Published in Semin Reprod Med on August 26, 2009
Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease. Int J Epidemiol (2012) 2.12
The epigenetics of autoimmunity. Cell Mol Immunol (2011) 1.47
Epigenetic plasticity: a central regulator of epithelial-to-mesenchymal transition in cancer. Oncotarget (2014) 1.19
DNA sequence polymorphisms in a panel of eight candidate bovine imprinted genes and their association with performance traits in Irish Holstein-Friesian cattle. BMC Genet (2010) 1.14
Environmental and epigenetic effects upon preimplantation embryo metabolism and development. Trends Endocrinol Metab (2011) 1.00
Epigenetics and autoimmune diseases. Autoimmune Dis (2012) 0.97
Histone deacetylases (HDACs) in XPC gene silencing and bladder cancer. J Hematol Oncol (2011) 0.94
What do you mean, "epigenetic"? Genetics (2015) 0.93
Histone code, human growth and cancer. Oncotarget (2012) 0.82
5-Hydroxymethylcytosine: A new player in brain disorders? Exp Neurol (2014) 0.82
Cytosine modifications in neurodevelopment and diseases. Cell Mol Life Sci (2013) 0.81
Genetic and Environmental Interplay in Adolescent Substance Use Disorders. Curr Addict Rep (2015) 0.81
Epigenetics of Alzheimer's disease and frontotemporal dementia. Neurotherapeutics (2013) 0.80
Epigenetic Inheritance and Its Role in Evolutionary Biology: Re-Evaluation and New Perspectives. Biology (Basel) (2016) 0.80
Genetic associations with diminished ovarian reserve: a systematic review of the literature. J Assist Reprod Genet (2014) 0.78
Epigenetic Mechanisms of Serotonin Signaling. ACS Chem Neurosci (2015) 0.77
Genomics, microRNA, epigenetics, and proteomics for future diagnosis, treatment and monitoring response in upper GI cancers. Clin Transl Med (2016) 0.77
The epigenome: the next substrate for engineering. Genome Biol (2016) 0.77
Identification and characterization of PKF118-310 as a KDM4A inhibitor. Epigenetics (2016) 0.77
Physiologic Course of Female Reproductive Function: A Molecular Look into the Prologue of Life. J Pregnancy (2015) 0.76
Natural Killer Cells-An Epigenetic Perspective of Development and Regulation. Int J Mol Sci (2016) 0.76
Epigenetic reprogramming in Mist1(-/-) mice predicts the molecular response to cerulein-induced pancreatitis. PLoS One (2014) 0.76
Evolution and conservation of JmjC domain proteins in the green lineage. Mol Genet Genomics (2015) 0.76
Epigenetic regulations on skin wound healing: implications from current researches. Ann Transl Med (2015) 0.75
Taking a chance on epigenetics. Front Genet (2014) 0.75
Potential role of epigenetic mechanisms in regulation of trophoblast differentiation, migration, and invasion in the human placenta. Cell Adh Migr (2016) 0.75
Is ICSI Risky? Obstet Gynecol Int (2013) 0.75
Epigenetic modulation in the treatment of atherosclerotic disease. Front Genet (2014) 0.75
Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins. Int J Mol Sci (2017) 0.75
Intersystem Implications of the Developmental Origins of Health and Disease: Advancing Health Promotion in the 21st Century. Healthcare (Basel) (2016) 0.75
Glutamate carboxypeptidase II and folate deficiencies result in reciprocal protection against cognitive and social deficits in mice: implications for neurodevelopmental disorders. Dev Neurobiol (2012) 0.75
Identification of SET Domain-Containing Proteins in Gossypium raimondii and Their Response to High Temperature Stress. Sci Rep (2016) 0.75
Emerging Role of Nutri-Epigenetics in Inflammation and Cancer. Oncol Nurs Forum (2016) 0.75
Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology. Biochim Biophys Acta (2017) 0.75
Chromatin modifications and their function. Cell (2007) 55.98
The language of covalent histone modifications. Nature (2000) 44.92
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell (1999) 25.75
Gene action in the X-chromosome of the mouse (Mus musculus L.). Nature (1961) 23.98
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature (1998) 18.36
Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci (2006) 13.32
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet (1998) 13.27
Chromatin structure: a repeating unit of histones and DNA. Science (1974) 13.18
Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. Cell (2004) 10.16
ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS. Proc Natl Acad Sci U S A (1964) 9.91
Epigenetic inheritance at the agouti locus in the mouse. Nat Genet (1999) 9.14
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc Natl Acad Sci U S A (2000) 8.12
Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol Cell Biol (1998) 7.61
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat Genet (1998) 7.52
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature (2004) 7.42
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell (1992) 7.11
Parental imprinting of the mouse insulin-like growth factor II gene. Cell (1991) 7.11
Noncoding RNAs and gene silencing. Cell (2007) 5.99
Histone lysine methylation: a signature for chromatin function. Trends Genet (2003) 5.55
Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J Mol Biol (1988) 5.24
Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse. Genesis (2003) 5.19
X chromosome dosage compensation: how mammals keep the balance. Annu Rev Genet (2008) 5.18
The role of X-chromosome inactivation during spermatogenesis (Drosophila-allocycly-chromosome evolution-male sterility-dosage compensation). Proc Natl Acad Sci U S A (1972) 5.14
Parental imprinting of the mouse H19 gene. Nature (1991) 5.13
Histone H2A variants H2AX and H2AZ. Curr Opin Genet Dev (2002) 5.11
RNA synthesis and histone acetylation during the course of gene activation in lymphocytes. Proc Natl Acad Sci U S A (1966) 5.06
Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nat Struct Mol Biol (2006) 4.93
DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein. Cell (1991) 4.90
Completion of mouse embryogenesis requires both the maternal and paternal genomes. Cell (1984) 4.44
Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis. Nature (1984) 4.22
Dosage compensation in mammals: fine-tuning the expression of the X chromosome. Genes Dev (2006) 4.17
Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter. Genes Dev (1988) 4.02
Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cells. Proc Natl Acad Sci U S A (2007) 3.99
Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse. Nature (1975) 3.75
PGC7/Stella protects against DNA demethylation in early embryogenesis. Nat Cell Biol (2006) 3.54
The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus. Nature (1991) 3.48
Differential effects of culture on imprinted H19 expression in the preimplantation mouse embryo. Biol Reprod (2000) 3.33
The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells. RNA (2005) 3.14
The majority of methylated deoxycytidines in human DNA are not in the CpG dinucleotide. Biochem Biophys Res Commun (1987) 3.08
What good is genomic imprinting: the function of parent-specific gene expression. Nat Rev Genet (2003) 2.82
Histone variants, nucleosome assembly and epigenetic inheritance. Trends Genet (2004) 2.78
Inheritance of a pre-inactivated paternal X chromosome in early mouse embryos. Nature (2003) 2.76
Histone H3 variants and their potential role in indexing mammalian genomes: the "H3 barcode hypothesis". Proc Natl Acad Sci U S A (2006) 2.68
Imprinted X inactivation maintained by a mouse Polycomb group gene. Nat Genet (2001) 2.63
Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice. Nature (2005) 2.46
Histone acetylation reduces nucleosome core particle linking number change. Cell (1989) 2.41
The H19 methylation imprint is erased and re-established differentially on the parental alleles during male germ cell development. Hum Mol Genet (2000) 2.33
The action of pancreatic deoxyribonuclease. II. Isomeric dinucleotides. J Biol Chem (1955) 2.26
Gene-specific timing and epigenetic memory in oocyte imprinting. Hum Mol Genet (2004) 2.25
Studies of the DNA binding properties of histone H4 amino terminus. Thermal denaturation studies reveal that acetylation markedly reduces the binding constant of the H4 "tail" to DNA. J Biol Chem (1993) 2.16
Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization. J Biol Chem (2005) 2.10
Histone modifying enzymes: structures, mechanisms, and specificities. Biochim Biophys Acta (2008) 2.07
Culture of preimplantation mouse embryos affects fetal development and the expression of imprinted genes. Biol Reprod (2001) 1.97
Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer. Int J Cancer (2009) 1.94
Evidence that random and imprinted Xist expression is controlled by preemptive methylation. Cell (1994) 1.88
Genes, genetics, and epigenetics: a correspondence. Science (2001) 1.85
Timing of establishment of paternal methylation imprints in the mouse. Genomics (2004) 1.84
Oocyte growth-dependent progression of maternal imprinting in mice. Genes Cells (2006) 1.84
X inactivation in the mouse embryo deficient for Dnmt1: distinct effect of hypomethylation on imprinted and random X inactivation. Dev Biol (2000) 1.80
Active gene sequences are undermethylated. Proc Natl Acad Sci U S A (1981) 1.79
Asymmetry in histone H3 variants and lysine methylation between paternal and maternal chromatin of the early mouse zygote. Mech Dev (2005) 1.79
A FRACTIONATION OF THE HISTONES OF GROUP F2A FROM CALF THYMUS. Biochem J (1965) 1.78
Phosphoglycerate kinase polymorphism in kangaroos provides further evidence for paternal X inactivation. Nat New Biol (1971) 1.78
Molecular links between X-inactivation and autosomal imprinting: X-inactivation as a driving force for the evolution of imprinting? Curr Biol (2003) 1.66
Programming of gene expression by Polycomb group proteins. Trends Cell Biol (2008) 1.66
Mechanism of human methyl-directed DNA methyltransferase and the fidelity of cytosine methylation. Proc Natl Acad Sci U S A (1992) 1.64
The paternal methylation imprint of the mouse H19 locus is acquired in the gonocyte stage during foetal testis development. Genes Cells (2000) 1.56
X-chromosome inactivation: a hypothesis linking ontogeny and phylogeny. Nat Rev Genet (2005) 1.52
N6-methyladenine: the other methylated base of DNA. Bioessays (2006) 1.50
Late DNA replication in the paternally derived X chromosome of female kangaroos. Nature (1971) 1.48
Epigenetic reprogramming in early mammalian development and following somatic nuclear transfer. Semin Cell Dev Biol (2003) 1.44
Intrauterine programming of coronary heart disease and stroke. Acta Paediatr Suppl (1997) 1.42
DNA associated with hyperacetylated histone is preferentially digested by DNase I. Nucleic Acids Res (1978) 1.40
Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells. Nucleic Acids Res (1986) 1.34
Epigenetic risks related to assisted reproductive technologies: epigenetics, imprinting, ART and icebergs? Hum Reprod (2003) 1.33
An ICE pattern crystallizes. Nat Genet (2003) 1.32
The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography. J Biol Chem (1948) 1.28
Deciphering the roles of the histone H2B N-terminal domain in genome-wide transcription. Mol Cell Biol (2006) 1.28
Evidence of evolutionary up-regulation of the single active X chromosome in mammals based on Clc4 expression levels in Mus spretus and Mus musculus. Proc Natl Acad Sci U S A (1997) 1.28
IVF results in de novo DNA methylation and histone methylation at an Igf2-H19 imprinting epigenetic switch. Mol Hum Reprod (2005) 1.22
Disruption of primary imprinting during oocyte growth leads to the modified expression of imprinted genes during embryogenesis. Development (1998) 1.21
Effect of methylation on expression of microinjected genes. Proc Natl Acad Sci U S A (1982) 1.20
Imprint switching for non-random X-chromosome inactivation during mouse oocyte growth. Development (2000) 1.19
Culture of preimplantation embryos and its long-term effects on gene expression and phenotype. Hum Reprod Update (2001) 1.14
Exposure of mouse preimplantation embryos to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters the methylation status of imprinted genes H19 and Igf2. Biol Reprod (2004) 1.11
DNA ticketing theory of memory. Nature (1969) 0.96
Regulation of gene transcription by the histone H2A N-terminal domain. Mol Cell Biol (2007) 0.92
Exposure of preimplantation embryos to insulin alters expression of imprinted genes. Comp Med (2007) 0.82
[Nucleosome differentiation: role of histone H2A variants]. Med Sci (Paris) (2003) 0.76
Physiological and molecular determinants of embryo implantation. Mol Aspects Med (2013) 1.33
Toll-like receptor 4: a potential link between "danger signals," the innate immune system, and preeclampsia? Am J Obstet Gynecol (2005) 1.26
Heparin-binding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotype. Dev Biol (2004) 1.15
Pre-eclampsia and expression of heparin-binding EGF-like growth factor. Lancet (2002) 1.11
Mitochondria: determinants of stem cell fate? Stem Cells Dev (2009) 1.09
Lysophosphatidic acid regulates murine blastocyst development by transactivation of receptors for heparin-binding EGF-like growth factor. Exp Cell Res (2004) 1.01
Environmental and epigenetic effects upon preimplantation embryo metabolism and development. Trends Endocrinol Metab (2011) 1.00
Integrin-mediated adhesion and signaling during blastocyst implantation. Cells Tissues Organs (2002) 0.98
Rapid induction of apoptosis in gastrulating mouse embryos by ethanol and its prevention by HB-EGF. Alcohol Clin Exp Res (2006) 0.96
Integrin signaling regulates blastocyst adhesion to fibronectin at implantation: intracellular calcium transients and vesicle trafficking in primary trophoblast cells. Dev Biol (2002) 0.96
Diverse functions of HBEGF during pregnancy. Mol Reprod Dev (2009) 0.94
Ethanol triggers neural crest apoptosis through the selective activation of a pertussis toxin-sensitive G protein and a phospholipase Cbeta-dependent Ca2+ transient. Alcohol Clin Exp Res (2005) 0.93
Diminished survival of human cytotrophoblast cells exposed to hypoxia/reoxygenation injury and associated reduction of heparin-binding epidermal growth factor-like growth factor. Am J Obstet Gynecol (2008) 0.91
High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples. Hum Reprod (2012) 0.91
Calcitonin down-regulates E-cadherin expression in rodent uterine epithelium during implantation. J Biol Chem (2002) 0.91
Ethanol-induced cephalic apoptosis requires phospholipase C-dependent intracellular calcium signaling. Alcohol Clin Exp Res (2003) 0.90
Trophoblast adhesion of the peri-implantation mouse blastocyst is regulated by integrin signaling that targets phospholipase C. Dev Biol (2006) 0.89
Function-specific intracellular signaling pathways downstream of heparin-binding EGF-like growth factor utilized by human trophoblasts. Biol Reprod (2010) 0.88
Epidermal growth factor-like growth factors prevent apoptosis of alcohol-exposed human placental cytotrophoblast cells. Biol Reprod (2007) 0.87
Cell signaling in trophoblast-uterine communication. Int J Dev Biol (2014) 0.85
Rebuttal: interooplasmic transfers in humans. Reprod Biomed Online (2001) 0.85
Chromosomal instability in rhesus macaque preimplantation embryos. Fertil Steril (2008) 0.85
Incidence of chromosomal mosaicism in morphologically normal nonhuman primate preimplantation embryos. Fertil Steril (2009) 0.85
Rhesus macaque embryos derived from MI oocytes maturing after retrieval display high rates of chromosomal anomalies. Hum Reprod (2008) 0.84
Challenges of primate embryonic stem cell research. Cloning Stem Cells (2005) 0.84
Retrieval of trophoblast cells from the cervical canal for prediction of abnormal pregnancy: a pilot study. Hum Reprod (2009) 0.84
Alpha5beta1, alphaVbeta3 and the platelet-associated integrin alphaIIbbeta3 coordinately regulate adhesion and migration of differentiating mouse trophoblast cells. Dev Biol (2004) 0.82
Histamine enhances cytotrophoblast invasion by inducing intracellular calcium transients through the histamine type-1 receptor. Mol Reprod Dev (2004) 0.82
Transcervical retrieval of fetal cells in the practice of modern medicine: a review of the current literature and future direction. Fertil Steril (2010) 0.81
Soluble HLA-G (sHLA-G) a predictor of IVF outcome? J Assist Reprod Genet (2004) 0.80
Regulation of proteinases during mouse peri-implantation development: urokinase-type plasminogen activator expression and cross talk with matrix metalloproteinase 9. Reproduction (2010) 0.79
Expression of genes for alcohol and aldehyde metabolizing enzymes in mouse oocytes and preimplantation embryos. Reprod Toxicol (2002) 0.79
Apoptosis of alcohol-exposed human placental cytotrophoblast cells is downstream of intracellular calcium signaling. Alcohol Clin Exp Res (2014) 0.78
Life and death responses to trophinin-mediated adhesion during blastocyst implantation. Cell Cycle (2011) 0.77
Expression profiles of cohesins, shugoshins and spindle assembly checkpoint genes in rhesus macaque oocytes predict their susceptibility for aneuploidy during embryonic development. Cell Cycle (2012) 0.76
Identification, molecular characterization, and tissue expression of OVCOV1. Mamm Genome (2002) 0.76
Transcriptional differences between rhesus embryonic stem cells generated from in vitro and in vivo derived embryos. PLoS One (2012) 0.75
Genotyping: the HLA system and embryo development. Reprod Biomed Online (2002) 0.75
Reduced homeobox protein MSX1 in human endometrial tissue is linked to infertility. Hum Reprod (2016) 0.75