Published in Proc Natl Acad Sci U S A on August 10, 2009
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Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice. Proc Natl Acad Sci U S A (2004) 2.00
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A structural basis for enhancement of long-term associative memory in single dendritic spines regulated by PKC. Proc Natl Acad Sci U S A (2007) 1.55
Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory. Proc Natl Acad Sci U S A (2004) 1.47
Neuronal ELAV proteins enhance mRNA stability by a PKCalpha-dependent pathway. Proc Natl Acad Sci U S A (2005) 1.45
Poststroke neuronal rescue and synaptogenesis mediated in vivo by protein kinase C in adult brains. Proc Natl Acad Sci U S A (2008) 1.42
Memory-specific temporal profiles of gene expression in the hippocampus. Proc Natl Acad Sci U S A (2002) 1.38
PKC ε activation prevents synaptic loss, Aβ elevation, and cognitive deficits in Alzheimer's disease transgenic mice. J Neurosci (2011) 1.32
Insulin, PKC signaling pathways and synaptic remodeling during memory storage and neuronal repair. Eur J Pharmacol (2008) 1.18
A cellular model of Alzheimer's disease therapeutic efficacy: PKC activation reverses Abeta-induced biomarker abnormality on cultured fibroblasts. Neurobiol Dis (2009) 1.16
Dual effects of bryostatin-1 on spatial memory and depression. Eur J Pharmacol (2005) 1.16
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Insulin receptor signaling in long-term memory consolidation following spatial learning. Learn Mem (2005) 1.08
Bryostatin improves survival and reduces ischemic brain injury in aged rats after acute ischemic stroke. Stroke (2013) 1.05
Correlated calcium uptake and release by mitochondria and endoplasmic reticulum of CA3 hippocampal dendrites after afferent synaptic stimulation. J Neurosci (2002) 1.02
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Carbonic anhydrase gating of attention: memory therapy and enhancement. Trends Pharmacol Sci (2002) 0.97
Gene expression profiles in a transgenic animal model of fragile X syndrome. Neurobiol Dis (2002) 0.96
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Reduction of beta-amyloid levels by novel protein kinase C(epsilon) activators. J Biol Chem (2009) 0.95
Pharmacological protection of synaptic function, spatial learning, and memory from transient hypoxia in rats. J Pharmacol Exp Ther (2002) 0.93
MAP kinase signaling cascade dysfunction specific to Alzheimer's disease in fibroblasts. Neurobiol Dis (2002) 0.92
An internally controlled peripheral biomarker for Alzheimer's disease: Erk1 and Erk2 responses to the inflammatory signal bradykinin. Proc Natl Acad Sci U S A (2006) 0.92
Secretion of Annexin II via activation of insulin receptor and insulin-like growth factor receptor. J Biol Chem (2002) 0.92
Protection against beta-amyloid-induced apoptosis by peptides interacting with beta-amyloid. J Biol Chem (2007) 0.89
Hippocampal protein-protein interactions in spatial memory. Hippocampus (2004) 0.88
Impairment of phosphatase 2A contributes to the prolonged MAP kinase phosphorylation in Alzheimer's disease fibroblasts. Neurobiol Dis (2003) 0.88
Apolipoprotein E3 (ApoE3) but not ApoE4 protects against synaptic loss through increased expression of protein kinase C epsilon. J Biol Chem (2012) 0.88
Impairment of hippocampal CA1 heterosynaptic transformation and spatial memory by beta-amyloid(25-35). J Neurophysiol (2002) 0.87
Time windows for effects of protein synthesis inhibitors on Pavlovian conditioning in Hermissenda: behavioral aspects. Neurobiol Learn Mem (2003) 0.87
Calcium-regulated GTPase activity in the calcium-binding protein calexcitin. Comp Biochem Physiol B Biochem Mol Biol (2003) 0.87
Quantification and distribution of beta-secretase alternative splice variants in the rat and human brain. Brain Res Mol Brain Res (2003) 0.87
PKC activator therapeutic for mild traumatic brain injury in mice. Neurobiol Dis (2010) 0.87
c-Src protein tyrosine kinase activity is required for muscarinic receptor-mediated DNA synthesis and neurogenesis via ERK1/2 and c-AMP-responsive element-binding protein signaling in neural precursor cells. J Neurosci Res (2003) 0.86
Differential gender-related vulnerability to depression induction and converging antidepressant responses in rats. J Pharmacol Exp Ther (2005) 0.86
PKC activation during training restores mushroom spine synapses and memory in the aged rat. Neurobiol Dis (2013) 0.86
Early diagnostic accuracy and pathophysiologic relevance of an autopsy-confirmed Alzheimer's disease peripheral biomarker. Neurobiol Aging (2008) 0.86
Open space swimming test to index antidepressant activity. J Neurosci Methods (2003) 0.85
Synergistic effects of chronic bryostatin-1 and alpha-tocopherol on spatial learning and memory in rats. Eur J Pharmacol (2008) 0.85
Protein kinase C stimulates HuD-mediated mRNA stability and protein expression of neurotrophic factors and enhances dendritic maturation of hippocampal neurons in culture. Hippocampus (2012) 0.85
Links between Alzheimer's disease and diabetes. Drugs Today (Barc) (2006) 0.85
Activation of protein kinase C isozymes for the treatment of dementias. Adv Pharmacol (2012) 0.84
Gene expression of alpha-endosulfine in the rat brain: correlative changes with aging, learning and stress. J Neurochem (2003) 0.84
Regional rat brain distribution of heme oxygenase-1 and manganese superoxide dismutase mRNA: relevance of redox homeostasis in the aging processes. Exp Biol Med (Maywood) (2003) 0.83
Protein kinase C activators as synaptogenic and memory therapeutics. Arch Pharm (Weinheim) (2009) 0.83
Bryostatin-1 restores hippocampal synapses and spatial learning and memory in adult fragile x mice. J Pharmacol Exp Ther (2014) 0.82
Alzheimer's Disease Cerebrospinal Fluid and Neuroimaging Biomarkers: Diagnostic Accuracy and Relationship to Drug Efficacy. J Alzheimers Dis (2015) 0.82
Analysis of long-term cognitive-enhancing effects of bryostatin-1 on the rabbit (Oryctolagus cuniculus) nictitating membrane response. Behav Pharmacol (2008) 0.81
Emerging targets for the pharmacology of learning and memory. Pharmacol Res (2004) 0.81
Behavioral effects of dietary cholesterol in rats tested in experimental models of mild stress and cognition tasks. Eur Neuropsychopharmacol (2008) 0.81
Age-dependent enhancement of inhibitory synaptic transmission in CA1 pyramidal neurons via GluR5 kainate receptors. Hippocampus (2009) 0.81
Translocation of protein kinase C-betaII in astrocytes requires organized actin cytoskeleton and is not accompanied by synchronous RACK1 relocation. Glia (2004) 0.80
Cerebral ischemia-induced difference in sensitivity to depression and potential therapeutics in rats. Behav Pharmacol (2013) 0.79
Programs of gene expression during the laying down of memory formation as revealed by DNA microarrays. Neurochem Res (2002) 0.79
Protein kinase C pharmacology: perspectives on therapeutic potentials as antidementic and cognitive agents. Recent Pat CNS Drug Discov (2006) 0.78
Cerebral hypoperfusion and amyloid-induced synergistic impairment of hippocampal CA1 synaptic efficacy and spatial memory in young adult rats. J Alzheimers Dis (2004) 0.78
Two different biological configurations for long-term memory. Neurobiol Learn Mem (2004) 0.78
Links between Alzheimer's disease and diabetes. Timely Top Med Cardiovasc Dis (2006) 0.77
Gene expression profiles of apoptotic neurons. Genomics (2004) 0.77
Isolation of protein subpopulations undergoing protein-protein interactions. Mol Cell Proteomics (2002) 0.76
Spatiotemporal complexity of fibroblast networks screens for Alzheimer's disease. J Alzheimers Dis (2013) 0.76
Protein kinase C isozymes: memory therapeutic potential. Curr Drug Targets CNS Neurol Disord (2005) 0.76
Effects of 4-methylcatechol on spatial memory and depression. Neuroreport (2008) 0.76
Depressed or demented: common CNS drug targets?! Curr Drug Targets CNS Neurol Disord (2002) 0.75
Effects of age on susceptibility to the induction of depressive behavior and imipramine in rats. Behav Pharmacol (2008) 0.75
Memory Enhancement by Bryostatin in Hermissenda. Biol Bull (2004) 0.75
Stress: perspectives on its impact on cognition and pharmacological treatment. Behav Pharmacol (2014) 0.75