Published in Nat Genet on July 13, 2009
Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98
Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79
Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. Lancet Neurol (2012) 3.93
Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71
Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2014) 3.48
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet (2012) 3.40
Several common variants modulate heart rate, PR interval and QRS duration. Nat Genet (2010) 3.34
Cohort profile: the Tromso Study. Int J Epidemiol (2011) 3.29
Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association. Circulation (2017) 2.76
Atrial fibrillation: current knowledge and future directions in epidemiology and genomics. Circulation (2011) 2.36
Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis. PLoS Genet (2012) 1.97
Independent susceptibility markers for atrial fibrillation on chromosome 4q25. Circulation (2010) 1.90
Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. J Am Coll Cardiol (2014) 1.86
Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification. Proc Natl Acad Sci U S A (2010) 1.84
Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation. J Am Coll Cardiol (2012) 1.84
Association between familial atrial fibrillation and risk of new-onset atrial fibrillation. JAMA (2010) 1.75
Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations. Cerebrovasc Dis (2013) 1.47
Genome-wide association studies in cardiac electrophysiology: recent discoveries and implications for clinical practice. Heart Rhythm (2010) 1.45
Genetic polymorphisms confer risk of atrial fibrillation in patients with heart failure: a population-based study. Eur J Heart Fail (2012) 1.43
Ischemic stroke is associated with the ABO locus: the EuroCLOT study. Ann Neurol (2013) 1.30
Genome-wide association studies of atrial fibrillation: past, present, and future. Cardiovasc Res (2011) 1.27
Symptomatic response to antiarrhythmic drug therapy is modulated by a common single nucleotide polymorphism in atrial fibrillation. J Am Coll Cardiol (2012) 1.27
Common atrial fibrillation risk alleles at 4q25 predict recurrence after catheter-based atrial fibrillation ablation. Heart Rhythm (2012) 1.23
Lone atrial fibrillation: does it exist? J Am Coll Cardiol (2014) 1.21
Genetic susceptibility to ischemic stroke. Nat Rev Neurol (2011) 1.12
Genetic mechanisms of atrial fibrillation: impact on response to treatment. Nat Rev Cardiol (2013) 1.11
Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. Circulation (2014) 1.11
Significant association of SNP rs2106261 in the ZFHX3 gene with atrial fibrillation in a Chinese Han GeneID population. Hum Genet (2010) 1.09
Twelve-single nucleotide polymorphism genetic risk score identifies individuals at increased risk for future atrial fibrillation and stroke. Stroke (2014) 1.08
Pitx2, an atrial fibrillation predisposition gene, directly regulates ion transport and intercalated disc genes. Circ Cardiovasc Genet (2014) 1.07
Atrial fibrillation in congestive heart failure. Heart Fail Clin (2010) 1.07
Large-scale candidate gene analysis in whites and African Americans identifies IL6R polymorphism in relation to atrial fibrillation: the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) project. Circ Cardiovasc Genet (2011) 1.06
Genetics of atrial fibrillation: implications for future research directions and personalized medicine. Circ Arrhythm Electrophysiol (2010) 1.01
Phenome-wide association studies (PheWASs) for functional variants. Eur J Hum Genet (2014) 0.99
The pathology and treatment of cardiac arrhythmias: focus on atrial fibrillation. Vasc Health Risk Manag (2011) 0.99
Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies. Stroke (2014) 0.99
Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. Lancet Neurol (2015) 0.98
Genetics of atrial fibrillation: from families to genomes. J Hum Genet (2015) 0.96
A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach. PLoS Genet (2014) 0.96
Emerging directions in the genetics of atrial fibrillation. Circ Res (2014) 0.96
Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm. Dis Model Mech (2012) 0.93
Unravelling the human genome-phenome relationship using phenome-wide association studies. Nat Rev Genet (2016) 0.92
Characterization of genome-wide association-identified variants for atrial fibrillation in African Americans. PLoS One (2012) 0.92
Common variants for atrial fibrillation: results from genome-wide association studies. Hum Genet (2011) 0.92
Association between variants on chromosome 4q25, 16q22 and 1q21 and atrial fibrillation in the Polish population. PLoS One (2011) 0.92
Stroke genetics: a review and update. J Stroke (2014) 0.91
Differential impact of race and risk factors on incidence of atrial fibrillation. Am Heart J (2011) 0.91
Novel association of polymorphic genetic variants with predictors of outcome of catheter ablation in atrial fibrillation: new directions from a prospective study (DECAF). J Interv Card Electrophysiol (2016) 0.90
Stroke genetics: prospects for personalized medicine. BMC Med (2012) 0.90
Low-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration. Neurology (2016) 0.90
Heterozygous deletion of Atbf1 by the Cre-loxP system in mice causes preweaning mortality. Genesis (2012) 0.89
Genome-wide association studies of late-onset cardiovascular disease. J Mol Cell Cardiol (2015) 0.89
Deletion of atbf1/zfhx3 in mouse prostate causes neoplastic lesions, likely by attenuation of membrane and secretory proteins and multiple signaling pathways. Neoplasia (2014) 0.89
Molecular Basis of Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS Gene-Gene Interaction Involved in Atrial Fibrillation. PLoS Genet (2015) 0.88
Genetics of ischemic stroke in young adults. Circ Cardiovasc Genet (2014) 0.87
Association of genetic variants with coronary artery disease and ischemic stroke in a longitudinal population-based genetic epidemiological study. Biomed Rep (2015) 0.87
Genomic risk profiling of ischemic stroke: results of an international genome-wide association meta-analysis. PLoS One (2011) 0.87
Unravelling the genetics of ischaemic stroke. PLoS Med (2010) 0.87
Gene-guided therapy for catheter-ablation of atrial fibrillation: are we there yet? J Interv Card Electrophysiol (2015) 0.87
The "missing" link in atrial fibrillation heritability. J Electrocardiol (2011) 0.87
A genetic risk score for hypertension associates with the risk of ischemic stroke in a Swedish case-control study. Eur J Hum Genet (2014) 0.86
Genetic predisposition to coronary heart disease and stroke using an additive genetic risk score: a population-based study in Greece. Atherosclerosis (2012) 0.86
Korean Atrial Fibrillation (AF) Network: Genetic Variants for AF Do Not Predict Ablation Success. J Am Heart Assoc (2015) 0.85
Common variation in atrial fibrillation: navigating the path from genetic association to mechanism. Cardiovasc Res (2016) 0.85
Significant Association Between CAV1 Variant rs3807989 on 7p31 and Atrial Fibrillation in a Chinese Han Population. J Am Heart Assoc (2015) 0.85
High familial risk of atrial fibrillation/atrial flutter in multiplex families: a nationwide family study in Sweden. J Am Heart Assoc (2012) 0.85
New information on the genetics of stroke. Curr Neurol Neurosci Rep (2011) 0.85
A contemporary review on the genetic basis of atrial fibrillation. Methodist Debakey Cardiovasc J (2014) 0.84
Candidate gene approach to identifying rare genetic variants associated with lone atrial fibrillation. Heart Rhythm (2013) 0.84
New advances in the genetic basis of atrial fibrillation. J Cardiovasc Electrophysiol (2012) 0.84
Evaluation of non-synonymous NPPA single nucleotide polymorphisms in atrial fibrillation. Europace (2010) 0.84
Targeted deep sequencing reveals no definitive evidence for somatic mosaicism in atrial fibrillation. Circ Cardiovasc Genet (2014) 0.84
Characterization of nuclear localization and SUMOylation of the ATBF1 transcription factor in epithelial cells. PLoS One (2014) 0.83
Challenges in the classification of atrial fibrillation. Nat Rev Cardiol (2010) 0.83
Genetic Risk Prediction of Atrial Fibrillation. Circulation (2016) 0.83
The role of transcription factors in atrial fibrillation. J Thorac Dis (2015) 0.82
Long-range regulatory interactions at the 4q25 atrial fibrillation risk locus involve PITX2c and ENPEP. BMC Biol (2015) 0.82
Stroke genomics in people of African ancestry: charting new paths. Cardiovasc J Afr (2015) 0.81
The 4q25, 1q21, and 16q22 polymorphisms and recurrence of atrial fibrillation after pulmonary vein isolation. Arch Med Sci (2016) 0.81
Blood biomarkers in cardioembolic stroke. Curr Cardiol Rev (2010) 0.81
Genetic polymorphisms for estimating risk of atrial fibrillation: a literature-based meta-analysis. J Intern Med (2012) 0.81
Genetic mutations in African patients with atrial fibrillation: Rationale and design of the Study of Genetics of Atrial Fibrillation in an African Population (SIGNAL). Am Heart J (2015) 0.81
Outcomes Associated With Familial Versus Nonfamilial Atrial Fibrillation: A Matched Nationwide Cohort Study. J Am Heart Assoc (2016) 0.81
Genomics of Atrial Fibrillation. Curr Cardiol Rep (2016) 0.80
Transgenic insights linking pitx2 and atrial arrhythmias. Front Physiol (2012) 0.80
Genome-wide association studies in neurology. Ann Transl Med (2014) 0.80
Exploring the interaction between SNP genotype and postmenopausal hormone therapy effects on stroke risk. Genome Med (2012) 0.79
Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2. Stroke (2016) 0.79
TheTGFB1 functional polymorphism rs1800469 and susceptibility to atrial fibrillation in two Chinese Han populations. PLoS One (2013) 0.79
Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals. JAMA Cardiol (2016) 0.79
Novel Nucleotide Variations, Haplotypes Structure and Associations with Growth Related Traits of Goat AT Motif-Binding Factor (ATBF1) Gene. Asian-Australas J Anim Sci (2015) 0.78
Severity of obstructive sleep apnea influences the effect of genotype on response to anti-arrhythmic drug therapy for atrial fibrillation. J Clin Sleep Med (2014) 0.78
Telomere length and the risk of atrial fibrillation: insights into the role of biological versus chronological aging. Circ Arrhythm Electrophysiol (2014) 0.78
Cardiovascular disease gets personal. Nature (2009) 0.78
The reduction of vascular disease risk mutations contributes to longevity in the Chinese population. Meta Gene (2014) 0.78
Chromosome 16q22 variants in a region associated with cardiovascular phenotypes correlate with ZFHX3 expression in a transcript-specific manner. BMC Genet (2014) 0.78
Genetic loci associated with atrial fibrillation: relation to left atrial structure in the Framingham Heart Study. J Am Heart Assoc (2014) 0.78
Lifetime risk for development of atrial fibrillation: the Framingham Heart Study. Circulation (2004) 8.80
Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature (2007) 8.03
Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke. Ann Neurol (2008) 3.75
Antithrombotic treatment in atrial fibrillation. Heart (2005) 2.00
Positive and negative regulation of myogenic differentiation of C2C12 cells by isoforms of the multiple homeodomain zinc finger transcription factor ATBF1. J Biol Chem (2001) 1.95
A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers. Mol Cell Biol (1991) 1.89
Finding the missing heritability of complex diseases. Nature (2009) 67.95
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
A high-resolution recombination map of the human genome. Nat Genet (2002) 28.66
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Genomewide association analysis of coronary artery disease. N Engl J Med (2007) 24.38
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Genetics of gene expression and its effect on disease. Nature (2008) 21.35
Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Association between microdeletion and microduplication at 16p11.2 and autism. N Engl J Med (2008) 19.71
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet (2007) 19.18
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet (2006) 19.03
A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science (2007) 18.96
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature (2008) 16.10
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet (2009) 15.15
A common genetic variant is associated with adult and childhood obesity. Science (2006) 14.95
Missing heritability and strategies for finding the underlying causes of complex disease. Nat Rev Genet (2010) 14.81
A common inversion under selection in Europeans. Nat Genet (2005) 13.66
A common variant associated with prostate cancer in European and African populations. Nat Genet (2006) 13.47
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet (2007) 13.28
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25