Budding yeast Dbf4 sequences required for Cdc7 kinase activation and identification of a functional relationship between the Dbf4 and Rev1 BRCT domains.

PubWeight™: 0.87‹?›

🔗 View Article (PMC 2787420)

Published in Genetics on October 12, 2009

Authors

Victoria Harkins1, Carrie Gabrielse, Louise Haste, Michael Weinreich

Author Affiliations

1: Laboratory of Chromosome Replication, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

Articles cited by this

A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. FASEB J (1997) 15.10

DNA replication in eukaryotic cells. Annu Rev Biochem (2001) 13.39

BRCA1 protein products ... Functional motifs... Nat Genet (1996) 11.50

Multiple sequence alignment using ClustalW and ClustalX. Curr Protoc Bioinformatics (2002) 9.86

Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Annu Rev Biochem (2005) 8.13

DNA recognition by Cys2His2 zinc finger proteins. Annu Rev Biophys Biomol Struct (2000) 6.61

GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nat Cell Biol (2006) 6.36

Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. Proc Natl Acad Sci U S A (2006) 5.66

UV mutagenesis in radiation-sensitive strains of yeast. Genetics (1976) 3.96

Structural classification of zinc fingers: survey and summary. Nucleic Acids Res (2003) 3.94

Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication. Mol Cell (2006) 3.77

Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance. Microbiol Mol Biol Rev (2009) 3.62

Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase. Mol Cell Biol (2000) 3.52

Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein. Mol Cell Biol (1993) 3.39

A dependent pathway of gene functions leading to chromosome segregation in Saccharomyces cerevisiae. J Cell Biol (1982) 3.34

Interaction of Dbf4, the Cdc7 protein kinase regulatory subunit, with yeast replication origins in vivo. Science (1994) 3.16

The Cdc7 protein kinase is required for origin firing during S phase. Genes Dev (1998) 3.15

Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo. Nature (2003) 3.08

Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis. Genes Dev (1997) 3.05

Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway. EMBO J (1999) 3.03

Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. Mol Cell (2006) 3.00

Cdc7 is required throughout the yeast S phase to activate replication origins. Genes Dev (1998) 2.75

The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication. Mol Cell Biol (1994) 2.75

Interactions between BRCT repeats and phosphoproteins: tangled up in two. Trends Biochem Sci (2004) 2.63

Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin. J Biol Chem (2006) 2.14

Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication. EMBO J (1999) 2.01

Keep your fingers off my DNA: protein-protein interactions mediated by C2H2 zinc finger domains. Cell Biochem Biophys (2008) 1.95

REV1 protein interacts with PCNA: significance of the REV1 BRCT domain in vitro and in vivo. Mol Cell (2006) 1.85

A novel role for Cdc5p in DNA replication. Mol Cell Biol (1996) 1.84

Cdc7p-Dbf4p becomes famous in the cell cycle. J Cell Sci (2000) 1.83

Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7. EMBO J (1997) 1.78

Temperature-sensitive cdc7 mutations of Saccharomyces cerevisiae are suppressed by the DBF4 gene, which is required for the G1/S cell cycle transition. Genetics (1992) 1.76

Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation. Genes Dev (2009) 1.76

A further two mutants defective in initiation of the S phase in the yeast Saccharomyces cerevisiae. Mol Gen Genet (1982) 1.74

Cellular functions of DNA polymerase zeta and Rev1 protein. Adv Protein Chem (2004) 1.67

Gaps and forks in DNA replication: Rediscovering old models. DNA Repair (Amst) (2006) 1.67

Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast. J Biol Chem (1998) 1.65

CDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replication. Proc Natl Acad Sci U S A (1997) 1.56

An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing. Proc Natl Acad Sci U S A (2002) 1.55

Dbf4p, an essential S phase-promoting factor, is targeted for degradation by the anaphase-promoting complex. Mol Cell Biol (2000) 1.52

Ordered assembly of Sld3, GINS and Cdc45 is distinctly regulated by DDK and CDK for activation of replication origins. EMBO J (2006) 1.44

Cell cycle control of Cdc7p kinase activity through regulation of Dbf4p stability. Mol Cell Biol (1999) 1.41

A fission yeast gene, him1(+)/dfp1(+), encoding a regulatory subunit for Hsk1 kinase, plays essential roles in S-phase initiation as well as in S-phase checkpoint control and recovery from DNA damage. Mol Cell Biol (1999) 1.39

Schizosaccharomyces pombe Swi1, Swi3, and Hsk1 are components of a novel S-phase response pathway to alkylation damage. Mol Cell Biol (2005) 1.37

A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells. Mol Cell Biol (1999) 1.34

Hsk1-Dfp1/Him1, the Cdc7-Dbf4 kinase in Schizosaccharomyces pombe, associates with Swi1, a component of the replication fork protection complex. J Biol Chem (2005) 1.30

Cell cycle regulation of DNA replication initiator factor Dbf4p. Mol Cell Biol (1999) 1.29

cdc7-1 a temperature sensitive cell-cycle mutant which interferes with induced mutagenesis in Saccharomyces cerevisiae. Mol Gen Genet (1982) 1.28

CDC7/DBF4 functions in the translesion synthesis branch of the RAD6 epistasis group in Saccharomyces cerevisiae. Genetics (2004) 1.25

Characterization of the yeast Cdc7p/Dbf4p complex purified from insect cells. Its protein kinase activity is regulated by Rad53p. J Biol Chem (2000) 1.23

Premature structural changes at replication origins in a yeast minichromosome maintenance (MCM) mutant. J Biol Chem (2000) 1.21

Bipartite binding of a kinase activator activates Cdc7-related kinase essential for S phase. J Biol Chem (2001) 1.20

The Drosophila chiffon gene is required for chorion gene amplification, and is related to the yeast Dbf4 regulator of DNA replication and cell cycle. Development (1999) 1.13

A Dbf4p BRCA1 C-terminal-like domain required for the response to replication fork arrest in budding yeast. Genetics (2006) 1.12

A conserved domain of Schizosaccharomyces pombe dfp1(+) is uniquely required for chromosome stability following alkylation damage during S phase. Mol Cell Biol (2002) 1.08

Dbf4 motifs: conserved motifs in activation subunits for Cdc7 kinases essential for S-phase. Biochem Biophys Res Commun (2000) 1.02

Cyclin-specific control of ribosomal DNA segregation. Mol Cell Biol (2008) 0.95

Cell cycle regulation of chromatin binding and nuclear localization of human Cdc7-ASK kinase complex. Genes Cells (2003) 0.94

Cdc7p-Dbf4p regulates mitotic exit by inhibiting Polo kinase. PLoS Genet (2009) 0.93

Identification and characterization of a Xenopus homolog of Dbf4, a regulatory subunit of the Cdc7 protein kinase required for the initiation of DNA replication. J Biochem (2003) 0.93

nimO, an Aspergillus gene related to budding yeast Dbf4, is required for DNA synthesis and mitotic checkpoint control. J Cell Sci (1999) 0.93

Mutagenesis in cdc7 strains of yeast. The fate of premutational lesions induced by ultraviolet light. Mutat Res (1982) 0.80

Identification, characterization and chromosomal localization of the cognate human and murine DBF4 genes. Mol Gen Genet (1999) 0.78

Articles by these authors

Lung cysts, spontaneous pneumothorax, and genetic associations in 89 families with Birt-Hogg-Dubé syndrome. Am J Respir Crit Care Med (2007) 2.19

The NAD(+)-dependent Sir2p histone deacetylase is a negative regulator of chromosomal DNA replication. Genes Dev (2004) 1.43

The origin recognition complex and Sir4 protein recruit Sir1p to yeast silent chromatin through independent interactions requiring a common Sir1p domain. Mol Cell Biol (2004) 1.30

Parafibromin inhibits cancer cell growth and causes G1 phase arrest. Biochem Biophys Res Commun (2006) 1.25

Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex. Genes Dev (2014) 1.25

Cdc7-Dbf4 kinase overexpression in multiple cancers and tumor cell lines is correlated with p53 inactivation. Neoplasia (2008) 1.18

An ARS element inhibits DNA replication through a SIR2-dependent mechanism. Mol Cell (2008) 1.17

A Dbf4p BRCA1 C-terminal-like domain required for the response to replication fork arrest in budding yeast. Genetics (2006) 1.12

The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin. Genes Dev (2010) 1.11

Analysis of chromosome III replicators reveals an unusual structure for the ARS318 silencer origin and a conserved WTW sequence within the origin recognition complex binding site. Mol Cell Biol (2008) 1.00

The origin recognition complex interacts with a subset of metabolic genes tightly linked to origins of replication. PLoS Genet (2009) 0.98

Cdc7p-Dbf4p regulates mitotic exit by inhibiting Polo kinase. PLoS Genet (2009) 0.93

High-resolution analysis of four efficient yeast replication origins reveals new insights into the ORC and putative MCM binding elements. Nucleic Acids Res (2011) 0.93

Dbf4 regulates the Cdc5 Polo-like kinase through a distinct non-canonical binding interaction. J Biol Chem (2010) 0.91

Differential regulation of peripheral CD4+ T cell tolerance induced by deletion and TCR revision. J Immunol (2003) 0.85

DNA replication checkpoint signaling depends on a Rad53-Dbf4 N-terminal interaction in Saccharomyces cerevisiae. Genetics (2013) 0.84

Beyond heterochromatin: SIR2 inhibits the initiation of DNA replication. Cell Cycle (2008) 0.83

Modulating erythrocyte chimerism in a mouse model of pyruvate kinase deficiency. Blood (2004) 0.83

CDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor I with chromatin. Cell Cycle (2015) 0.79

Cardiorespiratory Fitness in Internal Medicine Residents: Are Future Physicians Becoming Deconditioned? J Grad Med Educ (2017) 0.75