Published in Bipolar Disord on December 01, 2009
Molecular actions and clinical pharmacogenetics of lithium therapy. Pharmacol Biochem Behav (2014) 0.94
Molecular pharmacology in a simple model system: implicating MAP kinase and phosphoinositide signalling in bipolar disorder. Semin Cell Dev Biol (2010) 0.87
International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases. Pharmacol Rev (2017) 0.83
Differential effects of antidepressants escitalopram versus lithium on Gs alpha membrane relocalization. BMC Neurosci (2015) 0.76
A fully integrated new paradigm for lithium's mode of action - lithium utilizes latent cellular fail-safe mechanisms. Neuropsychiatr Dis Treat (2017) 0.75
The Neuroprotective Effect of Lithium in cannabinoid Dependence is Mediated through Modulation of Cyclic AMP, ERK1/2 and GSK-3β Phosphorylation in Cerebellar Granular Neurons of Rat. Iran J Pharm Res (2015) 0.75
Effect of lithium chloride on the luteal steroidogenesis in gonadotropin-stimulated rat. Iran J Reprod Med (2012) 0.75
Major depressive disorder. N Engl J Med (2008) 6.61
Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res (2007) 5.23
Cardiac myosin activation: a potential therapeutic approach for systolic heart failure. Science (2011) 4.36
Autophagy in chronically ischemic myocardium. Proc Natl Acad Sci U S A (2005) 3.55
Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes. Circ Res (2009) 3.53
Type 5 adenylyl cyclase disruption increases longevity and protects against stress. Cell (2007) 2.96
Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. Circ Res (2004) 2.82
Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy. Circulation (2006) 2.50
A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy. Cell (2008) 2.47
Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy. J Clin Invest (2003) 2.20
Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy. J Clin Invest (2003) 2.19
Repetitive ischemia by coronary stenosis induces a novel window of ischemic preconditioning. Circulation (2008) 2.09
Rapid tryptophan depletion as a treatment for acute mania: a double-blind, pilot-controlled study. Bipolar Disord (2007) 1.99
Lipid-based nanoparticles as pharmaceutical drug carriers: from concepts to clinic. Crit Rev Ther Drug Carrier Syst (2009) 1.73
Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies. Biochem Biophys Res Commun (2004) 1.69
A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia. Schizophr Res (2006) 1.67
Disruption of type 5 adenylyl cyclase gene preserves cardiac function against pressure overload. Proc Natl Acad Sci U S A (2003) 1.64
Elevated homocysteine levels in young male patients with schizophrenia. Am J Psychiatry (2002) 1.62
Endocytosis machinery is required for beta1-adrenergic receptor-induced hypertrophy in neonatal rat cardiac myocytes. Cardiovasc Res (2008) 1.59
Improvement of cardiac function by a cardiac Myosin activator in conscious dogs with systolic heart failure. Circ Heart Fail (2010) 1.57
Short communication: vascular smooth muscle cell stiffness as a mechanism for increased aortic stiffness with aging. Circ Res (2010) 1.56
Cardiac-specific overexpression of caveolin-3 induces endogenous cardiac protection by mimicking ischemic preconditioning. Circulation (2008) 1.56
The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy. J Clin Invest (2002) 1.56
Omega-3 eicosapentaenoic acid in bipolar depression: report of a small open-label study. J Clin Psychiatry (2005) 1.54
Epac increases melanoma cell migration by a heparan sulfate-related mechanism. Am J Physiol Cell Physiol (2009) 1.54
Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia. Cardiovasc Res (2011) 1.49
DNA microarray profiling identified a new role of growth hormone in vascular remodeling of rat ductus arteriosus. J Physiol Sci (2011) 1.49
Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus. Circ Res (2005) 1.48
Mechanism of enhanced cardiac function in mice with hypertrophy induced by overexpressed Akt. J Biol Chem (2003) 1.47
Molecular mechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion. Autophagy (2008) 1.46
Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice. J Clin Invest (2005) 1.45
Cardiac nerves affect myocardial stunning through reactive oxygen and nitric oxide mechanisms. Circ Res (2003) 1.45
Caveolin gene transfer improves glucose metabolism in diabetic mice. Am J Physiol Cell Physiol (2009) 1.45
Effect of prolonged phenytoin administration on rat brain gene expression assessed by DNA microarrays. Exp Biol Med (Maywood) (2010) 1.44
Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling. J Biol Chem (2003) 1.44
Aging increases aortic MMP-2 activity and angiotensin II in nonhuman primates. Hypertension (2003) 1.41
Double-Blind, Randomized, Placebo-Controlled Trial of Metoclopramide for Hypersalivation Associated With Clozapine. J Clin Psychopharmacol (2016) 1.39
Curcumin as an add-on to antidepressive treatment: a randomized, double-blind, placebo-controlled, pilot clinical study. Clin Neuropharmacol (2013) 1.39
Mechanism of gender-specific differences in aortic stiffness with aging in nonhuman primates. Circulation (2007) 1.38
Disruption of type 5 adenylyl cyclase enhances desensitization of cyclic adenosine monophosphate signal and increases Akt signal with chronic catecholamine stress. Circulation (2007) 1.37
Valproate decreases inositol biosynthesis. Biol Psychiatry (2004) 1.33
Motor dysfunction in type 5 adenylyl cyclase-null mice. J Biol Chem (2003) 1.32
Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration. J Biol Chem (2004) 1.31
Chronic activation of the prostaglandin receptor EP4 promotes hyaluronan-mediated neointimal formation in the ductus arteriosus. J Clin Invest (2006) 1.29
Paradoxical cellular Ca2+ signaling in severe but compensated canine left ventricular hypertrophy. Circ Res (2005) 1.29
Caveolin-3 expression and caveolae are required for isoflurane-induced cardiac protection from hypoxia and ischemia/reperfusion injury. J Mol Cell Cardiol (2007) 1.28
Program of cell survival underlying human and experimental hibernating myocardium. Circ Res (2004) 1.27
Echocardiography in Mice. Curr Protoc Mouse Biol (2011) 1.27
Type 5 adenylyl cyclase disruption alters not only sympathetic but also parasympathetic and calcium-mediated cardiac regulation. Circ Res (2003) 1.25
Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells. Proc Natl Acad Sci U S A (2004) 1.25
Modulation of beta-adrenergic receptor signaling in heart failure and longevity: targeting adenylyl cyclase type 5. Heart Fail Rev (2010) 1.24
Proteasome inhibition decreases cardiac remodeling after initiation of pressure overload. Am J Physiol Heart Circ Physiol (2008) 1.23
Sex-specific regulation of gene expression in the aging monkey aorta. Physiol Genomics (2007) 1.23
Developmental changes in gene expression of Epac and its upregulation in myocardial hypertrophy. Am J Physiol Heart Circ Physiol (2007) 1.23
Aging increases stiffness of cardiac myocytes measured by atomic force microscopy nanoindentation. Am J Physiol Heart Circ Physiol (2004) 1.19
H11 kinase prevents myocardial infarction by preemptive preconditioning of the heart. Circ Res (2005) 1.19
Inhibition of p38 alpha MAPK rescues cardiomyopathy induced by overexpressed beta 2-adrenergic receptor, but not beta 1-adrenergic receptor. J Clin Invest (2007) 1.17
Adenylyl cyclase type 5 protein expression during cardiac development and stress. Am J Physiol Heart Circ Physiol (2009) 1.16
Is treating cardiac hypertrophy salutary or detrimental: the two faces of Janus. Am J Physiol Heart Circ Physiol (2003) 1.15
Increased vascular smooth muscle cell stiffness: a novel mechanism for aortic stiffness in hypertension. Am J Physiol Heart Circ Physiol (2013) 1.14
GSK-3 and the neurodevelopmental hypothesis of schizophrenia. Eur Neuropsychopharmacol (2002) 1.13
Glycogen synthase kinase-3beta heterozygote knockout mice as a model of findings in postmortem schizophrenia brain or as a model of behaviors mimicking lithium action: negative results. Behav Pharmacol (2008) 1.12
Adenylyl cyclase type 5 contributes to corticostriatal plasticity and striatum-dependent learning. J Neurosci (2009) 1.11
FGF induces hypertrophy and angiogenesis in hibernating myocardium. Circ Res (2005) 1.11
Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy. Circulation (2003) 1.10
H11 kinase is a novel mediator of myocardial hypertrophy in vivo. Circ Res (2002) 1.09
H11 kinase/heat shock protein 22 deletion impairs both nuclear and mitochondrial functions of STAT3 and accelerates the transition into heart failure on cardiac overload. Circulation (2011) 1.09
Caloric restriction reduces growth of mammary tumors and metastases. Carcinogenesis (2011) 1.09
Autophagy in ischemic preconditioning and hibernating myocardium. Autophagy (2009) 1.09
Persistent stunning induces myocardial hibernation and protection: flow/function and metabolic mechanisms. Circ Res (2003) 1.09
Relation of shyness in grade school children to the genotype for the long form of the serotonin transporter promoter region polymorphism. Am J Psychiatry (2003) 1.09
The prostanoid EP4 receptor and its signaling pathway. Pharmacol Rev (2013) 1.08
Congenital semilunar valvulogenesis defect in mice deficient in phospholipase C epsilon. Mol Cell Biol (2005) 1.08
Glycation end-product cross-link breaker reduces collagen and improves cardiac function in aging diabetic heart. Am J Physiol Heart Circ Physiol (2003) 1.08
Multiple transcripts of Ca2+ channel alpha1-subunits and a novel spliced variant of the alpha1C-subunit in rat ductus arteriosus. Am J Physiol Heart Circ Physiol (2005) 1.07
Insulin resistance in skeletal muscles of caveolin-3-null mice. Proc Natl Acad Sci U S A (2004) 1.07
Prolyl 3-hydroxylase 1 null mice display abnormalities in fibrillar collagen-rich tissues such as tendons, skin, and bones. J Biol Chem (2010) 1.06
Epac1 is upregulated during neointima formation and promotes vascular smooth muscle cell migration. Am J Physiol Heart Circ Physiol (2008) 1.06
Cardioprotection in stunned and hibernating myocardium. Heart Fail Rev (2007) 1.05
Impaired Ca2+ store functions in skeletal and cardiac muscle cells from sarcalumenin-deficient mice. J Biol Chem (2004) 1.05
Psychotropic drugs affect Ser9-phosphorylated GSK-3 beta protein levels in rodent frontal cortex. Int J Neuropsychopharmacol (2005) 1.05
Human 1-D-myo-inositol-3-phosphate synthase is functional in yeast. J Biol Chem (2004) 1.04
Insights into cardioprotection obtained from study of cellular Ca2+ handling in myocardium of true hibernating mammals. Am J Physiol Heart Circ Physiol (2004) 1.03
Multifunctional RNA nanoparticles. Nano Lett (2014) 1.03
Knockout mice in understanding the mechanism of action of lithium. Biochem Soc Trans (2009) 1.02
Limited transfer of cytosolic NADH into mitochondria at high cardiac workload. Am J Physiol Heart Circ Physiol (2004) 1.02
Apoptosis predominates in nonmyocytes in heart failure. Am J Physiol Heart Circ Physiol (2009) 1.02
Search for a common mechanism of mood stabilizers. Biochem Pharmacol (2003) 1.02
Differential roles of Epac in regulating cell death in neuronal and myocardial cells. J Biol Chem (2010) 1.02
Balancing GRK2 and EPAC1 levels prevents and relieves chronic pain. J Clin Invest (2013) 1.02
Homozygote inositol transporter knockout mice show a lithium-like phenotype. Bipolar Disord (2008) 1.00
Comparative analysis of mRNA isoform expression in cardiac hypertrophy and development reveals multiple post-transcriptional regulatory modules. PLoS One (2011) 0.99