Published in EMBO J on November 26, 2009
Rab GEFs and GAPs. Curr Opin Cell Biol (2010) 2.73
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway. Nat Cell Biol (2012) 1.88
Synchronization of secretory protein traffic in populations of cells. Nat Methods (2012) 1.41
C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking. Mol Biol Cell (2011) 1.37
Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. J Biol Chem (2012) 1.32
Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafish. Hepatology (2011) 1.21
ERK7 is a negative regulator of protein secretion in response to amino-acid starvation by modulating Sec16 membrane association. EMBO J (2011) 1.13
Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. Am J Hum Genet (2013) 1.03
Augmented annotation of the Schizosaccharomyces pombe genome reveals additional genes required for growth and viability. Genetics (2011) 1.01
A novel GTP-binding protein-adaptor protein complex responsible for export of Vangl2 from the trans Golgi network. Elife (2013) 1.00
Rab18 and a Rab18 GEF complex are required for normal ER structure. J Cell Biol (2014) 0.99
In vivo cell biology in zebrafish - providing insights into vertebrate development and disease. J Cell Sci (2014) 0.93
Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila. Development (2012) 0.93
Reduced cholesterol and triglycerides in mice with a mutation in Mia2, a liver protein that localizes to ER exit sites. J Lipid Res (2011) 0.92
The ALS8 protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendrites. EMBO J (2013) 0.88
Functional characterisation of the YIPF protein family in mammalian cells. Histochem Cell Biol (2016) 0.87
Studying non-alcoholic fatty liver disease with zebrafish: a confluence of optics, genetics, and physiology. Cell Mol Life Sci (2012) 0.85
Identification of ER proteins involved in the functional organisation of the early secretory pathway in Drosophila cells by a targeted RNAi screen. PLoS One (2011) 0.85
Tango1 spatially organizes ER exit sites to control ER export. J Cell Biol (2017) 0.83
The Arf family G protein Arl1 is required for secretory granule biogenesis in Drosophila. J Cell Sci (2014) 0.83
Live-cell assays to identify regulators of ER-to-Golgi trafficking. Traffic (2012) 0.82
Congenital muscular dystrophy with fatty liver and infantile-onset cataract caused by TRAPPC11 mutations: broadening of the phenotype. Skelet Muscle (2015) 0.81
TRAPP Complexes in Secretion and Autophagy. Front Cell Dev Biol (2016) 0.81
A genome-wide RNAi screen identifies regulators of cholesterol-modified hedgehog secretion in Drosophila. PLoS One (2012) 0.80
A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-κB (NF-κB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion. J Biol Chem (2014) 0.79
BRITER: a BMP responsive osteoblast reporter cell line. PLoS One (2012) 0.78
The clathrin adaptor AP-1 complex and Arf1 regulate planar cell polarity in vivo. Nat Commun (2015) 0.77
Active JNK-dependent secretion of Drosophila Tyrosyl-tRNA synthetase by loser cells recruits haemocytes during cell competition. Nat Commun (2015) 0.77
An antibody toolkit for the study of membrane traffic in Drosophila melanogaster. Biol Open (2016) 0.77
Ligand-independent requirements of steroid receptors EcR and USP for cell survival. Cell Death Differ (2015) 0.77
trappc11 is required for protein glycosylation in zebrafish and humans. Mol Biol Cell (2016) 0.76
Endocytosis of Wingless via a dynamin-independent pathway is necessary for signaling in Drosophila wing discs. Proc Natl Acad Sci U S A (2016) 0.75
TFG facilitates outer coat disassembly on COPII transport carriers to promote tethering and fusion with ER-Golgi intermediate compartments. Proc Natl Acad Sci U S A (2017) 0.75
Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature (2002) 45.19
Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell (1980) 23.17
Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron (1999) 17.62
Reconstitution of the transport of protein between successive compartments of the Golgi measured by the coupled incorporation of N-acetylglucosamine. Cell (1984) 10.74
The molecular motor toolbox for intracellular transport. Cell (2003) 9.97
TreeFam: a curated database of phylogenetic trees of animal gene families. Nucleic Acids Res (2006) 8.83
The mechanisms of vesicle budding and fusion. Cell (2004) 7.96
Clathrin-mediated endocytosis in AP-2-depleted cells. J Cell Biol (2003) 6.35
Bi-directional protein transport between the ER and Golgi. Annu Rev Cell Dev Biol (2004) 6.10
The staufen/pumilio pathway is involved in Drosophila long-term memory. Curr Biol (2003) 4.82
Coats, tethers, Rabs, and SNAREs work together to mediate the intracellular destination of a transport vesicle. Dev Cell (2007) 4.26
Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila. Mol Cell (2006) 3.98
Membrane fusion. Nat Struct Mol Biol (2008) 3.79
Functional genomics reveals genes involved in protein secretion and Golgi organization. Nature (2006) 3.72
Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. Cell (2005) 3.66
The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells. Mol Biol Cell (2008) 3.57
TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion. EMBO J (1998) 3.49
Prevalence of off-target effects in Drosophila RNA interference screens. Nature (2006) 3.38
Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression. Science (2007) 3.36
Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays. Nat Methods (2006) 3.29
TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism. Nature (2006) 3.04
Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae. Genome Res (2006) 2.81
Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins. J Cell Biol (2004) 2.76
Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum. Science (2000) 2.70
TANGO1 facilitates cargo loading at endoplasmic reticulum exit sites. Cell (2009) 2.58
The yeast v-SNARE Vti1p mediates two vesicle transport pathways through interactions with the t-SNAREs Sed5p and Pep12p. J Cell Biol (1997) 2.50
A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila. PLoS Biol (2008) 2.43
Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells. J Cell Sci (2007) 2.18
A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease. Development (2005) 2.12
SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis. Mol Biol Cell (2005) 2.08
The pleckstrin homology domain of oxysterol-binding protein recognises a determinant specific to Golgi membranes. Curr Biol (1998) 1.98
A systems biology analysis of the Drosophila phagosome. Nature (2006) 1.95
Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins. J Cell Biol (2008) 1.86
Membrane traffic within the Golgi apparatus. Annu Rev Cell Dev Biol (2009) 1.78
TAO kinases mediate activation of p38 in response to DNA damage. EMBO J (2007) 1.59
Characterization of a novel yeast SNARE protein implicated in Golgi retrograde traffic. Mol Biol Cell (1997) 1.54
Drosophila Sec16 mediates the biogenesis of tER sites upstream of Sar1 through an arginine-rich motif. Mol Biol Cell (2008) 1.49
The Drosophila Cog5 homologue is required for cytokinesis, cell elongation, and assembly of specialized Golgi architecture during spermatogenesis. Mol Biol Cell (2003) 1.46
The TRAPP complex: insights into its architecture and function. Traffic (2008) 1.40
CIF-1, a shared subunit of the COP9/signalosome and eukaryotic initiation factor 3 complexes, regulates MEL-26 levels in the Caenorhabditis elegans embryo. Mol Cell Biol (2007) 1.38
Syntaxin 5 is required for cytokinesis and spermatid differentiation in Drosophila. Dev Biol (2002) 1.37
TBC1D20 is a Rab1 GTPase-activating protein that mediates hepatitis C virus replication. J Biol Chem (2007) 1.36
Orchestrating organelle inheritance in Saccharomyces cerevisiae. Curr Opin Microbiol (2007) 1.23
Structure of melanoma inhibitory activity protein, a member of a recently identified family of secreted proteins. Proc Natl Acad Sci U S A (2001) 1.22
Mechanisms of transport through the Golgi complex. J Cell Sci (2009) 1.21
SNX18 is an SNX9 paralog that acts as a membrane tubulator in AP-1-positive endosomal trafficking. J Cell Sci (2008) 1.16
Early postnatal pulmonary failure and primary hypothyroidism in mice with combined TPST-1 and TPST-2 deficiency. Gen Comp Endocrinol (2007) 1.16
The extracellular human melanoma inhibitory activity (MIA) protein adopts an SH3 domain-like fold. EMBO J (2001) 1.01
Tvp38, Tvp23, Tvp18 and Tvp15: novel membrane proteins in the Tlg2-containing Golgi/endosome compartments of Saccharomyces cerevisiae. Exp Cell Res (2006) 0.92
The novel sorting nexin SNX33 interferes with cellular PrP formation by modulation of PrP shedding. Traffic (2008) 0.86
Extracellular SH3 domain containing proteins--features of a new protein family. Curr Protein Pept Sci (2008) 0.84
TVP23 interacts genetically with the yeast SNARE VTI1 and functions in retrograde transport from the early endosome to the late Golgi. Biochem J (2009) 0.82
Global mapping of the yeast genetic interaction network. Science (2004) 21.34
The small G proteins of the Arf family and their regulators. Annu Rev Cell Dev Biol (2007) 4.14
α-Synuclein impairs macroautophagy: implications for Parkinson's disease. J Cell Biol (2010) 3.67
Organelle identity and the signposts for membrane traffic. Nature (2005) 3.36
Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components. Curr Biol (2002) 3.23
Vesicle tethering complexes in membrane traffic. J Cell Sci (2002) 3.17
The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis. Mol Biol Cell (2004) 2.71
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell (2005) 2.56
ESCRTs and Fab1 regulate distinct steps of autophagy. Curr Biol (2007) 2.46
Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex. Nat Cell Biol (2008) 2.38
Targeting of the Arf-like GTPase Arl3p to the Golgi requires N-terminal acetylation and the membrane protein Sys1p. Nat Cell Biol (2004) 2.37
A comprehensive comparison of transmembrane domains reveals organelle-specific properties. Cell (2010) 2.35
Characterization of the interface between normal and transformed epithelial cells. Nat Cell Biol (2009) 2.21
The ARF-like GTPases Arl1p and Arl3p act in a pathway that interacts with vesicle-tethering factors at the Golgi apparatus. Curr Biol (2003) 2.03
Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins. J Cell Biol (2006) 1.92
The Drosophila homolog of Aut1 is essential for autophagy and development. FEBS Lett (2003) 1.92
Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins. J Cell Biol (2008) 1.86
Molecular recognition by a binary code. J Mol Biol (2005) 1.85
MOESIN crosslinks actin and cell membrane in Drosophila oocytes and is required for OSKAR anchoring. Curr Biol (2002) 1.84
Hemese, a hemocyte-specific transmembrane protein, affects the cellular immune response in Drosophila. Proc Natl Acad Sci U S A (2003) 1.79
An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility. J Cell Sci (2006) 1.71
Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus. Mol Cell (2003) 1.70
Multiple protein phosphatases are required for mitosis in Drosophila. Curr Biol (2007) 1.68
Rab14 is involved in membrane trafficking between the Golgi complex and endosomes. Mol Biol Cell (2004) 1.68
The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. Cell (2011) 1.66
Specific GATA factors act as conserved inducers of an endodermal-EMT. Dev Cell (2011) 1.64
A systematic approach to pair secretory cargo receptors with their cargo suggests a mechanism for cargo selection by Erv14. PLoS Biol (2012) 1.63
Long coiled-coil proteins and membrane traffic. Biochim Biophys Acta (2003) 1.61
Membrane delivery to the yeast autophagosome from the Golgi-endosomal system. Mol Biol Cell (2010) 1.61
Molecular characterization of Rab11 interactions with members of the family of Rab11-interacting proteins. J Biol Chem (2004) 1.56
A fluorescent reporter of caspase activity for live imaging. Proc Natl Acad Sci U S A (2008) 1.55
Accelerated homologous recombination and subsequent genome modification in Drosophila. Development (2013) 1.55
Endocytosis: a positive or a negative influence on Wnt signalling? Traffic (2007) 1.46
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. J Biol Chem (2008) 1.45
The endo-lysosomal sorting machinery interacts with the intermediate filament cytoskeleton. Mol Biol Cell (2004) 1.42
The yeast orthologue of GRASP65 forms a complex with a coiled-coil protein that contributes to ER to Golgi traffic. J Cell Biol (2007) 1.42
Arl8 and SKIP act together to link lysosomes to kinesin-1. Dev Cell (2011) 1.37
Spatial and functional relationship of GGAs and AP-1 in Drosophila and HeLa cells. Traffic (2009) 1.33
A targeted siRNA screen to identify SNAREs required for constitutive secretion in mammalian cells. Traffic (2010) 1.32
Segment boundary formation in Drosophila embryos. Development (2003) 1.30
Mistargeting of SH3TC2 away from the recycling endosome causes Charcot-Marie-Tooth disease type 4C. Hum Mol Genet (2009) 1.29
Glypicans shunt the Wingless signal between local signalling and further transport. Development (2005) 1.27
The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane. Curr Biol (2007) 1.27
Distinct and overlapping roles for AP-1 and GGAs revealed by the "knocksideways" system. Curr Biol (2012) 1.27
CASP, the alternatively spliced product of the gene encoding the CCAAT-displacement protein transcription factor, is a Golgi membrane protein related to giantin. Mol Biol Cell (2002) 1.23
Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex. J Cell Sci (2011) 1.23
Oriented cell divisions in the extending germband of Drosophila. Development (2007) 1.21
Untangling the evolution of Rab G proteins: implications of a comprehensive genomic analysis. BMC Biol (2012) 1.21
The GTPase Arf1p and the ER to Golgi cargo receptor Erv14p cooperate to recruit the golgin Rud3p to the cis-Golgi. J Cell Biol (2004) 1.21
Interpretation of the wingless gradient requires signaling-induced self-inhibition. Cell (2009) 1.21
Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Plant Physiol (2012) 1.20
Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs. Development (2005) 1.19
Producing cells retain and recycle Wingless in Drosophila embryos. Curr Biol (2002) 1.18
Death-receptor activation halts clathrin-dependent endocytosis. Proc Natl Acad Sci U S A (2006) 1.18
Sdmg1 is a conserved transmembrane protein associated with germ cell sex determination and germline-soma interactions in mice. Development (2008) 1.17
Selective export of HLA-F by its cytoplasmic tail. J Immunol (2006) 1.15
Evolution of specificity in the eukaryotic endomembrane system. Int J Biochem Cell Biol (2008) 1.14
In vivo role of lipid adducts on Wingless. J Cell Sci (2008) 1.14
Transport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex. Proc Natl Acad Sci U S A (2008) 1.13
Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane. Mol Biol Cell (2010) 1.09
The small G protein Arl1 directs the trans-Golgi-specific targeting of the Arf1 exchange factors BIG1 and BIG2. J Cell Biol (2012) 1.08
Requirements for transcriptional repression and activation by Engrailed in Drosophila embryos. Development (2003) 1.07
The exocyst component Sec5 is present on endocytic vesicles in the oocyte of Drosophila melanogaster. J Cell Biol (2005) 1.07
Wingless promotes proliferative growth in a gradient-independent manner. Sci Signal (2009) 1.07
Cancer becomes wasteful: emerging roles of exosomes(†) in cell-fate determination. J Extracell Vesicles (2013) 1.04
Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells. J Cell Sci (2013) 1.04
Drosophila S2 cells secrete wingless on exosome-like vesicles but the wingless gradient forms independently of exosomes. Traffic (2012) 1.03
A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress. Mol Cell (2013) 1.02
Integration of morphogen signalling within the growth regulatory network. Curr Opin Cell Biol (2012) 1.00
Modulation of developmental signals by endocytosis: different means and many ends. Curr Opin Cell Biol (2003) 1.00
The components of the Saccharomyces cerevisiae mannosyltransferase complex M-Pol I have distinct functions in mannan synthesis. J Biol Chem (2002) 0.98
Coiled-coil interactions are required for post-Golgi R-SNARE trafficking. EMBO Rep (2009) 0.98
More than one way to replicate the Golgi apparatus. Nat Cell Biol (2002) 0.96
Structural basis of the intracellular sorting of the SNARE VAMP7 by the AP3 adaptor complex. Dev Cell (2012) 0.96
Glypican-mediated endocytosis of Hedgehog has opposite effects in flies and mice. Trends Cell Biol (2008) 0.95
Disruption of Vps4 and JNK function in Drosophila causes tumour growth. PLoS One (2009) 0.94
An Arabidopsis GRIP domain protein locates to the trans-Golgi and binds the small GTPase ARL1. Plant J (2005) 0.92
Cell biology: earthworms and lipid couriers. Nature (2003) 0.90
Conserved and divergent elements in Torso RTK activation in Drosophila development. Sci Rep (2012) 0.90
Insulin-stimulated cytosol alkalinization facilitates optimal activation of glucose transport in cardiomyocytes. Am J Physiol Endocrinol Metab (2002) 0.89
Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus. J Biol Chem (2005) 0.89
How does cholesterol affect the way Hedgehog works? Development (2006) 0.88
An N-acetylglucosaminyltransferase of the Golgi apparatus of the yeast Saccharomyces cerevisiae that can modify N-linked glycans. Glycobiology (2003) 0.87
Class I FIPs, Rab11-binding proteins that regulate endocytic sorting and recycling. Methods Enzymol (2005) 0.87
Uncoupling the functions of CALM in VAMP sorting and clathrin-coated pit formation. PLoS One (2013) 0.87
FIP1/RCP binding to Golgin-97 regulates retrograde transport from recycling endosomes to the trans-Golgi network. Mol Biol Cell (2010) 0.87
An efficient promoter trap for detection of patterned gene expression and subsequent functional analysis in Drosophila. Proc Natl Acad Sci U S A (2006) 0.85
Identification of a guanine nucleotide exchange factor for Arf3, the yeast orthologue of mammalian Arf6. PLoS One (2007) 0.85
Autolytic activation and localization in Schneider cells (S2) of calpain B from Drosophila. Biochem J (2004) 0.85
Molecular cloning and RNA expression of a novel Drosophila calpain, Calpain C. Biochem Biophys Res Commun (2003) 0.80
Hedgehog threads to spread. Nat Cell Biol (2013) 0.79
Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis. Mol Biol Cell (2013) 0.79
Apical deficiency triggers JNK-dependent apoptosis in the embryonic epidermis of Drosophila. Development (2011) 0.79