Published in Eur Respir J on October 19, 2009
NET balancing: a problem in inflammatory lung diseases. Front Immunol (2013) 1.61
Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR. PLoS One (2011) 1.58
Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice. Inflamm Res (2011) 0.92
Impact of azithromycin treatment on macrophage gene expression in subjects with cystic fibrosis. J Cyst Fibros (2013) 0.78
Why is Pseudomonas aeruginosa a pathogen? F1000 Biol Rep (2010) 0.78
Reactive-oxygen-species-mediated P. aeruginosa killing is functional in human cystic fibrosis macrophages. PLoS One (2013) 0.78
An Exploration of Charge Compensating Ion Channels across the Phagocytic Vacuole of Neutrophils. Front Pharmacol (2017) 0.75
Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils. Hum Vaccin Immunother (2016) 0.75
Interactions between Neutrophils and Pseudomonas aeruginosa in Cystic Fibrosis. Pathogens (2017) 0.75
Human Cystic Fibrosis Macrophages Have Defective Calcium-Dependent Protein Kinase C Activation of the NADPH Oxidase, an Effect Augmented by Burkholderia cenocepacia. J Immunol (2017) 0.75
Inflammation and Oxidation Biomarkers in Patients with Cystic Fibrosis: The Influence of Azithromycin. Eurasian J Med (2017) 0.75
Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr (1981) 7.49
British Thoracic Society guideline for non-CF bronchiectasis. Thorax (2010) 2.95
Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo. Nat Med (1999) 2.92
An investigation into causative factors in patients with bronchiectasis. Am J Respir Crit Care Med (2000) 2.81
PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40(phox). Nat Cell Biol (2001) 2.39
Severe bone pain after intravenous pamidronate in adult patients with cystic fibrosis. Lancet (1998) 2.30
Clinical outcome in relation to care in centres specialising in cystic fibrosis: cross sectional study. BMJ (1998) 2.22
Treatment compliance in adults with cystic fibrosis. Thorax (1994) 1.93
Nontuberculous mycobacteria in bronchiectasis: Prevalence and patient characteristics. Eur Respir J (2006) 1.91
NF-kappaB activation is a critical regulator of human granulocyte apoptosis in vitro. J Biol Chem (1999) 1.89
Audit of oxygen prescribing before and after the introduction of a prescription chart. BMJ (2000) 1.82
Improved survival at low lung function in cystic fibrosis: cohort study from 1990 to 2007. BMJ (2011) 1.74
Neutrophil priming: pathophysiological consequences and underlying mechanisms. Clin Sci (Lond) (1998) 1.69
Regulation of neutrophil apoptosis by tumor necrosis factor-alpha: requirement for TNFR55 and TNFR75 for induction of apoptosis in vitro. Blood (1997) 1.63
A randomised controlled crossover trial of nurse practitioner versus doctor led outpatient care in a bronchiectasis clinic. Thorax (2002) 1.56
Recommendations for the classification of diseases as CFTR-related disorders. J Cyst Fibros (2011) 1.54
Kinetics of pulmonary neutrophil recruitment and clearance in a natural and spontaneously resolving model of airway inflammation. Clin Exp Allergy (2005) 1.54
Effects of the cyclin-dependent kinase inhibitor R-roscovitine on eosinophil survival and clearance. Clin Exp Allergy (2011) 1.53
Phosphatidylinositol 3-phosphate is generated in phagosomal membranes. Curr Biol (2001) 1.49
Phenotypic variability of Pseudomonas aeruginosa in sputa from patients with acute infective exacerbation of cystic fibrosis and its impact on the validity of antimicrobial susceptibility testing. J Antimicrob Chemother (2005) 1.48
Lung polymers in Z alpha1-antitrypsin deficiency-related emphysema. Am J Respir Cell Mol Biol (1998) 1.47
Efficacy and tolerability of anti-immunoglobulin E therapy with omalizumab in patients with poorly controlled (moderate-to-severe) allergic asthma. Allergy (2004) 1.46
D-dimer assay for deep vein thrombosis: its role with colour Doppler sonography. Clin Radiol (2000) 1.42
Regulation of macrophage phagocytosis of apoptotic cells by cAMP. J Immunol (1998) 1.41
Optic pathway glioma infiltrating into somatostatinergic pathways in a young boy with gigantism. Case report. J Neurosurg (1994) 1.40
Hypoxia prolongs neutrophil survival in vitro. FEBS Lett (1995) 1.40
Sputum and serum pharmacokinetics of loracarbef (LY163892) in patients with chronic bronchial sepsis. J Antimicrob Chemother (1994) 1.39
Time to extend 'the timetable of tuberculosis'? Respir Med (1994) 1.37
The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70s6k-dependent pathway. Cancer Res (1998) 1.37
Heterogeneity of [3H]inositol 1,4,5-trisphosphate binding sites in adrenal-cortical membranes. Characterization and validation of a radioreceptor assay. Biochem J (1990) 1.34
Microbiological profile of community-acquired pneumonia in adults over the last 20 years. J Infect (2005) 1.33
Antioxidant therapy for recurrent pancreatitis: placebo-controlled trial. Aliment Pharmacol Ther (1990) 1.32
Quantification of right to left shunt at rest and during exercise in patients with pulmonary arteriovenous malformations. Thorax (1992) 1.27
Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation. Am J Physiol (1999) 1.18
Formaldehyde as a pre-treatment for dermal collagen heterografts. Biochim Biophys Acta (1980) 1.17
Umbravirus gene expression helps potato leafroll virus to invade mesophyll tissues and to be transmitted mechanically between plants. Virology (2001) 1.11
Cost-effectiveness of brief psychodynamic-interpersonal therapy in high utilizers of psychiatric services. Arch Gen Psychiatry (1999) 1.11
A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis. Gene Ther (1997) 1.11
Aspergillus epidural abscess and cord compression in a patient with aspergilloma and empyema. Survival and response to high dose systemic amphotericin therapy. Am Rev Respir Dis (1992) 1.11
Priming differentially regulates neutrophil adhesion molecule expression/function. Immunology (1996) 1.10
Agents that elevate cAMP inhibit human neutrophil apoptosis. Biochem Biophys Res Commun (1995) 1.10
Regulation of mitogen-activated protein kinase phosphatase-1 expression by extracellular signal-related kinase-dependent and Ca2+-dependent signal pathways in Rat-1 cells. J Biol Chem (1997) 1.08
The United Kingdom Primary Immune Deficiency (UKPID) Registry: report of the first 4 years' activity 2008-2012. Clin Exp Immunol (2014) 1.08
Characteristics of adults with and without cystic fibrosis-related diabetes. Diabet Med (2007) 1.08
Recognising severe pneumonia with simple clinical and biochemical measurements. Clin Med (2003) 1.07
Alpha1-antitrypsin deficiency alleles and the Taq-I G-->A allele in cystic fibrosis lung disease. Eur Respir J (1998) 1.07
Is the neutrophil the key effector cell in severe asthma? Thorax (2005) 1.06
Evidence for early oxidative stress in acute pancreatitis. Clues for correction. Int J Pancreatol (1995) 1.05
A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor-stimulated bovine airway smooth-muscle cells. Biochem J (1996) 1.05
Prolonged survival of neutrophils from patients with Delta F508 CFTR mutations. Thorax (2008) 1.05
Structural explanation for the deficiency of S alpha 1-antitrypsin. Nat Struct Biol (1996) 1.04
Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages. Cell Signal (1999) 1.03
Pharmacological manipulation of granulocyte apoptosis: potential therapeutic targets. Trends Pharmacol Sci (1999) 1.03
What can we learn from highly purified neutrophils? Biochem Soc Trans (2004) 1.03
Continuous intrathecal baclofen in spinal cord spasticity. A prospective study. Am J Phys Med Rehabil (1992) 1.02
Phenotypic diversity and molecular mechanisms of airway smooth muscle proliferation in asthma. Eur Respir J (2000) 1.01
Rate of digestion of foods and postprandial glycaemia in normal and diabetic subjects. Br Med J (1980) 1.01
British Thoracic Society guideline for non-CF bronchiectasis. Thorax (2010) 1.01
Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: role in mediating airway smooth muscle proliferation. Mol Pharmacol (1998) 1.00
Effect of exercise and physiotherapy in aiding sputum expectoration in adults with cystic fibrosis. Thorax (1989) 0.99
Exacerbations in cystic fibrosis: 4--Non-cystic fibrosis bronchiectasis. Thorax (2008) 0.99
Induction of human neutrophil apoptosis by nitric oxide donors: evidence for a caspase-dependent, cyclic-GMP-independent, mechanism. Biochem Pharmacol (2000) 0.98
Demonstration of reversible priming of human neutrophils using platelet-activating factor. Blood (1996) 0.97
A comparison of the effects of SCA40, NS 004 and NS 1619 on large conductance Ca(2+)-activated K+ channels in bovine tracheal smooth muscle cells in culture. Br J Pharmacol (1995) 0.96
Profound overexpression of leukotriene C4 synthase in bronchial biopsies from aspirin-intolerant asthmatic patients. Int Arch Allergy Immunol (1997) 0.94
Inhibition of neuropeptide-stimulated tyrosine phosphorylation and tyrosine kinase activity stimulates apoptosis in small cell lung cancer cells. Cancer Res (1996) 0.93
A single centre experience of liver disease in adults with cystic fibrosis 1995-2006. J Cyst Fibros (2007) 0.93
The actions of cyclic AMP, its butyryl derivatives and Na butyrate on the proliferation of malignant trophoblast cells in vitro. Br J Cancer (1977) 0.92
Fungal beta-tubulin, expressed as a fusion protein, binds benzimidazole and phenylcarbamate fungicides. Antimicrob Agents Chemother (1998) 0.91
Role of neutrophil apoptosis in the resolution of pulmonary inflammation. Monaldi Arch Chest Dis (1999) 0.91
Miliary tuberculosis in Edinburgh--a comparison between 1984-1992 and 1954-1967. Respir Med (1994) 0.90
Recovery of spermatogenesis following bone marrow transplantation. Bone Marrow Transplant (1998) 0.90
Effects of S-salbutamol on human isolated bronchus. Pulm Pharmacol Ther (1998) 0.89
Dissociation of lipopolysaccharide-mediated induction of nitric oxide synthase and inhibition of DNA synthesis in RAW 264.7 macrophages and rat aortic smooth muscle cells. Br J Pharmacol (1997) 0.89
RNA and protein components of maize streak and cassava latent viruses. Ann Appl Biol (1977) 0.89
Stimulation by endothelin-1 of mitogen-activated protein kinases and DNA synthesis in bovine tracheal smooth muscle cells. Br J Pharmacol (1995) 0.87
Breeding virus resistant potatoes (Solanum tuberosum): a review of traditional and molecular approaches. Heredity (Edinb) (2001) 0.87
The function and fate of neutrophils at the inflamed site: prospects for therapeutic intervention. J R Coll Physicians Lond (2000) 0.87
Anti-neutrophil cytoplasmic antibodies (ANCA) against bactericidal/permeability-increasing protein (BPI) and cystic fibrosis lung disease. Clin Exp Immunol (1999) 0.86
Alpha-1 antitrypsin deficiency alleles and severe cystic fibrosis lung disease. Thorax (1998) 0.86
Influenza vaccination in adults with cystic fibrosis. BMJ (1991) 0.86
Beta-adrenoceptor induced inhibition of muscarinic receptor-stimulated phosphoinositide metabolism is agonist specific in bovine tracheal smooth muscle. Eur J Pharmacol (1991) 0.86
3H-collagen turnover in non-cross-linked and aldehyde-cross-linked dermal collagen grafts. Br J Exp Pathol (1982) 0.86
Profound adrenal suppression secondary to treatment with low dose inhaled steroids and itraconazole in allergic bronchopulmonary aspergillosis in cystic fibrosis. Thorax (2002) 0.85
Characterization of the survival effect of tumour necrosis factor-alpha in human neutrophils. Biochem Soc Trans (2004) 0.84
Upper airway 2: Bronchiectasis, cystic fibrosis and sinusitis. Thorax (2009) 0.84