Published in J Neurosci on December 09, 2009
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Lis1 is an initiation factor for dynein-driven organelle transport. J Cell Biol (2012) 1.75
Genetic mosaic dissection of Lis1 and Ndel1 in neuronal migration. Neuron (2010) 1.58
What disorders of cortical development tell us about the cortex: one plus one does not always make two. Curr Opin Genet Dev (2011) 1.45
Lissencephaly: mechanistic insights from animal models and potential therapeutic strategies. Semin Cell Dev Biol (2010) 1.21
Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction. J Neurosci (2010) 1.12
Distinct alpha- and beta-tubulin isotypes are required for the positioning, differentiation and survival of neurons: new support for the 'multi-tubulin' hypothesis. Biosci Rep (2010) 1.11
Neuronal migration defects in the Loa dynein mutant mouse. Neural Dev (2011) 1.11
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14-3-3ε and ζ regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain. J Neurosci (2014) 0.92
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LIS1 and DCX: Implications for Brain Development and Human Disease in Relation to Microtubules. Scientifica (Cairo) (2013) 0.85
Disc1 variation leads to specific alterations in adult neurogenesis. PLoS One (2014) 0.85
Molecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical Development. Front Neurosci (2015) 0.84
Microtubules and Lis-1/NudE/dynein regulate invasive cell-on-cell migration in Drosophila. PLoS One (2012) 0.84
The cytoskeleton and neurite initiation. Bioarchitecture (2014) 0.83
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Microtubule plus-end tracking proteins in neuronal development. Cell Mol Life Sci (2016) 0.77
Cytoplasmic dynein and its regulatory proteins in Golgi pathology in nervous system disorders. Front Neurosci (2015) 0.76
Lis1 reduction causes tangential migratory errors in mouse spinal cord. J Comp Neurol (2012) 0.75
Status epilepticus stimulates NDEL1 expression via the CREB/CRE pathway in the adult mouse brain. Neuroscience (2016) 0.75
Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex. Development (2016) 0.75
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Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells. Cell (2005) 4.86
A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. Neuron (2000) 3.93
Mitotic spindle regulation by Nde1 controls cerebral cortical size. Neuron (2004) 3.90
Trekking across the brain: the journey of neuronal migration. Cell (2007) 3.90
Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality. Nat Genet (1998) 3.89
Dual subcellular roles for LIS1 and dynein in radial neuronal migration in live brain tissue. Nat Neurosci (2007) 3.47
NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron (2000) 3.45
Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning. Neuron (2004) 3.33
LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages. J Cell Biol (2005) 3.11
Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration. J Cell Biol (2004) 3.01
Two modes of radial migration in early development of the cerebral cortex. Nat Neurosci (2001) 2.70
Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division. Cell (2008) 2.68
Lissencephaly and LIS1: insights into the molecular mechanisms of neuronal migration and development. Clin Genet (2007) 2.50
Cytoskeletal coordination during neuronal migration. Proc Natl Acad Sci U S A (2005) 2.47
Life is a journey: a genetic look at neocortical development. Nat Rev Genet (2002) 2.46
Modes of neuronal migration in the developing cerebral cortex. Nat Rev Neurosci (2002) 2.41
14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet (2003) 2.27
Multiple dose-dependent effects of Lis1 on cerebral cortical development. J Neurosci (2003) 1.81
The cellular roles of the lissencephaly gene LIS1, and what they tell us about brain development. Genes Dev (2006) 1.78
Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality. Mol Cell Biol (2005) 1.71
NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment. Mol Cell Biol (2006) 1.69
Cytoplasmic dynein and LIS1 are required for microtubule advance during growth cone remodeling and fast axonal outgrowth. J Neurosci (2007) 1.67
Human Nudel and NudE as regulators of cytoplasmic dynein in poleward protein transport along the mitotic spindle. Mol Cell Biol (2003) 1.61
NudEL targets dynein to microtubule ends through LIS1. Nat Cell Biol (2005) 1.53
Neuronal migration in the developing cerebral cortex: observations based on real-time imaging. Cereb Cortex (2003) 1.47
Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination. Hum Mol Genet (2008) 1.45
Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration. Hum Mol Genet (2005) 1.45
Targeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerization. Proc Natl Acad Sci U S A (2001) 1.44
An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics. Nat Cell Biol (2009) 1.31
alpha3beta1 integrin modulates neuronal migration and placement during early stages of cerebral cortical development. Development (2004) 1.28
Layering defect in p35 deficiency is linked to improper neuronal-glial interaction in radial migration. Nat Neurosci (2003) 1.13
Neuregulin signaling regulates neural precursor growth and the generation of oligodendrocytes in vitro. J Neurosci (2001) 1.13
Ndel1 controls the dynein-mediated transport of vimentin during neurite outgrowth. J Biol Chem (2008) 1.01
Effects of acidic and basic fibroblast growth factors (aFGF, bFGF) on glial precursor cell proliferation: age dependency and brain region specificity. Dev Biol (1992) 0.91
IKK-beta links inflammation to obesity-induced insulin resistance. Nat Med (2005) 12.07
JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity. Cell Metab (2007) 5.38
An expressed pseudogene regulates the messenger-RNA stability of its homologous coding gene. Nature (2003) 3.90
Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development. Cell (2002) 3.37
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development (2007) 3.28
Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration. J Cell Biol (2004) 3.01
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development (2006) 2.96
Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development. Nat Neurosci (2004) 2.81
Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure. Development (2002) 2.71
Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division. Cell (2008) 2.68
Life is a journey: a genetic look at neocortical development. Nat Rev Genet (2002) 2.46
Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway. Nat Genet (2005) 2.36
Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. PLoS Genet (2008) 2.29
14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet (2003) 2.27
Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1. Neuron (2002) 1.96
Doublecortin is required in mice for lamination of the hippocampus but not the neocortex. J Neurosci (2002) 1.94
N-glycolylneuraminic acid deficiency in mice: implications for human biology and evolution. Mol Cell Biol (2007) 1.87
Immunoglobulin class switch recombination is impaired in Atm-deficient mice. J Exp Med (2004) 1.87
DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1. J Neurosci (2007) 1.84
Planar polarization of node cells determines the rotational axis of node cilia. Nat Cell Biol (2010) 1.83
Multiple dose-dependent effects of Lis1 on cerebral cortical development. J Neurosci (2003) 1.81
LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein. EMBO J (2008) 1.72
Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality. Mol Cell Biol (2005) 1.71
NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment. Mol Cell Biol (2006) 1.69
Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway. Proc Natl Acad Sci U S A (2003) 1.68
Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality. Mol Cell Biol (2002) 1.66
Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3. Am J Hum Genet (2003) 1.61
Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Nat Genet (2007) 1.59
Genetic mosaic dissection of Lis1 and Ndel1 in neuronal migration. Neuron (2010) 1.58
Interaction of reelin signaling and Lis1 in brain development. Nat Genet (2003) 1.56
The phosphatase PP4c controls spindle orientation to maintain proliferative symmetric divisions in the developing neocortex. Neuron (2013) 1.55
Role of 14-3-3 proteins in eukaryotic signaling and development. Curr Top Dev Biol (2005) 1.53
Cancer chemoprevention by the antioxidant tempol in Atm-deficient mice. Hum Mol Genet (2004) 1.50
Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination. Hum Mol Genet (2008) 1.45
Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration. Hum Mol Genet (2005) 1.45
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility. Nat Neurosci (2005) 1.41
The 2q23.1 microdeletion syndrome: clinical and behavioural phenotype. Eur J Hum Genet (2009) 1.39
Disregulated RhoGTPases and actin cytoskeleton contribute to the migration defect in Lis1-deficient neurons. J Neurosci (2003) 1.38
Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Genet (2012) 1.37
An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics. Nat Cell Biol (2009) 1.31
TBX1 is required for inner ear morphogenesis. Hum Mol Genet (2003) 1.30
Mnt-Max to Myc-Max complex switching regulates cell cycle entry. J Cell Biol (2005) 1.25
Identification of YWHAE, a gene encoding 14-3-3epsilon, as a possible susceptibility gene for schizophrenia. Hum Mol Genet (2008) 1.23
Lissencephaly: mechanistic insights from animal models and potential therapeutic strategies. Semin Cell Dev Biol (2010) 1.21
The canonical Wnt pathway in early mammalian embryogenesis and stem cell maintenance/differentiation. Curr Opin Genet Dev (2004) 1.21
Cortical dysplasia of the left temporal lobe might explain severe expressive-language delay in patients with duplication of the Williams-Beuren locus. Eur J Hum Genet (2006) 1.18
Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis. EMBO J (2003) 1.17
Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation. J Cell Biol (2008) 1.17
A new role for expressed pseudogenes as ncRNA: regulation of mRNA stability of its homologous coding gene. J Mol Med (Berl) (2004) 1.16
Sialyltransferase ST8Sia-II assembles a subset of polysialic acid that directs hippocampal axonal targeting and promotes fear behavior. J Biol Chem (2004) 1.16
Behavior of mice with mutations in the conserved region deleted in velocardiofacial/DiGeorge syndrome. Neurogenetics (2006) 1.14
Two classes of low-copy repeats comediate a new recurrent rearrangement consisting of duplication at 8p23.1 and triplication at 8p23.2. Hum Mutat (2007) 1.14
Chromosomal rearrangements in Xq and premature ovarian failure: mapping of 25 new cases and review of the literature. Hum Reprod (2006) 1.14
Previously uncharacterized roles of platelet-activating factor acetylhydrolase 1b complex in mouse spermatogenesis. Proc Natl Acad Sci U S A (2003) 1.13
Reciprocal translocations: a trap for cytogenetists? Hum Genet (2005) 1.12
Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction. J Neurosci (2010) 1.12
Lis1 is necessary for normal non-radial migration of inhibitory interneurons. Am J Pathol (2004) 1.08
Wnt signaling in mammalian development: lessons from mouse genetics. Cold Spring Harb Perspect Biol (2012) 1.06
Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly. Nat Med (2009) 1.04
Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein. J Cell Sci (2011) 1.02
Kinesin-1 regulates dendrite microtubule polarity in Caenorhabditis elegans. Elife (2013) 1.01
mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1. EMBO J (2009) 1.01
Analysis of non-radial interneuron migration dynamics and its disruption in Lis1+/- mice. J Comp Neurol (2006) 1.00
CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity. J Neurochem (2009) 1.00
RAG-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice. Mol Cell Biol (2002) 1.00
Cancer chemoprevention by the antioxidant tempol acts partially via the p53 tumor suppressor. Hum Mol Genet (2005) 1.00
Loss of the Max-interacting protein Mnt in mice results in decreased viability, defective embryonic growth and craniofacial defects: relevance to Miller-Dieker syndrome. Hum Mol Genet (2004) 1.00
Carbonic anhydrase III is not required in the mouse for normal growth, development, and life span. Mol Cell Biol (2004) 0.97
Microphthalmia with linear skin defects (MLS) syndrome: clinical, cytogenetic, and molecular characterization of 11 cases. Am J Med Genet A (2005) 0.97
An inbred 129SvEv GFPCre transgenic mouse that deletes loxP-flanked genes in all tissues. Nucleic Acids Res (2003) 0.96
Disheveled mediated planar cell polarity signaling is required in the second heart field lineage for outflow tract morphogenesis. Dev Biol (2012) 0.96
The Pafah1b complex interacts with the reelin receptor VLDLR. PLoS One (2007) 0.96
Dysmorphic features, simplified gyral pattern and 7q11.23 duplication reciprocal to the Williams-Beuren deletion. Eur J Hum Genet (2008) 0.95
LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex. Hum Mol Genet (2013) 0.95
Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling. Science (2013) 0.95
The essential role of LIS1, NDEL1 and Aurora-A in polarity formation and microtubule organization during neurogensis. Cell Adh Migr (2010) 0.94
Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression. Cancer Res (2006) 0.94
A 2.3 Mb duplication of chromosome 8q24.3 associated with severe mental retardation and epilepsy detected by standard karyotype. Eur J Hum Genet (2005) 0.94
Functional dissection of LIS1 and NDEL1 towards understanding the molecular mechanisms of cytoplasmic dynein regulation. J Biol Chem (2010) 0.94
Epigenetic control of the critical region for premature ovarian failure on autosomal genes translocated to the X chromosome: a hypothesis. Hum Genet (2007) 0.91