor Prp19p. Mol Cell Biol 2005 1.42
25 S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3. Cell Res 2009 1.42
26 Structure-function analysis of inositol hexakisphosphate-induced autoprocessing in Clostridium difficile toxin A. J Biol Chem 2009 1.39
27 The Prp19 U-box crystal structure suggests a common dimeric architecture for a class of oligomeric E3 ubiquitin ligases. Biochemistry 2006 1.38
28 Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switch. Proc Natl Acad Sci U S A 2006 1.36
29 The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements. Mol Endocrinol 2005 1.34
30 Solution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5. J Mol Biol 2010 1.32
31 Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5. J Biol Chem 2008 1.32
32 Structure of the Ca2+/S100B/NDR kinase peptide complex: insights into S100 target specificity and activation of the kinase. Biochemistry 2003 1.30
33 Novel calmodulin mutations associated with congenital arrhythmia susceptibility. Circ Cardiovasc Genet 2014 1.27
34 Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants. Circ Res 2014 1.27
35 Structural mechanism of RPA loading on DNA during activation of a simple pre-replication complex. EMBO J 2006 1.25
36 S100A8/A9: a Janus-faced molecule in cancer therapy and tumorgenesis. Eur J Pharmacol 2009 1.24
37 Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin. J Biol Chem 2009 1.22
38 Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase. Proc Natl Acad Sci U S A 2010 1.21
39 Checkpoint kinase ATR promotes nucleotide excision repair of UV-induced DNA damage via physical interaction with xeroderma pigmentosum group A. J Biol Chem 2009 1.19
40 S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2. Biochim Biophys Acta 2007 1.19
41 Direct ubiquitination of beta-catenin by Siah-1 and regulation by the exchange factor TBL1. J Biol Chem 2010 1.18
42 MntABC and MntH contribute to systemic Staphylococcus aureus infection by competing with calprotectin for nutrient manganese. Infect Immun 2013 1.17
43 The EF-hand domain: a globally cooperative structural unit. Protein Sci 2002 1.17
44 Structural basis for DNA binding by replication initiator Mcm10. Structure 2008 1.14
45 A new structural framework for integrating replication protein A into DNA processing machinery. Nucleic Acids Res 2013 1.12
46 In support of the BMRB. Nat Struct Mol Biol 2012 1.09
47 Unique features in the C-terminal domain provide caltractin with target specificity. J Mol Biol 2003 1.09
48 NMR analysis of the architecture and functional remodeling of a modular multidomain protein, RPA. J Am Chem Soc 2009 1.08
49 Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling. J Exp Med 2012 1.07
50 Stable RAGE-heparan sulfate complexes are essential for signal transduction. ACS Chem Biol 2013 1.07
51 Alpha4 is a ubiquitin-binding protein that regulates protein serine/threonine phosphatase 2A ubiquitination. Biochemistry 2010 1.06
52 Biochemical and structural domain analysis of xeroderma pigmentosum complementation group C protein. Biochemistry 2006 1.05
53 Structural dynamics and single-stranded DNA binding activity of the three N-terminal domains of the large subunit of replication protein A from small angle X-ray scattering. Biochemistry 2010 1.04
54 Structure of the S100A6 complex with a fragment from the C-terminal domain of Siah-1 interacting protein: a novel mode for S100 protein target recognition. Biochemistry 2008 1.04
55 Implication of extracellular zinc exclusion by recombinant human calprotectin (MRP8 and MRP14) from target cells in its apoptosis-inducing activity. Mediators Inflamm 2002 1.03
56 A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A. Anal Biochem 2011 1.03
57 Engineering and design of ligand-induced conformational change in proteins. Curr Opin Struct Biol 2002 1.02
58 Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition. J Mol Biol 2005 1.01
59 Structural and functional characterization of the monomeric U-box domain from E4B. Biochemistry 2010 1.01
60 Calmodulin interacts with the V2 vasopressin receptor: elimination of binding to the C terminus also eliminates arginine vasopressin-stimulated elevation of intracellular calcium. J Biol Chem 2004 1.00
61 Physical interactions between Mcm10, DNA, and DNA polymerase alpha. J Biol Chem 2009 0.99
62 Discovery of a potent stapled helix peptide that binds to the 70N domain of replication protein A. J Med Chem 2014 0.97
63 E2 conjugating enzyme selectivity and requirements for function of the E3 ubiquitin ligase CHIP. J Biol Chem 2011 0.97
64 Structure of the N-terminal calcium sensor domain of centrin reveals the biochemical basis for domain-specific function. J Biol Chem 2005 0.96
65 Regulation of S100A8/A9 (calprotectin) binding to tumor cells by zinc ion and its implication for apoptosis-inducing activity. Mediators Inflamm 2005 0.96
66 The mode of action of centrin. Binding of Ca2+ and a peptide fragment of Kar1p to the C-terminal domain. J Biol Chem 2004 0.95
67 Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A. ACS Med Chem Lett 2013 0.95
68 Designing sequence to control protein function in an EF-hand protein. J Am Chem Soc 2004 0.95
69 Evidence for differing roles for each lobe of the calmodulin-like domain in a calcium-dependent protein kinase. J Biol Chem 2004 0.94
70 Engineering a ubiquitin ligase reveals conformational flexibility required for ubiquitin transfer. J Biol Chem 2009 0.94
71 Activation of UbcH5c~Ub is the result of a shift in interdomain motions of the conjugate bound to U-box E3 ligase E4B. Biochemistry 2013 0.94
72 Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma. PLoS One 2013 0.93
73 Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approach. J Med Chem 2013 0.93
74 Structural independence of the two EF-hand domains of caltractin. J Biol Chem 2002 0.93
75 The modular structure of SIP facilitates its role in stabilizing multiprotein assemblies. Biochemistry 2005 0.92
76 BID binds to replication protein A and stimulates ATR function following replicative stress. Mol Cell Biol 2011 0.91
77 A structural basis for S100 protein specificity derived from comparative analysis of apo and Ca(2+)-calcyclin. J Mol Biol 2002 0.91
78 Zinc piracy as a mechanism of Neisseria meningitidis for evasion of nutritional immunity. PLoS Pathog 2013 0.91
79 Replication protein A stimulates the Werner syndrome protein branch migration activity. J Biol Chem 2009 0.90
80 Solution NMR structure of the C-terminal DNA binding domain of Mcm10 reveals a conserved MCM motif. J Biol Chem 2010 0.90
81 Na+ channel function, regulation, structure, trafficking and sequestration. J Physiol 2015 0.88
82 Xeroderma pigmentosum complementation group C protein (XPC) serves as a general sensor of damaged DNA. DNA Repair (Amst) 2013 0.88
83 The Prp19 WD40 domain contains a conserved protein interaction region essential for its function. Structure 2010 0.88
84 Human DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress. J Biol Chem 2011 0.87
85 The biochemical effect of Ser167 phosphorylation on Chlamydomonas reinhardtii centrin. Biochem Biophys Res Commun 2006 0.86
86 Dynamics of hydrogen-deuterium exchange in Chlamydomonas centrin. Biochemistry 2005 0.86
87 S100 calcium binding proteins and ion channels. Front Pharmacol 2012 0.86
88 Characterization of binding-induced changes in dynamics suggests a model for sequence-nonspecific binding of ssDNA by replication protein A. Protein Sci 2002 0.86
89 NMR study on the interaction between RPA and DNA decamer containing cis-syn cyclobutane pyrimidine dimer in the presence of XPA: implication for damage verification and strand-specific dual incision in nucleotide excision repair. Nucleic Acids Res 2003 0.85
90 Structure of a DNA polymerase alpha-primase domain that docks on the SV40 helicase and activates the viral primosome. J Biol Chem 2010 0.85
91 Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication protein A interaction motif of ATR interacting protein. Biochemistry 2013 0.84
92 Redefining the DNA-binding domain of human XPA. J Am Chem Soc 2014 0.83
93 Structural analysis of replication protein A recruitment of the DNA damage response protein SMARCAL1. Biochemistry 2014 0.83
94 Effects of calcium binding on the side-chain methyl dynamics of calbindin D9k: a 2H NMR relaxation study. J Mol Biol 2006 0.83
95 Calcium-driven changes in S100A11 structure revealed. Structure 2003 0.81
96 1H, 13C and 15N assignments of single-stranded DNA binding domains from the 70 kDa subunit of human replication protein A. J Biomol NMR 2004 0.81
97 Inhibition of bacterial superoxide defense: a new front in the struggle between host and pathogen. Virulence 2012 0.79
98 Nascent structure in the kinase anchoring domain of microtubule-associated protein 2. Biochem Biophys Res Commun 2003 0.79
99 Binding to retinoblastoma pocket domain does not alter the inter-domain flexibility of the J domain of SV40 large T antigen. Arch Biochem Biophys 2011 0.78
100 NMR structure of the (+)-CPI-indole/d(GACTAATTGAC)-d(GTCAATTAGTC) covalent complex. Chembiochem 2003 0.78
101 Preparation of the modular multi-domain protein RPA for study by NMR spectroscopy. Methods Mol Biol 2012 0.78
102 XPF-ERCC1: on the bubble. Structure 2012 0.77
103 Erratum: Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection. Nat Med 2016 0.76
104 NMR studies of the interaction of calmodulin with IQ motif peptides. Methods Mol Biol 2013 0.76
105 Sample preparation methods to analyze DNA-induced structural changes in replication protein A. Methods Mol Biol 2012 0.76
106 Protein modification by adenine propenal. Chem Res Toxicol 2014 0.76
107 Two blades of the [ex]scissor. Structure 2005 0.75
108 Calmodulin Mutants Linked to Catecholaminergic Polymorphic Ventricular Tachycardia Fail to Inhibit Human RyR2 Channels. J Am Coll Cardiol 2017 0.75
109 1H, 15N and 13C assignments of the regulatory domains of calcium-dependent protein kinase (CDPK). J Biomol NMR 2002 0.75