Published in DNA Repair (Amst) on December 11, 2009
Base excision repair: a critical player in many games. DNA Repair (Amst) (2014) 1.08
Nucleosome disruption by DNA ligase III-XRCC1 promotes efficient base excision repair. Mol Cell Biol (2011) 1.07
Rules of engagement for base excision repair in chromatin. J Cell Physiol (2013) 1.03
The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures. Nucleic Acids Res (2015) 0.97
Base excision repair of 8-oxoG in dinucleosomes. Nucleic Acids Res (2011) 0.97
Repair efficiency of (5'S)-8,5'-cyclo-2'-deoxyguanosine and (5'S)-8,5'-cyclo-2'-deoxyadenosine depends on the complementary base. DNA Repair (Amst) (2012) 0.92
Accessing DNA damage in chromatin: Preparing the chromatin landscape for base excision repair. DNA Repair (Amst) (2015) 0.89
Contribution of DNA unwrapping from histone octamers to the repair of oxidatively damaged DNA in nucleosomes. DNA Repair (Amst) (2013) 0.87
Insights into the glycosylase search for damage from single-molecule fluorescence microscopy. DNA Repair (Amst) (2014) 0.85
Impact of abasic site orientation within nucleosomes on human APE1 endonuclease activity. Mutat Res (2014) 0.84
Nucleosomes suppress the formation of double-strand DNA breaks during attempted base excision repair of clustered oxidative damages. J Biol Chem (2014) 0.80
Human cells contain a factor that facilitates the DNA glycosylase-mediated excision of oxidized bases from occluded sites in nucleosomes. DNA Repair (Amst) (2017) 0.80
Facilitation of base excision repair by chromatin remodeling. DNA Repair (Amst) (2015) 0.78
Efficient cleavage of single and clustered AP site lesions within mono-nucleosome templates by CHO-K1 nuclear extract contrasts with retardation of incision by purified APE1. DNA Repair (Amst) (2015) 0.77
Design, synthesis, and characterization of nucleosomes containing site-specific DNA damage. DNA Repair (Amst) (2015) 0.76
Phosphorylation Sites Identified in the NEIL1 DNA Glycosylase Are Potential Targets for the JNK1 Kinase. PLoS One (2016) 0.75
FACT Assists Base Excision Repair by Boosting the Remodeling Activity of RSC. PLoS Genet (2016) 0.75
The Human Ligase IIIα-XRCC1 Protein Complex Performs DNA Nick Repair after Transient Unwrapping of Nucleosomal DNA. J Biol Chem (2017) 0.75
Probing the activity of NTHL1 orthologs by targeting conserved amino acid residues. DNA Repair (Amst) (2017) 0.75
Human OGG1 activity in nucleosomes is facilitated by transient unwrapping of DNA and is influenced by the local histone environment. DNA Repair (Amst) (2017) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature (1997) 44.55
Protein production by auto-induction in high density shaking cultures. Protein Expr Purif (2005) 29.74
The lac repressor-operator interaction. 3. Kinetic studies. J Mol Biol (1970) 10.07
Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 a resolution. J Mol Biol (2002) 8.42
Quality control by DNA repair. Science (1999) 7.71
Base-excision repair of oxidative DNA damage. Nature (2007) 5.44
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol Cell Biol (2000) 5.28
The role of oxidative stress in carcinogenesis. Annu Rev Pharmacol Toxicol (2004) 5.14
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res (2008) 3.48
Non-specific DNA binding of genome regulating proteins as a biological control mechanism: I. The lac operon: equilibrium aspects. Proc Natl Acad Sci U S A (1974) 3.45
AP endonuclease-independent DNA base excision repair in human cells. Mol Cell (2004) 3.37
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA. Proc Natl Acad Sci U S A (2002) 3.33
Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2. J Biol Chem (2003) 2.53
A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification. DNA Repair (Amst) (2007) 2.43
The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair. DNA Repair (Amst) (2007) 2.26
Thymine glycol lesions terminate chain elongation by DNA polymerase I in vitro. Nucleic Acids Res (1986) 2.22
The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase. Proc Natl Acad Sci U S A (2006) 2.17
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro. Nucleic Acids Res (1985) 2.05
DNA bending and a flip-out mechanism for base excision by the helix-hairpin-helix DNA glycosylase, Escherichia coli AlkA. EMBO J (2000) 2.01
A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue. J Biol Chem (2002) 1.89
Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate. EMBO J (2002) 1.87
Oxidative DNA damage repair in mammalian cells: a new perspective. DNA Repair (Amst) (2006) 1.85
Formation of clustered DNA damage after high-LET irradiation: a review. J Radiat Res (2008) 1.76
Single-turnover and pre-steady-state kinetics of the reaction of the adenine glycosylase MutY with mismatch-containing DNA substrates. Biochemistry (1998) 1.75
DNA glycosylase recognition and catalysis. Curr Opin Struct Biol (2004) 1.74
Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes. J Biol Chem (2005) 1.64
Interaction of the human DNA glycosylase NEIL1 with proliferating cell nuclear antigen. The potential for replication-associated repair of oxidized bases in mammalian genomes. J Biol Chem (2007) 1.63
Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1. Biochemistry (2008) 1.62
In vitro nucleotide misinsertion opposite the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin and DNA synthesis past the lesions using Escherichia coli DNA polymerase I (Klenow fragment). Biochemistry (2002) 1.60
Suppressed catalytic activity of base excision repair enzymes on rotationally positioned uracil in nucleosomes. Proc Natl Acad Sci U S A (2003) 1.60
In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites. J Mol Biol (1999) 1.59
The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity. Proc Natl Acad Sci U S A (2004) 1.52
Oxidative stress and apoptosis: a new treatment paradigm in cancer. Front Biosci (2006) 1.52
DNA base excision repair of uracil residues in reconstituted nucleosome core particles. EMBO J (2002) 1.42
The enigma of endonuclease VIII. DNA Repair (Amst) (2003) 1.32
Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer. Carcinogenesis (2004) 1.30
Redox signaling between DNA repair proteins for efficient lesion detection. Proc Natl Acad Sci U S A (2009) 1.30
Replication inhibition and miscoding properties of DNA templates containing a site-specific cis-thymine glycol or urea residue. Chem Res Toxicol (1998) 1.29
Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1. J Biol Chem (2008) 1.27
ATP-dependent chromatin remodeling is required for base excision repair in conventional but not in variant H2A.Bbd nucleosomes. Mol Cell Biol (2007) 1.24
Repair mechanisms for oxidative DNA damage. Front Biosci (2003) 1.22
Sequence dependence for bypass of thymine glycols in DNA by DNA polymerase I. Nucleic Acids Res (1986) 1.18
Electron trap for DNA-bound repair enzymes: a strategy for DNA-mediated signaling. Proc Natl Acad Sci U S A (2006) 1.13
Direct electrochemistry of endonuclease III in the presence and absence of DNA. J Am Chem Soc (2006) 1.12
Initiation of base excision repair of oxidative lesions in nucleosomes by the human, bifunctional DNA glycosylase NTH1. Mol Cell Biol (2007) 1.07
Structural characterization of a viral NEIL1 ortholog unliganded and bound to abasic site-containing DNA. J Biol Chem (2009) 1.01
Rapid determination of the active fraction of DNA repair glycosylases: a novel fluorescence assay for trapped intermediates. Nucleic Acids Res (2007) 0.98
In vitro and in vivo dimerization of human endonuclease III stimulates its activity. J Biol Chem (2003) 0.93
Overproduction, crystallization and preliminary crystallographic analysis of a novel human DNA-repair enzyme that recognizes oxidative DNA damage. Acta Crystallogr D Biol Crystallogr (2004) 0.92
Differential intracellular localization of the human and mouse endonuclease III homologs and analysis of the sorting signals. DNA Repair (Amst) (2002) 0.90
Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radic Biol Med (2008) 3.38
Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta. Proc Natl Acad Sci U S A (2006) 2.51
A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII. DNA Repair (Amst) (2002) 2.41
Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site. EMBO J (2004) 2.14
Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery. J Cell Biol (2006) 1.84
Characterization of a novel metabolic strategy used by drug-resistant tumor cells. FASEB J (2002) 1.76
The cell cycle is a redox cycle: linking phase-specific targets to cell fate. Free Radic Biol Med (2009) 1.75
The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo. Proc Natl Acad Sci U S A (2010) 1.61
A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. Proc Natl Acad Sci U S A (2007) 1.56
The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity. Proc Natl Acad Sci U S A (2004) 1.52
Attempted base excision repair of ionizing radiation damage in human lymphoblastoid cells produces lethal and mutagenic double strand breaks. DNA Repair (Amst) (2004) 1.39
Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts. J Biol Chem (2004) 1.36
Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. J Biol Chem (2006) 1.36
Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNA. Nucleic Acids Res (2011) 1.32
Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides. J Biol Chem (2002) 1.27
The Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damage. Prog Mol Biol Transl Sci (2012) 1.22
Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells. Antioxid Redox Signal (2006) 1.22
Redox regulation of cell-cycle re-entry: cyclin D1 as a primary target for the mitogenic effects of reactive oxygen and nitrogen species. Antioxid Redox Signal (2005) 1.19
Base excision repair by hNTH1 and hOGG1: a two edged sword in the processing of DNA damage in gamma-irradiated human cells. DNA Repair (Amst) (2005) 1.19
tRNA(His) guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc Natl Acad Sci U S A (2010) 1.15
New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas. Am J Pathol (2013) 1.15
Caught bending the A-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Biochemistry (2007) 1.14
Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts. J Mol Biol (2010) 1.12
An extracellular signal-regulated kinase 1- and 2-dependent program of chromatin trafficking of c-Fos and Fra-1 is required for cyclin D1 expression during cell cycle reentry. Mol Cell Biol (2004) 1.12
Nucleosome disruption by DNA ligase III-XRCC1 promotes efficient base excision repair. Mol Cell Biol (2011) 1.07
Bumps in the road: how replicative DNA polymerases see DNA damage. Curr Opin Struct Biol (2005) 1.07
Activated cAMP response element binding protein is overexpressed in human mesotheliomas and inhibits apoptosis. Am J Pathol (2009) 1.07
Oxidative DNA glycosylases: recipes from cloning to characterization. Methods Enzymol (2006) 1.07
Initiation of base excision repair of oxidative lesions in nucleosomes by the human, bifunctional DNA glycosylase NTH1. Mol Cell Biol (2007) 1.07
Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context. J Biol Chem (2013) 1.05
Solution-state NMR investigation of DNA binding interactions in Escherichia coli formamidopyrimidine-DNA glycosylase (Fpg): a dynamic description of the DNA/protein interface. DNA Repair (Amst) (2005) 1.05
Rules of engagement for base excision repair in chromatin. J Cell Physiol (2013) 1.03
The highly conserved tRNAHis guanylyltransferase Thg1p interacts with the origin recognition complex and is required for the G2/M phase transition in the yeast Saccharomyces cerevisiae. Eukaryot Cell (2005) 1.01
Structural characterization of a viral NEIL1 ortholog unliganded and bound to abasic site-containing DNA. J Biol Chem (2009) 1.01
ERK2 is essential for the growth of human epithelioid malignant mesotheliomas. Int J Cancer (2011) 1.00
Human endonuclease VIII-like (NEIL) proteins in the giant DNA Mimivirus. DNA Repair (Amst) (2007) 1.00
The duration of nuclear extracellular signal-regulated kinase 1 and 2 signaling during cell cycle reentry distinguishes proliferation from apoptosis in response to asbestos. Cancer Res (2004) 0.98
Rapid determination of the active fraction of DNA repair glycosylases: a novel fluorescence assay for trapped intermediates. Nucleic Acids Res (2007) 0.98
Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin. Biochemistry (2010) 0.97
Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69. Biochemistry (2010) 0.97
Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis. Mol Cell Biol (2012) 0.97
Neil3, the final frontier for the DNA glycosylases that recognize oxidative damage. Mutat Res (2012) 0.96
Variant base excision repair proteins: contributors to genomic instability. Semin Cancer Biol (2010) 0.96
DNA polymerases provide a canon of strategies for translesion synthesis past oxidatively generated lesions. Curr Opin Struct Biol (2011) 0.96
Structural characterization of viral ortholog of human DNA glycosylase NEIL1 bound to thymine glycol or 5-hydroxyuracil-containing DNA. J Biol Chem (2011) 0.95
Structural characterization of a mouse ortholog of human NEIL3 with a marked preference for single-stranded DNA. Structure (2013) 0.95
Parameters influencing high-efficiency transfection of bacterial artificial chromosomes into cultured mammalian cells. Biotechniques (2003) 0.94
Kinetics of error generation in homologous B-family DNA polymerases. Nucleic Acids Res (2006) 0.94
The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts. DNA Repair (Amst) (2009) 0.93
Asbestos modulates thioredoxin-thioredoxin interacting protein interaction to regulate inflammasome activation. Part Fibre Toxicol (2014) 0.93
Activation of hypoxia-inducible factor-1 protects airway epithelium against oxidant-induced barrier dysfunction. Am J Physiol Lung Cell Mol Physiol (2011) 0.92
Overproduction, crystallization and preliminary crystallographic analysis of a novel human DNA-repair enzyme that recognizes oxidative DNA damage. Acta Crystallogr D Biol Crystallogr (2004) 0.92
Nonphagocytic oxidase 1 causes death in lung epithelial cells via a TNF-RI-JNK signaling axis. Am J Respir Cell Mol Biol (2006) 0.91
Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases. DNA Repair (Amst) (2009) 0.91
Clostridium acetobutylicum 8-oxoguanine DNA glycosylase (Ogg) differs from eukaryotic Oggs with respect to opposite base discrimination. Biochemistry (2008) 0.91
Immunological effects of the TGFβ-blocking antibody GC1008 in malignant pleural mesothelioma patients. Oncoimmunology (2013) 0.91
Estimation of DNA sequence context-dependent mutation rates using primate genomic sequences. J Mol Evol (2007) 0.90
Germ-line variant of human NTH1 DNA glycosylase induces genomic instability and cellular transformation. Proc Natl Acad Sci U S A (2013) 0.90
Nitrogen dioxide enhances allergic airway inflammation and hyperresponsiveness in the mouse. Am J Physiol Lung Cell Mol Physiol (2005) 0.90
Expression and purification of active mouse and human NEIL3 proteins. Protein Expr Purif (2012) 0.89
Crystal structures of two archaeal 8-oxoguanine DNA glycosylases provide structural insight into guanine/8-oxoguanine distinction. Structure (2009) 0.87
IDENTIFICATION OF CONOIDIN A AS A COVALENT INHIBITOR OF PEROXIREDOXIN II. Org Biomol Chem (2009) 0.87
Contribution of DNA unwrapping from histone octamers to the repair of oxidatively damaged DNA in nucleosomes. DNA Repair (Amst) (2013) 0.87
A crystallographic study of the role of sequence context in thymine glycol bypass by a replicative DNA polymerase serendipitously sheds light on the exonuclease complex. J Mol Biol (2011) 0.87
Structural investigation of a viral ortholog of human NEIL2/3 DNA glycosylases. DNA Repair (Amst) (2013) 0.86
Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells. J Cell Physiol (2013) 0.86
Functional analysis of bacterial artificial chromosomes in mammalian cells: mouse Cdc6 is associated with the mitotic spindle apparatus. Genomics (2004) 0.86
The miscoding potential of 5-hydroxycytosine arises due to template instability in the replicative polymerase active site. Biochemistry (2011) 0.85
Structural characterization of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase in its apo form and in complex with 8-oxodeoxyguanosine. J Mol Biol (2009) 0.85
Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. J Clin Invest (2016) 0.85
Engineering functional changes in Escherichia coli endonuclease III based on phylogenetic and structural analyses. J Biol Chem (2005) 0.85
Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanine. DNA Repair (Amst) (2012) 0.84
Decline of nuclear and mitochondrial oxidative base excision repair activity in late passage human diploid fibroblasts. DNA Repair (Amst) (2003) 0.84
Evidence that the pre-mRNA splicing factor Clf1p plays a role in DNA replication in Saccharomyces cerevisiae. Genetics (2002) 0.83
S-phase arrest by reactive nitrogen species is bypassed by okadaic acid, an inhibitor of protein phosphatases PP1/PP2A. Free Radic Biol Med (2005) 0.83
Modulation of Sp1-dependent transcription by a cis-acting E2F element in dhfr promoter. Biochem Biophys Res Commun (2003) 0.82
Reactive nitrogen species block cell cycle re-entry through sustained production of hydrogen peroxide. Am J Respir Cell Mol Biol (2003) 0.82
A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates. Anal Biochem (2013) 0.81
A novel bicistronic vector for overexpressing Mycobacterium tuberculosis proteins in Escherichia coli. Protein Expr Purif (2008) 0.80
Inhibitory effects of novel E2F decoy oligodeoxynucleotides on mesangial cell proliferation by coexpression of E2F/DP. Biochem Biophys Res Commun (2003) 0.80
The C-terminal lysine of Ogg2 DNA glycosylases is a major molecular determinant for guanine/8-oxoguanine distinction. J Mol Biol (2010) 0.80
A new technique for the quantitative assessment of 8-oxoguanine in nuclear DNA as a marker of oxidative stress. Application to dystrophin-deficient DMD skeletal muscles. Histochem Cell Biol (2005) 0.80
Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase. DNA Repair (Amst) (2009) 0.79
Manipulating genes and gene copy number by bacterial artificial chromosomes transfection. Methods Mol Biol (2007) 0.77
Base excision repair: NMR backbone assignments of Escherichia coli formamidopyrimidine-DNA glycosylase. J Biomol NMR (2002) 0.77
Chemical footprinting of structural and functional elements of dhfr oribeta during the CHOC 400 cell cycle. Gene (2004) 0.76
The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures. Nucleic Acids Res (2015) 0.75
Using shifts in amino acid frequency and substitution rate to identify latent structural characters in base-excision repair enzymes. PLoS One (2011) 0.75
Baculovirus P35 inhibits NO-induced apoptosis in activated macrophages by inhibiting cytochrome c release. J Cell Sci (2004) 0.75