Published in Am J Physiol Cell Physiol on September 30, 2009
Role for the actomyosin complex in regulated exocytosis revealed by intravital microscopy. Proc Natl Acad Sci U S A (2011) 1.74
Intravital microscopy: a novel tool to study cell biology in living animals. Histochem Cell Biol (2010) 1.51
Multiple roles for the actin cytoskeleton during regulated exocytosis. Cell Mol Life Sci (2012) 1.35
Imaging cell biology in live animals: ready for prime time. J Cell Biol (2013) 1.35
From seeing to believing: labelling strategies for in vivo cell-tracking experiments. Interface Focus (2013) 1.17
Intravital microscopy as a tool to study drug delivery in preclinical studies. Adv Drug Deliv Rev (2010) 1.17
Intravital microscopy: a practical guide on imaging intracellular structures in live animals. Bioarchitecture (2012) 1.03
Gene delivery in salivary glands: from the bench to the clinic. Biochim Biophys Acta (2011) 0.98
Regulated exocytosis: novel insights from intravital microscopy. Traffic (2012) 0.98
Intravital microscopy to image membrane trafficking in live rats. Methods Mol Biol (2013) 0.95
Nanoparticle-mediated gene silencing confers radioprotection to salivary glands in vivo. Mol Ther (2013) 0.90
Human parathyroid hormone is secreted primarily into the bloodstream after rat parotid gland gene transfer. Hum Gene Ther (2011) 0.86
Homeostasis of the apical plasma membrane during regulated exocytosis in the salivary glands of live rodents. Bioarchitecture (2011) 0.85
Intravital microscopy for imaging subcellular structures in live mice expressing fluorescent proteins. J Vis Exp (2013) 0.85
Plasmid DNA is internalized from the apical plasma membrane of the salivary gland epithelium in live animals. Histochem Cell Biol (2012) 0.85
Linking differences in membrane tension with the requirement for a contractile actomyosin scaffold during exocytosis in salivary glands. Commun Integr Biol (2012) 0.83
Imaging the dynamics of endocytosis in live mammalian tissues. Cold Spring Harb Perspect Biol (2014) 0.81
Viral gene transfer to developing mouse salivary glands. J Dent Res (2011) 0.81
In vivo veritas: the power of in situ manipulation of cells in a living animal. Focus on "Expression of plasmid DNA in the salivary gland epithelium: novel approaches to study dynamic cellular processes in live animals". Am J Physiol Cell Physiol (2009) 0.81
Intravital Microscopy Reveals Differences in the Kinetics of Endocytic Pathways between Cell Cultures and Live Animals. Cells (2012) 0.80
Imaging membrane remodeling during regulated exocytosis in live mice. Exp Cell Res (2015) 0.77
Polyethylenimine-mediated expression of transgenes in the acinar cells of rats salivary glands in vivo. Front Cell Dev Biol (2015) 0.76
A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications. Nat Biotechnol (2002) 22.05
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci U S A (1996) 9.15
Biochemical studies on adenovirus multiplication. IV. Isolation, purification, and chemical analysis of adenovirus. Virology (1963) 6.75
Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses. Neuron (2006) 5.70
Clathrin-coated vesicle formation and protein sorting: an integrated process. Annu Rev Biochem (1997) 5.58
Adenovirus DNA. I. Molecular weight and conformation. Proc Natl Acad Sci U S A (1967) 5.55
Functional studies of the kidney of living animals using multicolor two-photon microscopy. Am J Physiol Cell Physiol (2002) 3.09
Regulation of fluid and electrolyte secretion in salivary gland acinar cells. Annu Rev Physiol (2005) 2.94
CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo. J Exp Med (2007) 2.81
Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis. Nature (2009) 2.79
Vesicular proteins exocytosed and subsequently retrieved by compensatory endocytosis are nonidentical. Nat Neurosci (2006) 2.40
Luminal membrane retrieved after exocytosis reaches most golgi cisternae in secretory cells. Proc Natl Acad Sci U S A (1977) 2.33
Molecular basis of the inflammatory response to adenovirus vectors. Gene Ther (2003) 2.29
Multi-photon excitation microscopy in intact animals. J Microsc (2006) 1.60
Imaging transgene expression in live animals. Mol Ther (2001) 1.43
Direct in vivo adenovirus-mediated gene transfer to salivary glands. Am J Physiol (1994) 1.40
Parotid secretory granules: crossroads of secretory pathways and protein storage. J Dent Res (2005) 1.39
Intravital two-photon microscopy for studying the uptake and trafficking of fluorescently conjugated molecules in live rodents. Traffic (2008) 1.36
Alteration of tight junctional permeability in the rat parotid gland after isoproterenol stimulation. J Cell Biol (1984) 1.26
The rat submaxillary salivary gland. A correlative study by light and electron microscopy. J Morphol (1965) 1.23
Immune responses to adeno-associated virus and its recombinant vectors. Gene Ther (2003) 1.18
Nonviral approaches for targeted delivery of plasmid DNA and oligonucleotide. J Pharm Sci (2008) 1.13
Mammalian genome targeting using site-specific recombinases. Front Biosci (2006) 1.12
Quantifying endocytosis in vivo using intravital two-photon microscopy. Methods Mol Biol (2008) 1.10
Mechanism of enhancement of DNA expression consequent to cointernalization of a replication-deficient adenovirus and unmodified plasmid DNA. J Virol (1994) 1.09
Differential sorting of human parathyroid hormone after transduction of mouse and rat salivary glands. Hum Gene Ther (2008) 1.04
Characterization of epithelial elements in human major salivary glands by functional markers: localization of amylase, lactoferrin, lysozyme, secretory component, and secretory immunoglobulins by paired immunofluorescence staining. J Histochem Cytochem (1982) 1.00
Protein secretion by rat parotid acinar cells. Pathways and regulation. Ann N Y Acad Sci (1998) 1.00
The endocrine secretion of human insulin and growth hormone by exocrine glands of the gastrointestinal tract. Nat Biotechnol (1997) 0.99
Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction. Biochim Biophys Acta (2005) 0.99
Gene transfer mediated by different viral vectors following direct cannulation of mouse submandibular salivary glands. Eur J Oral Sci (2002) 0.98
Degranulation of rat salivary glands following treatment with receptor-selective agonists. Clin Exp Pharmacol Physiol (1995) 0.97
Cationic liposome-mediated gene transfer to rat salivary epithelial cells in vitro and in vivo. J Gene Med (2001) 0.97
Exocytosis in human salivary glands visualized by high-resolution scanning electron microscopy. Cell Tissue Res (1998) 0.96
Adenoviral-mediated gene transfer to mouse salivary glands. J Dent Res (2000) 0.93
A primary culture of parotid acinar cells retaining capacity for agonists-induced amylase secretion and generation of new secretory granules. Cell Tissue Res (2005) 0.86
Enhanced systemic transgene expression after nonviral salivary gland transfection using a novel endonuclease inhibitor/DNA formulation. Gene Ther (2003) 0.85
Compensatory endocytosis in chromaffin cells. Acta Physiol (Oxf) (2007) 0.85
Sorting of growth hormone-erythropoietin fusion proteins in rat salivary glands. Biochem Biophys Res Commun (2008) 0.84
Safety of salivary gland-administered replication-deficient recombinant adenovirus in rats. J Oral Pathol Med (1998) 0.82
Sialographic damage in rat submandibular gland. Oral Surg Oral Med Oral Pathol (1985) 0.79
Zinc enhancement of nonviral salivary gland transfection. Mol Ther (2003) 0.79
Morphological and functional changes in cell junctions during secretory stimulation in the perfused rat submandibular gland. Eur J Morphol (2003) 0.78
Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes. Cancer Cell (2003) 3.42
Characterization of a nonclathrin endocytic pathway: membrane cargo and lipid requirements. Mol Biol Cell (2004) 2.99
Convergence of non-clathrin- and clathrin-derived endosomes involves Arf6 inactivation and changes in phosphoinositides. Mol Biol Cell (2003) 2.79
Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma. Nat Genet (2011) 2.60
Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery. ACS Nano (2009) 2.39
CX3CR1-dependent renal macrophage survival promotes Candida control and host survival. J Clin Invest (2013) 2.00
Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation. Genes Dev (2005) 1.92
Selective abrogation of the uPA-uPAR interaction in vivo reveals a novel role in suppression of fibrin-associated inflammation. Blood (2010) 1.82
Discovery of new cargo proteins that enter cells through clathrin-independent endocytosis. Traffic (2009) 1.78
Role for the actomyosin complex in regulated exocytosis revealed by intravital microscopy. Proc Natl Acad Sci U S A (2011) 1.74
The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor. Cancer Cell (2006) 1.63
Epithelial integrity is maintained by a matriptase-dependent proteolytic pathway. Am J Pathol (2009) 1.62
Decreased lymphangiogenesis and lymph node metastasis by mTOR inhibition in head and neck cancer. Cancer Res (2011) 1.54
Cyclooxygenase-1 is involved in the inhibition of hippocampal neurogenesis after lipopolysaccharide-induced neuroinflammation. Cell Cycle (2011) 1.54
Intravital microscopy: a novel tool to study cell biology in living animals. Histochem Cell Biol (2010) 1.51
Co-localization of the channel activating protease prostasin/(CAP1/PRSS8) with its candidate activator, matriptase. J Cell Physiol (2007) 1.51
Semaphorin 3E initiates antiangiogenic signaling through plexin D1 by regulating Arf6 and R-Ras. Mol Cell Biol (2010) 1.50
A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells. Sci Signal (2011) 1.45
Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase proteolytic activity and is phenocopied in ST14 hypomorphic mice. J Biol Chem (2007) 1.44
A role for Arf1 in mitotic Golgi disassembly, chromosome segregation, and cytokinesis. Proc Natl Acad Sci U S A (2003) 1.43
Matrix metalloproteinase-activated anthrax lethal toxin demonstrates high potency in targeting tumor vasculature. J Biol Chem (2007) 1.41
Multiple activities for Arf1 at the Golgi complex. Biochim Biophys Acta (2005) 1.41
Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma. Proc Natl Acad Sci U S A (2010) 1.38
Rapamycin prevents early onset of tumorigenesis in an oral-specific K-ras and p53 two-hit carcinogenesis model. Cancer Res (2009) 1.37
Intravital two-photon microscopy for studying the uptake and trafficking of fluorescently conjugated molecules in live rodents. Traffic (2008) 1.36
Multiple roles for the actin cytoskeleton during regulated exocytosis. Cell Mol Life Sci (2012) 1.35
Delineation of matriptase protein expression by enzymatic gene trapping suggests diverging roles in barrier function, hair formation, and squamous cell carcinogenesis. Am J Pathol (2006) 1.32
Potent inhibition and global co-localization implicate the transmembrane Kunitz-type serine protease inhibitor hepatocyte growth factor activator inhibitor-2 in the regulation of epithelial matriptase activity. J Biol Chem (2008) 1.31
Inhibition of Mammalian target of rapamycin by rapamycin causes the regression of carcinogen-induced skin tumor lesions. Clin Cancer Res (2008) 1.26
Progressive tumor formation in mice with conditional deletion of TGF-beta signaling in head and neck epithelia is associated with activation of the PI3K/Akt pathway. Cancer Res (2009) 1.24
A role for a CXCR2/phosphatidylinositol 3-kinase gamma signaling axis in acute and chronic vascular permeability. Mol Cell Biol (2009) 1.21
Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma. Mol Cancer Res (2010) 1.19
M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway. J Cell Biol (2013) 1.19
Intermolecular complementation achieves high-specificity tumor targeting by anthrax toxin. Nat Biotechnol (2005) 1.17
Intravital microscopy as a tool to study drug delivery in preclinical studies. Adv Drug Deliv Rev (2010) 1.17
Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor. Nat Med (2013) 1.13
Carcinoma-associated fibroblasts activate progesterone receptors and induce hormone independent mammary tumor growth: A role for the FGF-2/FGFR-2 axis. Int J Cancer (2008) 1.10
Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome. Nat Genet (2010) 1.09
Rapid development of salivary gland carcinomas upon conditional expression of K-ras driven by the cytokeratin 5 promoter. Am J Pathol (2006) 1.04
PTEN deficiency contributes to the development and progression of head and neck cancer. Neoplasia (2013) 1.03
Rab25 regulates invasion and metastasis in head and neck cancer. Clin Cancer Res (2013) 1.02
Myosin Vc is a molecular motor that functions in secretory granule trafficking. Mol Biol Cell (2009) 1.00
The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer. Endocr Relat Cancer (2009) 0.99
TGF-beta receptor I conditional knockout mice develop spontaneous squamous cell carcinoma. Cell Cycle (2007) 0.99
Regulated exocytosis: novel insights from intravital microscopy. Traffic (2012) 0.98
The effect of hypusine modification on the intracellular localization of eIF5A. Biochem Biophys Res Commun (2009) 0.98
Increased expression of the collagen internalization receptor uPARAP/Endo180 in the stroma of head and neck cancer. J Histochem Cytochem (2006) 0.98
Melanoregulin regulates a shedding mechanism that drives melanosome transfer from melanocytes to keratinocytes. Proc Natl Acad Sci U S A (2012) 0.97
Proliferative and nonproliferative lesions of the rat and mouse mammary, Zymbal's, preputial, and clitoral glands. Toxicol Pathol (2012) 0.96
Intravital microscopy to image membrane trafficking in live rats. Methods Mol Biol (2013) 0.95
WISP1/CCN4: a potential target for inhibiting prostate cancer growth and spread to bone. PLoS One (2013) 0.95
Reversal of antiprogestin resistance and progesterone receptor isoform ratio in acquired resistant mammary carcinomas. Breast Cancer Res Treat (2008) 0.92
Association of estrogen receptor-alpha and progesterone receptor A expression with hormonal mammary carcinogenesis: role of the host microenvironment. Breast Cancer Res (2007) 0.91
p21, p27 and p53 in estrogen and antiprogestin-induced tumor regression of experimental mouse mammary ductal carcinomas. Carcinogenesis (2002) 0.90
Female mice are more susceptible to developing inflammatory disorders due to impaired transforming growth factor beta signaling in salivary glands. Arthritis Rheum (2007) 0.90
Expression of heme oxygenase-1 in non-small cell lung cancer (NSCLC) and its correlation with clinical data. Lung Cancer (2012) 0.88
Two-photon excitation improves multifocal structured illumination microscopy in thick scattering tissue. Proc Natl Acad Sci U S A (2014) 0.87
Involvement of matrix metalloproteinase activity in hormone-induced mammary tumor regression. Am J Pathol (2006) 0.87
Natural and synthetic progestins accelerate 7,12-dimethylbenz[a]anthracene-initiated mammary tumors and increase angiogenesis in Sprague-Dawley rats. Clin Cancer Res (2006) 0.86
The cyclooxygenase-2 pathway via the PGE₂ EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination. J Neurochem (2011) 0.86
Plasmid DNA is internalized from the apical plasma membrane of the salivary gland epithelium in live animals. Histochem Cell Biol (2012) 0.85
Intravital microscopy for imaging subcellular structures in live mice expressing fluorescent proteins. J Vis Exp (2013) 0.85
Fluorescent microscopy-based assays to study the role of Rab22a in clathrin-independent endocytosis. Methods Enzymol (2005) 0.85
Homeostasis of the apical plasma membrane during regulated exocytosis in the salivary glands of live rodents. Bioarchitecture (2011) 0.85
Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters. Int J Cancer (2014) 0.84
Conditional deletion of cyclin-dependent kinase 5 in primary sensory neurons leads to atypical skin lesions. Cell Cycle (2008) 0.83
Linking differences in membrane tension with the requirement for a contractile actomyosin scaffold during exocytosis in salivary glands. Commun Integr Biol (2012) 0.83
Novel, low cost, highly effective, handmade steroid pellets for experimental studies. PLoS One (2013) 0.81
Antisense oligonucleotides targeting the progesterone receptor inhibit hormone-independent breast cancer growth in mice. Breast Cancer Res (2005) 0.81
The effectiveness of nano chemotherapeutic particles combined with mifepristone depends on the PR isoform ratio in preclinical models of breast cancer. Oncotarget (2014) 0.80
Novel aquatic silk genes Simulium (Psilozia) vittatum (Zett) Diptera: Simuliidae. Insect Biochem Mol Biol (2013) 0.79
Probing the role of the actin cytoskeleton during regulated exocytosis by intravital microscopy. Methods Mol Biol (2014) 0.78
Inhibition of mammary tumor growth by estrogens: is there a specific role for estrogen receptors alpha and beta? Breast Cancer Res Treat (2009) 0.78
Sinusoidal ephrin receptor EPHB4 controls hematopoietic progenitor cell mobilization from bone marrow. J Clin Invest (2016) 0.77
MPA-induced gene expression and stromal and parenchymal gene expression profiles in luminal murine mammary carcinomas with different hormonal requirements. Breast Cancer Res Treat (2010) 0.77
Targeting progesterone receptors in breast cancer. Vitam Horm (2013) 0.76
Mifepristone inhibits MPA-and FGF2-induced mammary tumor growth but not FGF2-induced mammary hyperplasia. Medicina (B Aires) (2010) 0.76
Endosomes derived from clathrin-independent endocytosis serve as precursors for endothelial lumen formation. PLoS One (2013) 0.75
EMR-Based Intervention Improves Lead Screening at an Urban Family Medicine Practice. Fam Med (2016) 0.75
Isolation of a stromal cell line from an early passage of a mouse mammary tumor line: a model for stromal parenchymal interactions. J Cell Physiol (2005) 0.75
Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β. Mol Cell (2016) 0.75