Outer membrane vesicle-mediated release of cytolethal distending toxin (CDT) from Campylobacter jejuni.

PubWeight™: 1.19‹?› | Rank: Top 10%

🔗 View Article (PMC 2770062)

Published in BMC Microbiol on October 16, 2009

Authors

Barbro Lindmark1, Pramod Kumar Rompikuntal, Karolis Vaitkevicius, Tianyan Song, Yoshimitsu Mizunoe, Bernt Eric Uhlin, Patricia Guerry, Sun Nyunt Wai

Author Affiliations

1: Department of Molecular Biology, Umeå University, S-90187 Umeå, Sweden. barbro.lindmark@molbiol.umu.se

Articles citing this

Membrane vesicle release in bacteria, eukaryotes, and archaea: a conserved yet underappreciated aspect of microbial life. Infect Immun (2012) 1.73

Cytolethal distending toxin: a conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineages. Microbiology (2011) 1.40

Membrane Distribution of the Pseudomonas Quinolone Signal Modulates Outer Membrane Vesicle Production in Pseudomonas aeruginosa. MBio (2017) 1.37

Acinetobacter baumannii secretes cytotoxic outer membrane protein A via outer membrane vesicles. PLoS One (2011) 1.24

The biology of the cytolethal distending toxins. Toxins (Basel) (2011) 1.11

Enterotoxigenic Escherichia coli elicits immune responses to multiple surface proteins. Infect Immun (2010) 1.10

Perinuclear localization of internalized outer membrane vesicles carrying active cytolethal distending toxin from Aggregatibacter actinomycetemcomitans. Infect Immun (2011) 1.06

Bacterial outer membrane vesicles in disease and preventive medicine. Semin Immunopathol (2010) 1.05

Genome and proteome of Campylobacter jejuni bacteriophage NCTC 12673. Appl Environ Microbiol (2011) 1.01

Role of the Vibrio cholerae matrix protein Bap1 in cross-resistance to antimicrobial peptides. PLoS Pathog (2013) 0.99

Protein selection and export via outer membrane vesicles. Biochim Biophys Acta (2013) 0.99

Staphylococcus aureus α-toxin-dependent induction of host cell death by membrane-derived vesicles. PLoS One (2013) 0.98

Discovery of Salmonella virulence factors translocated via outer membrane vesicles to murine macrophages. Infect Immun (2011) 0.98

Campylobacter jejuni outer membrane vesicles play an important role in bacterial interactions with human intestinal epithelial cells. Infect Immun (2012) 0.98

Context-dependent activation kinetics elicited by soluble versus outer membrane vesicle-associated heat-labile enterotoxin. Infect Immun (2011) 0.91

Membrane vesicle-mediated release of bacterial RNA. Sci Rep (2015) 0.88

Outer membrane vesicles mediate transport of biologically active Vibrio cholerae cytolysin (VCC) from V. cholerae strains. PLoS One (2014) 0.87

Comprehensive proteomic profiling of outer membrane vesicles from Campylobacter jejuni. J Proteomics (2013) 0.85

The macrophage pattern recognition scavenger receptors SR-A and CD36 protect against microbial induced pregnancy loss. Inflamm Res (2010) 0.85

The cytolethal distending toxin effects on Mammalian cells: a DNA damage perspective. Cells (2014) 0.85

Cytotoxic effects of Kingella kingae outer membrane vesicles on human cells. Microb Pathog (2011) 0.83

Outer Membrane Vesicle-Mediated Export of Processed PrtV Protease from Vibrio cholerae. PLoS One (2015) 0.82

Calcium binding by the PKD1 domain regulates interdomain flexibility in Vibrio cholerae metalloprotease PrtV. FEBS Open Bio (2013) 0.82

Identification and characterization of outer membrane vesicle-associated proteins in Salmonella enterica serovar Typhimurium. Infect Immun (2014) 0.82

Outer membrane vesicles as platform vaccine technology. Biotechnol J (2015) 0.80

Uptake and processing of the cytolethal distending toxin by mammalian cells. Toxins (Basel) (2014) 0.80

Cytotoxic and Inflammatory Responses Induced by Outer Membrane Vesicle-Associated Biologically Active Proteases from Vibrio cholerae. Infect Immun (2016) 0.76

Mechanisms of outer membrane vesicle entry into host cells. Cell Microbiol (2016) 0.76

A Novel Role of Listeria monocytogenes Membrane Vesicles in Inhibition of Autophagy and Cell Death. Front Cell Infect Microbiol (2017) 0.75

Evaluation of a protective effect of in ovo delivered Campylobacter jejuni OMVs. Appl Microbiol Biotechnol (2016) 0.75

Molecular Mechanisms and Potential Clinical Applications of Campylobacter jejuni Cytolethal Distending Toxin. Front Cell Infect Microbiol (2016) 0.75

A Journey of Cytolethal Distending Toxins through Cell Membranes. Front Cell Infect Microbiol (2016) 0.75

Interaction of Bacteroides fragilis Toxin with Outer Membrane Vesicles Reveals New Mechanism of Its Secretion and Delivery. Front Cell Infect Microbiol (2017) 0.75

Cytolethal Distending Toxin From Campylobacter jejuni Requires the Cytoskeleton for Toxic Activity. Jundishapur J Microbiol (2016) 0.75

Spheres of hope, packets of doom: The good and bad of outer membrane vesicles in interspecies and ecological dynamics. J Bacteriol (2017) 0.75

Outer Membrane Vesicles (OMVs) of Gram-negative Bacteria: A Perspective Update. Front Microbiol (2017) 0.75

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

Morphological heterogeneity among Salmonella lipopolysaccharide chemotypes in silver-stained polyacrylamide gels. J Bacteriol (1983) 25.26

Guillain-Barré syndrome. Lancet (2005) 8.73

Experimental Campylobacter jejuni infection in humans. J Infect Dis (1988) 7.05

A bacterial toxin that controls cell cycle progression as a deoxyribonuclease I-like protein. Science (2000) 5.31

Membrane vesicles traffic signals and facilitate group activities in a prokaryote. Nature (2005) 4.17

Bacterial outer membrane vesicles and the host-pathogen interaction. Genes Dev (2005) 4.14

Vesicle-mediated export and assembly of pore-forming oligomers of the enterobacterial ClyA cytotoxin. Cell (2003) 3.88

A point-source outbreak of campylobacteriosis associated with consumption of raw milk. J Infect Dis (1985) 3.81

Improved silver staining procedure for fast staining in PhastSystem Development Unit. I. Staining of sodium dodecyl sulfate gels. Electrophoresis (1988) 3.75

A new heat-labile cytolethal distending toxin (CLDT) produced by Escherichia coli isolates from clinical material. Microb Pathog (1988) 3.31

A new heat-labile cytolethal distending toxin (CLDT) produced by Campylobacter spp. Microb Pathog (1988) 3.24

The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase. J Bacteriol (1990) 3.14

Prevalence of cytolethal distending toxin production in Campylobacter jejuni and relatedness of Campylobacter sp. cdtB gene. Infect Immun (1996) 2.85

Enterotoxigenic Escherichia coli secretes active heat-labile enterotoxin via outer membrane vesicles. J Biol Chem (2000) 2.63

Secretion of virulence proteins from Campylobacter jejuni is dependent on a functional flagellar export apparatus. J Bacteriol (2004) 2.20

CdtA, CdtB, and CdtC form a tripartite complex that is required for cytolethal distending toxin activity. Infect Immun (2001) 2.13

Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial-internalization pathway. Proc Natl Acad Sci U S A (2004) 1.99

Campylobacter jejuni cytolethal distending toxin mediates release of interleukin-8 from intestinal epithelial cells. Infect Immun (2000) 1.86

DNA sequence and mutational analyses of the pVir plasmid of Campylobacter jejuni 81-176. Infect Immun (2002) 1.68

Membrane vesicles are immunogenic facsimiles of Salmonella typhimurium that potently activate dendritic cells, prime B and T cell responses, and stimulate protective immunity in vivo. J Immunol (2007) 1.57

Escherichia coli CdtB mediates cytolethal distending toxin cell cycle arrest. Infect Immun (2001) 1.56

Cytolethal distending toxin: limited damage as a strategy to modulate cellular functions. Trends Microbiol (2002) 1.55

Active cytotoxic necrotizing factor 1 associated with outer membrane vesicles from uropathogenic Escherichia coli. Infect Immun (2006) 1.45

Release of the type I secreted alpha-haemolysin via outer membrane vesicles from Escherichia coli. Mol Microbiol (2006) 1.41

The galE gene of Campylobacter jejuni is involved in lipopolysaccharide synthesis and virulence. Infect Immun (2000) 1.41

Nucleoid proteins stimulate stringently controlled bacterial promoters: a link between the cAMP-CRP and the (p)ppGpp regulons in Escherichia coli. Cell (2000) 1.37

GroEL heat shock protein of Haemophilus ducreyi: association with cell surface and capacity to bind to eukaryotic cells. Infect Immun (1998) 1.32

Proteomics characterization of outer membrane vesicles from the extraintestinal pathogenic Escherichia coli DeltatolR IHE3034 mutant. Mol Cell Proteomics (2007) 1.30

GroEL of Lactobacillus johnsonii La1 (NCC 533) is cell surface associated: potential role in interactions with the host and the gastric pathogen Helicobacter pylori. Infect Immun (2006) 1.26

Immunolocalization of Hsp60 in Legionella pneumophila. J Bacteriol (1998) 1.25

Cytolethal distending toxins. Rev Physiol Biochem Pharmacol (2004) 1.24

CD4+ T cells and toll-like receptors recognize Salmonella antigens expressed in bacterial surface organelles. Infect Immun (2005) 1.20

Membrane vesicles shed by Legionella pneumophila inhibit fusion of phagosomes with lysosomes. Infect Immun (2006) 1.20

Cholesterol-rich membrane microdomains mediate cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal-distending toxin. Cell Microbiol (2006) 1.11

Recent developments in Campylobacter pathogenesis. Curr Opin Infect Dis (2003) 1.07

Purification, characterization and sequence analysis of Omp50,a new porin isolated from Campylobacter jejuni. Biochem J (2000) 1.05

Pathogenesis of enteric Campylobacter infection. Symp Ser Soc Appl Microbiol (2001) 1.03

Cytolethal distending toxin: creating a gap in the cell cycle. J Med Microbiol (2005) 0.97

Differences in virulence attributes between cytolethal distending toxin positive and negative Campylobacter jejuni strains. J Med Microbiol (2008) 0.96

Biogenesis of the Actinobacillus actinomycetemcomitans cytolethal distending toxin holotoxin. Infect Immun (2006) 0.90

Free-soluble and outer membrane vesicle-associated VacA from Helicobacter pylori: Two forms of release, a different activity. Biochem Biophys Res Commun (2005) 0.90

Clinical relevance of virulence genes in Campylobacter jejuni isolates in Bahrain. J Med Microbiol (2006) 0.88

Causative pathogens of severe diarrhea in children. Saudi Med J (2002) 0.85

Detection of seven virulence and toxin genes of Campylobacter jejuni isolates from Danish turkeys by PCR and cytolethal distending toxin production of the isolates. J Food Prot (2004) 0.81

Articles by these authors

The Listeria transcriptional landscape from saprophytism to virulence. Nature (2009) 5.88

Vesicle-mediated export and assembly of pore-forming oligomers of the enterobacterial ClyA cytotoxin. Cell (2003) 3.88

Staphylococcus epidermidis Esp inhibits Staphylococcus aureus biofilm formation and nasal colonization. Nature (2010) 2.85

A trans-acting riboswitch controls expression of the virulence regulator PrfA in Listeria monocytogenes. Cell (2009) 2.62

Campylobacter protein glycosylation affects host cell interactions. Infect Immun (2002) 2.17

Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors. Nature (2013) 2.11

A new Vibrio cholerae sRNA modulates colonization and affects release of outer membrane vesicles. Mol Microbiol (2008) 1.83

A Vibrio cholerae protease needed for killing of Caenorhabditis elegans has a role in protection from natural predator grazing. Proc Natl Acad Sci U S A (2006) 1.78

Nucleotide sequences and comparison of two large conjugative plasmids from different Campylobacter species. Microbiology (2004) 1.73

Distribution of putative adhesins in different seropathotypes of Shiga toxin-producing Escherichia coli. J Clin Microbiol (2004) 1.70

DNA sequence and mutational analyses of the pVir plasmid of Campylobacter jejuni 81-176. Infect Immun (2002) 1.68

Pseudaminic acid, the major modification on Campylobacter flagellin, is synthesized via the Cj1293 gene. Mol Microbiol (2003) 1.62

Genome sequence of a clinical isolate of Campylobacter jejuni from Thailand. Infect Immun (2007) 1.61

Curli fibers are required for development of biofilm architecture in Escherichia coli K-12 and enhance bacterial adherence to human uroepithelial cells. Microbiol Immunol (2005) 1.61

Structural heterogeneity of carbohydrate modifications affects serospecificity of Campylobacter flagellins. Mol Microbiol (2002) 1.58

Differential effects and interactions of endogenous and horizontally acquired H-NS-like proteins in pathogenic Escherichia coli. Mol Microbiol (2009) 1.56

N-linked protein glycosylation is required for full competence in Campylobacter jejuni 81-176. J Bacteriol (2004) 1.54

Divergence of quaternary structures among bacterial flagellar filaments. Science (2008) 1.46

Heterogeneity of a Campylobacter jejuni protein that is secreted through the flagellar filament. Infect Immun (2007) 1.46

Physical properties of Escherichia coli P pili measured by optical tweezers. Biophys J (2004) 1.45

Active cytotoxic necrotizing factor 1 associated with outer membrane vesicles from uropathogenic Escherichia coli. Infect Immun (2006) 1.45

Type VI secretion modulates quorum sensing and stress response in Vibrio anguillarum. Environ Microbiol (2009) 1.41

The iron-binding protein Dps confers hydrogen peroxide stress resistance to Campylobacter jejuni. J Bacteriol (2003) 1.41

Release of the type I secreted alpha-haemolysin via outer membrane vesicles from Escherichia coli. Mol Microbiol (2006) 1.41

Functional characterization of flagellin glycosylation in Campylobacter jejuni 81-176. J Bacteriol (2009) 1.38

Quorum sensing regulation of the two hcp alleles in Vibrio cholerae O1 strains. PLoS One (2009) 1.37

Characterization of a pore-forming cytotoxin expressed by Salmonella enterica serovars typhi and paratyphi A. Infect Immun (2002) 1.36

Role of histone-like proteins H-NS and StpA in expression of virulence determinants of uropathogenic Escherichia coli. J Bacteriol (2006) 1.34

Functional characterization of the flagellar glycosylation locus in Campylobacter jejuni 81-176 using a focused metabolomics approach. J Biol Chem (2006) 1.27

Proximal small intestinal microbiota and identification of rod-shaped bacteria associated with childhood celiac disease. Am J Gastroenterol (2009) 1.26

Proteomic characterization of the whole secretome of Legionella pneumophila and functional analysis of outer membrane vesicles. Infect Immun (2008) 1.24

Pathoadaptive conditional regulation of the type VI secretion system in Vibrio cholerae O1 strains. Infect Immun (2011) 1.20

Type 1 fimbriae, a colonization factor of uropathogenic Escherichia coli, are controlled by the metabolic sensor CRP-cAMP. PLoS Pathog (2009) 1.20

Optical tweezers based force measurement system for quantitating binding interactions: system design and application for the study of bacterial adhesion. Biosens Bioelectron (2004) 1.19

Intracellular survival of Campylobacter jejuni in human monocytic cells and induction of apoptotic death by cytholethal distending toxin. Infect Immun (2005) 1.18

YdgT, the Hha paralogue in Escherichia coli, forms heteromeric complexes with H-NS and StpA. Mol Microbiol (2004) 1.18

Biochemical and functional characterization of Helicobacter pylori vesicles. Mol Microbiol (2010) 1.18

Mosaic structure of a multiple-drug-resistant, conjugative plasmid from Campylobacter jejuni. Antimicrob Agents Chemother (2005) 1.18

A sigma28-regulated nonflagella gene contributes to virulence of Campylobacter jejuni 81-176. Infect Immun (2006) 1.17

A deep-rough mutant of Campylobacter jejuni 81-176 is noninvasive for intestinal epithelial cells. Infect Immun (2004) 1.17

Staphylococcus epidermidis Esp degrades specific proteins associated with Staphylococcus aureus biofilm formation and host-pathogen interaction. J Bacteriol (2013) 1.15

Role of melanin pigment in expression of Vibrio cholerae virulence factors. Infect Immun (2008) 1.11

Characterization of dominantly negative mutant ClyA cytotoxin proteins in Escherichia coli. J Bacteriol (2003) 1.10

A sticky chain model of the elongation and unfolding of Escherichia coli P pili under stress. Biophys J (2005) 1.10

Pathogenesis of Campylobacter. Curr Opin Gastroenterol (2008) 1.10

Capsule polysaccharide conjugate vaccine against diarrheal disease caused by Campylobacter jejuni. Infect Immun (2008) 1.09

Targeted metabolomics analysis of Campylobacter coli VC167 reveals legionaminic acid derivatives as novel flagellar glycans. J Biol Chem (2007) 1.08

The biomechanical properties of E. coli pili for urinary tract attachment reflect the host environment. Biophys J (2007) 1.07

Immunogenicity and protective efficacy of recombinant Campylobacter jejuni flagellum-secreted proteins in mice. Infect Immun (2008) 1.07

Perinuclear localization of internalized outer membrane vesicles carrying active cytolethal distending toxin from Aggregatibacter actinomycetemcomitans. Infect Immun (2011) 1.06

The polysaccharide capsule of Campylobacter jejuni modulates the host immune response. Infect Immun (2012) 1.05

Mutation of waaC, encoding heptosyltransferase I in Campylobacter jejuni 81-176, affects the structure of both lipooligosaccharide and capsular carbohydrate. J Bacteriol (2006) 1.01

Characterization of two Campylobacter jejuni strains for use in volunteer experimental-infection studies. Infect Immun (2008) 1.00

Role of fibronectin-binding proteins A and B in in vitro cellular infections and in vivo septic infections by Staphylococcus aureus. Infect Immun (2011) 1.00

Vesicular stabilization and activity augmentation of enterohaemorrhagic Escherichia coli haemolysin. Mol Microbiol (2009) 1.00

Dynamic force spectroscopy of E. coli P pili. Biophys J (2006) 1.00

Physical properties of biopolymers assessed by optical tweezers: analysis of folding and refolding of bacterial pili. Chemphyschem (2008) 0.99

Transcriptional analysis of the sfa determinant revealing mmRNA processing events in the biogenesis of S fimbriae in pathogenic Escherichia coli. J Bacteriol (2003) 0.99

Role of the Vibrio cholerae matrix protein Bap1 in cross-resistance to antimicrobial peptides. PLoS Pathog (2013) 0.99

Selective detection and identification of sugar nucleotides by CE-electrospray-MS and its application to bacterial metabolomics. Anal Chem (2004) 0.99

Staphylococcus aureus α-toxin-dependent induction of host cell death by membrane-derived vesicles. PLoS One (2013) 0.98

Regulatory Interactions among adhesin gene systems of uropathogenic Escherichia coli. Infect Immun (2007) 0.96

A simple assay for measuring catalase activity: a visual approach. Sci Rep (2013) 0.95

Recrudescent Campylobacter jejuni infection in an immunocompetent adult following experimental infection with a well-characterized organism. Clin Vaccine Immunol (2009) 0.94

Unfolding and refolding properties of S pili on extraintestinal pathogenic Escherichia coli. Eur Biophys J (2009) 0.94

Immune response to and histopathology of Campylobacter jejuni infection in ferrets (Mustela putorius furo). Comp Med (2009) 0.94

Pilicides regulate pili expression in E. coli without affecting the functional properties of the pilus rod. Mol Biosyst (2007) 0.93

Effects of the Escherichia coli toxin cytolysin A on mucosal immunostimulation via epithelial Ca2+ signalling and Toll-like receptor 4. Cell Microbiol (2005) 0.93

Vibrio cholerae SXT element, Laos. Emerg Infect Dis (2005) 0.93

Fast uncoiling kinetics of F1C pili expressed by uropathogenic Escherichia coli are revealed on a single pilus level using force-measuring optical tweezers. Eur Biophys J (2010) 0.92

Glucose triggers ATP secretion from bacteria in a growth-phase-dependent manner. Appl Environ Microbiol (2013) 0.91

The bacteriophage-associated ehly1 and ehly2 determinants from Escherichia coli O26:H- strains do not encode enterohemolysins per se but cause release of the ClyA cytolysin. Int J Med Microbiol (2002) 0.91

Enhanced biofilm formation by Escherichia coli LPS mutants defective in Hep biosynthesis. PLoS One (2012) 0.91

Effects of bacteriocins on methicillin-resistant Staphylococcus aureus biofilm. Antimicrob Agents Chemother (2013) 0.90

Studies on a novel serine protease of a ΔhapAΔprtV Vibrio cholerae O1 strain and its role in hemorrhagic response in the rabbit ileal loop model. PLoS One (2010) 0.90

Campylobacter jejuni strain CG8421: a refined model for the study of Campylobacteriosis and evaluation of Campylobacter vaccines in human subjects. Clin Infect Dis (2009) 0.90

VrrA mediates Hfq-dependent regulation of OmpT synthesis in Vibrio cholerae. J Mol Biol (2010) 0.90

Legionella dumoffii DjlA, a member of the DnaJ family, is required for intracellular growth. Infect Immun (2004) 0.90

Discrimination of major capsular types of Campylobacter jejuni by multiplex PCR. J Clin Microbiol (2011) 0.90

Structure of a sigma28-regulated nonflagellar virulence protein from Campylobacter jejuni. J Mol Biol (2008) 0.90

The metalloprotease PrtV from Vibrio cholerae. FEBS J (2008) 0.89

Confocal imaging of biofilm formation process using fluoroprobed Escherichia coli and fluoro-stained exopolysaccharide. J Biomed Mater Res A (2004) 0.89

A structural basis for sustained bacterial adhesion: biomechanical properties of CFA/I pili. J Mol Biol (2011) 0.89