Published in Mol Cell Biol on October 20, 2008
ATR signalling: more than meeting at the fork. Biochem J (2011) 2.37
PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry. Mol Cell (2013) 1.95
Replication protein A: directing traffic at the intersection of replication and repair. Front Biosci (Landmark Ed) (2010) 1.77
Common mechanisms of PIKK regulation. DNA Repair (Amst) (2009) 1.73
Telomere protection by TPP1/POT1 requires tethering to TIN2. Mol Cell (2011) 1.62
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling. Proc Natl Acad Sci U S A (2010) 1.53
hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity. EMBO Rep (2013) 1.49
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response. EMBO Rep (2010) 1.36
A role for the MRN complex in ATR activation via TOPBP1 recruitment. Mol Cell (2013) 1.31
Oligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardians. Crit Rev Biochem Mol Biol (2010) 1.30
Thr-1989 phosphorylation is a marker of active ataxia telangiectasia-mutated and Rad3-related (ATR) kinase. J Biol Chem (2011) 1.16
Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex. J Biol Chem (2009) 1.14
RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response. Cell Res (2014) 1.10
Diffusion of human replication protein A along single-stranded DNA. J Mol Biol (2014) 1.10
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. J Virol (2010) 1.07
Physical interaction between replication protein A (RPA) and MRN: involvement of RPA2 phosphorylation and the N-terminus of RPA1. Biochemistry (2009) 1.07
Structural dynamics and single-stranded DNA binding activity of the three N-terminal domains of the large subunit of replication protein A from small angle X-ray scattering. Biochemistry (2010) 1.04
A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A. Anal Biochem (2011) 1.03
Small molecule inhibitor of the RPA70 N-terminal protein interaction domain discovered using in silico and in vitro methods. Bioorg Med Chem (2011) 1.01
SMARCAL1 and replication stress: an explanation for SIOD? Nucleus (2010) 1.01
Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis. Nucleic Acids Res (2009) 1.00
ATR maintains select progenitors during nervous system development. EMBO J (2012) 1.00
Physical interactions between Mcm10, DNA, and DNA polymerase alpha. J Biol Chem (2009) 0.99
A role for CDK9-cyclin K in maintaining genome integrity. Cell Cycle (2011) 0.98
Discovery of a potent stapled helix peptide that binds to the 70N domain of replication protein A. J Med Chem (2014) 0.97
Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A. ACS Med Chem Lett (2013) 0.95
RPA inhibition increases replication stress and suppresses tumor growth. Cancer Res (2014) 0.95
ETAA1 acts at stalled replication forks to maintain genome integrity. Nat Cell Biol (2016) 0.95
A small molecule directly inhibits the p53 transactivation domain from binding to replication protein A. Nucleic Acids Res (2012) 0.94
Activation of the ATR kinase by the RPA-binding protein ETAA1. Nat Cell Biol (2016) 0.94
RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks. Mol Cell (2015) 0.93
Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approach. J Med Chem (2013) 0.93
LIM Protein Ajuba Participates in the Repression of the ATR-Mediated DNA Damage Response. Front Genet (2013) 0.91
BID binds to replication protein A and stimulates ATR function following replicative stress. Mol Cell Biol (2011) 0.91
Human single-stranded DNA binding proteins are essential for maintaining genomic stability. BMC Mol Biol (2013) 0.91
Hyperphosphorylation of replication protein A in cisplatin-resistant and -sensitive head and neck squamous cell carcinoma cell lines. Head Neck (2010) 0.90
Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins. J Virol (2012) 0.89
Repair-specific functions of replication protein A. J Biol Chem (2011) 0.89
Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double strand breaks. PLoS One (2011) 0.88
Contributions of Rad9 to tumorigenesis. J Cell Biochem (2012) 0.88
Functional characterization of a cancer causing mutation in human replication protein A. Mol Cancer Res (2010) 0.88
Human DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress. J Biol Chem (2011) 0.87
In vitro analysis of the role of replication protein A (RPA) and RPA phosphorylation in ATR-mediated checkpoint signaling. J Biol Chem (2012) 0.87
Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo IIIα-RMI1-RMI2 protein complex. J Biol Chem (2013) 0.86
E3 ligase RFWD3 participates in replication checkpoint control. J Biol Chem (2011) 0.85
Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication protein A interaction motif of ATR interacting protein. Biochemistry (2013) 0.84
Essential functions of the 32 kDa subunit of yeast replication protein A. Nucleic Acids Res (2009) 0.84
Structural analysis of replication protein A recruitment of the DNA damage response protein SMARCAL1. Biochemistry (2014) 0.83
Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit. PLoS One (2013) 0.83
Analysis of mutations that dissociate G(2) and essential S phase functions of human ataxia telangiectasia-mutated and Rad3-related (ATR) protein kinase. J Biol Chem (2011) 0.82
Characteristics and concepts of dynamic hub proteins in DNA processing machinery from studies of RPA. Prog Biophys Mol Biol (2014) 0.81
Dynamic binding of replication protein a is required for DNA repair. Nucleic Acids Res (2016) 0.80
Bid protects the mouse hematopoietic system following hydroxyurea-induced replicative stress. Cell Death Differ (2012) 0.79
Cdk5 promotes DNA replication stress checkpoint activation through RPA-32 phosphorylation, and impacts on metastasis free survival in breast cancer patients. Cell Cycle (2015) 0.79
Intramolecular Binding of the Rad9 C Terminus in the Checkpoint Clamp Rad9-Hus1-Rad1 Is Closely Linked with Its DNA Binding. J Biol Chem (2015) 0.78
RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling. Nucleic Acids Res (2015) 0.78
Ewing Tumor-associated Antigen 1 Interacts with Replication Protein A to Promote Restart of Stalled Replication Forks. J Biol Chem (2016) 0.77
The N-terminus of RPA large subunit and its spatial position are important for the 5'->3' resection of DNA double-strand breaks. Nucleic Acids Res (2015) 0.77
Cdc45-induced loading of human RPA onto single-stranded DNA. Nucleic Acids Res (2017) 0.76
Molecular Evolution and Functional Diversification of Replication Protein A1 in Plants. Front Plant Sci (2016) 0.75
Managing Single-Stranded DNA during Replication Stress in Fission Yeast. Biomolecules (2015) 0.75
Insulin-like growth factor-1 receptor signaling is required for optimal ATR-CHK1 kinase signaling in UVB-irradiated human keratinocytes. J Biol Chem (2016) 0.75
PrimPol-Prime Time to Reprime. Genes (Basel) (2017) 0.75
Simian virus Large T antigen interacts with the N-terminal domain of the 70 kD subunit of Replication Protein A in the same mode as multiple DNA damage response factors. PLoS One (2015) 0.75
Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A. ChemMedChem (2016) 0.75
Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament. Nucleic Acids Res (2016) 0.75
Proteomics reveals a new DNA repair factor involved in DNA damage signaling. Mol Cell Oncol (2016) 0.75
Diphenylpyrazoles as replication protein a inhibitors. ACS Med Chem Lett (2014) 0.75
Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi. PLoS Negl Trop Dis (2016) 0.75
G9a coordinates with the RPA complex to promote DNA damage repair and cell survival. Proc Natl Acad Sci U S A (2017) 0.75
RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks. Mol Cell (2017) 0.75
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature (2005) 18.30
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science (2003) 18.29
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature (2005) 14.65
ATR: an essential regulator of genome integrity. Nat Rev Mol Cell Biol (2008) 11.86
The concept of synthetic lethality in the context of anticancer therapy. Nat Rev Cancer (2005) 8.99
Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell (1998) 8.31
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat Cell Biol (2005) 8.27
ATR and ATRIP: partners in checkpoint signaling. Science (2001) 7.58
TopBP1 activates the ATR-ATRIP complex. Cell (2006) 6.29
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint. Genes Dev (2005) 5.53
A dynamic model for replication protein A (RPA) function in DNA processing pathways. Nucleic Acids Res (2006) 4.49
Replication protein A-mediated recruitment and activation of Rad17 complexes. Proc Natl Acad Sci U S A (2003) 3.88
The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1. Genes Dev (2007) 3.58
The structural determinants of checkpoint activation. Genes Dev (2007) 3.53
Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA. PLoS Biol (2003) 3.29
ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation. Mol Biol Cell (2005) 3.08
Differential regulation of the cellular response to DNA double-strand breaks in G1. Mol Cell (2008) 3.02
An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication. Mol Cell (2003) 2.96
Replication protein A phosphorylation and the cellular response to DNA damage. DNA Repair (Amst) (2004) 2.92
TopBP1 activates ATR through ATRIP and a PIKK regulatory domain. Genes Dev (2008) 2.86
Activation of the DNA replication checkpoint through RNA synthesis by primase. Science (2000) 2.83
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro. Proc Natl Acad Sci U S A (2003) 2.80
Rapid activation of ATR by ionizing radiation requires ATM and Mre11. J Biol Chem (2006) 2.76
ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts. Mol Cell (2006) 2.73
The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR. J Biol Chem (2007) 2.68
Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A. Proc Natl Acad Sci U S A (2005) 2.59
Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex. DNA Repair (Amst) (2004) 2.55
Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. Genetics (1998) 2.37
DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair. Genes Dev (1998) 2.31
ATM regulates ATR chromatin loading in response to DNA double-strand breaks. J Exp Med (2006) 2.31
Function of a conserved checkpoint recruitment domain in ATRIP proteins. Mol Cell Biol (2007) 2.02
Replication protein A directs loading of the DNA damage checkpoint clamp to 5'-DNA junctions. J Biol Chem (2006) 2.00
Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex. Oncogene (2006) 1.93
DDB1 maintains genome integrity through regulation of Cdt1. Mol Cell Biol (2006) 1.84
Cellular functions of human RPA1. Multiple roles of domains in replication, repair, and checkpoints. J Biol Chem (2008) 1.67
Human replication protein A: global fold of the N-terminal RPA-70 domain reveals a basic cleft and flexible C-terminal linker. J Biomol NMR (1999) 1.66
Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality. Mol Cell Biol (2004) 1.63
Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cells. Oncogene (2005) 1.59
ATRIP associates with replication protein A-coated ssDNA through multiple interactions. Proc Natl Acad Sci U S A (2006) 1.55
DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts. J Cell Biol (2002) 1.54
Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences. Mol Cell Biol (2006) 1.51
Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors. Curr Opin Pharmacol (2005) 1.49
DNA replication defects, spontaneous DNA damage, and ATM-dependent checkpoint activation in replication protein A-deficient cells. J Biol Chem (2004) 1.47
Structural mechanisms of DNA replication, repair, and recombination. J Biol Chem (2004) 1.46
A role for the phosphorylation of hRad9 in checkpoint signaling. J Biol Chem (2003) 1.42
The Mre11 complex mediates the S-phase checkpoint through an interaction with replication protein A. Mol Cell Biol (2007) 1.38
5' --> 3' molecular polarity of human replication protein A (hRPA) binding to pseudo-origin DNA substrates. Biochemistry (2000) 1.31
Phosphorylation of Chk1 by ATM- and Rad3-related (ATR) in Xenopus egg extracts requires binding of ATRIP to ATR but not the stable DNA-binding or coiled-coil domains of ATRIP. J Biol Chem (2005) 1.30
Cdc18 enforces long-term maintenance of the S phase checkpoint by anchoring the Rad3-Rad26 complex to chromatin. Mol Cell (2007) 1.16
Different requirements for the association of ATR-ATRIP and 9-1-1 to the stalled replication forks. Gene (2006) 1.03
ATR: an essential regulator of genome integrity. Nat Rev Mol Cell Biol (2008) 11.86
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin. Genes Dev (2002) 4.58
Metal chelation and inhibition of bacterial growth in tissue abscesses. Science (2008) 4.55
ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation. Mol Biol Cell (2005) 3.08
TopBP1 activates ATR through ATRIP and a PIKK regulatory domain. Genes Dev (2008) 2.86
Rapid activation of ATR by ionizing radiation requires ATM and Mre11. J Biol Chem (2006) 2.76
Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control. Mol Cell (2008) 2.71
Calmodulin mutations associated with recurrent cardiac arrest in infants. Circulation (2013) 2.66
Nutrient metal sequestration by calprotectin inhibits bacterial superoxide defense, enhancing neutrophil killing of Staphylococcus aureus. Cell Host Microbe (2011) 2.66
Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut. Cell Host Microbe (2012) 2.66
The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks. Genes Dev (2009) 2.50
Analysis of protein dynamics at active, stalled, and collapsed replication forks. Genes Dev (2011) 2.47
ATR signalling: more than meeting at the fork. Biochem J (2011) 2.37
Structural insights into the U-box, a domain associated with multi-ubiquitination. Nat Struct Biol (2003) 2.26
Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases. Mol Cell (2012) 2.07
Function of a conserved checkpoint recruitment domain in ATRIP proteins. Mol Cell Biol (2007) 2.02
SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication. Genes Dev (2012) 1.85
DDB1 maintains genome integrity through regulation of Cdt1. Mol Cell Biol (2006) 1.84
S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway. J Leukoc Biol (2008) 1.82
Common mechanisms of PIKK regulation. DNA Repair (Amst) (2009) 1.73
Target selectivity in EF-hand calcium binding proteins. Biochim Biophys Acta (2004) 1.72
An iron-sulfur cluster in the C-terminal domain of the p58 subunit of human DNA primase. J Biol Chem (2007) 1.71
ATR phosphorylates SMARCAL1 to prevent replication fork collapse. Genes Dev (2013) 1.70
The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in rheumatoid arthritis. Arthritis Res Ther (2006) 1.67
Physical interaction between replication protein A and Rad51 promotes exchange on single-stranded DNA. J Biol Chem (2004) 1.65
Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens. Proc Natl Acad Sci U S A (2013) 1.64
Independent and coordinated functions of replication protein A tandem high affinity single-stranded DNA binding domains. J Biol Chem (2003) 1.59
An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability. Nat Struct Mol Biol (2004) 1.59
Dpb11 activates the Mec1-Ddc2 complex. Proc Natl Acad Sci U S A (2008) 1.58
Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain. J Biol Chem (2004) 1.52
The extracellular region of the receptor for advanced glycation end products is composed of two independent structural units. Biochemistry (2007) 1.51
ATRIP oligomerization is required for ATR-dependent checkpoint signaling. J Biol Chem (2005) 1.51
Structural basis for ligand recognition and activation of RAGE. Structure (2010) 1.50
Insights into hRPA32 C-terminal domain--mediated assembly of the simian virus 40 replisome. Nat Struct Mol Biol (2005) 1.50
DNA damage response: three levels of DNA repair regulation. Cold Spring Harb Perspect Biol (2013) 1.48
Identification of an Acinetobacter baumannii zinc acquisition system that facilitates resistance to calprotectin-mediated zinc sequestration. PLoS Pathog (2012) 1.47
Structural mechanisms of DNA replication, repair, and recombination. J Biol Chem (2004) 1.46
Calcium-modulated S100 protein-phospholipid interactions. An NMR study of calbindin D9k and DPC. Biochemistry (2005) 1.46
Monitoring the spatiotemporal dynamics of proteins at replication forks and in assembled chromatin using isolation of proteins on nascent DNA. Nat Protoc (2012) 1.45
Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry. J Biol Chem (2013) 1.43
Structural and functional analysis of essential pre-mRNA splicing factor Prp19p. Mol Cell Biol (2005) 1.42
S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3. Cell Res (2009) 1.42
Substrate-selective repair and restart of replication forks by DNA translocases. Cell Rep (2013) 1.39
Structure-function analysis of inositol hexakisphosphate-induced autoprocessing in Clostridium difficile toxin A. J Biol Chem (2009) 1.39
The Prp19 U-box crystal structure suggests a common dimeric architecture for a class of oligomeric E3 ubiquitin ligases. Biochemistry (2006) 1.38
Functional genomic screens identify CINP as a genome maintenance protein. Proc Natl Acad Sci U S A (2009) 1.38
Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switch. Proc Natl Acad Sci U S A (2006) 1.36
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response. EMBO Rep (2010) 1.36
The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements. Mol Endocrinol (2005) 1.34
Solution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5. J Mol Biol (2010) 1.32
Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5. J Biol Chem (2008) 1.32
Structure of the Ca2+/S100B/NDR kinase peptide complex: insights into S100 target specificity and activation of the kinase. Biochemistry (2003) 1.30
Novel calmodulin mutations associated with congenital arrhythmia susceptibility. Circ Cardiovasc Genet (2014) 1.27
Cyclin-dependent kinase 2 dependent phosphorylation of ATRIP regulates the G2-M checkpoint response to DNA damage. Cancer Res (2007) 1.27
Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants. Circ Res (2014) 1.27
Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair. J Biol Chem (2010) 1.26
Structural mechanism of RPA loading on DNA during activation of a simple pre-replication complex. EMBO J (2006) 1.25
S100A8/A9: a Janus-faced molecule in cancer therapy and tumorgenesis. Eur J Pharmacol (2009) 1.24
Distinct functions of S. pombe Rec12 (Spo11) protein and Rec12-dependent crossover recombination (chiasmata) in meiosis I; and a requirement for Rec12 in meiosis II. Cell Chromosome (2002) 1.23
Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin. J Biol Chem (2009) 1.22
Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase. Proc Natl Acad Sci U S A (2010) 1.21
Checkpoint kinase ATR promotes nucleotide excision repair of UV-induced DNA damage via physical interaction with xeroderma pigmentosum group A. J Biol Chem (2009) 1.19
S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2. Biochim Biophys Acta (2007) 1.19
Direct ubiquitination of beta-catenin by Siah-1 and regulation by the exchange factor TBL1. J Biol Chem (2010) 1.18
MntABC and MntH contribute to systemic Staphylococcus aureus infection by competing with calprotectin for nutrient manganese. Infect Immun (2013) 1.17
The EF-hand domain: a globally cooperative structural unit. Protein Sci (2002) 1.17
Thr-1989 phosphorylation is a marker of active ataxia telangiectasia-mutated and Rad3-related (ATR) kinase. J Biol Chem (2011) 1.16
Structural basis for DNA binding by replication initiator Mcm10. Structure (2008) 1.14
Activation of ATR and related PIKKs. Cell Cycle (2008) 1.12
A new structural framework for integrating replication protein A into DNA processing machinery. Nucleic Acids Res (2013) 1.12
In support of the BMRB. Nat Struct Mol Biol (2012) 1.09
Unique features in the C-terminal domain provide caltractin with target specificity. J Mol Biol (2003) 1.09
NMR analysis of the architecture and functional remodeling of a modular multidomain protein, RPA. J Am Chem Soc (2009) 1.08
Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling. J Exp Med (2012) 1.07
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. J Virol (2010) 1.07
Stable RAGE-heparan sulfate complexes are essential for signal transduction. ACS Chem Biol (2013) 1.07
Alpha4 is a ubiquitin-binding protein that regulates protein serine/threonine phosphatase 2A ubiquitination. Biochemistry (2010) 1.06
Biochemical and structural domain analysis of xeroderma pigmentosum complementation group C protein. Biochemistry (2006) 1.05
Structure of the S100A6 complex with a fragment from the C-terminal domain of Siah-1 interacting protein: a novel mode for S100 protein target recognition. Biochemistry (2008) 1.04
Structural dynamics and single-stranded DNA binding activity of the three N-terminal domains of the large subunit of replication protein A from small angle X-ray scattering. Biochemistry (2010) 1.04
Implication of extracellular zinc exclusion by recombinant human calprotectin (MRP8 and MRP14) from target cells in its apoptosis-inducing activity. Mediators Inflamm (2002) 1.03
A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A. Anal Biochem (2011) 1.03
Engineering and design of ligand-induced conformational change in proteins. Curr Opin Struct Biol (2002) 1.02
HDAC3 is essential for DNA replication in hematopoietic progenitor cells. J Clin Invest (2013) 1.02
Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition. J Mol Biol (2005) 1.01
Structural and functional characterization of the monomeric U-box domain from E4B. Biochemistry (2010) 1.01
SMARCAL1 and replication stress: an explanation for SIOD? Nucleus (2010) 1.01
Calmodulin interacts with the V2 vasopressin receptor: elimination of binding to the C terminus also eliminates arginine vasopressin-stimulated elevation of intracellular calcium. J Biol Chem (2004) 1.00
Histone acetyl transferase 1 is essential for mammalian development, genome stability, and the processing of newly synthesized histones H3 and H4. PLoS Genet (2013) 0.99
Physical interactions between Mcm10, DNA, and DNA polymerase alpha. J Biol Chem (2009) 0.99
A role for CDK9-cyclin K in maintaining genome integrity. Cell Cycle (2011) 0.98