Published in Nat Methods on August 30, 2009
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Imaging and quantifying the morphology of an organic-inorganic nanoparticle at the sub-nanometre level. Nat Nanotechnol (2010) 1.04
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Irreversible effect of cysteine protease inhibitors on the release of malaria parasites from infected erythrocytes. Cell Microbiol (2008) 1.24
Probing the macromolecular organization of cells by electron tomography. Curr Opin Cell Biol (2009) 1.22
STEM tomography for thick biological specimens. Ultramicroscopy (2008) 1.16
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Monte Carlo electron-trajectory simulations in bright-field and dark-field STEM: implications for tomography of thick biological sections. Ultramicroscopy (2008) 1.04
Three-dimensional localization of ultrasmall immuno-gold labels by HAADF-STEM tomography. J Struct Biol (2002) 0.99
Reconstructing mammalian membrane architecture by large area cellular tomography. Methods Cell Biol (2007) 0.97
Automated most-probable loss tomography of thick selectively stained biological specimens with quantitative measurement of resolution improvement. J Struct Biol (2004) 0.93
A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR. Proc Natl Acad Sci U S A (2002) 9.55
Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils. Science (2005) 8.86
Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils. Proc Natl Acad Sci U S A (2008) 4.84
Dynamic clustered distribution of hemagglutinin resolved at 40 nm in living cell membranes discriminates between raft theories. Proc Natl Acad Sci U S A (2007) 4.58
Dynamics of putative raft-associated proteins at the cell surface. J Cell Biol (2004) 4.52
GTPase cycle of dynamin is coupled to membrane squeeze and release, leading to spontaneous fission. Cell (2008) 3.69
The pentacovalent phosphorus intermediate of a phosphoryl transfer reaction. Science (2003) 3.41
Protein oxidation implicated as the primary determinant of bacterial radioresistance. PLoS Biol (2007) 3.22
Membrane transformation during malaria parasite release from human red blood cells. Curr Biol (2005) 2.53
Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery. ACS Nano (2009) 2.39
Supramolecular structural constraints on Alzheimer's beta-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance. Biochemistry (2002) 2.37
Line tension and interaction energies of membrane rafts calculated from lipid splay and tilt. Biophys J (2004) 2.35
Layer-specific variation of iron content in cerebral cortex as a source of MRI contrast. Proc Natl Acad Sci U S A (2010) 2.33
Progressive ordering with decreasing temperature of the phospholipids of influenza virus. Nat Chem Biol (2008) 2.33
A facile nonviral method for delivering genes and siRNAs to skeletal muscle of mammalian limbs. Mol Ther (2004) 2.16
Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure. Proc Natl Acad Sci U S A (2009) 2.15
Membranes of the world unite! J Cell Biol (2006) 2.06
Organization of the core structure of the postsynaptic density. Proc Natl Acad Sci U S A (2008) 2.06
Bax-type apoptotic proteins porate pure lipid bilayers through a mechanism sensitive to intrinsic monolayer curvature. J Biol Chem (2002) 2.00
Geometric catalysis of membrane fission driven by flexible dynamin rings. Science (2013) 1.95
Insulin stimulates the halting, tethering, and fusion of mobile GLUT4 vesicles in rat adipose cells. J Cell Biol (2005) 1.93
SNARE-mediated lipid mixing depends on the physical state of the vesicles. Biophys J (2005) 1.91
Large intestine-targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection. Nat Med (2012) 1.74
Quantitative electron microscopy and fluorescence spectroscopy of the membrane distribution of influenza hemagglutinin. J Cell Biol (2005) 1.70
Oligomeric structure of the human immunodeficiency virus type 1 envelope protein on the virion surface. J Virol (2002) 1.69
Mass of the postsynaptic density and enumeration of three key molecules. Proc Natl Acad Sci U S A (2005) 1.67
An invasive podosome-like structure promotes fusion pore formation during myoblast fusion. J Cell Biol (2010) 1.59
Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells. J Transl Med (2008) 1.54
Collective cell migration requires vesicular trafficking for chemoattractant delivery at the trailing edge. J Cell Biol (2008) 1.48
Caught in the act: the structure of phosphorylated beta-phosphoglucomutase from Lactococcus lactis. Biochemistry (2002) 1.43
Cell-cell and cell-extracellular matrix interactions regulate embryonic stem cell differentiation. Stem Cells (2007) 1.41
Insulin controls the spatial distribution of GLUT4 on the cell surface through regulation of its postfusion dispersal. Cell Metab (2010) 1.36
PSD-95 is required to sustain the molecular organization of the postsynaptic density. J Neurosci (2011) 1.33
Initial loss but later excess of GABAergic synapses with dentate granule cells in a rat model of temporal lobe epilepsy. J Comp Neurol (2010) 1.30
Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals. Proc Natl Acad Sci U S A (2004) 1.27
Direct chemical evidence for sphingolipid domains in the plasma membranes of fibroblasts. Proc Natl Acad Sci U S A (2013) 1.26
Mechanism of plasmid delivery by hydrodynamic tail vein injection. I. Hepatocyte uptake of various molecules. J Gene Med (2006) 1.25
Irreversible effect of cysteine protease inhibitors on the release of malaria parasites from infected erythrocytes. Cell Microbiol (2008) 1.24
Chimeric ferritin nanocages for multiple function loading and multimodal imaging. Nano Lett (2011) 1.24
Golgi fragmentation is associated with ceramide-induced cellular effects. Mol Biol Cell (2005) 1.21
Analysis of the substrate specificity loop of the HAD superfamily cap domain. Biochemistry (2004) 1.20
Lipid polymorphisms and membrane shape. Cold Spring Harb Perspect Biol (2011) 1.19
Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas. Proc Natl Acad Sci U S A (2006) 1.18
De novo sequencing of peptides using MALDI/TOF-TOF. J Am Soc Mass Spectrom (2002) 1.17
Competition between Blown fuse and WASP for WIP binding regulates the dynamics of WASP-dependent actin polymerization in vivo. Dev Cell (2011) 1.14
Sphingolipid domains in the plasma membranes of fibroblasts are not enriched with cholesterol. J Biol Chem (2013) 1.14
Mesenchymal stem cell-based cell engineering with multifunctional mesoporous silica nanoparticles for tumor delivery. Biomaterials (2012) 1.13
Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors. J Transl Med (2009) 1.11
Vesicle formation by self-assembly of membrane-bound matrix proteins into a fluidlike budding domain. J Cell Biol (2007) 1.10
Long-term multimodal imaging of tumor draining sentinel lymph nodes using mesoporous silica-based nanoprobes. Biomaterials (2012) 1.09
Large-scale production of pseudotyped lentiviral vectors using baculovirus GP64. Hum Gene Ther (2003) 1.08
Cytotoxicity mediated by the Fas ligand (FasL)-activated apoptotic pathway in stem cells. J Biol Chem (2009) 1.08
Shape bistability of a membrane neck: a toggle switch to control vesicle content release. Proc Natl Acad Sci U S A (2003) 1.08
New stages in the program of malaria parasite egress imaged in normal and sickle erythrocytes. Curr Biol (2010) 1.07
Reversible stages of the low-pH-triggered conformational change in influenza virus hemagglutinin. EMBO J (2002) 1.07
Endocytosis: curvature to the ENTH degree. Curr Biol (2002) 1.07
Chemical confirmation of a pentavalent phosphorane in complex with beta-phosphoglucomutase. J Am Chem Soc (2005) 1.05
Mechanism of plasmid delivery by hydrodynamic tail vein injection. II. Morphological studies. J Gene Med (2006) 1.04
Distribution and clearance of PEG-single-walled carbon nanotube cancer drug delivery vehicles in mice. Nanomedicine (Lond) (2010) 1.04
Analysis of the structural determinants underlying discrimination between substrate and solvent in beta-phosphoglucomutase catalysis. Biochemistry (2009) 1.04
Actin mediates the nanoscale membrane organization of the clustered membrane protein influenza hemagglutinin. Biophys J (2013) 1.03
Promoting trimerization of soluble human immunodeficiency virus type 1 (HIV-1) Env through the use of HIV-1/simian immunodeficiency virus chimeras. J Virol (2004) 1.03
Perforin-like protein PPLP2 permeabilizes the red blood cell membrane during egress of Plasmodium falciparum gametocytes. Cell Microbiol (2014) 1.02
Cholesterol promotes hemifusion and pore widening in membrane fusion induced by influenza hemagglutinin. J Gen Physiol (2008) 1.01
Lateral tension increases the line tension between two domains in a lipid bilayer membrane. Phys Rev E Stat Nonlin Soft Matter Phys (2007) 1.01
Synaptotagmin: fusogenic role for calcium sensor? Nat Struct Mol Biol (2006) 1.01
Solution structure of Alg13: the sugar donor subunit of a yeast N-acetylglucosamine transferase. Structure (2008) 1.00
Alkaline ceramidase 2 regulates beta1 integrin maturation and cell adhesion. FASEB J (2008) 1.00
Multilineage differentiation of rhesus monkey embryonic stem cells in three-dimensional culture systems. Stem Cells (2003) 1.00
Evaluation of hydrodynamic limb vein injections in nonhuman primates. Hum Gene Ther (2010) 0.98
Quantification of malaria parasite release from infected erythrocytes: inhibition by protein-free media. Malar J (2007) 0.98
Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5. Oncotarget (2013) 0.97
Shear forces during blast, not abrupt changes in pressure alone, generate calcium activity in human brain cells. PLoS One (2012) 0.97
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Domain-driven morphogenesis of cellular membranes. Curr Biol (2009) 0.97
Quantitative femto- to attomole immunodetection of regulated secretory vesicle proteins critical to exocytosis. Anal Biochem (2002) 0.97
The deceptive nature of UVA tanning versus the modest protective effects of UVB tanning on human skin. Pigment Cell Melanoma Res (2010) 0.97
Group I PAKs function downstream of Rac to promote podosome invasion during myoblast fusion in vivo. J Cell Biol (2012) 0.96
Regulated secretion: SNARE density, vesicle fusion and calcium dependence. J Cell Sci (2003) 0.96
Quantitative STEM mass measurement of biological macromolecules in a 300 kV TEM. J Microsc (2007) 0.96
Cytoplasmic free Ca2+ is essential for multiple steps in malaria parasite egress from infected erythrocytes. Malar J (2013) 0.95
In vitro evidence for the dual function of Alg2 and Alg11: essential mannosyltransferases in N-linked glycoprotein biosynthesis. Biochemistry (2006) 0.95
Manipulating the power of an additional phase: a flower-like Au-Fe3O4 optical nanosensor for imaging protease expressions in vivo. ACS Nano (2011) 0.95
Use of Evans blue dye to compare limb muscles in exercised young and old mdx mice. Muscle Nerve (2010) 0.94
Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice. Am J Physiol Endocrinol Metab (2012) 0.93
Insulin regulates fusion of GLUT4 vesicles independent of Exo70-mediated tethering. J Biol Chem (2009) 0.93
Dual-axis electron tomography of biological specimens: Extending the limits of specimen thickness with bright-field STEM imaging. J Struct Biol (2010) 0.92
Invasion of human tissue ex vivo by Borrelia burgdorferi. J Infect Dis (2005) 0.92
Cooperative elastic stresses, the hydrophobic effect, and lipid tilt in membrane remodeling. FEBS Lett (2010) 0.91