CTLA4Ig alters the course of autoimmune disease development in Lyn-/- mice.

PubWeight™: 0.85‹?›

🔗 View Article (PMID 19966213)

Published in J Immunol on December 04, 2009

Authors

Sarah A Oracki1, Evelyn Tsantikos, Cathy Quilici, Amanda Light, Thomas Schmidt, Andrew M Lew, Joanne E Martin, Ken G Smith, Margaret L Hibbs, David M Tarlinton

Author Affiliations

1: Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

Articles by these authors

Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA (2005) 9.81

Migratory dendritic cells transfer antigen to a lymph node-resident dendritic cell population for efficient CTL priming. Immunity (2006) 5.32

Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science (2003) 4.40

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism. J Exp Med (2010) 4.04

FcgammaRIIb controls bone marrow plasma cell persistence and apoptosis. Nat Immunol (2007) 3.04

Percutaneous implantation of the CoreValve self-expanding valve prosthesis in high-risk patients with aortic valve disease: the Siegburg first-in-man study. Circulation (2006) 2.88

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement. Blood (2008) 2.83

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells. J Exp Med (2003) 2.77

Plasma cell ontogeny defined by quantitative changes in blimp-1 expression. J Exp Med (2004) 2.76

Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells. Blood (2006) 2.72

Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell (2013) 2.64

Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1. Immunity (2007) 2.61

Robust cell polarity is a dynamic state established by coupling transport and GTPase signaling. J Cell Biol (2004) 2.56

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis. Nature (2009) 2.54

Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization. J Exp Med (2005) 2.51

Differential development of murine dendritic cells by GM-CSF versus Flt3 ligand has implications for inflammation and trafficking. J Immunol (2007) 2.43

Mcl-1 is essential for germinal center formation and B cell memory. Science (2010) 2.42

Inflammatory skin and bowel disease linked to ADAM17 deletion. N Engl J Med (2011) 2.41

Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease. Cell (2010) 2.26

NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation. J Immunol (2007) 2.26

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse. Nat Immunol (2012) 2.14

Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation. Nat Immunol (2003) 2.11

Regulation of angiogenesis by oxygen and metabolism. Dev Cell (2009) 2.04

Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6. Blood (2009) 2.01

Lyn tyrosine kinase: accentuating the positive and the negative. Immunity (2005) 2.01

Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1. Nat Immunol (2007) 1.97

Germinal center B and follicular helper T cells: siblings, cousins or just good friends? Nat Immunol (2011) 1.95

Single-molecule imaging of the H-ras membrane-anchor reveals domains in the cytoplasmic leaflet of the cell membrane. Biophys J (2004) 1.95

Negative regulation of immunoglobulin E-dependent allergic responses by Lyn kinase. J Exp Med (2004) 1.91

The London Classification of gastrointestinal neuromuscular pathology: report on behalf of the Gastro 2009 International Working Group. Gut (2010) 1.89

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP. J Clin Invest (2006) 1.88

Selected Toll-like receptor ligands and viruses promote helper-independent cytotoxic T cell priming by upregulating CD40L on dendritic cells. Immunity (2009) 1.85

Infrahepatic inferior vena cava clamping for reduction of central venous pressure and blood loss during hepatic resection: a randomized controlled trial. Ann Surg (2011) 1.81

B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells. J Exp Med (2011) 1.78

Different time courses for visual perception and action priming. Proc Natl Acad Sci U S A (2003) 1.78

Memory B cells: effectors of long-lived immune responses. Eur J Immunol (2009) 1.74

Plasma cell development and survival. Immunol Rev (2010) 1.74

Mcl-1 is essential for the survival of plasma cells. Nat Immunol (2013) 1.73

Palladium-catalyzed decarboxylative asymmetric allylic alkylation of enol carbonates. J Am Chem Soc (2009) 1.72

The cell biology of cross-presentation and the role of dendritic cell subsets. Immunol Cell Biol (2008) 1.69

Plasma cell development: from B-cell subsets to long-term survival niches. Semin Immunol (2008) 1.68

B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1. J Exp Med (2012) 1.65

Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow. Blood (2010) 1.63

B-cell stage and context-dependent requirements for survival signals from BAFF and the B-cell receptor. Immunol Rev (2010) 1.54

Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates. Genes Cancer (2010) 1.54

Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset. Proc Natl Acad Sci U S A (2008) 1.53

Gastrointestinal neuromuscular pathology: guidelines for histological techniques and reporting on behalf of the Gastro 2009 International Working Group. Acta Neuropathol (2009) 1.48

Vascular endothelial growth factor D is dispensable for development of the lymphatic system. Mol Cell Biol (2005) 1.47

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets. Blood (2012) 1.46

Single-step Strep-tag purification for the isolation and identification of protein complexes from mammalian cells. Proteomics (2005) 1.45

DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome. Am J Hum Genet (2008) 1.45

CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers. Nat Immunol (2005) 1.43

Innate immune surveillance of spontaneous B cell lymphomas by natural killer cells and gammadelta T cells. J Exp Med (2004) 1.40

Common complications of cirrhosis: do we follow too often the 'Casablanca strategy'? Liver Int (2011) 1.39

Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease. J Exp Med (2008) 1.38

Use of Taxus polymer-coated paclitaxel-eluting stents for treatment of in-stent restenosis in real world patients: results of clinical and angiographic follow-up at six months in a single-center registry. Catheter Cardiovasc Interv (2006) 1.37

Characterization of an immediate splenic precursor of CD8+ dendritic cells capable of inducing antiviral T cell responses. J Immunol (2009) 1.37

A requirement for CD45 distinguishes Ly49D-mediated cytokine and chemokine production from killing in primary natural killer cells. J Exp Med (2005) 1.35

The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes. J Immunol (2002) 1.35

A novel mutation in the Nfkb2 gene generates an NF-kappa B2 "super repressor". J Immunol (2007) 1.34

Single-molecule diffusion measurements of H-Ras at the plasma membrane of live cells reveal microdomain localization upon activation. J Cell Sci (2005) 1.34

Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype. J Immunol (2011) 1.33

Basic amino-acid side chains regulate transmembrane integrin signalling. Nature (2011) 1.30

Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity. J Exp Med (2002) 1.29

Distinct macrophage subpopulations characterize acute infection and chronic inflammatory lung disease. J Immunol (2012) 1.28

Perturbed myelo/erythropoiesis in Lyn-deficient mice is similar to that in mice lacking the inhibitory phosphatases SHP-1 and SHIP-1. Blood (2004) 1.28

A role for Blimp1 in the transcriptional network controlling natural killer cell maturation. Blood (2010) 1.26

Contribution of claudin-5 to barrier properties in tight junctions of epithelial cells. Cell Tissue Res (2005) 1.26

Terrestrial pesticide exposure of amphibians: an underestimated cause of global decline? Sci Rep (2013) 1.26

The C-type lectin Clec12A present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses. J Immunol (2009) 1.25

SHIP1 and Lyn Kinase Negatively Regulate Integrin alpha IIb beta 3 signaling in platelets. J Biol Chem (2004) 1.25

Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2. FASEB J (2007) 1.24

Reversible HLA multimers (Streptamers) for the isolation of human cytotoxic T lymphocytes functionally active against tumor- and virus-derived antigens. J Immunol Methods (2007) 1.24

Antigen delivery via two molecules on the CD8- dendritic cell subset induces humoral immunity in the absence of conventional "danger". Eur J Immunol (2005) 1.23

Early postnatal death and motor disorders in mice congenitally deficient in calnexin expression. Mol Cell Biol (2002) 1.22

Novel phenotypes identified by plasma biochemical screening in the mouse. Mamm Genome (2002) 1.22

BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs. Proc Natl Acad Sci U S A (2010) 1.22

An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. Dis Model Mech (2009) 1.22

Proapoptotic BH3-only protein Bim is essential for developmentally programmed death of germinal center-derived memory B cells and antibody-forming cells. Blood (2007) 1.21

Determining germinal centre B cell fate. Trends Immunol (2012) 1.20

Deliberately provoking local inflammation drives tumors to become their own protective vaccine site. Int Immunol (2008) 1.19

"Antimyeloangiogenic" therapy for cancer by inhibiting PlGF. Clin Cancer Res (2009) 1.18

Loss of c-Cbl RING finger function results in high-intensity TCR signaling and thymic deletion. EMBO J (2005) 1.18

Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling. Proc Natl Acad Sci U S A (2004) 1.17

Accurate determination of elastic parameters for multicomponent membranes. Phys Rev Lett (2008) 1.16