Epigenetic regulation of oligodendrocyte identity.

PubWeight™: 1.36‹?› | Rank: Top 10%

🔗 View Article (PMC 2849857)

Published in Trends Neurosci on March 12, 2010

Authors

Jia Liu1, Patrizia Casaccia

Author Affiliations

1: Department of Neuroscience and Genetics and Genomics, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA.

Articles citing this

Epigenetic mechanisms in neurological disease. Nat Med (2012) 1.74

Patterns of microRNA expression in normal and early Alzheimer's disease human temporal cortex: white matter versus gray matter. Acta Neuropathol (2010) 1.71

Epigenetic perspective on the developmental effects of bisphenol A. Brain Behav Immun (2011) 1.43

Diffuse intrinsic pontine glioma: poised for progress. Front Oncol (2012) 1.41

Glial development: the crossroads of regeneration and repair in the CNS. Neuron (2014) 1.12

Identification of a gene regulatory network necessary for the initiation of oligodendrocyte differentiation. PLoS One (2011) 1.11

DNA methylation and histone modifications regulate de novo shoot regeneration in Arabidopsis by modulating WUSCHEL expression and auxin signaling. PLoS Genet (2011) 1.11

Molecular mechanisms of neonatal brain injury. Neurol Res Int (2012) 1.07

The Long and the Short of it: Gene and Environment Interactions During Early Cortical Development and Consequences for Long-Term Neurological Disease. Front Psychiatry (2012) 0.97

Dynamic changes in Ezh2 gene occupancy underlie its involvement in neural stem cell self-renewal and differentiation towards oligodendrocytes. PLoS One (2012) 0.96

Epigenetic mechanisms in multiple sclerosis: implications for pathogenesis and treatment. Lancet Neurol (2013) 0.96

Changed histone acetylation patterns in normal-appearing white matter and early multiple sclerosis lesions. J Neurosci (2011) 0.95

The nucleosome remodeling and deacetylase chromatin remodeling (NuRD) complex is required for peripheral nerve myelination. J Neurosci (2012) 0.95

MicroRNAs and Multiple Sclerosis. Autoimmune Dis (2010) 0.94

Mechanisms of oligodendrocyte regeneration from ventricular-subventricular zone-derived progenitor cells in white matter diseases. Front Cell Neurosci (2013) 0.94

The QKI-5 and QKI-6 RNA binding proteins regulate the expression of microRNA 7 in glial cells. Mol Cell Biol (2013) 0.93

Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury. J Neuroinflammation (2012) 0.92

Regulating critical period plasticity: insight from the visual system to fear circuitry for therapeutic interventions. Front Psychiatry (2013) 0.90

Polydendrocytes in development and myelin repair. Neurosci Bull (2013) 0.90

Mechanostimulation Promotes Nuclear and Epigenetic Changes in Oligodendrocytes. J Neurosci (2016) 0.89

Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division. Nat Neurosci (2014) 0.88

Aspartoacylase deficiency affects early postnatal development of oligodendrocytes and myelination. Neurobiol Dis (2010) 0.87

Extensive aspartoacylase expression in the rat central nervous system. Glia (2011) 0.87

Oligodendrogenesis in the normal and pathological central nervous system. Front Neurosci (2014) 0.87

Targeting specific HATs for neurodegenerative disease treatment: translating basic biology to therapeutic possibilities. Front Cell Neurosci (2013) 0.86

c-Myc-dependent transcriptional regulation of cell cycle and nucleosomal histones during oligodendrocyte differentiation. Neuroscience (2014) 0.86

Epigenetic modifiers are necessary but not sufficient for reprogramming non-myelinating cells into myelin gene-expressing cells. PLoS One (2010) 0.86

Nitric oxide: perspectives and emerging studies of a well known cytotoxin. Int J Mol Sci (2010) 0.84

The RE1 binding protein REST regulates oligodendrocyte differentiation. J Neurosci (2011) 0.84

Birth size and brain function 75 years later. Pediatrics (2014) 0.83

Epigenetic setting and reprogramming for neural cell fate determination and differentiation. Philos Trans R Soc Lond B Biol Sci (2014) 0.82

Epigenetics of neural repair following spinal cord injury. Neurotherapeutics (2013) 0.81

Differential Effects of Isoxazole-9 on Neural Stem/Progenitor Cells, Oligodendrocyte Precursor Cells, and Endothelial Progenitor Cells. PLoS One (2015) 0.81

Interplay between transcriptional control and chromatin regulation in the oligodendrocyte lineage. Glia (2015) 0.80

Multiple system atrophy: genetic or epigenetic? Exp Neurobiol (2014) 0.80

Epigenetics in NG2 glia cells. Brain Res (2015) 0.79

The Autotaxin-Lysophosphatidic Acid Axis Modulates Histone Acetylation and Gene Expression during Oligodendrocyte Differentiation. J Neurosci (2015) 0.78

The Epigenetic Link between Prenatal Adverse Environments and Neurodevelopmental Disorders. Genes (Basel) (2017) 0.76

Anti-TANKyrase weapons promote myelination. Nat Neurosci (2011) 0.76

Regulatory modules function in a non-autonomous manner to control transcription of the mbp gene. Nucleic Acids Res (2010) 0.76

Epigenetic control of oligodendrocyte development: adding new players to old keepers. Curr Opin Neurobiol (2016) 0.76

Epigenetic Modulation of Human Induced Pluripotent Stem Cell Differentiation to Oligodendrocytes. Int J Mol Sci (2016) 0.76

Sodium Butyrate, a Histone Deacetylase Inhibitor, Exhibits Neuroprotective/Neurogenic Effects in a Rat Model of Neonatal Hypoxia-Ischemia. Mol Neurobiol (2016) 0.76

Polycomb controls gliogenesis by regulating the transient expression of the Gcm/Glide fate determinant. PLoS Genet (2012) 0.76

A new role for the P2Y-like GPR17 receptor in the modulation of multipotency of oligodendrocyte precursor cells in vitro. Purinergic Signal (2016) 0.75

Mechanical Strain Promotes Oligodendrocyte Differentiation by Global Changes of Gene Expression. Front Cell Neurosci (2017) 0.75

Unwrapping Neurotrophic Cytokines and Histone Modification. Cell Mol Neurobiol (2016) 0.75

Leukemia/lymphoma-related factor (LRF) exhibits stage- and context-dependent transcriptional controls in the oligodendrocyte lineage and modulates remyelination. J Neurosci Res (2017) 0.75

Articles cited by this

(truncated to the top 100)

MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature (2007) 65.18

Chromatin modifications and their function. Cell (2007) 55.98

A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell (2006) 48.80

Core transcriptional regulatory circuitry in human embryonic stem cells. Cell (2005) 34.93

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature (2007) 28.24

Control of developmental regulators by Polycomb in human embryonic stem cells. Cell (2006) 28.21

The role of chromatin during transcription. Cell (2007) 26.48

Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature (2006) 25.90

Dissecting direct reprogramming through integrative genomic analysis. Nature (2008) 16.47

Stability and flexibility of epigenetic gene regulation in mammalian development. Nature (2007) 14.57

Embryonic stem cell-specific MicroRNAs. Dev Cell (2003) 13.05

Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell (2002) 13.05

Role for DNA methylation in genomic imprinting. Nature (1993) 12.65

Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell (2002) 12.28

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol (2008) 10.97

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat Biotechnol (2008) 10.29

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature (2008) 9.83

Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark. Mol Cell (2007) 9.73

Role of histone H2A ubiquitination in Polycomb silencing. Nature (2004) 9.48

Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annu Rev Biochem (2006) 8.66

REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell (2005) 8.65

MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell (2009) 8.14

Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell (2008) 7.79

Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol Cell (2008) 7.68

Polycomb silencing mechanisms and the management of genomic programmes. Nat Rev Genet (2007) 7.61

Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat Biotechnol (2009) 7.59

Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells. Cell Stem Cell (2007) 7.05

Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells (2005) 6.72

Reciprocal actions of REST and a microRNA promote neuronal identity. Proc Natl Acad Sci U S A (2006) 5.78

Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells (2006) 5.68

Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell (2002) 5.64

The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. Nature (2006) 5.51

Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell (2008) 5.40

PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice. Nat Neurosci (2008) 5.25

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease. Genes Dev (2008) 5.25

Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science (2009) 5.24

Origin of oligodendrocytes in the subventricular zone of the adult brain. J Neurosci (2006) 4.90

The glial identity of neural stem cells. Nat Neurosci (2003) 4.72

Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. Science (1999) 4.69

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Mol Cell Biol (2008) 4.56

Regulation of neuronal traits by a novel transcriptional complex. Neuron (2001) 4.02

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells. Nat Struct Mol Biol (2008) 3.98

Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells. Mol Cell Biol (2004) 3.76

Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity. Nat Rev Neurosci (2009) 3.72

Histone lysine demethylases: emerging roles in development, physiology and disease. Nat Rev Genet (2007) 3.65

A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation. J Biol Chem (2002) 3.50

X-chromosome inactivation in mammals. Annu Rev Genet (1997) 3.50

Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain. Cell (2006) 3.42

Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat Neurosci (2008) 3.24

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci (2009) 3.18

Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal. Nat Rev Mol Cell Biol (2009) 3.12

Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons. J Cell Biol (2003) 3.06

Histone deacetylases: unique players in shaping the epigenetic histone code. Ann N Y Acad Sci (2003) 3.05

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes Dev (2009) 2.96

Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytes. J Neurosci (2008) 2.95

A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development. Development (1994) 2.83

Mechanisms involved in the regulation of histone lysine demethylases. Curr Opin Cell Biol (2008) 2.81

Unsafe SETs: histone lysine methyltransferases and cancer. Trends Biochem Sci (2002) 2.80

PR-Set7-dependent methylation of histone H4 Lys 20 functions in repression of gene expression and is essential for mitosis. Genes Dev (2005) 2.51

Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factor. Development (2001) 2.43

The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron (2007) 2.38

N-CoR controls differentiation of neural stem cells into astrocytes. Nature (2002) 2.36

Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol (2005) 2.34

Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Mol Cell (2009) 2.27

Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation. Development (2004) 2.21

Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell (2009) 2.18

Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition. Neuron (2009) 2.16

Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex. Mol Cancer (2006) 2.09

Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain. Neuron (2005) 2.03

Mechanisms of ATP dependent chromatin remodeling. Mutat Res (2007) 1.94

Developmental roles of the histone lysine demethylases. Development (2009) 1.92

Epigenetic mechanisms in mammals. Cell Mol Life Sci (2009) 1.82

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell (2006) 1.79

Spatial and temporal specification of neural fates by transcription factor codes. Development (2007) 1.76

Neural stem cell self-renewal. Crit Rev Oncol Hematol (2007) 1.76

Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells. Genes Dev (2004) 1.63

Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulin. J Neurosci (2007) 1.60

Olig1 and Sox10 interact synergistically to drive myelin basic protein transcription in oligodendrocytes. J Neurosci (2007) 1.58

Trithorax-group protein ASH1 methylates histone H3 lysine 36. Gene (2007) 1.56

Myt1 family recruits histone deacetylase to regulate neural transcription. J Neurochem (2005) 1.54

MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses cyclin A2 expression, and promotes myogenic differentiation. Proc Natl Acad Sci U S A (2009) 1.54

Epigenetic principles and mechanisms underlying nervous system functions in health and disease. Prog Neurobiol (2008) 1.53

Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS. Mech Dev (2005) 1.53

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat Struct Mol Biol (2008) 1.51

A molecular insight of Hes5-dependent inhibition of myelin gene expression: old partners and new players. EMBO J (2006) 1.49

A matter of identity: transcriptional control in oligodendrocytes. J Mol Neurosci (2007) 1.47

miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination. Dis Model Mech (2009) 1.46

An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation. Development (2006) 1.43

SoxE function in vertebrate nervous system development. Int J Biochem Cell Biol (2009) 1.38

Histone H3K4 demethylases are essential in development and differentiation. Biochem Cell Biol (2007) 1.34

The multiple facets of histone H4-lysine 20 methylation. Biochem Cell Biol (2009) 1.28

Differentiation of neural stem cells into oligodendrocytes: involvement of the polycomb group protein Ezh2. Stem Cells (2008) 1.26

Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells. Proc Natl Acad Sci U S A (2007) 1.26

Myelin transcription factor 1 (Myt1) modulates the proliferation and differentiation of oligodendrocyte lineage cells. Mol Cell Neurosci (2004) 1.26

The glial or neuronal fate choice of oligodendrocyte progenitors is modulated by their ability to acquire an epigenetic memory. J Neurosci (2007) 1.22

Multiple roles of Id4 in developmental myelination: predicted outcomes and unexpected findings. Glia (2006) 1.21

The Yin and Yang of Sox proteins: Activation and repression in development and disease. J Neurosci Res (2009) 1.20

Ascl1 is required for oligodendrocyte development in the spinal cord. Development (2008) 1.20

Articles by these authors

Impaired adult myelination in the prefrontal cortex of socially isolated mice. Nat Neurosci (2012) 2.20

HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage. Nat Neurosci (2009) 1.67

Two-tier transcriptional control of oligodendrocyte differentiation. Curr Opin Neurobiol (2009) 1.17

Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination. Nat Neurosci (2010) 1.16

HDAC inhibitors and neurodegeneration: at the edge between protection and damage. Pharmacol Res (2010) 1.15

Identification of a gene regulatory network necessary for the initiation of oligodendrocyte differentiation. PLoS One (2011) 1.11

Maternal cannabis use alters ventral striatal dopamine D2 gene regulation in the offspring. Biol Psychiatry (2011) 1.07

Cell-context specific role of the E2F/Rb pathway in development and disease. Glia (2010) 1.04

Differential modulation of the oligodendrocyte transcriptome by sonic hedgehog and bone morphogenetic protein 4 via opposing effects on histone acetylation. J Neurosci (2012) 0.98

Epigenetic mechanisms in multiple sclerosis: implications for pathogenesis and treatment. Lancet Neurol (2013) 0.96

Changed histone acetylation patterns in normal-appearing white matter and early multiple sclerosis lesions. J Neurosci (2011) 0.95

Primary brain tumors, neural stem cell, and brain tumor cancer cells: where is the link? Neuropharmacology (2010) 0.93

E2F1 coregulates cell cycle genes and chromatin components during the transition of oligodendrocyte progenitors from proliferation to differentiation. J Neurosci (2014) 0.92

Gene expression abnormalities and oligodendrocyte deficits in the internal capsule in schizophrenia. Schizophr Res (2010) 0.91

Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia. J Neurosci (2013) 0.90

Roles of p53 and p27(Kip1) in the regulation of neurogenesis in the murine adult subventricular zone. Eur J Neurosci (2011) 0.88

Aspartoacylase deficiency affects early postnatal development of oligodendrocytes and myelination. Neurobiol Dis (2010) 0.87

Axonal damage in multiple sclerosis. Mt Sinai J Med (2011) 0.87

Shaping the oligodendrocyte identity by epigenetic control. Epigenetics (2010) 0.86

Epigenetic modifiers are necessary but not sufficient for reprogramming non-myelinating cells into myelin gene-expressing cells. PLoS One (2010) 0.86

HDAC1 in axonal degeneration: A matter of subcellular localization. Cell Cycle (2010) 0.84

Progressive multiple sclerosis and gray matter pathology: an MRI perspective. Mt Sinai J Med (2011) 0.81

Defining the chromatin landscape in demyelinating disorders. Neurobiol Dis (2009) 0.77

An integrated approach to design novel therapeutic interventions for demyelinating disorders. Eur J Neurosci (2012) 0.75