Utility of transplantation in studying adipocyte biogenesis and function.

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Published in Mol Cell Endocrinol on September 04, 2009

Authors

Yiying Zhang1

Author Affiliations

1: Division of Molecular Genetics, Department of Pediatrics, Columbia University, New York, NY 10032, USA. yz84@columbia.edu

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Multilineage potential of adult human mesenchymal stem cells. Science (1999) 66.19

Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest (2003) 41.22

Positional cloning of the mouse obese gene and its human homologue. Nature (1994) 38.85

Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng (2001) 20.65

Identification and importance of brown adipose tissue in adult humans. N Engl J Med (2009) 20.57

Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell (1994) 17.58

Marrow stromal cells as stem cells for nonhematopoietic tissues. Science (1997) 17.06

Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med (1996) 16.98

Central nervous system control of food intake. Nature (2000) 15.85

The hormone resistin links obesity to diabetes. Nature (2001) 15.49

PRDM16 controls a brown fat/skeletal muscle switch. Nature (2008) 13.08

Dynamics of fat cell turnover in humans. Nature (2008) 9.80

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med (2001) 9.68

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science (1995) 9.09

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature (2002) 8.77

Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J Clin Invest (2007) 8.71

Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev (2000) 8.15

Role of leptin in the neuroendocrine response to fasting. Nature (1996) 8.02

Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature (1997) 7.33

Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N Engl J Med (1999) 6.94

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature (2008) 6.82

Identification of white adipocyte progenitor cells in vivo. Cell (2008) 6.58

White fat progenitor cells reside in the adipose vasculature. Science (2008) 6.49

Increased adipose tissue in male and female estrogen receptor-alpha knockout mice. Proc Natl Acad Sci U S A (2000) 5.47

Beneficial effects of subcutaneous fat transplantation on metabolism. Cell Metab (2008) 5.07

Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex. Nature (2009) 4.98

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy. Genes Dev (1998) 4.86

Regional distribution of body fat, plasma lipoproteins, and cardiovascular disease. Arteriosclerosis (1990) 4.01

Selective deletion of leptin receptor in neurons leads to obesity. J Clin Invest (2001) 3.82

Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation. Proc Natl Acad Sci U S A (2004) 3.45

Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice. J Clin Invest (2000) 3.41

Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice. Proc Natl Acad Sci U S A (2007) 3.40

Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes. J Clin Invest (2005) 3.29

Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells. J Cell Physiol (1999) 3.21

Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity. Proc Natl Acad Sci U S A (2000) 2.83

Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage. Proc Natl Acad Sci U S A (2004) 2.56

Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells. J Clin Invest (2006) 2.40

Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue. Diabetologia (2007) 2.34

Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways. J Biol Chem (2005) 2.33

Formation of normally differentiated subcutaneous fat pads by an established preadipose cell line. J Cell Physiol (1979) 2.27

Depot-specific hormonal characteristics of subcutaneous and visceral adipose tissue and their relation to the metabolic syndrome. Horm Metab Res (2003) 2.16

Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots. Am J Physiol Endocrinol Metab (2004) 2.16

Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis. Circ Res (2003) 2.12

Decreased brown fat markedly enhances susceptibility to diet-induced obesity, diabetes, and hyperlipidemia. Endocrinology (1996) 1.99

Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk. Am J Med (2007) 1.99

Cellularity of rat adipose tissue: effects of growth, starvation, and obesity. J Lipid Res (1969) 1.97

Fatty acid analysis of transplanted adipose tissue. Arch Dermatol (2001) 1.95

Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation. J Clin Invest (1997) 1.95

Effect of insulin resistance, dyslipidemia, and intra-abdominal adiposity on the development of cardiovascular disease and diabetes mellitus. Am J Med (2007) 1.93

Waist circumference and cardiometabolic risk: a consensus statement from shaping America's health: Association for Weight Management and Obesity Prevention; NAASO, the Obesity Society; the American Society for Nutrition; and the American Diabetes Association. Diabetes Care (2007) 1.85

Cellularity of adipose depots in six strains of genetically obese mice. J Lipid Res (1972) 1.84

Leptin accelerates the onset of puberty in normal female mice. J Clin Invest (1997) 1.80

Disruption of peripheral leptin signaling in mice results in hyperleptinemia without associated metabolic abnormalities. Endocrinology (2007) 1.73

Effect of age, sex, and sites on the cellularity of the adipose tissue in mice and rats rendered obese by a high-fat diet. J Clin Invest (1972) 1.70

Novel form of lipolysis induced by leptin. J Biol Chem (1999) 1.67

Visceral adipose tissue inflammation accelerates atherosclerosis in apolipoprotein E-deficient mice. Circulation (2008) 1.62

The role of leptin in the control of body weight. Nutr Rev (2002) 1.61

Effects of weight change on plasma leptin concentrations and energy expenditure. J Clin Endocrinol Metab (1997) 1.60

Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation. Proc Natl Acad Sci U S A (1997) 1.59

Differentiation-dependent stimulation of neovascularization and endothelial cell chemotaxis by 3T3 adipocytes. Proc Natl Acad Sci U S A (1982) 1.58

Age-related adipose tissue mRNA expression of ADD1/SREBP1, PPARgamma, lipoprotein lipase, and GLUT4 glucose transporter in rhesus monkeys. J Gerontol A Biol Sci Med Sci (1999) 1.56

Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes. Proc Natl Acad Sci U S A (1997) 1.55

Identification of oestrogen receptors and oestrogen receptor mRNA in human adipose tissue. Eur J Clin Invest (1996) 1.53

Sympathetic innervation of white adipose tissue and its regulation of fat cell number. Am J Physiol Regul Integr Comp Physiol (2004) 1.48

Preadipocyte transplantation: an in vivo study of direct leptin signaling on adipocyte morphogenesis and cell size. Am J Physiol Regul Integr Comp Physiol (2009) 1.47

Autologous fat transplants influence compensatory white adipose tissue mass increases after lipectomy. Am J Physiol Regul Integr Comp Physiol (2003) 1.46

Impaired expression and functional activity of the beta 3- and beta 1-adrenergic receptors in adipose tissue of congenitally obese (C57BL/6J ob/ob) mice. Mol Endocrinol (1994) 1.45

Effects of white adipose tissue grafts on total body fat and cellularity are dependent on graft type and location. Am J Physiol Regul Integr Comp Physiol (2005) 1.45

Depot-related gene expression in human subcutaneous and omental adipocytes. Diabetes (1998) 1.43

A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. V. Rising leptin levels may signal the onset of puberty. J Clin Endocrinol Metab (1997) 1.42

Fat depot-related differences in gene expression, adiponectin secretion, and insulin action and signalling in human adipocytes differentiated in vitro from precursor stromal cells. Diabetologia (2007) 1.42

Altered expression of C/EBP family members results in decreased adipogenesis with aging. Am J Physiol Regul Integr Comp Physiol (2001) 1.40

Comparison of proliferation and differentiation capacity of human adipocyte precursor cells from the omental and subcutaneous adipose tissue depot of obese subjects. Metabolism (2004) 1.38

A novel preadipocyte cell line established from mouse adult mature adipocytes. Biochem Biophys Res Commun (2004) 1.36

Age, anatomic site, and the replication and differentiation of adipocyte precursors. Am J Physiol (1990) 1.33

Activation of the nuclear receptor peroxisome proliferator-activated receptor gamma promotes brown adipocyte differentiation. J Biol Chem (1996) 1.33

The metabolic syndrome--a neuroendocrine disorder? Br J Nutr (2000) 1.33

Subcutaneous abdominal preadipocyte differentiation in vitro inversely correlates with central obesity. Am J Physiol Endocrinol Metab (2004) 1.32

Efficacy of troglitazone on body fat distribution in type 2 diabetes. Diabetes Care (2000) 1.29

Leptin induction of UCP1 gene expression is dependent on sympathetic innervation. Am J Physiol (1998) 1.22

Direct effects of leptin on brown and white adipose tissue. J Clin Invest (1997) 1.22

Studies of regional adipose transplantation reveal a unique and beneficial interaction between subcutaneous adipose tissue and the intra-abdominal compartment. Diabetologia (2008) 1.20

Sympathetic but not sensory denervation stimulates white adipocyte proliferation. Am J Physiol Regul Integr Comp Physiol (2006) 1.19

Sex differences in regional distribution of fat cell size and lipoprotein lipase activity in morbidly obese patients. Int J Obes (1987) 1.19

Local sympathetic denervation of white adipose tissue in rats induces preadipocyte proliferation without noticeable changes in metabolism. Endocrinology (1993) 1.19

Lipolysis in human adipocytes, effects of cell size, age and of regional differences. Horm Metab Res Suppl (1988) 1.13

Effects of fat depot site on differentiation-dependent gene expression in rat preadipocytes. Int J Obes Relat Metab Disord (1996) 1.13

Effects of age, sex, and clinical conditions on adipose tissue cellularity in man. Metabolism (1974) 1.13

Adipocyte-selective reduction of the leptin receptors induced by antisense RNA leads to increased adiposity, dyslipidemia, and insulin resistance. J Biol Chem (2003) 1.12

Cellularity in different regions of adipose tissue in young men and women. Metabolism (1972) 1.10

Regulation of adiponectin and leptin gene expression in white and brown adipose tissues: influence of beta3-adrenergic agonists, retinoic acid, leptin and fasting. Biochim Biophys Acta (2002) 1.10

Transplantation of adipose tissue lacking leptin is unable to reverse the metabolic abnormalities associated with lipoatrophy. Diabetes (2002) 1.09

Fat depot origin affects fatty acid handling in cultured rat and human preadipocytes. Am J Physiol Endocrinol Metab (2001) 1.09

Adipose tissue transplantation protects ob/ob mice from obesity, normalizes insulin sensitivity and restores fertility. J Endocrinol (2005) 1.07

Effects of age and anatomic site on preadipocyte number in rat fat depots. J Gerontol (1994) 1.06

Differential proteomics of omental and subcutaneous adipose tissue reflects their unalike biochemical and metabolic properties. J Proteome Res (2009) 1.06

Leptin gene expression increases with age independent of increasing adiposity in rats. Diabetes (1997) 1.05

In vitro lipolytic effect of leptin on mouse adipocytes: evidence for a possible autocrine/paracrine role of leptin. Biochem Biophys Res Commun (1997) 1.04

The effects of androgens and estrogens on preadipocyte proliferation in human adipose tissue: influence of gender and site. J Clin Endocrinol Metab (2001) 1.04

Preadipocyte function and aging: links between age-related changes in cell dynamics and altered fat tissue function. J Am Geriatr Soc (1997) 1.04