Published in Neuropharmacology on December 24, 2009
Enhancement of attentional performance by selective stimulation of alpha4beta2(*) nAChRs: underlying cholinergic mechanisms. Neuropsychopharmacology (2010) 1.31
Nicotinic acetylcholine receptor ligands, a patent review (2006-2011). Expert Opin Ther Pat (2011) 0.84
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system. Nat Rev Drug Discov (2009) 3.26
BK potassium channels control transmitter release at CA3-CA3 synapses in the rat hippocampus. J Physiol (2004) 1.89
At immature mossy-fiber-CA3 synapses, correlated presynaptic and postsynaptic activity persistently enhances GABA release and network excitability via BDNF and cAMP-dependent PKA. J Neurosci (2009) 1.66
The GABA excitatory/inhibitory shift in brain maturation and neurological disorders. Neuroscientist (2012) 1.59
Alterations of GABAergic signaling in autism spectrum disorders. Neural Plast (2011) 1.56
Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis. Biol Psychiatry (2006) 1.53
GABA-mediated giant depolarizing potentials as coincidence detectors for enhancing synaptic efficacy in the developing hippocampus. Proc Natl Acad Sci U S A (2004) 1.49
Agomelatine, the first melatonergic antidepressant: discovery, characterization and development. Nat Rev Drug Discov (2010) 1.47
Enhancement of attentional performance by selective stimulation of alpha4beta2(*) nAChRs: underlying cholinergic mechanisms. Neuropsychopharmacology (2010) 1.31
Up-regulation of GLT-1 severely impairs LTD at mossy fibre--CA3 synapses. J Physiol (2009) 1.24
Post-phosphorylation prolyl isomerisation of gephyrin represents a mechanism to modulate glycine receptors function. EMBO J (2007) 1.20
'Deaf, mute and whispering' silent synapses: their role in synaptic plasticity. J Physiol (2004) 1.18
Nicotine activates immature "silent" connections in the developing hippocampus. Proc Natl Acad Sci U S A (2003) 1.17
Low expression of Kv7/M channels facilitates intrinsic and network bursting in the developing rat hippocampus. J Physiol (2008) 1.15
Nicotinic modulation of network and synaptic transmission in the immature hippocampus investigated with genetically modified mice. J Physiol (2006) 1.12
Refuting the challenges of the developmental shift of polarity of GABA actions: GABA more exciting than ever! Front Cell Neurosci (2012) 1.12
S 17092: a prolyl endopeptidase inhibitor as a potential therapeutic drug for memory impairment. Preclinical and clinical studies. CNS Drug Rev (2002) 1.08
GABAergic signaling at mossy fiber synapses in neonatal rat hippocampus. J Neurosci (2006) 1.05
GAT-1 regulates both tonic and phasic GABA(A) receptor-mediated inhibition in the cerebral cortex. J Neurochem (2008) 1.05
Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate. J Neurosci (2011) 1.05
Electrophysiological perspectives on the therapeutic use of nicotinic acetylcholine receptor partial agonists. J Pharmacol Exp Ther (2011) 1.03
Control of GABA Release at Mossy Fiber-CA3 Connections in the Developing Hippocampus. Front Synaptic Neurosci (2010) 1.01
Presynaptic source of quantal size variability at GABAergic synapses in rat hippocampal neurons in culture. Eur J Neurosci (2004) 1.01
Effect of agomelatine in the chronic mild stress model of depression in the rat. Neuropsychopharmacology (2002) 1.01
Behavioural and neuroplastic effects of the new-generation antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice. Int J Neuropsychopharmacol (2009) 1.01
Persistent decrease in synaptic efficacy induced by nicotine at Schaffer collateral-CA1 synapses in the immature rat hippocampus. J Physiol (2004) 1.00
Declusterization of GABAA receptors affects the kinetic properties of GABAergic currents in cultured hippocampal neurons. J Biol Chem (2003) 1.00
Frequency-dependent shift from paired-pulse facilitation to paired-pulse depression at unitary CA3-CA3 synapses in the rat hippocampus. J Physiol (2002) 0.98
The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats. Neuropharmacology (2009) 0.98
Correlated network activity enhances synaptic efficacy via BDNF and the ERK pathway at immature CA3 CA1 connections in the hippocampus. Proc Natl Acad Sci U S A (2007) 0.97
Role of giant depolarizing potentials in shaping synaptic currents in the developing hippocampus. Crit Rev Neurobiol (2006) 0.97
In the adult hippocampus, chronic nerve growth factor deprivation shifts GABAergic signaling from the hyperpolarizing to the depolarizing direction. J Neurosci (2010) 0.95
The partial alpha7 nicotine acetylcholine receptor agonist S 24795 enhances long-term potentiation at CA3-CA1 synapses in the adult mouse hippocampus. Neuropharmacology (2007) 0.94
S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. II. A neurochemical, electrophysiological and behavioral characterization in vivo. J Pharmacol Exp Ther (2007) 0.94
Partial agonist and neuromodulatory activity of S 24795 for alpha7 nAChR responses of hippocampal interneurons. Neuropharmacology (2007) 0.92
Nicotine-induced enhancement of synaptic plasticity at CA3-CA1 synapses requires GABAergic interneurons in adult anti-NGF mice. J Physiol (2006) 0.92
Design, synthesis, and pharmacology of novel 7-substituted 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors. J Med Chem (2007) 0.92
Pre-synaptic BK channels selectively control glutamate versus GABA release from cortical and hippocampal nerve terminals. J Neurochem (2010) 0.92
Antidepressant-like activity of S 20098 (agomelatine) in the forced swimming test in rodents: involvement of melatonin and serotonin receptors. J Psychiatry Neurosci (2004) 0.91
Spontaneous recurrent network activity in organotypic rat hippocampal slices. Eur J Neurosci (2005) 0.90
Antidepressant action of agomelatine (S 20098) in a transgenic mouse model. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.89
An ID-like current that is downregulated by Ca2+ modulates information coding at CA3-CA3 synapses in the rat hippocampus. J Physiol (2003) 0.89
Gephyrin regulates GABAergic and glutamatergic synaptic transmission in hippocampal cell cultures. J Biol Chem (2011) 0.89
Antidepressant-like effects of agomelatine (S 20098) in the learned helplessness model. Behav Pharmacol (2006) 0.89
Modulation of GABA-mediated Synaptic Potentials by Glutamatergic Agonists in Neonatal CA3 Rat Hippocampal Neurons. Eur J Neurosci (1991) 0.89
In the developing rat hippocampus a tonic GABAA-mediated conductance selectively enhances the glutamatergic drive of principal cells. J Physiol (2007) 0.89
Functional role of ambient GABA in refining neuronal circuits early in postnatal development. Front Neural Circuits (2013) 0.88
Nicotine blocks the hyperpolarization-activated current Ih and severely impairs the oscillatory behavior of oriens-lacunosum moleculare interneurons. J Neurosci (2010) 0.88
Clustering of extrasynaptic GABA(A) receptors modulates tonic inhibition in cultured hippocampal neurons. J Biol Chem (2004) 0.88
New fluorinated 1,2,4-benzothiadiazine 1,1-dioxides: discovery of an orally active cognitive enhancer acting through potentiation of the 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid receptors. J Med Chem (2010) 0.88
Regulation of hippocampal inhibitory circuits by nicotinic acetylcholine receptors. J Physiol (2011) 0.87
Agomelatine reverses the decrease in hippocampal cell survival induced by chronic mild stress. Behav Brain Res (2010) 0.87
PrPC controls via protein kinase A the direction of synaptic plasticity in the immature hippocampus. J Neurosci (2013) 0.87
Anxiolytic-like action of the antidepressant agomelatine (S 20098) after a social defeat requires the integrity of the SCN. Eur Neuropsychopharmacol (2005) 0.87
"Presynaptic silence" may be golden. Neuropharmacology (2003) 0.86
Signaling properties of stratum oriens interneurons in the hippocampus of transgenic mice expressing EGFP in a subset of somatostatin-containing cells. Hippocampus (2007) 0.86
Anxiolytic-like activity of agomelatine and melatonin in three animal models of anxiety. Behav Pharmacol (2006) 0.86
Memory facilitating effects of agomelatine in the novel object recognition memory paradigm in the rat. Pharmacol Biochem Behav (2011) 0.86
Agomelatine (S20098) modulates the expression of cytoskeletal microtubular proteins, synaptic markers and BDNF in the rat hippocampus, amygdala and PFC. Psychopharmacology (Berl) (2011) 0.85
Presynaptic calcium stores contribute to nicotine-elicited potentiation of evoked synaptic transmission at CA3-CA1 connections in the neonatal rat hippocampus. Hippocampus (2007) 0.84
In the developing rat hippocampus, endogenous activation of presynaptic kainate receptors reduces GABA release from mossy fiber terminals. J Neurosci (2010) 0.84
Developmental regulation of GABAergic signalling in the hippocampus of neuroligin 3 R451C knock-in mice: an animal model of Autism. Front Cell Neurosci (2013) 0.84
Reactive oxygen species mediate the potentiating effects of ATP on GABAergic synaptic transmission in the immature hippocampus. J Biol Chem (2006) 0.84
Differential effects of the novel antidepressant agomelatine (S 20098) versus fluoxetine on 5-HT1A receptors in the rat brain. Neuropharmacology (2004) 0.84
Development of thiophenic analogues of benzothiadiazine dioxides as new powerful potentiators of 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA) receptors. J Med Chem (2013) 0.83
In vivo cross-sectional characterization of cerebral alterations induced by intracerebroventricular administration of streptozotocin. PLoS One (2012) 0.82
S 24795 limits beta-amyloid-alpha7 nicotinic receptor interaction and reduces Alzheimer's disease-like pathologies. Biol Psychiatry (2009) 0.82
The effects of antidepressant treatment in prenatally stressed rats support the glutamatergic hypothesis of stress-related disorders. J Neurosci (2014) 0.82
The antidepressant agomelatine inhibits stress-mediated changes in amino acid efflux in the rat hippocampus and amygdala. Brain Res (2012) 0.82
gamma-Aminobutyric acidA rho receptor subunits in the developing rat hippocampus. J Neurosci Res (2002) 0.81
Chronic agomelatine treatment corrects the abnormalities in the circadian rhythm of motor activity and sleep/wake cycle induced by prenatal restraint stress in adult rats. Int J Neuropsychopharmacol (2012) 0.81
Reprogramming fibroblasts to neural-precursor-like cells by structured overexpression of pallial patterning genes. Mol Cell Neurosci (2013) 0.81
Working memory deficits and related disinhibition of the cAMP/PKA/CREB are alleviated by prefrontal α4β2*-nAChRs stimulation in aged mice. Neurobiol Aging (2013) 0.81
The serotonin1A receptor partial agonist S15535 [4-(benzodioxan-5-yl)1-(indan-2-yl)piperazine] enhances cholinergic transmission and cognitive function in rodents: a combined neurochemical and behavioral analysis. J Pharmacol Exp Ther (2004) 0.81
The mammalian transcriptome and the cellular complexity of the brain. J Physiol (2006) 0.81
Gephyrin selective intrabodies as a new strategy for studying inhibitory receptor clustering. J Mol Neurosci (2007) 0.81
DRUG FOCUS: S 18986: A positive allosteric modulator of AMPA-type glutamate receptors pharmacological profile of a novel cognitive enhancer. CNS Neurosci Ther (2010) 0.80
Chronic stress and antidepressant agomelatine induce region-specific changes in synapsin I expression in the rat brain. J Neurosci Res (2011) 0.80
At immature mossy fibers-CA3 connections, activation of presynaptic GABA(B) receptors by endogenously released GABA contributes to synapses silencing. Front Cell Neurosci (2009) 0.80
Chronic agomelatine and fluoxetine induce antidepressant-like effects in H/Rouen mice, a genetic mouse model of depression. Pharmacol Biochem Behav (2011) 0.80
ATP contributes to the generation of network-driven giant depolarizing potentials in the neonatal rat hippocampus. J Physiol (2005) 0.80
Novel 2-alkylamino-1,4-benzoxazine derivatives as potent neuroprotective agents: structure-activity relationship studies. J Med Chem (2005) 0.79
Effect of extracellular pH on recombinant alpha1beta2gamma2 and alpha1beta2 GABAA receptors. Neuropharmacology (2006) 0.79
Agomelatine suppresses locomotor hyperactivity in olfactory bulbectomised rats: a comparison to melatonin and to the 5-HT(2c) antagonist, S32006. Eur J Pharmacol (2011) 0.79
Agomelatine(S 20098) antagonizes the penile erections induced by the stimulation of 5-HT2C receptors in Wistar rats. Psychopharmacology (Berl) (2003) 0.78
Associative mossy fibre LTP induced by pairing presynaptic stimulation with postsynaptic hyperpolarization of CA3 neurons in rat hippocampal slice. Eur J Neurosci (2003) 0.78
Adenosine down-regulates giant depolarizing potentials in the developing rat hippocampus by exerting a negative control on glutamatergic inputs. J Neurophysiol (2005) 0.78
Activation of nicotinic acetylcholine receptors enhances a slow calcium-dependent potassium conductance and reduces the firing of stratum oriens interneurons. Eur J Neurosci (2009) 0.78
The novel antidepressant agomelatine normalizes hippocampal neuronal activity and promotes neurogenesis in chronically stressed rats. CNS Neurosci Ther (2010) 0.78
Fluoxetine impairs GABAergic signaling in hippocampal slices from neonatal rats. Front Cell Neurosci (2013) 0.78
Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses. Sci Rep (2012) 0.78
Synthesis, pharmacological and structural characterization, and thermodynamic aspects of GluA2-positive allosteric modulators with a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide scaffold. J Med Chem (2013) 0.78
The immature brain needs GABA to be excited and hyper-excited. J Physiol (2011) 0.78
In hippocampal oriens interneurons anti-Hebbian long-term potentiation requires cholinergic signaling via α7 nicotinic acetylcholine receptors. J Neurosci (2013) 0.78