Published in Genes Dev on July 15, 2006
Long noncoding RNAs with enhancer-like function in human cells. Cell (2010) 13.00
The functional role of long non-coding RNA in human carcinomas. Mol Cancer (2011) 6.37
MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles. Genome Res (2008) 5.06
Sequencing newly replicated DNA reveals widespread plasticity in human replication timing. Proc Natl Acad Sci U S A (2009) 4.76
Global reorganization of replication domains during embryonic stem cell differentiation. PLoS Biol (2008) 4.50
Noncoding RNA in development. Mamm Genome (2008) 3.42
Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis. Genome Res (2009) 3.36
A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression. EMBO J (2010) 3.18
Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2. Genes Dev (2008) 3.10
Global survey of escape from X inactivation by RNA-sequencing in mouse. Genome Res (2010) 2.87
DNA methylation of the first exon is tightly linked to transcriptional silencing. PLoS One (2011) 2.80
X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations. Proc Natl Acad Sci U S A (2008) 2.53
Regulation and function of DNA methylation in plants and animals. Cell Res (2011) 2.41
DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution. PLoS Genet (2009) 2.37
Genomic imprinting mechanisms in mammals. Mutat Res (2008) 2.28
Dosage compensation in the mouse balances up-regulation and silencing of X-linked genes. PLoS Biol (2007) 2.06
Multimegabase silencing in nucleolar dominance involves siRNA-directed DNA methylation and specific methylcytosine-binding proteins. Mol Cell (2008) 1.94
A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues. PLoS Genet (2011) 1.92
Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells. J Cell Biol (2007) 1.82
Epigenetic mechanisms in mammals. Cell Mol Life Sci (2009) 1.82
Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control. Nat Rev Mol Cell Biol (2011) 1.66
Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice. Nature (2010) 1.64
Genes that escape from X inactivation. Hum Genet (2011) 1.63
Genes that escape X-inactivation in humans have high intraspecific variability in expression, are associated with mental impairment but are not slow evolving. Mol Biol Evol (2013) 1.61
Relics of repeat-induced point mutation direct heterochromatin formation in Neurospora crassa. Genome Res (2008) 1.61
The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis. Epigenetics Chromatin (2009) 1.59
Dosage compensation of the sex chromosomes. Annu Rev Genet (2012) 1.59
X-inactivation reveals epigenetic anomalies in most hESC but identifies sublines that initiate as expected. J Cell Physiol (2008) 1.59
Histone variant macroH2A confers resistance to nuclear reprogramming. EMBO J (2011) 1.57
Dynamic changes in paternal X-chromosome activity during imprinted X-chromosome inactivation in mice. Proc Natl Acad Sci U S A (2009) 1.56
Xist and the order of silencing. EMBO Rep (2007) 1.55
Quantitative genetics of CTCF binding reveal local sequence effects and different modes of X-chromosome association. PLoS Genet (2014) 1.55
Dynamics of gene silencing during X inactivation using allele-specific RNA-seq. Genome Biol (2015) 1.53
Replication timing as an epigenetic mark. Epigenetics (2009) 1.53
Meiotic silencing and the epigenetics of sex. Chromosome Res (2007) 1.52
Do you know the sex of your cells? Am J Physiol Cell Physiol (2013) 1.49
Dosage compensation and demasculinization of X chromosomes in Drosophila. Curr Biol (2010) 1.45
Xist imprinting is promoted by the hemizygous (unpaired) state in the male germ line. Proc Natl Acad Sci U S A (2015) 1.44
Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons. J Neurosci (2008) 1.42
Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids. Nat Genet (2008) 1.41
Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1. Nat Struct Mol Biol (2011) 1.40
DXZ4 chromatin adopts an opposing conformation to that of the surrounding chromosome and acquires a novel inactive X-specific role involving CTCF and antisense transcripts. Genome Res (2008) 1.40
MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency. Nat Commun (2013) 1.39
Escape from X inactivation in mice and humans. Genome Biol (2010) 1.39
Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. Cell Stem Cell (2012) 1.35
The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation. Development (2010) 1.35
Sex chromosome silencing in the marsupial male germ line. Proc Natl Acad Sci U S A (2007) 1.34
Escape from X chromosome inactivation is an intrinsic property of the Jarid1c locus. Proc Natl Acad Sci U S A (2008) 1.34
Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles. RNA (2012) 1.33
Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway. Nat Struct Mol Biol (2013) 1.33
X chromosome inactivation is initiated in human preimplantation embryos. Am J Hum Genet (2009) 1.31
The region homologous to the X-chromosome inactivation centre has been disrupted in marsupial and monotreme mammals. Chromosome Res (2007) 1.27
Chromatin mechanisms in genomic imprinting. Mamm Genome (2009) 1.26
From bacteria to humans, chromatin to elongation, and activation to repression: The expanding roles of noncoding RNAs in regulating transcription. Crit Rev Biochem Mol Biol (2009) 1.23
DNA methylation and normal chromosome behavior in Neurospora depend on five components of a histone methyltransferase complex, DCDC. PLoS Genet (2010) 1.21
Nucleolar dominance and ribosomal RNA gene silencing. Curr Opin Cell Biol (2010) 1.19
Epigenetics in acute myeloid leukemia. Semin Oncol (2008) 1.16
Physical map of two tammar wallaby chromosomes: a strategy for mapping in non-model mammals. Chromosome Res (2008) 1.15
Widespread sex differences in gene expression and splicing in the adult human brain. Nat Commun (2013) 1.15
Epigenetics: definition, mechanisms and clinical perspective. Semin Reprod Med (2009) 1.14
T cell CD40LG gene expression and the production of IgG by autologous B cells in systemic lupus erythematosus. Clin Immunol (2009) 1.13
DLX5 and DLX6 expression is biallelic and not modulated by MeCP2 deficiency. Am J Hum Genet (2007) 1.13
Sex-dimorphic gene expression and ineffective dosage compensation of Z-linked genes in gastrulating chicken embryos. BMC Genomics (2010) 1.11
Epigenetic modifications on X chromosomes in marsupial and monotreme mammals and implications for evolution of dosage compensation. Proc Natl Acad Sci U S A (2010) 1.10
Bipartite structure of the inactive mouse X chromosome. Genome Biol (2015) 1.10
Hsp90 affecting chromatin remodeling might explain transgenerational epigenetic inheritance in Drosophila. Curr Genomics (2008) 1.09
Dosage compensation and gene expression on the mammalian X chromosome: one plus one does not always equal two. Chromosome Res (2009) 1.09
Monoallelic gene expression in mammals. Chromosoma (2009) 1.08
Sex, dose, and equality. PLoS Biol (2007) 1.07
A phosphorylated subpopulation of the histone variant macroH2A1 is excluded from the inactive X chromosome and enriched during mitosis. Proc Natl Acad Sci U S A (2008) 1.07
Whole-genome bisulfite DNA sequencing of a DNMT3B mutant patient. Epigenetics (2012) 1.05
The right dose for every sex. Chromosoma (2006) 1.05
Polycomb group protein Suppressor 2 of zeste is a functional homolog of Posterior Sex Combs. Mol Cell Biol (2008) 1.03
Paternally biased X inactivation in mouse neonatal brain. Genome Biol (2010) 1.03
Caenorhabditis elegans dosage compensation regulates histone H4 chromatin state on X chromosomes. Mol Cell Biol (2012) 1.02
Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammals. PLoS One (2011) 1.01
ATRX marks the inactive X chromosome (Xi) in somatic cells and during imprinted X chromosome inactivation in trophoblast stem cells. Chromosoma (2008) 1.01
A skewed view of X chromosome inactivation. J Clin Invest (2008) 1.01
Epigenetic patterns maintained in early Caenorhabditis elegans embryos can be established by gene activity in the parental germ cells. PLoS Genet (2011) 1.00
The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation. Genome Biol (2015) 0.98
A repetitive elements perspective in Polycomb epigenetics. Front Genet (2012) 0.97
Cell-autonomous sex determination outside of the gonad. Dev Dyn (2013) 0.97
Specific patterns of histone marks accompany X chromosome inactivation in a marsupial. Chromosome Res (2009) 0.97
Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cells. Cell (2012) 0.97
X chromosome-wide analyses of genomic DNA methylation states and gene expression in male and female neutrophils. Proc Natl Acad Sci U S A (2010) 0.97
Chromosome-wide profiling of X-chromosome inactivation and epigenetic states in fetal brain and placenta of the opossum, Monodelphis domestica. Genome Res (2013) 0.97
Lineage-specific function of the noncoding Tsix RNA for Xist repression and Xi reactivation in mice. Genes Dev (2011) 0.96
Characterization of the bovine pseudoautosomal boundary: Documenting the evolutionary history of mammalian sex chromosomes. Genome Res (2008) 0.96
Interactions between age, sex, and hormones in experimental ischemic stroke. Neurochem Int (2012) 0.96
A mammal-specific Doublesex homolog associates with male sex chromatin and is required for male meiosis. PLoS Genet (2007) 0.95
High resolution profiling of human exon methylation by liquid hybridization capture-based bisulfite sequencing. BMC Genomics (2011) 0.94
Nuclear organization and dosage compensation. Cold Spring Harb Perspect Biol (2010) 0.94
The opossum genome: insights and opportunities from an alternative mammal. Genome Res (2008) 0.94
Identification and characterization of novel genotoxic stress-inducible nuclear long noncoding RNAs in mammalian cells. PLoS One (2012) 0.93
Function of the sex chromosomes in mammalian fertility. Cold Spring Harb Perspect Biol (2011) 0.92
Conceptual frameworks and mouse models for studying sex differences in physiology and disease: why compensation changes the game. Exp Neurol (2014) 0.92
Allele-specific distribution of RNA polymerase II on female X chromosomes. Hum Mol Genet (2011) 0.91
Quantitatively imaging chromosomes by correlated cryo-fluorescence and soft x-ray tomographies. Biophys J (2014) 0.91
Sex modifies genetic effects on residual variance in urinary calcium excretion in rat (Rattus norvegicus). Genetics (2012) 0.91
Female bias in Rhox6 and 9 regulation by the histone demethylase KDM6A. PLoS Genet (2013) 0.91
CTCF physically links cohesin to chromatin. Proc Natl Acad Sci U S A (2008) 4.89
Dosage compensation of the active X chromosome in mammals. Nat Genet (2005) 4.31
Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development. Dev Cell (2005) 3.32
Global survey of escape from X inactivation by RNA-sequencing in mouse. Genome Res (2010) 2.87
Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice. Nature (2005) 2.46
Identification of a novel gene on chromosome 7q11.2 interrupted by a translocation breakpoint in a pair of autistic twins. Genomics (2002) 2.16
Evidence for compensatory upregulation of expressed X-linked genes in mammals, Caenorhabditis elegans and Drosophila melanogaster. Nat Genet (2011) 2.07
Genes that escape from X inactivation. Hum Genet (2011) 1.63
Mammalian X upregulation is associated with enhanced transcription initiation, RNA half-life, and MOF-mediated H4K16 acetylation. Dev Cell (2013) 1.61
Sex-specific expression of the X-linked histone demethylase gene Jarid1c in brain. PLoS One (2008) 1.51
Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons. J Neurosci (2008) 1.42
Escape from X inactivation in mice and humans. Genome Biol (2010) 1.39
Comparative sequence and x-inactivation analyses of a domain of escape in human xp11.2 and the conserved segment in mouse. Genome Res (2004) 1.29
High expression of the mammalian X chromosome in brain. Brain Res (2006) 1.17
Sex differences in brain expression of X- and Y-linked genes. Brain Res (2006) 1.16
Genome-wide distribution of macroH2A1 histone variants in mouse liver chromatin. Mol Cell Biol (2010) 1.15
TSPY, the candidate gonadoblastoma gene on the human Y chromosome, has a widely expressed homologue on the X - implications for Y chromosome evolution. Chromosome Res (2004) 1.14
Does gene dosage really matter? J Biol (2007) 0.97
Genomic responses to abnormal gene dosage: the X chromosome improved on a common strategy. PLoS Biol (2010) 0.93
Dosage regulation of the active X chromosome in human triploid cells. PLoS Genet (2009) 0.92
Female bias in Rhox6 and 9 regulation by the histone demethylase KDM6A. PLoS Genet (2013) 0.91
A balancing act between the X chromosome and the autosomes. J Biol (2006) 0.91
Loss of maternal CTCF is associated with peri-implantation lethality of Ctcf null embryos. PLoS One (2012) 0.91
The leukemia-associated gene Mllt1/ENL: characterization of a murine homolog and demonstration of an essential role in embryonic development. Blood Cells Mol Dis (2002) 0.90
Characterization of the OFD1/Ofd1 genes on the human and mouse sex chromosomes and exclusion of Ofd1 for the Xpl mouse mutant. Genomics (2003) 0.90
Isolation, X location and activity of the marsupial homologue of SLC16A2, an XIST-flanking gene in eutherian mammals. Chromosome Res (2005) 0.86
Differential association of SMC1alpha and SMC3 proteins with meiotic chromosomes in wild-type and SPO11-deficient male mice. Chromosome Res (2002) 0.81
Silence of the fathers: early X inactivation. Bioessays (2004) 0.81
Phenotype and X inactivation in 45,X/46,X,r(X) cases. Am J Med Genet A (2004) 0.80
The not-so-silent X. Nat Genet (2008) 0.80
Clcn4-2 genomic structure differs between the X locus in Mus spretus and the autosomal locus in Mus musculus: AT motif enrichment on the X. Genome Res (2011) 0.79
Decoding dosage compensation. Genome Biol (2007) 0.75