Published in Angew Chem Int Ed Engl on January 01, 2009
Protein microarrays: novel developments and applications. Pharm Res (2010) 1.00
Radiation-induced biomarkers for the detection and assessment of absorbed radiation doses. J Pharm Bioallied Sci (2010) 0.89
Formation of carbohydrate-functionalised polystyrene and glass slides and their analysis by MALDI-TOF MS. Beilstein J Org Chem (2012) 0.82
Immobilization of Ferrocene-Modified SNAP-Fusion Proteins. Int J Mol Sci (2013) 0.79
His-tags lighten up and lose their inhibitions. Proc Natl Acad Sci U S A (2010) 0.78
Diagnostic value of protein chips constructed by lung-cancer-associated markers selected by the T7 phage display library. Thorac Cancer (2015) 0.76
Nanostructured microfluidic digestion system for rapid high-performance proteolysis. Lab Chip (2015) 0.75
Utilization of cytogenetic biomarkers as a tool for assessment of radiation injury and evaluation of radiomodulatory effects of various medicinal plants - a review. Drug Des Devel Ther (2015) 0.75
Controlling Protein Surface Orientation by Strategic Placement of Oligo-Histidine Tags. ACS Nano (2017) 0.75
An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science (2005) 5.99
Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling. Nature (2013) 5.04
A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nat Cell Biol (2009) 3.44
The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins. Cell (2010) 2.72
About supramolecular assemblies of pi-conjugated systems. Chem Rev (2005) 2.64
Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation. Nat Chem Biol (2010) 2.39
Small-molecule inhibition of APT1 affects Ras localization and signaling. Nat Chem Biol (2010) 2.37
Charting biologically relevant chemical space: a structural classification of natural products (SCONP). Proc Natl Acad Sci U S A (2005) 2.35
A crowdsourcing evaluation of the NIH chemical probes. Nat Chem Biol (2009) 2.29
The scaffold tree--visualization of the scaffold universe by hierarchical scaffold classification. J Chem Inf Model (2007) 2.04
From protein domains to drug candidates-natural products as guiding principles in the design and synthesis of compound libraries. Angew Chem Int Ed Engl (2002) 2.03
Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo. Nat Chem Biol (2011) 2.00
Therapeutic intervention based on protein prenylation and associated modifications. Nat Chem Biol (2006) 1.96
Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proc Natl Acad Sci U S A (2006) 1.96
Rational design of DNA nanoarchitectures. Angew Chem Int Ed Engl (2006) 1.88
Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase. Science (2003) 1.80
Inhibitors of protein tyrosine phosphatases: next-generation drugs? Angew Chem Int Ed Engl (2005) 1.73
Gradient-driven motion of multivalent ligand molecules along a surface functionalized with multiple receptors. Nat Chem (2011) 1.70
Interactive exploration of chemical space with Scaffold Hunter. Nat Chem Biol (2009) 1.55
Chemical strategies for generating protein biochips. Angew Chem Int Ed Engl (2008) 1.55
Analysis of the eukaryotic prenylome by isoprenoid affinity tagging. Nat Chem Biol (2009) 1.50
Natural product-derived modulators of cell cycle progression and viral entry by enantioselective oxa Diels-Alder reactions on the solid phase. Chem Biol (2007) 1.43
Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis. Proc Natl Acad Sci U S A (2012) 1.41
Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase. Mol Cell (2003) 1.37
Visualizing association of N-ras in lipid microdomains: influence of domain structure and interfacial adsorption. J Am Chem Soc (2006) 1.35
Beta-lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana. Nat Chem Biol (2008) 1.30
Target identification for small bioactive molecules: finding the needle in the haystack. Angew Chem Int Ed Engl (2013) 1.28
Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators. Proc Natl Acad Sci U S A (2007) 1.26
Sensitivity by combination: immuno-PCR and related technologies. Analyst (2008) 1.25
Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes. Nat Chem Biol (2010) 1.24
Performance of antibody microarrays fabricated by either DNA-directed immobilization, direct spotting, or streptavidin-biotin attachment: a comparative study. Anal Biochem (2004) 1.24
Synthesis of natural product inspired compound collections. Angew Chem Int Ed Engl (2009) 1.23
DNA microarrays with PAMAM dendritic linker systems. Nucleic Acids Res (2002) 1.22
A framework for identification of actionable cancer genome dependencies in small cell lung cancer. Proc Natl Acad Sci U S A (2012) 1.21
The Pictet-Spengler reaction in nature and in organic chemistry. Angew Chem Int Ed Engl (2011) 1.20
Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products. Nat Chem (2010) 1.19
Biology-oriented synthesis. Angew Chem Int Ed Engl (2011) 1.18
Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor. Int J Cancer (2012) 1.18
Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem (2012) 1.17
Staudinger ligation: a new immobilization strategy for the preparation of small-molecule arrays. Angew Chem Int Ed Engl (2003) 1.17
Compound library development guided by protein structure similarity clustering and natural product structure. Proc Natl Acad Sci U S A (2004) 1.17
The therapeutic potential of phosphatase inhibitors. Curr Opin Chem Biol (2009) 1.16
Identification and specificity profiling of protein prenyltransferase inhibitors using new fluorescent phosphoisoprenoids. J Am Chem Soc (2006) 1.15
Exploiting the substrate tolerance of farnesyltransferase for site-selective protein derivatization. Chembiochem (2007) 1.15
(-)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels. Angew Chem Int Ed Engl (2015) 1.14
Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling. EMBO J (2006) 1.14
Charting, navigating, and populating natural product chemical space for drug discovery. J Med Chem (2012) 1.14
Development of tau aggregation inhibitors for Alzheimer's disease. Angew Chem Int Ed Engl (2009) 1.13
18F-labeling of peptides by means of an organosilicon-based fluoride acceptor. Angew Chem Int Ed Engl (2006) 1.13
N-Ras forms dimers at POPC membranes. Biophys J (2012) 1.13
Orthogonal protein decoration of DNA origami. Angew Chem Int Ed Engl (2010) 1.13
Membrane insertion of a lipidated ras peptide studied by FTIR, solid-state NMR, and neutron diffraction spectroscopy. J Am Chem Soc (2003) 1.12
Identification of acyl protein thioesterases 1 and 2 as the cellular targets of the Ras-signaling modulators palmostatin B and M. Angew Chem Int Ed Engl (2011) 1.11
Bioactivity-guided mapping and navigation of chemical space. Nat Chem Biol (2009) 1.11
Rhodanine-based tau aggregation inhibitors in cell models of tauopathy. Angew Chem Int Ed Engl (2007) 1.11
On the generation of free radical species from quantum dots. Small (2005) 1.10
Diels-Alder ligation and surface immobilization of proteins. Angew Chem Int Ed Engl (2005) 1.10
Discovery of a new class of inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B by biology-oriented synthesis. Angew Chem Int Ed Engl (2008) 1.09
Small-molecule inhibitors of islet amyloid polypeptide fibril formation. Angew Chem Int Ed Engl (2008) 1.09
Brunsvicamides A-C: sponge-related cyanobacterial peptides with Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory activity. J Med Chem (2006) 1.09
Influence of the lipidation motif on the partitioning and association of N-Ras in model membrane subdomains. J Am Chem Soc (2009) 1.09
DNA origami: the art of folding DNA. Angew Chem Int Ed Engl (2011) 1.08
Membrane-mediated induction and sorting of K-Ras microdomain signaling platforms. J Am Chem Soc (2010) 1.08
Inhibiting the palmitoylation/depalmitoylation cycle selectively reduces the growth of hematopoietic cells expressing oncogenic Nras. Blood (2011) 1.08
Functionalization of DNA nanostructures with proteins. Chem Soc Rev (2011) 1.08
Interlaboratory round robin on cantilever calibration for AFM force spectroscopy. Ultramicroscopy (2011) 1.08
Bioactivity-guided navigation of chemical space. Acc Chem Res (2010) 1.07
Synthesis of the Rheb and K-Ras4B GTPases. Angew Chem Int Ed Engl (2010) 1.07
ATP competitive inhibitors of D-alanine-D-alanine ligase based on protein kinase inhibitor scaffolds. Bioorg Med Chem (2008) 1.07
Asymmetric solid-phase synthesis of 6,6-spiroketals. Angew Chem Int Ed Engl (2004) 1.06
The cholesterol membrane anchor of the Hedgehog protein confers stable membrane association to lipid-modified proteins. Proc Natl Acad Sci U S A (2004) 1.05
The lipidated membrane anchor of full length N-Ras protein shows an extensive dynamics as revealed by solid-state NMR spectroscopy. J Am Chem Soc (2006) 1.03
DNA-mediated assembly of cytochrome P450 BM3 subdomains. J Am Chem Soc (2011) 1.03
3-Substituted indolizine-1-carbonitrile derivatives as phosphatase inhibitors. Bioorg Med Chem Lett (2005) 1.02
Chemical biology of protein lipidation: semi-synthesis and structure elucidation of prenylated RabGTPases. Org Biomol Chem (2005) 1.02
Membrane binding of lipidated Ras peptides and proteins--the structural point of view. Biochim Biophys Acta (2008) 1.02
Revealing conformational substates of lipidated N-Ras protein by pressure modulation. Proc Natl Acad Sci U S A (2011) 1.02
Flexibility of ras lipid modifications studied by 2H solid-state NMR and molecular dynamics simulations. Biophys J (2007) 1.01
Identification of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase B. Angew Chem Int Ed Engl (2010) 1.01
Synthesis and structure-activity correlation of natural-product inspired cyclodepsipeptides stabilizing F-actin. J Am Chem Soc (2010) 1.01
Lipid modifications of a Ras peptide exhibit altered packing and mobility versus host membrane as detected by 2H solid-state NMR. J Am Chem Soc (2005) 1.00
Site-selective protein immobilization by Staudinger ligation. Angew Chem Int Ed Engl (2006) 1.00
Oriented immobilization of farnesylated proteins by the thiol-ene reaction. Angew Chem Int Ed Engl (2010) 1.00
Natural product guided compound library development. Curr Med Chem (2002) 0.99
Magnetic deformation of self-assembled sexithiophene spherical nanocapsules. J Am Chem Soc (2005) 0.99
Lipidated ras and rab peptides and proteins--synthesis, structure, and function. Angew Chem Int Ed Engl (2006) 0.99
Magneto immuno-PCR: a novel immunoassay based on biogenic magnetosome nanoparticles. Biochem Biophys Res Commun (2007) 0.99
Raft protein clustering alters N-Ras membrane interactions and activation pattern. Mol Cell Biol (2011) 0.99
The core structures of roseophilin and the prodigiosin alkaloids define a new class of protein tyrosine phosphatase inhibitors. Chembiochem (2004) 0.97
Synthesis and biological evaluation of an indomethacin library reveals a new class of angiogenesis-related kinase inhibitors. Angew Chem Int Ed Engl (2004) 0.97
DDI-microFIA--A readily configurable microarray-fluorescence immunoassay based on DNA-directed immobilization of proteins. Chembiochem (2004) 0.97
Partitioning of dual-lipidated peptides into membrane microdomains: lipid sorting vs peptide aggregation. J Am Chem Soc (2004) 0.97
Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation. EMBO J (2008) 0.97
Natural product-inspired cascade synthesis yields modulators of centrosome integrity. Nat Chem Biol (2011) 0.97
Synthesis and structure-activity correlation of a brunsvicamide-inspired cyclopeptide collection. Chembiochem (2009) 0.97