Published in J Phys Chem B on September 24, 2009
Electron spin-echo envelope modulation (ESEEM) reveals water and phosphate interactions with the KcsA potassium channel. Biochemistry (2010) 0.90
Probing water density and dynamics in the chaperonin GroEL cavity. J Am Chem Soc (2014) 0.80
Monte Carlo simulations of peptide-membrane interactions with the MCPep web server. Nucleic Acids Res (2012) 0.79
Perspective of Use of Antiviral Peptides against Influenza Virus. Viruses (2015) 0.79
The Transmembrane Helix Tilt May Be Determined by the Balance between Precession Entropy and Lipid Perturbation. J Chem Theory Comput (2012) 0.75
ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures. Nucleic Acids Res (2005) 10.60
ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids. Nucleic Acids Res (2010) 9.68
ConSurf: identification of functional regions in proteins by surface-mapping of phylogenetic information. Bioinformatics (2003) 7.83
Rate4Site: an algorithmic tool for the identification of functional regions in proteins by surface mapping of evolutionary determinants within their homologues. Bioinformatics (2002) 4.54
Comparison of site-specific rate-inference methods for protein sequences: empirical Bayesian methods are superior. Mol Biol Evol (2004) 3.62
The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance. Purinergic Signal (2006) 3.52
ConSeq: the identification of functionally and structurally important residues in protein sequences. Bioinformatics (2004) 3.50
Purinergic signalling in the nervous system: an overview. Trends Neurosci (2008) 2.86
Targeted disruption of cd73/ecto-5'-nucleotidase alters thromboregulation and augments vascular inflammatory response. Circ Res (2004) 2.68
Comment on "Network motifs: simple building blocks of complex networks" and "Superfamilies of evolved and designed networks". Science (2004) 2.37
Ultrashort antibacterial and antifungal lipopeptides. Proc Natl Acad Sci U S A (2006) 2.15
The ConSurf-DB: pre-calculated evolutionary conservation profiles of protein structures. Nucleic Acids Res (2008) 2.04
A putative molecular-activation switch in the transmembrane domain of erbB2. Proc Natl Acad Sci U S A (2002) 1.86
Endotoxin (lipopolysaccharide) neutralization by innate immunity host-defense peptides. Peptide properties and plausible modes of action. J Biol Chem (2005) 1.72
The ConSurf-HSSP database: the mapping of evolutionary conservation among homologs onto PDB structures. Proteins (2005) 1.72
T-cell inactivation and immunosuppressive activity induced by HIV gp41 via novel interacting motif. FASEB J (2006) 1.57
A Calpha model for the transmembrane alpha helices of gap junction intercellular channels. Mol Cell (2004) 1.54
Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy. Nat Genet (2006) 1.51
Conjugation of a magainin analogue with lipophilic acids controls hydrophobicity, solution assembly, and cell selectivity. Biochemistry (2002) 1.49
Quasi-symmetry in the cryo-EM structure of EmrE provides the key to modeling its transmembrane domain. J Mol Biol (2006) 1.47
Identification of DNA-binding proteins using structural, electrostatic and evolutionary features. J Mol Biol (2009) 1.43
Can we predict biological activity of antimicrobial peptides from their interactions with model phospholipid membranes? Peptides (2003) 1.42
Extracellular nucleotide signaling in adult neural stem cells: synergism with growth factor-mediated cellular proliferation. Development (2006) 1.41
New lytic peptides based on the D,L-amphipathic helix motif preferentially kill tumor cells compared to normal cells. Biochemistry (2003) 1.37
Immunoisolation of two synaptic vesicle pools from synaptosomes: a proteomics analysis. J Neurochem (2005) 1.37
The ecto-nucleoside triphosphate diphosphohydrolase NTPDase2/CD39L1 is expressed in a novel functional compartment within the liver. Hepatology (2002) 1.34
Exploring peptide membrane interaction using surface plasmon resonance: differentiation between pore formation versus membrane disruption by lytic peptides. Biochemistry (2003) 1.33
Measurement of the conductance of single conjugated molecules. Nature (2005) 1.33
Model structure of the Na+/H+ exchanger 1 (NHE1): functional and clinical implications. J Biol Chem (2007) 1.32
Polyoxometalates--a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors. Bioorg Med Chem Lett (2006) 1.32
Expression of the ecto-ATPase NTPDase2 in the germinal zones of the developing and adult rat brain. Eur J Neurosci (2003) 1.31
Distribution of ectonucleotidases in the rodent brain revisited. Cell Tissue Res (2008) 1.31
Detection of functionally important regions in "hypothetical proteins" of known structure. Structure (2008) 1.31
The consequence of sequence alteration of an amphipathic alpha-helical antimicrobial peptide and its diastereomers. J Biol Chem (2002) 1.30
A novel scoring function for predicting the conformations of tightly packed pairs of transmembrane alpha-helices. J Mol Biol (2002) 1.29
Lipopolysaccharide (Endotoxin)-host defense antibacterial peptides interactions: role in bacterial resistance and prevention of sepsis. Biochim Biophys Acta (2006) 1.29
Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists. J Med Chem (2002) 1.26
Targeting the voltage sensor of Kv7.2 voltage-gated K+ channels with a new gating-modifier. Proc Natl Acad Sci U S A (2010) 1.26
Bestowing antifungal and antibacterial activities by lipophilic acid conjugation to D,L-amino acid-containing antimicrobial peptides: a plausible mode of action. Biochemistry (2003) 1.25
Co-evolving residues in membrane proteins. Bioinformatics (2007) 1.25
A putative mechanism for downregulation of the catalytic activity of the EGF receptor via direct contact between its kinase and C-terminal domains. Structure (2004) 1.24
Energetics of ErbB1 transmembrane domain dimerization in lipid bilayers. Biophys J (2009) 1.24
A new group of antifungal and antibacterial lipopeptides derived from non-membrane active peptides conjugated to palmitic acid. J Biol Chem (2004) 1.23
A molecular mechanism for lipopolysaccharide protection of Gram-negative bacteria from antimicrobial peptides. J Biol Chem (2005) 1.23
Trophic functions of nucleotides in the central nervous system. Trends Neurosci (2009) 1.21
Antimicrobial lipopolypeptides composed of palmitoyl Di- and tricationic peptides: in vitro and in vivo activities, self-assembly to nanostructures, and a plausible mode of action. Biochemistry (2008) 1.19
Effect of drastic sequence alteration and D-amino acid incorporation on the membrane binding behavior of lytic peptides. Biochemistry (2004) 1.18
Stress-protective signalling of prion protein is corrupted by scrapie prions. EMBO J (2008) 1.18
The conserved carboxy terminus of the capsid domain of human immunodeficiency virus type 1 gag protein is important for virion assembly and release. J Virol (2004) 1.18
Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide. Cancer Res (2006) 1.18
In silico identification of functional regions in proteins. Bioinformatics (2005) 1.18
Transmembrane domains interactions within the membrane milieu: principles, advances and challenges. Biochim Biophys Acta (2011) 1.16
Suppression of human prostate tumor growth in mice by a cytolytic D-, L-amino Acid Peptide: membrane lysis, increased necrosis, and inhibition of prostate-specific antigen secretion. Cancer Res (2004) 1.15
Cloning, purification, and identification of the liver canalicular ecto-ATPase as NTPDase8. Am J Physiol Gastrointest Liver Physiol (2006) 1.14
Expression of NTPDase1 and NTPDase2 in murine kidney: relevance to regulation of P2 receptor signaling. Am J Physiol Renal Physiol (2005) 1.14
Demonstrating the C-terminal boundary of the HIV 1 fusion conformation in a dynamic ongoing fusion process and implication for fusion inhibition. FASEB J (2007) 1.14
Increased concentration of polyvalent phospholipids in the adsorption domain of a charged protein. Biophys J (2004) 1.14
Two motifs within a transmembrane domain, one for homodimerization and the other for heterodimerization. J Biol Chem (2004) 1.14
Transmembrane protein structures without X-rays. Trends Biochem Sci (2006) 1.13
Specificity in transmembrane helix-helix interactions mediated by aromatic residues. J Biol Chem (2007) 1.13
Ecto-5'-nucleotidase (cd73)-dependent and -independent generation of adenosine participates in the mediation of tubuloglomerular feedback in vivo. Am J Physiol Renal Physiol (2006) 1.13
Association of the ecto-ATPase NTPDase2 with glial cells of the peripheral nervous system. Glia (2004) 1.12
Viral fusion proteins: multiple regions contribute to membrane fusion. Biochim Biophys Acta (2003) 1.12
The stability of the intact envelope glycoproteins is a major determinant of sensitivity of HIV/SIV to peptidic fusion inhibitors. J Mol Biol (2004) 1.10
Gd3+ complexes as potential spin labels for high field pulsed EPR distance measurements. J Am Chem Soc (2007) 1.10
Dynamic equilibrium between multiple active and inactive conformations explains regulation and oncogenic mutations in ErbB receptors. Biochim Biophys Acta (2007) 1.10
Free diffusion of steroid hormones across biomembranes: a simplex search with implicit solvent model calculations. Biophys J (2004) 1.10
A novel lytic peptide composed of DL-amino acids selectively kills cancer cells in culture and in mice. J Biol Chem (2003) 1.10
QuasiMotiFinder: protein annotation by searching for evolutionarily conserved motif-like patterns. Nucleic Acids Res (2005) 1.09
Structurally altered peptides reveal an important role for N-terminal heptad repeat binding and stability in the inhibitory action of HIV-1 peptide DP178. J Biol Chem (2006) 1.09
The chirality of a twist-bend nematic phase identified by NMR spectroscopy. J Phys Chem B (2012) 1.09
Disruption of the Aspergillus fumigatus ECM33 homologue results in rapid conidial germination, antifungal resistance and hypervirulence. Microbiology (2006) 1.08
Lipid clustering by three homologous arginine-rich antimicrobial peptides is insensitive to amino acid arrangement and induced secondary structure. Biochim Biophys Acta (2010) 1.08
Thermodynamics of melittin binding to lipid bilayers. Aggregation and pore formation. Biochemistry (2009) 1.07
A Myo6 mutation destroys coordination between the myosin heads, revealing new functions of myosin VI in the stereocilia of mammalian inner ear hair cells. PLoS Genet (2008) 1.07
Localization of SNARE proteins and secretory organelle proteins in astrocytes in vitro and in situ. Neurosci Res (2004) 1.07
A synergism between temporins toward Gram-negative bacteria overcomes resistance imposed by the lipopolysaccharide protective layer. J Biol Chem (2006) 1.06
Conjugation of fatty acids with different lengths modulates the antibacterial and antifungal activity of a cationic biologically inactive peptide. Biochem J (2005) 1.06
Type I chaperonins: not all are created equal. FEBS Lett (2002) 1.05
Controlled alteration of the shape and conformational stability of alpha-helical cell-lytic peptides: effect on mode of action and cell specificity. Biochem J (2005) 1.05
D-alanylation of lipoteichoic acids confers resistance to cationic peptides in group B streptococcus by increasing the cell wall density. PLoS Pathog (2012) 1.05
A structural model of the copper ATPase ATP7B to facilitate analysis of Wilson disease-causing mutations and studies of the transport mechanism. Metallomics (2012) 1.05
Analysis of the synaptic vesicle proteome using three gel-based protein separation techniques. Proteomics (2006) 1.05
Short native antimicrobial peptides and engineered ultrashort lipopeptides: similarities and differences in cell specificities and modes of action. Cell Mol Life Sci (2011) 1.04
In vitro activity and potency of an intravenously injected antimicrobial peptide and its DL amino acid analog in mice infected with bacteria. Antimicrob Agents Chemother (2004) 1.04
New model of cystic fibrosis transmembrane conductance regulator proposes active channel-like conformation. J Chem Inf Model (2012) 1.03
Gadolinium tagging for high-precision measurements of 6 nm distances in protein assemblies by EPR. J Am Chem Soc (2011) 1.02
Characterization of the HIV N-terminal fusion peptide-containing region in context of key gp41 fusion conformations. J Biol Chem (2006) 1.02
Stereochemistry of glutamate receptor agonist efficacy: engineering a dual-specificity AMPA/kainate receptor. Biochemistry (2004) 1.02
A capillary electrophoresis method for the characterization of ecto-nucleoside triphosphate diphosphohydrolases (NTPDases) and the analysis of inhibitors by in-capillary enzymatic microreaction. Purinergic Signal (2005) 1.01
Quality assessment of protein model-structures using evolutionary conservation. Bioinformatics (2010) 1.01
Inhibition of fungal and bacterial plant pathogens in vitro and in planta with ultrashort cationic lipopeptides. Appl Environ Microbiol (2007) 1.01
pH-dependent antifungal lipopeptides and their plausible mode of action. Biochemistry (2005) 1.01
Carboxylate binding in copper histidine complexes in solution and in zeolite Y: X- and W-band pulsed EPR/ENDOR combined with DFT calculations. J Am Chem Soc (2004) 1.01
Functional and structural characterization of HIV-1 gp41 ectodomain regions in phospholipid membranes suggests that the fusion-active conformation is extended. J Mol Biol (2006) 1.00
Interactions of hydrophobic peptides with lipid bilayers: Monte Carlo simulations with M2delta. Biophys J (2003) 1.00
Oncolytic activities of host defense peptides. Int J Mol Sci (2011) 1.00