Published in J Am Soc Nephrol on December 03, 2009
Lower urinary connective tissue growth factor levels and incident CKD stage 3 in the general population. Am J Kidney Dis (2011) 1.88
Genetics of kidney failure and the evolving story of APOL1. J Clin Invest (2011) 1.69
UMOD as a susceptibility gene for end-stage renal disease. BMC Med Genet (2012) 1.06
Common variants in UMOD associate with urinary uromodulin levels: a meta-analysis. J Am Soc Nephrol (2014) 1.06
Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel. PLoS One (2013) 1.06
Uromodulin in kidney injury: an instigator, bystander, or protector? Am J Kidney Dis (2012) 1.00
Genome-wide association studies of chronic kidney disease: what have we learned? Nat Rev Nephrol (2011) 0.98
Novel urinary protein biomarkers predicting the development of microalbuminuria and renal function decline in type 1 diabetes. Diabetes Care (2012) 0.96
Urinary uromodulin, kidney function, and cardiovascular disease in elderly adults. Kidney Int (2015) 0.91
Association between genotype and phenotype in uromodulin-associated kidney disease. Clin J Am Soc Nephrol (2013) 0.90
Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing. PLoS One (2012) 0.89
Clinical, Genetic, and Urinary Factors Associated with Uromodulin Excretion. Clin J Am Soc Nephrol (2015) 0.85
Biomarkers for incident CKD: a new framework for interpreting the literature. Nat Rev Nephrol (2013) 0.85
Uromodulin concentrations are not associated with incident CKD among persons with coronary artery disease. BMC Nephrol (2011) 0.85
Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis. J Am Soc Nephrol (2015) 0.83
Uromodulin and translational medicine: will the SNPs bring zip to clinical practice? J Am Soc Nephrol (2010) 0.83
Molecular and cellular effects of Tamm-Horsfall protein mutations and their rescue by chemical chaperones. J Biol Chem (2011) 0.81
Study design of DIACORE (DIAbetes COhoRtE) - a cohort study of patients with diabetes mellitus type 2. BMC Med Genet (2013) 0.80
Associations of Urinary Uromodulin with Clinical Characteristics and Markers of Tubular Function in the General Population. Clin J Am Soc Nephrol (2015) 0.80
Insights into kidney diseases from genome-wide association studies. Nat Rev Nephrol (2016) 0.79
Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study. BMC Med Genet (2011) 0.79
Genetic susceptibility to hypertensive renal disease. Cell Mol Life Sci (2012) 0.78
From juvenile hyperuricaemia to dysfunctional uromodulin: an ongoing metamorphosis. Pediatr Nephrol (2016) 0.76
Uromodulin, kidney function, cardiovascular disease, and mortality. Kidney Int (2015) 0.75
Genetic Considerations in Pediatric Chronic Kidney Disease. J Pediatr Genet (2015) 0.75
Variable presentations of rare genetic renal interstitial diseases. Clin J Am Soc Nephrol (2014) 0.75
Mendelian and trans-generational inheritance in hypertensive renal disease. Ann Med (2012) 0.75
Genome-wide association studies and contribution to cardiovascular physiology. Physiol Genomics (2015) 0.75
Functional analysis of UMOD gene and its effect on inflammatory cytokines in serum of essential hypertension patients. Int J Clin Exp Pathol (2015) 0.75
Characterization of a recurrent in-frame UMOD indel mutation causing late-onset autosomal dominant end-stage renal failure. Clin J Am Soc Nephrol (2011) 0.75
A Perspective on Chronic Kidney Disease Progression. Am J Physiol Renal Physiol (2016) 0.75
Uromodulin: from physiology to rare and complex kidney disorders. Nat Rev Nephrol (2017) 0.75
Development of next generation sequencing panel for UMOD and association with kidney disease. PLoS One (2017) 0.75
A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med (1999) 82.86
K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis (2002) 81.62
Prevalence of chronic kidney disease in the United States. JAMA (2007) 38.98
The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators. Am J Epidemiol (1989) 37.83
An investigation of coronary heart disease in families. The Framingham offspring study. Am J Epidemiol (1979) 18.84
Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies. J Am Soc Nephrol (2004) 8.21
Predictors of new-onset kidney disease in a community-based population. JAMA (2004) 7.45
Calibration and random variation of the serum creatinine assay as critical elements of using equations to estimate glomerular filtration rate. Am J Kidney Dis (2002) 7.03
Characterization and separation of an inhibitor of viral hemagglutination present in urine. Proc Soc Exp Biol Med (1950) 4.86
Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet (2009) 4.78
Prevalence of chronic kidney disease in population-based studies: systematic review. BMC Public Health (2008) 4.49
Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy. J Med Genet (2002) 2.90
Tamm-Horsfall glycoprotein: biology and clinical relevance. Am J Kidney Dis (2003) 2.59
Allelism of MCKD, FJHN and GCKD caused by impairment of uromodulin export dynamics. Hum Mol Genet (2003) 2.01
Familial clustering of chronic kidney disease. Semin Dial (2007) 1.95
Identifying patients with chronic kidney disease from general practice computer records. Fam Pract (2005) 1.86
A cluster of mutations in the UMOD gene causes familial juvenile hyperuricemic nephropathy with abnormal expression of uromodulin. J Am Soc Nephrol (2003) 1.77
Alterations of uromodulin biology: a common denominator of the genetically heterogeneous FJHN/MCKD syndrome. Kidney Int (2006) 1.65
Uromodulin: a unique 85-kilodalton immunosuppressive glycoprotein isolated from urine of pregnant women. Science (1985) 1.60
Defective intracellular trafficking of uromodulin mutant isoforms. Traffic (2006) 1.31
Uromodulin mutations causing familial juvenile hyperuricaemic nephropathy lead to protein maturation defects and retention in the endoplasmic reticulum. Hum Mol Genet (2009) 1.24
A robust, streamlined, and reproducible method for proteomic analysis of serum by delipidation, albumin and IgG depletion, and two-dimensional gel electrophoresis. Proteomics (2005) 1.18
Mutations in the uromodulin gene decrease urinary excretion of Tamm-Horsfall protein. Kidney Int (2004) 1.16
Human Tamm-Horsfall glycoprotein: urinary and plasma levels in normal subjects and patients with renal disease determined by a fully validated radioimmunoassay. Clin Sci (Lond) (1985) 1.01
An improved radioimmunoassay for urinary Tamm-Horsfall glycoprotein. Investigation and resolution of factors affecting its quantification. Biochem J (1982) 0.98
Factors affecting excretion of human urinary Tamm-Horsfall glycoprotein. Clin Sci (Lond) (1982) 0.94
Uromodulin and Tamm-Horsfall protein induce human monocytes to secrete TNF and express tissue factor. J Immunol (1997) 0.93
Proteomic alterations in heat shock protein 27 and identification of phosphoproteins in ascending aortic aneurysm associated with bicuspid and tricuspid aortic valve. J Mol Cell Cardiol (2007) 0.90
Conditions for solubilization of Tamm-Horsfall protein/uromodulin in human urine and establishment of a sensitive and accurate enzyme-linked immunosorbent assay (ELISA) method. Arch Biochem Biophys (2001) 0.89
A new equation to estimate glomerular filtration rate. Ann Intern Med (2009) 71.41
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 56.72
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 41.47
Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med (2006) 32.81
Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98
Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79
Heart disease and stroke statistics--2011 update: a report from the American Heart Association. Circulation (2010) 30.07
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 26.95
National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med (2003) 23.33
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Heart disease and stroke statistics--2015 update: a report from the American Heart Association. Circulation (2014) 22.74
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Assessing kidney function--measured and estimated glomerular filtration rate. N Engl J Med (2006) 20.27
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet (2006) 19.03
Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet (2010) 18.36
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2013) 17.18
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol (2002) 16.25
Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med (2006) 16.17
Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med (2006) 15.60
C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med (2004) 15.30
Estimating GFR using serum cystatin C alone and in combination with serum creatinine: a pooled analysis of 3,418 individuals with CKD. Am J Kidney Dis (2008) 15.04
Estimating glomerular filtration rate from serum creatinine and cystatin C. N Engl J Med (2012) 14.99
Expressing the Modification of Diet in Renal Disease Study equation for estimating glomerular filtration rate with standardized serum creatinine values. Clin Chem (2007) 13.80
Vitamin D deficiency and risk of cardiovascular disease. Circulation (2008) 13.39
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature (2009) 13.28
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet (2007) 13.28
Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults. N Engl J Med (2010) 13.25
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Obesity and the risk of heart failure. N Engl J Med (2002) 12.58
Metabolite profiles and the risk of developing diabetes. Nat Med (2011) 12.22
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Common values in assessing health outcomes from disease and injury: disability weights measurement study for the Global Burden of Disease Study 2010. Lancet (2012) 11.32
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
The state of US health, 1990-2010: burden of diseases, injuries, and risk factors. JAMA (2013) 10.43
Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int (2005) 10.42
Long-term trends in the incidence of and survival with heart failure. N Engl J Med (2002) 10.37
2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation (2013) 10.24
Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation (2015) 10.14
The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination. Am J Epidemiol (2007) 9.90
Genotype score in addition to common risk factors for prediction of type 2 diabetes. N Engl J Med (2008) 9.68
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Nat Genet (2008) 9.50
The definition, classification, and prognosis of chronic kidney disease: a KDIGO Controversies Conference report. Kidney Int (2010) 9.25
Arterial stiffness and cardiovascular events: the Framingham Heart Study. Circulation (2010) 9.09
Recommendations for improving serum creatinine measurement: a report from the Laboratory Working Group of the National Kidney Disease Education Program. Clin Chem (2005) 8.93
2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2013) 8.90
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89