Published in Mol Cell Proteomics on December 14, 2009
Top-down proteomics in health and disease: challenges and opportunities. Proteomics (2014) 1.08
Mapping surface accessibility of the C1r/C1s tetramer by chemical modification and mass spectrometry provides new insights into assembly of the human C1 complex. J Biol Chem (2010) 0.94
Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites. Proc Natl Acad Sci U S A (2013) 0.94
Deciphering the fine details of c1 assembly and activation mechanisms: "mission impossible"? Front Immunol (2014) 0.90
Development of a novel method for analyzing collagen O-glycosylations by hydrazide chemistry. Mol Cell Proteomics (2012) 0.89
Structural and Functional Characterization of a Single-Chain Form of the Recognition Domain of Complement Protein C1q. Front Immunol (2016) 0.75
A collagen-like amino acid sequence in a polypeptide chain of human C1q (a subcomponent of the first component of complement). Biochem J (1974) 2.53
Subunit composition and structure of subcomponent C1q of the first component of human complement. Biochem J (1976) 2.46
The classical complement pathway: activation and regulation of the first complement component. Adv Immunol (1985) 2.38
Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. J Proteome Res (2005) 2.35
Mining a tandem mass spectrometry database to determine the trends and global factors influencing peptide fragmentation. Anal Chem (2003) 2.28
Complement activation and inhibition: a delicate balance. Trends Immunol (2009) 2.22
Statistical characterization of ion trap tandem mass spectra from doubly charged tryptic peptides. Anal Chem (2003) 2.20
The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties. J Biol Chem (2003) 2.02
C1q: structure, function, and receptors. Immunopharmacology (2000) 1.89
Differential elution of Clq, Clr and Cls from human Cl bound to immune aggregates. Use in the rapid purification of Cl subcomponents. Mol Immunol (1979) 1.78
Complement proteins C1q and MBL are pattern recognition molecules that signal immediate and long-term protective immune functions. Mol Immunol (2006) 1.61
Structure and activation of the C1 complex of complement: unraveling the puzzle. Trends Immunol (2004) 1.59
Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement. Biochem J (1979) 1.45
Top-down protein sequencing and MS3 on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer. Mol Cell Proteomics (2006) 1.43
Inhibition of the reconstitution of the haemolytic activity of the first component of human complement by a pepsin-derived fragment of subcomponent C1q. Biochem J (1977) 1.40
Overalkylation of a protein digest with iodoacetamide. Anal Chem (2001) 1.36
Ultrastructure of the first component of human complement: electron microscopy of the crosslinked complex. Proc Natl Acad Sci U S A (1982) 1.30
Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q. Biochem J (1991) 1.29
The classical and regulatory functions of C1q in immunity and autoimmunity. Cell Mol Immunol (2008) 1.26
The asparagine-linked sugar chains of subcomponent C1q of the first component of human complement. J Biol Chem (1978) 1.22
An integrated top-down and bottom-up strategy for broadly characterizing protein isoforms and modifications. J Proteome Res (2009) 1.21
X-ray structure of the Ca2+-binding interaction domain of C1s. Insights into the assembly of the C1 complex of complement. J Biol Chem (2003) 1.21
Adiponectin multimerization is dependent on conserved lysines in the collagenous domain: evidence for regulation of multimerization by alterations in posttranslational modifications. Mol Endocrinol (2006) 1.20
Assembly of subcomponents C1r and C1s of first component of complement: electron microscopic and ultracentrifugal studies. Proc Natl Acad Sci U S A (1980) 1.17
Investigating MS2/MS3 matching statistics: a model for coupling consecutive stage mass spectrometry data for increased peptide identification confidence. Mol Cell Proteomics (2007) 1.17
On the benefits of acquiring peptide fragment ions at high measured mass accuracy. J Am Soc Mass Spectrom (2008) 1.17
Amino acid sequence of the N-terminal forty-two amino acid residues of the C chain of subcomponent C1q of the first component of human complement. Biochem J (1977) 1.13
Identification of the C1q-binding Sites of Human C1r and C1s: a refined three-dimensional model of the C1 complex of complement. J Biol Chem (2009) 1.13
Hydroxylysine-linked glycosides of human complement subcomponent C1q and various collagens. Biochem J (1979) 1.11
Amino acid sequence of the N-terminal 108 amino acid residues of the B chain of subcomponent C1q of the first component of human complement. Biochem J (1978) 1.09
Beta-amyloid fibrils activate the C1 complex of complement under physiological conditions: evidence for a binding site for A beta on the C1q globular regions. J Immunol (2001) 1.07
Measurement of the association constants of the complexes formed between intact C1q or pepsin-treated C1q stalks and the unactivated or activated C1r2C1s2 tetramers. Mol Immunol (1983) 1.02
Neutron scattering studies of subcomponent C1q of first component C1 of human complement and its association with subunit C1r2C1s2 within C1. J Mol Biol (1984) 1.02
Identification of the site of human mannan-binding lectin involved in the interaction with its partner serine proteases: the essential role of Lys55. J Immunol (2007) 0.99
Completion of the amino acid sequences of the A and B chains of subcomponent C1q of the first component of human complement. Biochem J (1982) 0.95
C1, MBL-MASPs and C1-inhibitor: novel approaches for targeting complement-mediated inflammation. Trends Mol Med (2008) 0.95
Assembly of C1 and the MBL- and ficolin-MASP complexes: structural insights. Immunobiology (2006) 0.93
NH2-terminal calcium-binding domain of human complement C1s- mediates the interaction of C1r- with C1q. Biochemistry (1990) 0.93
Conformation and restricted segmental flexibility of C1, the first component of human complement. J Mol Biol (1983) 0.92
Mass spectrometry analysis of the oligomeric C1q protein reveals the B chain as the target of trypsin cleavage and interaction with fucoidan. Biochemistry (2005) 0.88
Structural characterization of bovine collectin-43. Eur J Biochem (1997) 0.87
Activation of human complement serine-proteinase C1r is down-regulated by a Ca(2+)-dependent intramolecular control that is released in the C1 complex through a signal transmitted by C1q. Biochem J (1994) 0.85
Neutron scattering studies of the isolated C1r2C1s2 subunit of first component of human complement in solution. Proc Natl Acad Sci U S A (1983) 0.85
Chemical studies on the isolated collagen-like and globular fragment of complement component C1q. Comparative studies on bovine and human C1q. Biochim Biophys Acta (1983) 0.84
Interaction of fucoidan with the proteins of the complement classical pathway. Biochim Biophys Acta (2003) 0.84
A monoclonal antibody to C1q which appears to interact with C1r2C1s2-binding site. FEBS Lett (1988) 0.81
Structural characterization of human and bovine lung surfactant protein D. Biochem J (1999) 0.80
Chemical characterization and location of ionic interactions involved in the assembly of the C1 complex of human complement. J Protein Chem (1993) 0.79
Primary structure of the helical domain of porcine collagen X. Matrix Biol (1999) 0.78
Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA. Cell (2011) 4.11
Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice. J Neurosci (2003) 2.85
The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties. J Biol Chem (2003) 2.02
Structure and activation of the C1 complex of complement: unraveling the puzzle. Trends Immunol (2004) 1.59
C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition. J Immunol (2008) 1.59
Structural insights into the innate immune recognition specificities of L- and H-ficolins. EMBO J (2007) 1.53
EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells. Biochem J (2003) 1.50
Systematic identification of mitochondrial proteins by LC-MS/MS. Anal Chem (2002) 1.24
X-ray structure of the Ca2+-binding interaction domain of C1s. Insights into the assembly of the C1 complex of complement. J Biol Chem (2003) 1.21
Interactions of the extracellular matrix proteoglycans decorin and biglycan with C1q and collectins. J Immunol (2005) 1.19
Carbohydrate recognition properties of human ficolins: glycan array screening reveals the sialic acid binding specificity of M-ficolin. J Biol Chem (2009) 1.16
Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling. J Biol Chem (2004) 1.16
Human astrovirus coat protein binds C1q and MBL and inhibits the classical and lectin pathways of complement activation. Mol Immunol (2009) 1.14
Major phosphorylation of SF1 on adjacent Ser-Pro motifs enhances interaction with U2AF65. FEBS J (2006) 1.13
Identification of the C1q-binding Sites of Human C1r and C1s: a refined three-dimensional model of the C1 complex of complement. J Biol Chem (2009) 1.13
Proteomic analysis of the tetraspanin web using LC-ESI-MS/MS and MALDI-FTICR-MS. Proteomics (2006) 1.13
Molecular organization of human Ficolin-2. Mol Immunol (2006) 1.11
Interaction of C1q and mannan-binding lectin with viruses. Immunobiology (2002) 1.09
Modified low density lipoproteins differentially bind and activate the C1 complex of complement. Mol Immunol (2006) 1.08
Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins. J Biol Chem (2008) 1.08
Complement protein C1q induces maturation of human dendritic cells. Mol Immunol (2007) 1.06
Evidence that complement protein C1q interacts with C-reactive protein through its globular head region. J Immunol (2006) 1.05
Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch. J Biol Chem (2007) 1.04
X-ray structure of the human calreticulin globular domain reveals a peptide-binding area and suggests a multi-molecular mechanism. PLoS One (2011) 1.02
Sulfated oligosaccharides (heparin and fucoidan) binding and dimerization of stromal cell-derived factor-1 (SDF-1/CXCL 12) are coupled as evidenced by affinity CE-MS analysis. Glycobiology (2008) 1.01
Studies on the interactions between C-reactive protein and complement proteins. Immunology (2007) 1.01
The two major oligomeric forms of human mannan-binding lectin: chemical characterization, carbohydrate-binding properties, and interaction with MBL-associated serine proteases. J Immunol (2005) 1.00
Investigations on the C1q-calreticulin-phosphatidylserine interactions yield new insights into apoptotic cell recognition. J Mol Biol (2011) 1.00
Identification of the site of human mannan-binding lectin involved in the interaction with its partner serine proteases: the essential role of Lys55. J Immunol (2007) 0.99
Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism. Structure (2002) 0.98
Quantitative proteomic analysis of lentiviral vectors using 2-DE. Proteomics (2009) 0.98
Characterization of recombinant mannan-binding lectin-associated serine protease (MASP)-3 suggests an activation mechanism different from that of MASP-1 and MASP-2. J Immunol (2004) 0.98
M-ficolin interacts with the long pentraxin PTX3: a novel case of cross-talk between soluble pattern-recognition molecules. J Immunol (2011) 0.96
Mapping surface accessibility of the C1r/C1s tetramer by chemical modification and mass spectrometry provides new insights into assembly of the human C1 complex. J Biol Chem (2010) 0.94
Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites. Proc Natl Acad Sci U S A (2013) 0.94
Cutting edge: C1q binds deoxyribose and heparan sulfate through neighboring sites of its recognition domain. J Immunol (2010) 0.94
Assembly of C1 and the MBL- and ficolin-MASP complexes: structural insights. Immunobiology (2006) 0.93
The X-ray structure of human mannan-binding lectin-associated protein 19 (MAp19) and its interaction site with mannan-binding lectin and L-ficolin. J Biol Chem (2004) 0.93
Structural insights into the recognition properties of human ficolins. J Innate Immun (2009) 0.92
Differentiation of the fucoidan sulfated L-fucose isomers constituents by CE-ESIMS and molecular modeling. Carbohydr Res (2006) 0.92
Characterization of a new alpha-L-fucosidase isolated from the marine mollusk Pecten maximus that catalyzes the hydrolysis of alpha-L-fucose from algal fucoidan (Ascophyllum nodosum). Glycobiology (2002) 0.92
The human c1q globular domain: structure and recognition of non-immune self ligands. Front Immunol (2012) 0.91
Complement protein C1q recognizes a conformationally modified form of the prion protein. Biochemistry (2005) 0.91
Structural and functional characterization of the recombinant human mitochondrial trifunctional protein. Biochemistry (2010) 0.90
Tetraspanins connect several types of Ig proteins: IgM is a novel component of the tetraspanin web on B-lymphoid cells. Cancer Immunol Immunother (2004) 0.90
New 7-methylguanine derivatives targeting the influenza polymerase PB2 cap-binding domain. J Med Chem (2013) 0.89
Characterization of the interaction between L-ficolin/p35 and mannan-binding lectin-associated serine proteases-1 and -2. J Immunol (2002) 0.89
Mass spectrometry analysis of the oligomeric C1q protein reveals the B chain as the target of trypsin cleavage and interaction with fucoidan. Biochemistry (2005) 0.88
The lectin-like activity of human C1q and its implication in DNA and apoptotic cell recognition. FEBS Lett (2008) 0.87
Structure and properties of the Ca(2+)-binding CUB domain, a widespread ligand-recognition unit involved in major biological functions. Biochem J (2011) 0.87
Performance evaluation on a wide set of matrix-assisted laser desorption ionization matrices for the detection of oligosaccharides in a high-throughput mass spectrometric screening of carbohydrate depolymerizing enzymes. Rapid Commun Mass Spectrom (2011) 0.87
Frontal analysis capillary electrophoresis hyphenated to electrospray ionization mass spectrometry for the characterization of the antithrombin/heparin pentasaccharide complex. Anal Chem (2007) 0.86
Complement protein C1q forms a complex with cytotoxic prion protein oligomers. J Biol Chem (2010) 0.86
Trimeric reassembly of the globular domain of human C1q. Biochim Biophys Acta (2007) 0.85
Complement protein C1q recognizes enzymatically modified low-density lipoprotein through unesterified fatty acids generated by cholesterol esterase. Biochemistry (2010) 0.85
Hydrogen/deuterium exchange mass spectrometric analysis of conformational changes accompanying the assembly of the yeast prion Ure2p into protein fibrils. J Mol Biol (2007) 0.85
An Sfi1p-like centrin-binding protein mediates centrin-based Ca2+ -dependent contractility in Paramecium tetraurelia. Eukaryot Cell (2007) 0.84
Proteins of the innate immune system crystallize on carbon nanotubes but are not activated. ACS Nano (2011) 0.84
Biological properties of sulfated fucans: the potent inhibiting activity of algal fucoidan against the human compliment system. Glycobiology (2003) 0.84
Interaction of fucoidan with the proteins of the complement classical pathway. Biochim Biophys Acta (2003) 0.84
NMR characterization and molecular modeling of fucoidan showing the importance of oligosaccharide branching in its anticomplementary activity. Glycobiology (2010) 0.83
Nanovesicles released by Dictyostelium cells: a potential carrier for drug delivery. Int J Pharm (2009) 0.83
HSulf sulfatases catalyze processive and oriented 6-O-desulfation of heparan sulfate that differentially regulates fibroblast growth factor activity. FASEB J (2013) 0.83
A spectroscopic and voltammetric study of the pH-dependent Cu(II) coordination to the peptide GGGTH: relevance to the fifth Cu(II) site in the prion protein. J Biol Inorg Chem (2006) 0.82
Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice. J Neurochem (2004) 0.82
Effects of toxic extracts and purified borbotoxins from Prorocentrum borbonicum (Dinophyceae) on vertebrate neuromuscular junctions. Toxicon (2002) 0.82
HABA-based ionic liquid matrices for UV-MALDI-MS analysis of heparin and heparan sulfate oligosaccharides. Glycobiology (2009) 0.81
Interaction of the C1 complex of complement with sulfated polysaccharide and DNA probed by single molecule fluorescence microscopy. Eur J Biochem (2003) 0.81
Kinetics of enzymatic degradation of high molecular weight polysaccharides through a nanopore: experiments and data-modeling. Anal Chem (2013) 0.81
Hexacyanometalate molecular chemistry: heptanuclear heterobimetallic complexes; control of the ground spin state. Chemistry (2003) 0.81
The human large subunit ribosomal protein L36A-like contacts the CCA end of P-site bound tRNA. Biochimie (2009) 0.81
The chaperone and potential mannan-binding lectin (MBL) co-receptor calreticulin interacts with MBL through the binding site for MBL-associated serine proteases. FEBS J (2008) 0.80
Functional characterization of the recombinant human C1 inhibitor serpin domain: insights into heparin binding. J Immunol (2010) 0.80
Single molecule detection of glycosaminoglycan hyaluronic acid oligosaccharides and depolymerization enzyme activity using a protein nanopore. ACS Nano (2012) 0.80
CD98, a novel marker of transient amplifying human keratinocytes. Proteomics (2005) 0.80
Linking the proteins--elucidation of proteome-scale networks using mass spectrometry. Mass Spectrom Rev (2010) 0.80
Functional role of the linker between the complement control protein modules of complement protease C1s. J Immunol (2005) 0.80
Identification of novel PAMP-triggered phosphorylation and dephosphorylation events in Arabidopsis thaliana by quantitative phosphoproteomic analysis. J Proteome Res (2014) 0.79
Hydrophobic pockets at the membrane interface: an original mechanism for membrane protein interactions. Biochemistry (2004) 0.79
Characterization of toxins within crude venoms by combined use of Fourier transform mass spectrometry and cloning. Anal Chem (2005) 0.79
The polyethylene oxide capillary coating is compatible with capillary electrophoresis-mass spectrometry analysis of basic proteins. Anal Biochem (2007) 0.79