Published in Nat Genet on May 10, 2009
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
A genome-wide perspective of genetic variation in human metabolism. Nat Genet (2009) 5.00
Genetic loci influencing kidney function and chronic kidney disease. Nat Genet (2010) 3.75
Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies. Int J Epidemiol (2012) 3.62
The Rotterdam Study: 2010 objectives and design update. Eur J Epidemiol (2009) 3.44
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CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
The Rotterdam Study: 2014 objectives and design update. Eur J Epidemiol (2013) 2.56
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy. Nature (2013) 2.46
Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression. Nat Med (2013) 2.28
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. Nat Genet (2011) 2.27
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet (2010) 2.24
Uromodulin levels associate with a common UMOD variant and risk for incident CKD. J Am Soc Nephrol (2009) 2.10
Common genetic variants of the human uromodulin gene regulate transcription and predict plasma uric acid levels. Kidney Int (2013) 2.05
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet (2012) 2.05
Integrative urinary peptidomics in renal transplantation identifies biomarkers for acute rejection. J Am Soc Nephrol (2010) 2.00
A genome-wide association study for diabetic nephropathy genes in African Americans. Kidney Int (2010) 1.98
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Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels. PLoS Genet (2010) 1.91
New susceptibility loci associated with kidney disease in type 1 diabetes. PLoS Genet (2012) 1.79
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Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet (2012) 1.68
Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD. PLoS Genet (2011) 1.68
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Genetic association for renal traits among participants of African ancestry reveals new loci for renal function. PLoS Genet (2011) 1.60
Emerging risk factors and markers of chronic kidney disease progression. Nat Rev Nephrol (2009) 1.58
Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans. PLoS Genet (2011) 1.57
Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases. PLoS Genet (2010) 1.57
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The Uromodulin Gene Locus Shows Evidence of Pathogen Adaptation through Human Evolution. J Am Soc Nephrol (2016) 1.41
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Uromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expression. Hum Mol Genet (2010) 1.10
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UMOD as a susceptibility gene for end-stage renal disease. BMC Med Genet (2012) 1.06
Integrating human and rodent data to identify the genetic factors involved in chronic kidney disease. J Am Soc Nephrol (2010) 1.06
Common variants in UMOD associate with urinary uromodulin levels: a meta-analysis. J Am Soc Nephrol (2014) 1.06
Systems biology of kidney diseases. Kidney Int (2011) 1.05
Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function. J Biol Chem (2010) 1.04
Risk factors for progression of chronic kidney disease. Curr Opin Pediatr (2010) 1.03
Association of functional polymorphism rs2231142 (Q141K) in the ABCG2 gene with serum uric acid and gout in 4 US populations: the PAGE Study. Am J Epidemiol (2013) 1.03
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A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level. BMC Med Genet (2010) 1.00
Genome-wide association studies of chronic kidney disease: what have we learned? Nat Rev Nephrol (2011) 0.98
Performance of a genetic risk score for CKD stage 3 in the general population. Am J Kidney Dis (2011) 0.96
Novel urinary protein biomarkers predicting the development of microalbuminuria and renal function decline in type 1 diabetes. Diabetes Care (2012) 0.96
Consent for genetic research in the Framingham Heart Study. Am J Med Genet A (2010) 0.96
Validated SNPs for eGFR and their associations with albuminuria. Hum Mol Genet (2012) 0.95
Population ancestry and genetic risk for diabetes and kidney, cardiovascular, and bone disease: modifiable environmental factors may produce the cures. Am J Kidney Dis (2013) 0.93
A risk score for chronic kidney disease in the general population. Am J Med (2012) 0.93
A susceptibility gene for kidney disease in an obese mouse model of type II diabetes maps to chromosome 8. Kidney Int (2010) 0.92
Genome-wide association study of kidney function decline in individuals of European descent. Kidney Int (2014) 0.91
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Urinary uromodulin, kidney function, and cardiovascular disease in elderly adults. Kidney Int (2015) 0.91
Epigenomics: the science of no-longer-junk DNA. Why study it in chronic kidney disease? Semin Nephrol (2013) 0.90
Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis. J Clin Invest (2014) 0.89
Prevalence of CKD and its relationship to eGFR-related genetic loci and clinical risk factors in the SardiNIA study cohort. J Am Soc Nephrol (2014) 0.89
Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing. PLoS One (2012) 0.89
Heterogeneous stock rats: a new model to study the genetics of renal phenotypes. Am J Physiol Renal Physiol (2010) 0.89
The Gly(972)Arg variant of human IRS1 gene is associated with variation in glomerular filtration rate likely through impaired insulin receptor signaling. Diabetes (2012) 0.89
Genetic basis of nondiabetic end-stage renal disease. Semin Nephrol (2010) 0.89
Susceptibility genes in common complex kidney disease. Curr Opin Nephrol Hypertens (2010) 0.89
The natural history of, and risk factors for, progressive chronic kidney disease (CKD): the Renal Impairment in Secondary care (RIISC) study; rationale and protocol. BMC Nephrol (2013) 0.87
Urinary uromodulin excretion predicts progression of chronic kidney disease resulting from IgA nephropathy. PLoS One (2013) 0.87
SNP prioritization using a Bayesian probability of association. Genet Epidemiol (2012) 0.86
Homoarginine and progression of chronic kidney disease: results from the Mild to Moderate Kidney Disease Study. PLoS One (2013) 0.86
Epigenetics of progression of chronic kidney disease: fact or fantasy? Semin Nephrol (2013) 0.86
Clinical, Genetic, and Urinary Factors Associated with Uromodulin Excretion. Clin J Am Soc Nephrol (2015) 0.85
Development and validation of an electronic phenotyping algorithm for chronic kidney disease. AMIA Annu Symp Proc (2014) 0.85
Podocyte-actin dynamics in health and disease. Nat Rev Nephrol (2016) 0.85
Risk factors for chronic kidney disease: an update. Kidney Int Suppl (2011) (2013) 0.84
Genome-wide association studies and large-scale collaborations in epidemiology. Eur J Epidemiol (2010) 0.84
Investigation of known estimated glomerular filtration rate loci in patients with type 2 diabetes. Diabet Med (2013) 0.84
Tamm-Horsfall protein regulates circulating and renal cytokines by affecting glomerular filtration rate and acting as a urinary cytokine trap. J Biol Chem (2012) 0.84
Hypertensive renal disease: susceptibility and resistance in inbred hypertensive rat lines. J Hypertens (2013) 0.84
Hurdles to the introduction of new therapies for immune-mediated kidney diseases. Nat Rev Nephrol (2016) 0.84
Common charge-shift mutation Glu65Lys in K+ channel β₁-Subunit KCNMB1: pleiotropic consequences for glomerular filtration rate and progressive renal disease. Am J Nephrol (2010) 0.83
SORCS1 contributes to the development of renal disease in rats and humans. Physiol Genomics (2013) 0.83
Genetics, ancestry, and hypertension: implications for targeted antihypertensive therapies. Curr Hypertens Rep (2014) 0.83
Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis. J Am Soc Nephrol (2015) 0.83
Disease progression subtype discovery from longitudinal EMR data with a majority of missing values and unknown initial time points. AMIA Annu Symp Proc (2014) 0.83
Multiple loci associated with renal function in African Americans. PLoS One (2012) 0.83
Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations. BMC Genet (2014) 0.83
Top Three Pharmacogenomics and Personalized Medicine Applications at the Nexus of Renal Pathophysiology and Cardiovascular Medicine. Curr Pharmacogenomics Person Med (2011) 0.83
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Estimating GFR using serum cystatin C alone and in combination with serum creatinine: a pooled analysis of 3,418 individuals with CKD. Am J Kidney Dis (2008) 15.04
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